KEGG   REACTION: R10828
Entry
R10828                      Reaction                               
Name
very-long-chain acyl-CoA:NADP+ oxidoreductase
Definition
Very-long-chain acyl-CoA + NADP+ <=> Very-long-chain trans-2,3-dehydroacyl-CoA + NADPH + H+
Equation
C20876 + C00006 <=> C20879 + C00005 + C00080
Comment
Elongation of C16/C18 acyl-CoAs to very-long-chain acyl CoAs.
Reaction class
RC00001  C00005_C00006
RC00120  C20876_C20879
Enzyme
1.3.1.93
Pathway
rn00062  Fatty acid elongation
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.93
     R10828  Very-long-chain acyl-CoA + NADP+ <=> Very-long-chain trans-2,3-dehydroacyl-CoA + NADPH + H+
Orthology
K10258  very-long-chain enoyl-CoA reductase [EC:1.3.1.93]
Other DBs
RHEA: 14476
LinkDB

KEGG   RCLASS: RC00120
Entry
RC00120                     RClass                                 
Definition
C1b-C2b:*-*:C1b+C5a-C2b+C5a
C1b-C2b:*-*:C1b+R-C2b+R
Reactant pair
C00173_C00693    C20675_C20676    C20876_C20879
C22022_C22023
Related class
Reaction
R01178 R01403 R01404 R10828 R12236
Enzyme
1.3.1.9         1.3.1.10        1.3.1.39        1.3.1.93        
1.3.1.104       1.3.1.118       1.3.1.-         1.3.8.1
Pathway
rn00061  Fatty acid biosynthesis
rn00062  Fatty acid elongation
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K00208  enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
K00209  enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase (NAD+) [EC:1.3.1.9 1.3.1.44]
K00248  butyryl-CoA dehydrogenase [EC:1.3.8.1]
K00665  fatty acid synthase, animal type [EC:2.3.1.85]
K00668  fatty acid synthase subunit beta, fungi type [EC:2.3.1.86]
K02371  enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9]
K07512  mitochondrial enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase [EC:1.3.1.- 1.3.1.38]
K10258  very-long-chain enoyl-CoA reductase [EC:1.3.1.93]
K10780  enoyl-[acyl-carrier protein] reductase III [EC:1.3.1.104]

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