KEGG   REACTION: R10243
Entry
R10243                      Reaction                               
Definition
Tetrahydrofolate + Acetyl-CoA <=> 5-Methyltetrahydrofolate + CoA + CO
Equation
C00101 + C00024 <=> C00440 + C00010 + C00237
Comment
two-step reaction (see R08433+R02289)
Reaction class
RC00004  C00010_C00024
RC00113  C00101_C00440
RC02963  C00024_C00237
RC02977  C00024_C00440
Enzyme
2.1.1.258       2.3.1.169
Pathway
rn00720  Other carbon fixation pathways
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
Module
M00377  Reductive acetyl-CoA pathway (Wood-Ljungdahl pathway)
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.258
     R10243  Tetrahydrofolate + Acetyl-CoA <=> 5-Methyltetrahydrofolate + CoA + CO
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.169
     R10243  Tetrahydrofolate + Acetyl-CoA <=> 5-Methyltetrahydrofolate + CoA + CO
Overall reaction [br08210.html]
 Carbon fixation
  R10243
Orthology
K00194  acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta [EC:2.1.1.245]
K00197  acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245]
K14138  acetyl-CoA synthase [EC:2.3.1.169]
K15023  5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase [EC:2.1.1.258]
LinkDB

KEGG   RCLASS: RC00113
Entry
RC00113                     RClass                                 
Definition
N1x-N1y:*-C1a:C1y+C8y-C1y+C8y
Reactant pair
C00101_C00440    C01217_C04488    C02673_C04578
C04144_C04489    C06542_C11810    C11809_C15985
C18799_C18802
Related class
Reaction
R00946 R02289 R02573 R02912 R04013 R04347 R04405 R05881
R09096 R09270 R09271 R09365 R10136 R10219 R10243 R10333
R10385 R12138 R12291 R12999
Enzyme
2.1.1.13        2.1.1.14        2.1.1.19        2.1.1.99        
2.1.1.245       2.1.1.258       2.1.1.269       2.1.1.341       
2.1.1.378       2.1.1.384       2.1.1.385       2.1.1.389       
2.1.1.392       2.1.1.-         2.3.1.169       7.2.1.4
Pathway
rn00670  One carbon pool by folate
rn00720  Other carbon fixation pathways
rn00901  Indole alkaloid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
Orthology
K00193  acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit beta [EC:2.3.1.169]
K00194  acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta [EC:2.1.1.245]
K00197  acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245]
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
K00549  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
K00577  tetrahydromethanopterin S-methyltransferase subunit A [EC:7.2.1.4]
K00578  tetrahydromethanopterin S-methyltransferase subunit B [EC:7.2.1.4]
K00579  tetrahydromethanopterin S-methyltransferase subunit C [EC:7.2.1.4]
K00580  tetrahydromethanopterin S-methyltransferase subunit D [EC:7.2.1.4]
K00581  tetrahydromethanopterin S-methyltransferase subunit E [EC:7.2.1.4]
K00582  tetrahydromethanopterin S-methyltransferase subunit F [EC:7.2.1.4]
K00583  tetrahydromethanopterin S-methyltransferase subunit G [EC:7.2.1.4]
K00584  tetrahydromethanopterin S-methyltransferase subunit H [EC:7.2.1.4]
K00599  tRNA N(3)-methylcytidine methyltransferase METTL6 [EC:2.1.1.-]
K14138  acetyl-CoA synthase [EC:2.3.1.169]
K15023  5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase [EC:2.1.1.258]
K15064  syringate O-demethylase [EC:2.1.1.-]
K15066  vanillate/3-O-methylgallate O-demethylase [EC:2.1.1.341]
K17486  dimethylsulfoniopropionate demethylase [EC:2.1.1.269]
K21896  3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase [EC:2.1.1.99]
K24042  methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54]
K25221  [methyl-Co(III) glycine betaine-specific corrinoid protein]---tetrahydrofolate methyltransferase [EC:2.1.1.378]
K25915  [methyl-Co(III) methoxylated-aromatic-compound-specific corrinoid protein]---tetrahydrofolate methyltransferase [EC:2.1.1.385]
K26930  [methyl-Co(III) quaternary-amine-specific corrinoid protein]---tetrahydrofolate methyltransferase [EC:2.1.1.389]
K27779  norajmaline N-methyltransferase [EC:2.1.1.392]

KEGG   RCLASS: RC02977
Entry
RC02977                     RClass                                 
Definition
C1a-C1a:C5a+*-*+N1y:*-*
Reactant pair
C00024_C00440    C00024_C04488    C00024_C18799
Related class
Reaction
R09096 R10219 R10243
Enzyme
2.1.1.258       2.3.1.169
Pathway
rn00720  Other carbon fixation pathways
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
Orthology
K00193  acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit beta [EC:2.3.1.169]
K00194  acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta [EC:2.1.1.245]
K00197  acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245]
K14138  acetyl-CoA synthase [EC:2.3.1.169]
K15023  5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase [EC:2.1.1.258]

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