KEGG   REACTION: R10820
Entry
R10820                      Reaction                               
Name
3-(methylthio)propanoate:CoA ligase (AMP-forming)
Definition
ATP + 3-(Methylthio)propanoate + CoA <=> AMP + Diphosphate + 3-(Methylthio)propanoyl-CoA
Equation
Reaction class
RC00004  C00010_C20870
RC00014  C08276_C20870
Enzyme
Pathway
rn00920  Sulfur metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.44
     R10820  ATP + 3-(Methylthio)propanoate + CoA <=> AMP + Diphosphate + 3-(Methylthio)propanoyl-CoA
Orthology
K20034  3-(methylthio)propionyl---CoA ligase [EC:6.2.1.44]
Other DBs
RHEA: 43055
LinkDB

KEGG   RCLASS: RC00014
Entry
RC00014                     RClass                                 
Definition
C5a-C6a:S2a+*-*+O6a:C1b+O5a-C1b+O6a
Reactant pair
C00025_C18006    C00042_C00091    C00042_C03174
C00083_C00383    C00099_C02335    C00100_C00163
C00120_C01894    C00136_C00246    C00149_C04348
C00154_C00249    C00158_C00566    C00164_C00332
C00219_C02249    C00222_C05989    C00249_C05764
C00249_C17202    C00264_C01656    C00318_C20750
C00356_C03761    C00383_C01209    C00412_C01530
C00489_C00527    C00490_C00531    C00497_C20747
C00510_C00712    C00582_C07086    C00638_C03371
C00638_C20683    C00642_C05338    C00695_C01794
 » show all
Related class
Reaction
Enzyme
2.3.1.85        2.3.1.187       2.3.1.315       2.8.3.1         
2.8.3.2         2.8.3.3         2.8.3.5         2.8.3.6         
2.8.3.8         2.8.3.9         2.8.3.10        2.8.3.11        
2.8.3.13        2.8.3.14        2.8.3.15        2.8.3.18        
2.8.3.20        2.8.3.21        2.8.3.22        2.8.3.23        
2.8.3.24        2.8.3.25        2.8.3.26        2.8.3.-         
3.1.2.2         3.1.2.3         3.1.2.4         3.1.2.5         
3.1.2.11        3.1.2.13        3.1.2.14        3.1.2.21        
3.1.2.22        3.1.2.27        3.1.2.29        3.1.2.30        
3.1.2.31        3.1.2.32        3.1.2.-         3.2.1.-         
4.2.1.155       6.2.1.1         6.2.1.2         6.2.1.3         
6.2.1.4         6.2.1.5         6.2.1.6         6.2.1.7         
6.2.1.9         6.2.1.11        6.2.1.13        6.2.1.14        
6.2.1.15        6.2.1.16        6.2.1.17        6.2.1.18        
6.2.1.19        6.2.1.20        6.2.1.23        6.2.1.24        
6.2.1.26        6.2.1.30        6.2.1.36        6.2.1.38        
6.2.1.39        6.2.1.40        6.2.1.41        6.2.1.44        
6.2.1.47        6.2.1.48        6.2.1.51        6.2.1.56        
6.2.1.76        6.2.1.-
 » show all
Pathway
rn00020  Citrate cycle (TCA cycle)
rn00061  Fatty acid biosynthesis
rn00062  Fatty acid elongation
rn00071  Fatty acid degradation
rn00074  Mycolic acid biosynthesis
rn00120  Primary bile acid biosynthesis
rn00130  Ubiquinone and other terpenoid-quinone biosynthesis
rn00280  Valine, leucine and isoleucine degradation
rn00310  Lysine degradation
rn00333  Prodigiosin biosynthesis
rn00350  Tyrosine metabolism
rn00360  Phenylalanine metabolism
rn00362  Benzoate degradation
rn00405  Phenazine biosynthesis
rn00410  beta-Alanine metabolism
rn00430  Taurine and hypotaurine metabolism
rn00524  Neomycin, kanamycin and gentamicin biosynthesis
rn00592  alpha-Linolenic acid metabolism
rn00627  Aminobenzoate degradation
rn00630  Glyoxylate and dicarboxylate metabolism
rn00640  Propanoate metabolism
rn00642  Ethylbenzene degradation
rn00650  Butanoate metabolism
rn00660  C5-Branched dibasic acid metabolism
rn00680  Methane metabolism
rn00720  Other carbon fixation pathways
rn00780  Biotin metabolism
rn00903  Limonene degradation
rn00907  Pinene, camphor and geraniol degradation
rn00920  Sulfur metabolism
rn00930  Caprolactam degradation
rn00980  Metabolism of xenobiotics by cytochrome P450
rn00984  Steroid degradation
rn00997  Biosynthesis of various other secondary metabolites
rn01040  Biosynthesis of unsaturated fatty acids
rn01059  Biosynthesis of enediyne antibiotics
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
rn01212  Fatty acid metabolism
rn01220  Degradation of aromatic compounds
rn01240  Biosynthesis of cofactors
RModule
RM017  Ring cleavage via Baeyer-Villiger oxidation
RM019  Acyl-CoA conversion via dicarboxylate semialdehyde
Orthology
K00665  fatty acid synthase, animal type [EC:2.3.1.85]
K01026  propionate CoA-transferase [EC:2.8.3.1]
K01027  3-oxoacid CoA-transferase [EC:2.8.3.5]
K01028  3-oxoacid CoA-transferase subunit A [EC:2.8.3.5]
K01029  3-oxoacid CoA-transferase subunit B [EC:2.8.3.5]
K01031  3-oxoadipate CoA-transferase, alpha subunit [EC:2.8.3.6]
K01032  3-oxoadipate CoA-transferase, beta subunit [EC:2.8.3.6]
K01034  acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]
K01035  acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]
K01041  glutaryl-CoA transferase [EC:2.8.3.-]
K01068  acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]
K01071  medium-chain acyl-[acyl-carrier-protein] hydrolase [EC:3.1.2.21]
K01074  palmitoyl-protein thioesterase [EC:3.1.2.22]
K01895  acetyl-CoA synthetase [EC:6.2.1.1]
K01896  medium-chain acyl-CoA synthetase [EC:6.2.1.2]
K01897  long-chain acyl-CoA synthetase [EC:6.2.1.3]
K01899  succinyl-CoA synthetase alpha subunit [EC:6.2.1.4 6.2.1.5]
K01900  succinyl-CoA synthetase beta subunit [EC:6.2.1.4 6.2.1.5]
K01902  succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
K01903  succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
K01905  acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13]
K01906  6-carboxyhexanoate--CoA ligase [EC:6.2.1.14]
K01907  acetoacetyl-CoA synthetase [EC:6.2.1.16]
K01908  propionyl-CoA synthetase [EC:6.2.1.17]
K01909  long-chain-fatty-acid--[acyl-carrier-protein] ligase [EC:6.2.1.20]
K01911  o-succinylbenzoate---CoA ligase [EC:6.2.1.26]
K01912  phenylacetate-CoA ligase [EC:6.2.1.30]
K01913  acetate/butyrate---CoA ligase [EC:6.2.1.1 6.2.1.2]
K02182  carnitine-CoA ligase [EC:6.2.1.48]
K02614  acyl-CoA thioesterase [EC:3.1.2.-]
K05605  3-hydroxyisobutyryl-CoA hydrolase [EC:3.1.2.4]
K05939  acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase / long-chain-fatty-acid--[acyl-carrier-protein] ligase [EC:2.3.1.40 6.2.1.20]
K07543  benzylsuccinate CoA-transferase BbsE subunit [EC:2.8.3.15]
K07544  benzylsuccinate CoA-transferase BbsF subunit [EC:2.8.3.15]
K08298  L-carnitine CoA-transferase [EC:2.8.3.21]
K08692  malate-CoA ligase subunit alpha [EC:6.2.1.9]
K08748  solute carrier family 27 (fatty acid transporter), member 5 [EC:6.2.1.7]
K10526  OPC-8:0 CoA ligase 1 [EC:6.2.1.-]
K10781  fatty acyl-ACP thioesterase B [EC:3.1.2.14 3.1.2.21]
K10782  fatty acyl-ACP thioesterase A [EC:3.1.2.14]
K10804  acyl-CoA thioesterase I [EC:3.1.2.- 3.1.2.2 3.1.1.2 3.1.1.5]
K10805  acyl-CoA thioesterase II [EC:3.1.2.-]
K10806  acyl-CoA thioesterase YciA [EC:3.1.2.-]
K11992  acyl-CoA thioesterase 8 [EC:3.1.2.27]
K12428  fatty acyl-AMP ligase FadD32 [EC:6.2.1.-]
K13559  [BtrI acyl-carrier protein]--L-glutamate ligase [EC:6.2.1.39]
K13776  citronellyl-CoA synthetase [EC:6.2.1.-]
K13929  malonate decarboxylase alpha subunit [EC:2.3.1.187]
K14067  malate-CoA ligase subunit beta [EC:6.2.1.9]
K14451  (3S)-malyl-CoA thioesterase [EC:3.1.2.30]
K14466  4-hydroxybutyrate---CoA ligase (AMP-forming) [EC:6.2.1.40]
K14467  4-hydroxybutyrate---CoA ligase (AMP-forming) [EC:6.2.1.40]
K14469  acrylyl-CoA reductase (NADPH) / 3-hydroxypropionyl-CoA dehydratase / 3-hydroxypropionyl-CoA synthetase [EC:1.3.1.84 4.2.1.116 6.2.1.36]
K14471  succinyl-CoA:(S)-malate CoA-transferase subunit A [EC:2.8.3.22]
K14472  succinyl-CoA:(S)-malate CoA-transferase subunit B [EC:2.8.3.22]
K14747  benzoylacetate-CoA ligase [EC:6.2.1.-]
K14760  o-succinylbenzoate---CoA ligase [EC:6.2.1.26]
K15013  long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3]
K15018  3-hydroxypropionyl-coenzyme A synthetase [EC:6.2.1.36]
K15232  citryl-CoA synthetase large subunit [EC:6.2.1.18]
K15233  citryl-CoA synthetase small subunit
K15569  naphthyl-2-methylsuccinate CoA transferase subunit [EC:2.8.3.-]
K15570  naphthyl-2-methylsuccinate CoA transferase subunit [EC:2.8.3.-]
K15871  bile acid CoA-transferase [EC:2.8.3.25]
K17360  acyl-coenzyme A thioesterase 7 [EC:3.1.2.2]
K18118  succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18]
K18122  4-hydroxybutyrate CoA-transferase [EC:2.8.3.-]
K18288  itaconate CoA-transferase [EC:2.8.3.-]
K18289  itaconate CoA-transferase [EC:2.8.3.- 2.8.3.22]
K18313  succinyl-CoA---D-citramalate CoA-transferase [EC:2.8.3.20]
K18593  4-hydroxybutyrate---CoA ligase (ADP-forming) [EC:6.2.1.56]
K18594  3-hydroxypropionyl-CoA synthetase (ADP-forming) [EC:6.2.1.-]
K18660  malonyl-CoA/methylmalonyl-CoA synthetase [EC:6.2.1.76 6.2.1.-]
K18687  HIP---CoA ligase [EC:6.2.1.41]
K18861  4-hydroxybutyrate---CoA ligase (AMP-forming) [EC:6.2.1.40]
K19280  succinyl-CoA:mesaconate CoA transferase [EC:2.8.3.26]
K19282  bifunctional (S)-malyl-CoA lyase/thioesterase [EC:4.1.3.24 3.1.2.30]
K19709  acetate CoA-transferase [EC:2.8.3.8]
K20034  3-(methylthio)propionyl---CoA ligase [EC:6.2.1.44]
K20257  2-aminobenzoylacetyl-CoA thioesterase [EC:3.1.2.32]
K20882  (R)-2-hydroxy-4-methylpentanoate CoA-transferase [EC:2.8.3.24]
K20985  dihydromonacolin L-[lovastatin nonaketide synthase] thioesterase [EC:3.1.2.31]
K21059  4-hydroxyphenylalkanoate adenylyltransferase [EC:6.2.1.51]
K21107  medium-chain-fatty-acid---[acyl-carrier-protein] ligase [EC:6.2.1.47]
K21182  (S)-beta-tyrosine adenylation enzyme [EC:6.2.1.-]
K21228  (R)-2-aza-beta-tyrosine adenylation enzyme [EC:6.2.1.-]
K21791  thioesterase
K22224  acetate---CoA ligase (ADP-forming) subunit beta [EC:6.2.1.13]
K23756  medium-chain acyl-CoA ligase / lipoate-activating enzyme [EC:6.2.1.2]
K24012  acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
K25774  4-hydroxybutyrate---CoA ligase (AMP-forming) [EC:6.2.1.40]
K26005  sulfoacetate-CoA ligase [EC:6.2.1.-]
K27540  succinyl-CoA:cyclohexane-1-carboxylate CoA transferase [EC:2.3.1.315]

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