KEGG REACTION: R13219

REACTION: R13219

Entry

R13219                      Reaction

Name

androstan-3alpha,17beta-diol:NADP+ 17-oxidoreductase

Definition

Androsterone + NADPH + H+ <=> Androstan-3alpha,17beta-diol + NADP+

Equation

C00523 + C00005 + C00080 <=> C03852 + C00006

Reaction class

RC00127

C00523_C03852

Enzyme

1.1.1.51 1.1.1.64

Pathway

rn00140

Steroid hormone biosynthesis

rn01100

Metabolic pathways

Module

M00977

C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone

Brite

Enzymatic reactions [BR:br08201]
1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.51
     R13219  Androsterone + NADPH + H+ <=> Androstan-3alpha,17beta-diol + NADP+
    1.1.1.64
     R13219  Androsterone + NADPH + H+ <=> Androstan-3alpha,17beta-diol + NADP+

Orthology

K04119

aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]

K10207

testosterone 17beta-dehydrogenase (NADP+) [EC:1.1.1.64]

LinkDB

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