KEGG REACTION: R10032

REACTION: R10032

Entry

R10032                      Reaction

Name

N-hydroxy-L-valine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating)

Definition

N-Hydroxy-L-valine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N,N-Dihydroxy-L-valine + [Oxidized NADPH---hemoprotein reductase] + H2O

Equation

C20313 + C00007 + C03024 <=> C20314 + C03161 + C00001

Comment

the second step of three-step reaction (see R08663, R10031+R10032+R10033)

Reaction class

RC00001

C00005_C00006

RC01918

C20313_C20314

Enzyme

1.14.14.38 1.14.14.39

Pathway

rn00460

Cyanoamino acid metabolism

rn01100

Metabolic pathways

rn01110

Biosynthesis of secondary metabolites

Brite

Enzymatic reactions [BR:br08201]
1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.38
     R10032  N-Hydroxy-L-valine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N,N-Dihydroxy-L-valine + [Oxidized NADPH---hemoprotein reductase] + H2O
    1.14.14.39
     R10032  N-Hydroxy-L-valine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N,N-Dihydroxy-L-valine + [Oxidized NADPH---hemoprotein reductase] + H2O

Orthology

K13401

valine N-monooxygenase [EC:1.14.14.38]

K14984

isoleucine N-monooxygenase [EC:1.14.14.39]

Other DBs

RHEA:

30498

LinkDB

RCLASS: RC01918

Entry

RC01918                     RClass

Definition

N1b-N1c:*-O1b:C1c+O1b-C1c+O1b

Reactant pair

C03004_C15503 C19712_C19715 C19716_C19717
C20310_C20311 C20313_C20314 C21536_C21537

Related class

Reaction

R04460 R09580 R09584 R10028 R10032 R11648

Enzyme

1.14.14.36 1.14.14.38 1.14.14.39 1.14.14.40
1.14.14.42 1.14.14.156