KEGG   REACTION: R12498
Entry
R12498                      Reaction                               
Definition
2-Hydroxyethylphosphonate + CTP <=> Cytidine 5'-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} + Diphosphate
Equation
Comment
cytidylyltransferase
Reaction class
RC00002  C06451_C22216
Enzyme
Pathway
rn00998  Biosynthesis of various antibiotics
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00903  Fosfomycin biosynthesis, phosphoenolpyruvate => fosfomycin
Orthology
K23999  phosphoenolpyruvate phosphomutase / 2-hydroxyethylphosphonate cytidylyltransferase [EC:5.4.2.9 2.7.7.104]
Reference
1  [PMID:29969250]
  Authors
McLaughlin MI, van der Donk WA.
  Title
Stereospecific Radical-Mediated B12-Dependent Methyl Transfer by the Fosfomycin Biosynthesis Enzyme Fom3.
  Journal
Biochemistry 57:4967-4971 (2018)
DOI:10.1021/acs.biochem.8b00616
Other DBs
RHEA: 63423
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