KEGG   REACTION: R12058
Entry
R12058                      Reaction                               
Name
ent-isokaurene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (ent-isokaurene-2beta,3beta-diol forming)
Definition
ent-Isokaurene + 2 Oxygen + 2 [Reduced NADPH---hemoprotein reductase] <=> ent-2alpha,3alpha-Dihydroxyisokaurene + 2 [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Equation
C20145 + 2 C00007 + 2 C03024 <=> C21831 + 2 C03161 + 2 C00001
Comment
two-step reaction (see R09861+R11978)
Enzyme
1.14.14.76
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.76
     R12058  ent-Isokaurene + 2 Oxygen + 2 [Reduced NADPH---hemoprotein reductase] <=> ent-2alpha,3alpha-Dihydroxyisokaurene + 2 [Oxidized NADPH---hemoprotein reductase] + 2 H2O
LinkDB

KEGG   REACTION: R09861
Entry
R09861                      Reaction                               
Name
ent-isokaurene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase
Definition
ent-Isokaurene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> ent-2alpha-Hydroxyisokaurene + H2O + [Oxidized NADPH---hemoprotein reductase]
Equation
C20145 + C00007 + C03024 <=> C20146 + C00001 + C03161
Comment
the first step of two-step reaction (see R12058, R09861+R11978)
Reaction class
RC00478  C20145_C20146
Enzyme
1.14.14.76
Pathway
rn00904  Diterpenoid biosynthesis
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.76
     R09861  ent-Isokaurene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> ent-2alpha-Hydroxyisokaurene + H2O + [Oxidized NADPH---hemoprotein reductase]
Orthology
K16083  ent-isokaurene hydroxylase [EC:1.14.14.76]
Other DBs
RHEA: 31950
LinkDB

KEGG   REACTION: R11978
Entry
R11978                      Reaction                               
Name
ent-isokaurene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase
Definition
ent-2alpha-Hydroxyisokaurene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> ent-2alpha,3alpha-Dihydroxyisokaurene + H2O + [Oxidized NADPH---hemoprotein reductase]
Equation
C20146 + C00007 + C03024 <=> C21831 + C00001 + C03161
Comment
the second step of two-step reaction (see R12058, R09861+R11978)
Reaction class
RC01993  C20146_C21831
Enzyme
1.14.14.76
Pathway
rn00904  Diterpenoid biosynthesis
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.76
     R11978  ent-2alpha-Hydroxyisokaurene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> ent-2alpha,3alpha-Dihydroxyisokaurene + H2O + [Oxidized NADPH---hemoprotein reductase]
Orthology
K16083  ent-isokaurene hydroxylase [EC:1.14.14.76]
LinkDB

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