KEGG   REACTION: R10827
Entry
R10827                      Reaction                               
Name
very-long-chain (3R)-3-hydroxyacyl-CoA hydro-lyase
Definition
Very-long-chain (3R)-3-hydroxyacyl-CoA <=> Very-long-chain trans-2,3-dehydroacyl-CoA + H2O
Equation
C20878 <=> C20879 + C00001
Comment
Elongation of C16/C18 acyl-CoAs to very-long-chain acyl CoAs.
Reaction class
RC00770  C20878_C20879
Enzyme
4.2.1.134
Pathway
rn00062  Fatty acid elongation
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.134
     R10827  Very-long-chain (3R)-3-hydroxyacyl-CoA <=> Very-long-chain trans-2,3-dehydroacyl-CoA + H2O
Orthology
K10703  very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
Other DBs
RHEA: 45815
LinkDB

KEGG   RCLASS: RC00770
Entry
RC00770                     RClass                                 
Definition
C1b-C2b:*-*:C1c+C5a-C2b+C5a
C1c-C2b:O1a-*:C1b+R-C2b+R
Reactant pair
C00640_C00658    C00658_C01086    C00693_C01271
C01086_C01122    C20878_C20879
Related class
Reaction
R02685 R03224 R09698 R10208 R10827
Enzyme
4.2.1.17        4.2.1.59        4.2.1.74        4.2.1.119       
4.2.1.134       4.2.1.-
Pathway
rn00061  Fatty acid biosynthesis
rn00062  Fatty acid elongation
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K01716  3-hydroxyacyl-[acyl-carrier protein] dehydratase / trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:4.2.1.59 5.3.3.14]
K02372  3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
K07511  enoyl-CoA hydratase [EC:4.2.1.17]
K07515  enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211]
K10703  very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
K12405  (3R)-3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.- 4.2.1.107 4.2.1.119]
K16363  UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase / 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:3.5.1.108 4.2.1.59]
K19658  peroxisomal enoyl-CoA hydratase 2 [EC:4.2.1.119]
K19659  enoyl-CoA hydratase [EC:4.2.1.119]
K22540  3-hydroxyacyl-thioester dehydratase, animal type [EC:4.2.1.-]
K22541  3-hydroxyacyl-thioester dehydratase, fungi type [EC:4.2.1.-]

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