KEGG   REACTION: R10079
Entry
R10079                      Reaction                               
Name
carbamate hydro-lyase;
cyanate hydratase
Definition
Cyanate + HCO3- + H+ <=> Ammonia + 2 CO2
Equation
C01417 + C00288 + C00080 <=> C00014 + 2 C00011
Comment
two-step reaction (see R03546+R07316)
bicarbonate is recycled (see R10092)
Reaction class
RC02807  C00011_C00288
Enzyme
4.2.1.104
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.104
     R10079  Cyanate + HCO3- + H+ <=> Ammonia + 2 CO2
Orthology
K01725  cyanate lyase [EC:4.2.1.104]
LinkDB

KEGG   REACTION: R03546
Entry
R03546                      Reaction                               
Name
carbamate hydro-lyase;
cyanate hydratase;
cyanate C-N-lyase
Definition
Cyanate + H+ + HCO3- <=> CO2 + Carbamate
Equation
C01417 + C00080 + C00288 <=> C00011 + C01563
Comment
first step of two-step reaction (see R10079, R03546+R07316)
bicarbonate is recycled (see R10092)
Reaction class
RC00952  C01417_C01563
RC02807  C00011_C00288
Enzyme
4.2.1.104
Pathway
rn00910  Nitrogen metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.104
     R03546  Cyanate + H+ + HCO3- <=> CO2 + Carbamate
Orthology
K01725  cyanate lyase [EC:4.2.1.104]
Reference
1  [PMID:3110153]
  Authors
Johnson WV, Anderson PM.
  Title
Bicarbonate is a recycling substrate for cyanase.
  Journal
J Biol Chem 262:9021-5 (1987)
Reference
2  [PMID:7947823]
  Authors
Anderson PM, Korte JJ, Holcomb TA.
  Title
Reaction of the N-terminal methionine residues in cyanase with diethylpyrocarbonate.
  Journal
Biochemistry 33:14121-5 (1994)
DOI:10.1021/bi00251a022
Other DBs
RHEA: 17404 18492
LinkDB

KEGG   REACTION: R07316
Entry
R07316                      Reaction                               
Definition
Carbamate <=> Ammonia + CO2
Equation
C01563 <=> C00014 + C00011
Comment
spontaneous
the second step of two-step reaction (see R12625, R09980+R07316 / R12623, R12624+R07316 / R10079, R03546+R07316)
Enzyme
3.5.1.110       4.2.1.104
Pathway
rn00910  Nitrogen metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.110
     R07316  Carbamate <=> Ammonia + CO2
 4. Lyase reactions
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.104
     R07316  Carbamate <=> Ammonia + CO2
Other DBs
RHEA: 15652
LinkDB

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