KEGG   REACTION: R11126
Entry
R11126                      Reaction                               
Name
monacolin-J-acid:(S)-2-methylbutanoyl-[acp] (S)-2-methylbutanoyltransferase
Definition
Monacolin J acid + (S)-2-Methylbutanoyl-[acp] <=> Lovastatin acid + Acyl-carrier protein
Equation
Comment
Acy-carrier protein is acp domain of LOVF [KO:K20984].
Reaction class
RC00055  C20854_C21130
Enzyme
Pathway
rn00997  Biosynthesis of various other secondary metabolites
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00893  Lovastatin biosynthesis, malonyl-CoA => lovastatin acid
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.238
     R11126  Monacolin J acid + (S)-2-Methylbutanoyl-[acp] <=> Lovastatin acid + Acyl-carrier protein
Orthology
K20983  monacolin J acid methylbutanoate transferase [EC:2.3.1.238]
Other DBs
RHEA: 43067
LinkDB

KEGG   RCLASS: RC00055
Entry
RC00055                     RClass                                 
Definition
O1a-O7a:*-C7a:C1y-C1y
Reactant pair
C00031_C01158    C00031_C01175    C00031_C04164
C00031_C04197    C00031_C15970    C00031_C17759
C00043_C04738    C00043_C22418    C00066_C02056
C00066_C03880    C00066_C05156    C00137_C03868
C00187_C02530    C00191_C05787    C00191_C20383
C00221_C16827    C00270_C04015    C00296_C00852
C00296_C02572    C00296_C12208    C00301_C20658
C00301_C22131    C00370_C01958    C00370_C22215
C00400_C09870    C00477_C02681    C00493_C02947
C00493_C10434    C00553_C16825    C00729_C01479
 » show all
Related class
Reaction
Enzyme
1.2.1.70        1.-.-.-         2.1.3.12        2.1.3.-         
2.3.1.26        2.3.1.43        2.3.1.44        2.3.1.69        
2.3.1.72        2.3.1.73        2.3.1.77        2.3.1.90        
2.3.1.91        2.3.1.92        2.3.1.93        2.3.1.98        
2.3.1.99        2.3.1.103       2.3.1.107       2.3.1.129       
2.3.1.133       2.3.1.139       2.3.1.143       2.3.1.150       
2.3.1.152       2.3.1.162       2.3.1.163       2.3.1.166       
2.3.1.167       2.3.1.185       2.3.1.186       2.3.1.205       
2.3.1.213       2.3.1.214       2.3.1.238       2.3.1.278       
2.3.1.279       2.3.1.285       2.3.1.288       2.3.1.320       
2.3.1.-         2.3.2.3         2.3.2.6         2.3.2.8         
2.3.2.10        2.3.2.11        2.3.2.12        2.3.2.16        
2.3.2.17        2.3.2.18        2.3.2.20        2.3.2.21        
2.3.2.22        2.3.2.-         3.1.1.1         3.1.1.10        
3.1.1.13        3.1.1.29        3.1.1.42        3.1.1.51        
3.1.1.53        3.1.1.80        3.1.1.84        3.1.1.93        
3.1.1.106       3.1.1.-         3.2.1.31        3.2.1.175       
3.-.-.-         6.1.1.1         6.1.1.2         6.1.1.3         
6.1.1.4         6.1.1.5         6.1.1.6         6.1.1.7         
6.1.1.9         6.1.1.10        6.1.1.11        6.1.1.12        
6.1.1.14        6.1.1.15        6.1.1.16        6.1.1.17        
6.1.1.18        6.1.1.19        6.1.1.20        6.1.1.21        
6.1.1.22        6.1.1.23        6.1.1.24        6.1.1.26        
6.1.1.27
 » show all
Pathway
rn00100  Steroid biosynthesis
rn00401  Novobiocin biosynthesis
rn00540  Lipopolysaccharide biosynthesis
rn00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
rn00901  Indole alkaloid biosynthesis
rn00904  Diterpenoid biosynthesis
rn00941  Flavonoid biosynthesis
rn00942  Anthocyanin biosynthesis
rn00950  Isoquinoline alkaloid biosynthesis
rn00960  Tropane, piperidine and pyridine alkaloid biosynthesis
rn00965  Betalain biosynthesis
rn00997  Biosynthesis of various other secondary metabolites
rn01051  Biosynthesis of ansamycins
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K00637  sterol O-acyltransferase [EC:2.3.1.26]
K00650  lecithin-cholesterol acyltransferase [EC:2.3.1.43]
K00677  UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]
K00684  leucyl/phenylalanyl-tRNA---protein transferase [EC:2.3.2.6]
K00685  arginyl-tRNA---protein transferase [EC:2.3.2.8]
K01044  carboxylesterase 1 [EC:3.1.1.1]
K01052  lysosomal acid lipase/cholesteryl ester hydrolase [EC:3.1.1.13]
K01195  beta-glucuronidase [EC:3.2.1.31]
K01866  tyrosyl-tRNA synthetase [EC:6.1.1.1]
K01867  tryptophanyl-tRNA synthetase [EC:6.1.1.2]
K01868  threonyl-tRNA synthetase [EC:6.1.1.3]
K01869  leucyl-tRNA synthetase [EC:6.1.1.4]
K01870  isoleucyl-tRNA synthetase [EC:6.1.1.5]
K01872  alanyl-tRNA synthetase [EC:6.1.1.7]
K01873  valyl-tRNA synthetase [EC:6.1.1.9]
K01874  methionyl-tRNA synthetase [EC:6.1.1.10]
K01875  seryl-tRNA synthetase [EC:6.1.1.11]
K01876  aspartyl-tRNA synthetase [EC:6.1.1.12]
K01878  glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
K01879  glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
K01880  glycyl-tRNA synthetase [EC:6.1.1.14]
K01881  prolyl-tRNA synthetase [EC:6.1.1.15]
K01883  cysteinyl-tRNA synthetase [EC:6.1.1.16]
K01884  cysteinyl-tRNA synthetase, unknown class [EC:6.1.1.16]
K01885  glutamyl-tRNA synthetase [EC:6.1.1.17]
K01886  glutaminyl-tRNA synthetase [EC:6.1.1.18]
K01887  arginyl-tRNA synthetase [EC:6.1.1.19]
K01889  phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
K01890  phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
K01892  histidyl-tRNA synthetase [EC:6.1.1.21]
K01893  asparaginyl-tRNA synthetase [EC:6.1.1.22]
K02492  glutamyl-tRNA reductase [EC:1.2.1.70]
K04566  lysyl-tRNA synthetase, class I [EC:6.1.1.6]
K04567  lysyl-tRNA synthetase, class II [EC:6.1.1.6]
K05294  GPI inositol-deacylase [EC:3.-.-.-]
K05363  serine/alanine adding enzyme [EC:2.3.2.10]
K07587  O-phosphoseryl-tRNA synthetase [EC:6.1.1.27]
K09698  nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]
K09756  serine carboxypeptidase-like 19 [EC:3.4.16.- 2.3.1.91]
K09757  serine carboxypeptidase-like 8 [EC:3.4.16.- 2.3.1.92]
K09759  nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
K09953  lipid A 3-O-deacylase [EC:3.1.1.-]
K11627  pyrrolysyl-tRNA synthetase [EC:6.1.1.26]
K11693  peptidoglycan pentaglycine glycine transferase (the first glycine) [EC:2.3.2.16]
K11694  peptidoglycan pentaglycine glycine transferase (the second and third glycine) [EC:2.3.2.17]
K11695  peptidoglycan pentaglycine glycine transferase (the fourth and fifth glycine) [EC:2.3.2.18]
K12298  bile salt-stimulated lipase [EC:3.1.1.3 3.1.1.13]
K12554  alanine adding enzyme [EC:2.3.2.-]
K12698  deacetylvindoline O-acetyltransferase [EC:2.3.1.107]
K12713  decarbamoylnovobiocin carbamoyltransferase [EC:2.1.3.12]
K12722  clorobiocin/coumermycin A biosynthesis protein CloN6/CouN6
K12724  clorobiocin/coumermycin A biosynthesis protein CloN7/CouN7
K12923  taxadien-5alpha-ol O-acetyltransferase [EC:2.3.1.162]
K12925  2alpha-hydroxytaxane 2-O-benzoyltransferase [EC:2.3.1.166]
K12926  10-deacetylbaccatin III 10-O-acetyltransferase [EC:2.3.1.167]
K12932  anthocyanidin 3-O-glucoside-3'',6''-O-dimalonyltransferase [EC:2.3.1.-]
K12935  anthocyanin 5-O-glucoside-4'''-O-malonyltransferase [EC:2.3.1.214]
K12976  lipid A 3-O-deacylase [EC:3.1.1.-]
K13065  shikimate O-hydroxycinnamoyltransferase [EC:2.3.1.133]
K13393  salutaridinol 7-O-acetyltransferase [EC:2.3.1.150]
K13610  13-hydroxylupinine O-tigloyltransferase [EC:2.3.1.93]
K14163  bifunctional glutamyl/prolyl-tRNA synthetase [EC:6.1.1.17 6.1.1.15]
K14164  glycyl-tRNA synthetase [EC:6.1.1.14]
K14674  TAG lipase / steryl ester hydrolase / phospholipase A2 / LPA acyltransferase [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
K15748  beta-D-glucopyranosyl abscisate beta-glucosidase [EC:3.2.1.175]
K15999  mycarose O-acyltransferase
K16035  7-O-carbamoyltransferase [EC:2.1.3.-]
K16036  3-O-acyltransferase
K18368  caffeoylshikimate esterase [EC:3.1.1.-]
K19184  fumigaclavine B O-acetyltransferase [EC:2.3.1.205]
K20983  monacolin J acid methylbutanoate transferase [EC:2.3.1.238]
K21026  acetylajmaline esterase [EC:3.1.1.80]
K21419  arginyl-tRNA---protein transferase [EC:2.3.2.8]
K22095  (13S,14R)-1,13-dihydroxy-N-methylcandine 13-O-acetyltransferase [EC:2.3.1.285]
K22503  aspartyl-tRNA synthetase [EC:6.1.1.12]
K22795  2-O-sulfo trehalose long-chain-acyltransferase [EC:2.3.1.288]
K23156  mycolipenoyl-CoA---2-(long-chain-fatty acyl)-trehalose mycolipenoyltransferase / long-chain-acyl-CoA---trehalose acyltransferase [EC:2.3.1.278 2.3.1.279]
K23518  O-acetyl-ADP-ribose deacetylase [EC:3.1.1.106]
K24278  ergosteryl-3beta-O-L-aspartate synthase [EC:6.1.1.12 2.3.2.37]
K25583  littorine synthase [EC:2.3.1.-]
K27849  taxoid C-13 O-(3-amino-3-phenylpropanoyl)transferase [EC:2.3.1.320]

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