KEGG   REACTION: R11175
Entry
R11175                      Reaction                               
Name
(S)-nicotine:cytochrome c oxidoreductase (N-methylmimosine-forming)
Definition
Nicotine + 2 Ferricytochrome c <=> N-Methylmyosmine + 2 Ferrocytochrome c + 2 H+
Equation
C00745 + 2 C00125 <=> C21154 + 2 C00126 + 2 C00080
Comment
first step of two-step reaction (see R11177, R11175+R11176)
Enzyme
1.4.2.2
Pathway
rn00760  Nicotinate and nicotinamide metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Module
M00811  Nicotine degradation, pyrrolidine pathway, nicotine => succinate semialdehyde
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.4  Acting on the CH-NH2 group of donors
   1.4.2  With a cytochrome as acceptor
    1.4.2.2
     R11175  Nicotine + 2 Ferricytochrome c <=> N-Methylmyosmine + 2 Ferrocytochrome c + 2 H+
Orthology
K20169  nicotine dehydrogenase [EC:1.4.2.2]
Reference
1  [PMID:24204321]
  Authors
Tang H, Wang L, Wang W, Yu H, Zhang K, Yao Y, Xu P
  Title
Systematic unraveling of the unsolved pathway of nicotine degradation in Pseudomonas.
  Journal
PLoS Genet 9:e1003923 (2013)
DOI:10.1371/journal.pgen.1003923
Other DBs
RHEA: 73658
LinkDB

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