Anas acuta (northern pintail): 137857592 Help Entry 137857592         CDS       T11380                                  Symbol RYR3 Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism aacu  Anas acuta (northern pintail) Pathway aacu04020   Calcium signaling pathway aacu04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:aacu00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     137857592 (RYR3)    04020 Calcium signaling pathway     137857592 (RYR3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:aacu04040]     137857592 (RYR3) Ion channels [BR:aacu04040]  Voltage-gated cation channels   Ryanodine receptor    137857592 (RYR3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Other DBs NCBI-GeneID:  137857592 NCBI-ProteinID:  XP_068540378 LinkDB All DBs Position 5:complement(39221852..39444248) Genome browser AA seq 4873 aa AA seqDB search MAEGGEGGEDEIQFLRTDDEVVLQCVASVHKEQRKFCLAAEGLGNRLCFLEPTSEAKYVP PDLCICNFVLEQSLSVRALQEMLANTGDNAGEGAAQGGHRTLLYGHAILLRHSFSEMYLT CLTSSRSQTDKLAFDVGLRENAAGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERY LHLSMSNGSIQVDASFMQTLWNVHPTCSGSNITEGYLLGGHVVRFFHGHDECLTIPSTDQ NDSQQKKVLYETGGAGVRARSLWRVEPLRISWSGSNIKWGQPFRLRHITTGMYLALNDDE GLVMLDREKSDTTSSAFCFRASKELKEKQDSTLKRDIDGMGVPEIKYGDSVCFVQHVASA LWLTYKAQDAKSARLGPLKRKVILHQEGHMDDGLTLQRCQHEESQAARIIRNTTSLFSQF IRYGNNRTLSPIALPVEEMAQTLQDLITYFQPPEEDLEHEDKQSKLRSLKNRQNLFKEEG MLALVLNCIDRLNDYNSAAHFAEIAREENGTTWKEILNLLYKLLAALIRGNRNNCTQFSS NLDWLISKLDRLESSSGILEVLHCILIESPEALNIIAEEHIKSIISLLDKHGRNYKVLDV LCSLCVCNGVAVRANQNLICDNLLPRRDLLLQTRLINDVTSIRPNIFLGVAEGSAQYKKW YFELIIDQVDPFLTAEPTHLRVGWASTSGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLW SGRVPRAVASVNQHLLSSDDVVSCCLDLGVPSISFRINGQPVQGMFENFCTEGFFFPVVS LSAGVKARFLLGGRHGEFKFLPPAGYAPCYEALLPKEKMKLEPVKEYKRDSDGVRDLLGT TQFLSQASFIPCPIDTSQIALPFHLEKIRDKLAENIHELWGMNKIELGWTYGKIRDDNKR HHPCLVEFSKLPETEKNYNLQMSTETLKTLLALGCHIVHANPAAEEDLKKVKLPKNYMMS NGYKPAPLDLSEVKLLPSQEFLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNKRNPRLV PYALLDERTKKSNRDSLREAVRTFAGYGYSVEPPDQEIADQTTEKVSIDKIRFFRVEQSY AVKSGKWYFEFEAVTGGDMRVGWARPGCRPDIELGADDQAFVFEGSKGQRWHQGSGFFGR SWQPGDVVGCMINLDDKSIIFTLNGELLITSKGSELAFADFGIESGFVPICALGLSQIGR MNLGMDASTFKYYTMCGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKNHPHIEIWRID GTIESPPRLKVTHKTFGTQNSNSDMIYCRLSMPIEFRSSFNFGMGVENASSDIFQKRKHS QEISVPSTTYFYSLRIFAGQDPSCVWVGWVTPDYHFYSENFDLNKNCTVTVTLGDERGRV HESVKRSNCYMVWGGDITSNSQRSGRSNVDLEIGCFVDLATGMLSFTANGKELGTCYQVE PNTKLFPATFVQPTSTNLVQFELGKLKNTMPLSAAIFKSEERNPIPQCPPRLDVQTITPV LWSRMPNSFLKVETERVSERHGWVVQCLEPLQMMALHIPEENRCVDILELCEQEDLMKFH YHTLKLYSSVCALGNTRVAYALCSHVDVSQLFYTIDNQYLPGLLRSGFYDLLISIHLEHA KQAKLMMNNEFIIPVTEETRTIRLYPDETKKHGLPGVGLSTCLKPSFHFSTPCFIVTSEE HQTSSPEIPLDTLKSKAISMLTEAVQCSGTHIRDPVGGHIAFQFVPVLKLIATLLIMGVF DDDDVKQVLILIDPNVFGDHKEETEEGTEKEEVTQVEEKAVEAGEKAIKETKAPTTGLLQ TRLPESVKLQMCHLLNYFCDCELQHRVEAIVSFADRYVSKLQYNQKYRYNELMQALNMSA ALTAKKTKEFRSPPQEQINMLLNFQLGEDCPCPEEIRDELYDFHDDLLIHCGIPLEEEEE EEEDSTLTGKLRSLIYKIKGPPKAEKVEPREEEEKSPTTLKELISQTMVRWSQEDQIQDP ELVRIMYTLLRRQYDSIGELLQALRKAYTISAASVKDTINLLAALGQIRSLLSVRMGKEE ELLMINGLGDIMNNKVFYQHPNLMRVLGMHETVMDVMVNVLGGDKSQQIAFPKMVASCCR FLCYFCRISRQNQKAMFEHLSYLLENSSVGLAFPSMRGSTPLDVAAASVMDNNELALALE EPDLDKVVTYLAGCGLQSCPVLLAKGYPDIGWNPIEGERYLSFLRFAVFVNSESVEENAS VVVKLLIRRPECFGPDLRGEGGNGLLAAMQEAIRISENPSRDLPSQGYKREGDEEEEEEE IVHMGNAIMSFYSALIDLLGRCAPEMHLIQSGKGEAIRIRSILRSLVPTEDLVGIISIPL KLSTVNKDGTVNEPDMSANFCPDHKAPMVLFLDRVYGIKDQTFLLHLLEVGFLPDLRASA SLDTVSLSTTEAALALNRYICSAVFPLLKRCAPLFSGTEHHASLVDSMLHTIYRLSKGRS LTKAQRDTIEECLLAICHHLRPSMLQQLLRRLVFDVPLLNEYCKMPLKLLTNHYEQCWKY YCLPSGMGSYGIAAEEELHLTEKLFWGIFDSLSHKFLSLLQKYDPELFRMALPCLSAIAG ALPPDYLDTRIRSTLEKQTSVDPEGNFDPKPVSTANLVLPEKLEYIVSKYAEHSHDKWAF DKTNNGWKYGVSLDENTKTHPLIRPFKTLTEKEKEIYRWPARESLKTMLAMGWSLERTKE GGETILHQRENEKLRSISQSSQGNGYSPAPLDLSNVVLSRELQGMVEVMAENYHNIWAKK KKMELESKGGGSHPLLVPYDTLTAKEKSRDREKAQELFKFLQVNGIIISRGLNDMDLDAS SMEKRFAFKFLKKILKYVDSAQEFIAHLEAIVTSGKTEKSPHDQEIKFFAKVLLPLVDQY FTNHCLYFLSSPTKTLSSSGYASNKEKEMVASLFCKLAALVRHRISIFGSDSTTMVNCLH ILAQSLDTRTVMKSGSELVKAGLRAFFENAAEDLEKTSENLKLGKFTHSRTQIKGVSQNI NYTTVALLPVLTSIFEHISQYQFGVDLLLGDVQVSCYRILCSLYSLGTGKNIYVERQRPA LGECLASLAAAIPVAFLEPSLNHYNPLSVFNTKSARERAILGMPDTVEEMCPEIPQLDGL IKEINDLAESGARYTEMPHVIEVILPMLCNYLSYWWERGSESVPESAGPFCTMITSEHLS IILGNILKIINNNLGIDEASWMKRIAVYAQPIISKARPDLLKTHFIPTLEKLKKKAIKIV MEEEQLKADSKTDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRANWLKKPDADSDE LFRMVAEVFILWCKSHNFKREEQNFVIQNEINNLAFLTGDTKSKMSKSGGQDQERKKSKR RGDLYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKTRYSHRDTDEEVKEHLRNNLH LQEKSDDPAVKWQLNLYKDILKNDEPSDPEKNVERVQRISAALYHLEQVEQPLRSKKAVW HKLLSKQRKRAVVACFRMAPLYNLPRHKISNFFLSTFQRVWLEKVHEKTQYDRLILKLTT PPKKDEEEEEDTEKKQPDPLHQIILYFSRNALTERSKLEDDPLYIAYSAMMAKSCQEEEE EEEEEKEKTFEEKEMEKQRTLYQQARLHDRGAAEMVLQMISASKGHTGPMVVETLKLGIA ILNGGNTIVQQKMLDYLKEKKDAGFFQSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEG TLIVRERGEKVLQHDEFTRDLFRFLQLLCEGHNNDFQNYLRTQMGNTTTVNIIISTVDYL LRLQESISDFYWYYSGKDVIDESGQRNFSKALAVTKQIFNSLTEYIQGPCIGNQQSLAHS RLWDAVVGFLHVFANMQMKLSQDSAQIELLKELLDLLKDMVVMLLSLLEGNVVNGTIGKQ MVDTLVESSSNVELILKFFDMFLKLKDLTNSDAFKEHDPDGKGIISKKEFQKSMEAQKQY IQSEIEFLLSCAEADENDMFNYLDFVERFHEPAKDIGFNVAVLLTNLSEHMPNDSRLQSL LEPAESVLNYFEPYLGRIEIMGGAKKIERVYFEISESSRMQWEKPQVKESKRQFIFDVVN EGGEQEKMELFVNFCEDTIFEMQLASQISETDSAERPEEEEEEESCYVVDIGDDEEEEKS LESPSAFAMACAAVKKNVTNFFKMVTVKNLRKQYRKVRKMTVKEMVKVFFSFFWILFVGM FQLFFTIVWGIFQILWSTVFGGGLVEGAKNIKVTKILGDMPDPTQFGIHDDVTEAEKAEG AEHGIRAELVQFVKGEKAETDIISDIFGIPTKKEGGSKHGHDAGLGDIAEMLGSDIQSSL ENTVRKKKGLQLSEIAKEAEAERKVEAEKADMEDGEKEDRAKEVQSEQLEEGKVKKKKRR HGQKIEKPEAVMANFFKALEIYQTKMLHYLARNFYNLRFLALFVAFAINFILLFYKVTEE PLDEVEEDSNLWNTFDEEEEEEGMVFFVLEESTGYMAPALRALAVIHTIISFVCVIGYYC LKVPLVVFKREKEVARKLEFDGLYITEQPSEDDIKGQWDRLVINTPSFPNNYWDKFVKRK VINKYGDLYGAERIAELLGLDKNALDFSPVEESEPEEASLLSWLSSIDTKYHIWKLGVVF TDNSFLYLAWYTTMSILGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLL AVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDP AGDPYEMYRIVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVREDMETKCFICGIG NDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESFVWKMYQERCWDFFPA GDCFRKQYEDQLG NT seq 14622 nt NT seq  +upstreamnt  +downstreamnt atggctgaagggggtgaaggaggggaagatgaaatacagttcctacgaactgatgacgaa gtagtacttcagtgtgttgccagcgttcacaaagaacaaaggaagttttgcttggcagct gagggacttgggaatcgcctgtgctttttggaaccaacatcagaagctaaatatgttcct ccggacctttgcatctgtaattttgtacttgaacagtccctgtctgtcagagcccttcaa gaaatgctggccaacacaggggataatgctggtgaaggggcagctcaaggtggtcacaga accctgctatatggtcatgctatactacttcgacattcgttcagtgaaatgtatttgact tgtttaacgtcatcaagatcccagacagataaacttgcatttgatgtgggactgcgagaa aatgcagcaggtgaagcatgctggtggacaatacaccctgcatctaaacaaaggtcagaa ggagaaaaagttcgaataggtgatgatcttatcctggtcagtgtgtcctctgaaagatac ctgcatctttccatgtcaaatggaagtattcaggtggatgcctcctttatgcagacgctt tggaatgtacatcctacatgctcaggaagcaatattacagaagggtatcttcttggtggg catgtagtacgttttttccatggccatgatgagtgtttgacaattccatctacagatcag aatgattcacagcaaaagaaagtactttatgaaactggaggagctggagttcgagcaagg tctttgtggagagtagaaccacttcgaataagttggagtggaagtaacatcaaatgggga caacctttccgtcttcgacatattacaacaggaatgtacttggctctgaatgatgatgaa ggacttgtaatgttagacagagaaaagtcagacacaacatcttctgctttctgttttaga gcatcaaaggagctaaaagaaaaacaggattccactcttaaacgtgatattgatggaatg ggagtcccagaaataaagtatggtgattcagtctgttttgttcaacatgtggccagtgct ttatggttgacttataaagcacaggatgctaaatcagcacgtttaggtcccttaaaaaga aaggttatactgcaccaagaaggccatatggatgatggtctaaccttacaaagatgtcaa catgaagaatcccaggctgctcgaatcattcgcaatactacaagcttattcagccagttt ataaggtatggaaacaacagaacactatcacccatcgccctgcctgttgaggagatggct cagactctgcaagacctgattacttacttccagcctcccgaagaagacctggaacatgag gataaacaaagcaagcttcgatcactgaaaaacagacagaatctattcaaagaagagggc atgctggcactagttttgaattgcattgatcgtttaaatgactacaacagtgcagctcat tttgcagaaattgcaagagaagaaaatggtaccacatggaaagaaattttaaatcttctt tacaaattgttagctgccctcattcgtggcaacagaaacaattgtactcaattttccagt aaccttgattggctaataagtaaattggacagattagaatcttcctcaggtattttggaa gtgttgcactgcatcttgattgaaagcccagaagctttaaatataatagctgaggagcat ataaaatctattatttcattgttggataaacatgggcgcaattacaaggttctcgatgtg ctttgctctctctgtgtctgtaatggagttgcggttcgtgccaatcaaaatttgatctgt gacaatctattgcctagaagagacttactcttgcaaacacgtttgattaatgatgtgaca agcataaggccgaacatatttctgggtgttgctgagggctctgcacaatacaagaagtgg tactttgaattaataattgatcaggttgatccattcttgacggcagaacccacccattta cgagttggatgggcctctacttcaggttatgctccctatcctggaggaggagaaggatgg gggggcaatggtgttggggatgacctatactcgtacggttttgatggcctccatctgtgg tctggtcgagtacccagggctgtagcatctgtcaatcaacatttgttgtcatctgatgat gtggttagctgctgcttggatttaggcgtacccagcatttcattccgcattaatgggcag cctgtacaaggaatgtttgagaacttctgtactgaagggtttttcttccctgttgtaagc ttatcagcaggtgtaaaagctcgtttcttattgggtggacgtcacggagagtttaaattt ctacctcctgctggctatgctccctgctatgaagccttgcttccaaaagagaagatgaaa ctggaaccagtgaaagaatacaagagagattctgatggagtgagggatttgctgggtaca acacaattcctctcccaagcttcctttatcccttgtcctatagacaccagtcagattgct cttccttttcatcttgaaaagatcagggacaaactagctgaaaatatccatgaactgtgg ggaatgaataaaatagaactgggctggacatatggcaagatacgggatgataataaaagg catcacccttgtcttgtagaattctcaaaattacccgagacagagaagaattataatctg caaatgtcaactgaaactctcaaaacccttttggcccttgggtgtcacattgttcatgct aatccagcagcagaggaagatcttaaaaaagtcaagcttcctaaaaattacatgatgtca aatggatataaacctgcccctcttgatctttctgaagtgaaattgttaccttctcaagaa ttcctagttgacaaactagcagaaaatgcacataatgtctgggcaaaagacagaataaag caaggatggacctatggcattcagcaggatctaaagaacaaacgtaatcctcggctagtg ccatatgcattattagatgaacgtactaaaaaatcgaacagagatagcctccgtgaagct gttagaacatttgcaggctatggttatagtgttgagccacctgatcaagaaatagctgat caaacaacggaaaaagtcagcattgacaagatacgttttttcagagtcgaacagtcttat gcagtgaagtctggaaagtggtactttgaatttgaagctgtgacaggtggagacatgcgt gttggctgggccaggccaggctgtagacctgatatagaactgggagctgatgaccaagca tttgtttttgaaggaagcaaaggccaacgttggcatcaaggcagtggattctttggacga agttggcaaccaggagatgtggttggttgcatgataaacttggatgacaaatccattatc tttactttgaatggagaattgcttataaccagtaaaggttcagaacttgcatttgctgac tttggaatagaaagtggttttgttccaatttgcgcactgggtctgtctcagattggacgt atgaaccttggaatggatgccagtacattcaagtattatacaatgtgtggccttcaagaa ggttttgaaccttttgcagtaaatatgaaccgagatgttgctatgtggttcagtaaacgc ttaccaacatttgtcaatgtgccaaaaaatcatcctcacatagagatatggagaattgat ggaaccattgagagtccacctcggttaaaagttactcacaaaacgtttggcacacagaac agcaattcagacatgatatattgtcgtttgagtatgcctattgagttccgttcatcattc aactttggcatgggtgtggaaaatgcctcatctgatattttccaaaaacgaaaacacagc caagaaatttctgttccttctactacgtatttttattcgttgcggatatttgctgggcaa gacccatcctgtgtctgggttggctgggtaacaccagactatcatttttacagtgagaat tttgacctaaataaaaattgtacagtgacggttactttaggtgatgagagaggcagggtt catgaaagtgtgaagcgcagtaattgctatatggtttggggaggagatataacttctaat tcccagagatcaggtcgtagcaatgttgatttagaaattggatgctttgttgacctagct actggaatgttgtcattcacagccaatggaaaagagcttggcacttgttatcaggttgaa cccaacacaaaactttttccagcaacttttgtacagcctacaagcactaacttggttcag tttgaacttggtaaattaaagaataccatgcctttatcagcagcaatttttaaaagtgag gaaagaaatcctattcctcagtgcccccctcgccttgatgtgcaaacaattacacctgtt ttatggagcaggatgcctaacagctttctcaaagtggaaactgagcgtgtcagtgaacgt catggatgggttgtgcagtgtttggaacctctgcagatgatggcacttcatatcccagag gaaaacagatgtgtcgatattttggaactatgtgaacaagaagatttgatgaagtttcac tatcacactttaaaactctatagctcagtttgtgctctaggtaacactagagttgcttat gcactttgtagccatgtggatgtatctcagttattttacacaatagataatcaatattta cctggactcctacgttctggattctatgacttgttgattagtatacatttggagcatgcc aagcaagccaagctcatgatgaacaatgaatttatcattccagttacagaggaaactcga actattagattatatcctgatgaaacaaagaagcatggtttacctggagtagggcttagc acttgtctgaaaccaagctttcatttttctactccttgctttattgtgaccagtgaagaa catcagacatccagtccagagataccccttgatacacttaaatccaaagccataagtatg ctaacagaggcagtacagtgtagtggtactcatatacgagaccctgttggaggacacatt gcattccagtttgttcctgttcttaaactaatagcaacactgctcataatgggggttttt gatgatgatgatgtgaagcaggtgttaatcctcattgatccaaatgtatttggagatcac aaggaagaaacagaagagggtacagaaaaggaagaagttacacaagttgaagaaaaagct gtagaagctggagaaaaagcaataaaagaaaccaaagctcctacaacaggcttgttgcag acaagattaccagaatctgttaagcttcagatgtgccatttactcaattatttctgtgac tgtgagctgcaacatagagtggaagcaattgtatcatttgcagaccgttatgtatcaaaa ttgcagtataatcagaaatacaggtataatgaactcatgcaagccttgaacatgtctgca gctttgactgccaagaagactaaagaatttcggtctcctccacaagaacagattaatatg ctgctgaattttcaactgggagaggattgtccctgtccagaagagattcgggatgagctg tacgacttccatgatgatcttctaattcactgtggtattccactagaagaggaagaagag gaagaggaagattccaccttgactggcaaactccgttcgttaatatacaaaatcaaaggt ccaccaaaagcagaaaaagtagagcctagagaagaagaagagaaatcacctactacactg aaggaactcatatcccagactatggtacgctggtctcaggaagatcagattcaagatcca gaattagttcggattatgtataccctccttcgtaggcaatatgacagcattggtgagcta cttcaagctctgaggaaagcatacaccattagtgctgcctctgtgaaggatacaattaat ctgcttgctgcactgggccagattcgctcacttctcagtgtcagaatgggaaaagaggag gaattgctaatgattaatggattaggggatataatgaacaacaaggtgttttatcagcat cctaacttaatgagagtcttgggcatgcatgagacagttatggatgtgatggtgaatgtg cttggaggagataagtctcagcagatcgcttttcctaagatggtggcaagctgttgtcga ttcctgtgctacttctgtcgaattagtcgccaaaaccaaaaagccatgtttgagcatctt agttacttactggaaaacagcagcgttgggctggcatttccttcaatgagaggttcaaca ccactagatgttgcagcagcctccgtaatggacaataatgagcttgcactagcactggaa gagccagatctggataaagttgttacttatttggctggttgtggcctgcagagttgtcca gtattgctagctaaaggatatccagacattggatggaatccaatagagggtgaacgttac ctgtcattcttaagatttgcagtttttgttaacagtgaaagtgttgaagaaaatgcaagt gttgttgtcaagctccttattcgacgaccagagtgctttggaccagaccttagaggagaa ggaggaaatggtttactggcagctatgcaagaagctatcagaatctcagagaatccttct cgtgaccttccctcacaaggatataagagagaaggtgatgaggaggaggaagaggaggag attgtgcacatgggcaatgcaatcatgtcattttactcagctctcatagatttacttgga cgctgtgcaccagaaatgcatcttattcaaagtggaaaaggtgaagctattcgaatcagg tcaatcctccgatctctagtgccaactgaagatttggttgggattataagtataccgcta aagctgtcaacagttaacaaagatggcacagtaaatgagccagatatgtctgcaaatttc tgtcctgatcataaagcaccaatggtactcttcttggaccgtgtatatggtattaaggac caaaccttcctccttcacctattggaagttggatttttaccagatttaagagcttctgcc tctctggatacagtttctctaagtaccacagaggcagctctcgcactaaatagatatatt tgttcagctgtgtttccattactcaaaagatgtgctcccctcttttctggaacagagcat catgcctctttggttgactccatgcttcacacaatatataggttatccaaaggacgttcc cttacaaaagcacagcgagacactattgaagaatgcctgcttgctatttgccaccactta cgtccctctatgctacaacagctgttgagaaggctagtttttgatgtaccactactcaat gagtactgtaaaatgcctctcaagcttctgacaaatcactatgaacagtgctggaagtat tattgtctaccttcaggaatgggaagctatggaattgcagcagaagaagaattacattta actgagaaacttttctggggaatatttgattccttgtctcataagttcctatctctcctg cagaagtacgatccagagctctttcgaatggccttgccttgtctaagtgctatagctggt gccttgcctcctgattatttagatacacgaattaggtcaactttggaaaagcagacttca gtggatccagaaggaaattttgatcccaaacctgtcagtacagcaaaccttgtacttcct gaaaagttggagtatattgtcagcaagtatgctgaacattcccatgataagtgggccttt gataagactaataatggatggaaatacggtgtttcactggatgaaaatacgaagactcac ccattaataagacctttcaaaactttaacagaaaaggaaaaagaaatttatcgttggcct gctagagaatcactgaaaaccatgttggccatgggatggagcctagaaaggaccaaagaa ggaggagaaacaatattacatcagcgtgaaaatgaaaagctccgcagcatatctcagtct agccagggaaatggatatagcccagcaccacttgatctctctaatgtggtgctttctagg gagcttcagggaatggttgaggtaatggcagaaaactaccataatatatgggccaaaaag aagaaaatggagttggaaagcaaaggtggaggtagtcatcctttattggtaccttatgac acattgacagccaaggagaaatcacgggaccgtgaaaaggcacaggagctgtttaaattc cttcaagtgaatggtataatcatatctcggggtctgaatgacatggatttggatgcttca tccatggaaaagaggtttgcctttaagtttctgaagaaaattttaaaatatgttgactct gctcaagagttcattgcacatttggaagccattgtaaccagtggaaaaactgaaaaatct ccacatgaccaagaaataaaattctttgcgaaagttcttttaccattagttgatcagtac tttacaaatcactgcctgtacttcctgtcttctccaacaaaaacactcagtagcagtgga tatgcatcgaataaggaaaaggaaatggtagcaagcctgttctgcaaactagctgctctt gttagacataggatctcaatttttggtagtgattctacaacaatggttaactgcctgcac atcttagctcagtctcttgacactcgaactgttatgaaatcgggatctgagttagttaaa gctggattacgtgccttttttgaaaatgcagctgaagatctggaaaaaacttcagaaaat cttaaacttggaaaatttacccattcacgaacacaaatcaagggtgtttcacagaatatc aattatactacagtagcattgttacctgtcttgacatcaatttttgagcatatttcacag tatcagtttggagttgatttacttttgggtgatgtacaggtttcatgttatagaattctt tgtagcctctattcccttgggactgggaagaacatctatgttgaaaggcagcgccctgca cttggtgagtgcttagcatctcttgcagcagccattccggtagcatttcttgaaccttct ctcaaccattacaacccattgtctgtcttcaacacaaaaagtgcaagagaaagagcaatt ttaggtatgcctgatacagtagaggagatgtgtccagagatcccccagttggatggacta ataaaggaaattaatgatttagcagagtctggagcaaggtatactgaaatgcctcatgta attgaggttatcttacccatgctatgcaactatttgtcctactggtgggaacgagggtct gagagtgttcctgaaagtgccgggcctttctgtacgatgataacatctgaacatctaagc atcattctgggaaacattctgaaaatcattaacaacaatctgggaatagatgaagcatct tggatgaagagaattgcagtttatgctcagcctatcatcagcaaagccagaccagatctg ctgaaaactcactttattccaacactggagaaattgaagaagaaagctataaagattgtg atggaagaggagcaactgaaagcagacagtaaaactgacacccaggaagctgagctactc attctcgatgaatttgctgttctttgtagagacctctatgccttctatccaatgttgata cgttatgtagacaacaacagagccaattggctaaagaaaccagatgcagactctgatgaa ctcttccgaatggtagctgaagtttttatcctgtggtgtaaatcacataatttcaaaaga gaagaacaaaattttgtgattcaaaatgaaatcaacaacctggcatttttaacaggagat accaaaagcaagatgtctaaatctggaggacaagatcaagaaagaaagaaatcaaagcgt agaggggatttgtactccatacaaacatccttgattgtagctgcacttaaaaagatgctt cctattggcttgaatatgtgtactcctggagatcaagagctcatctctttggctaagact agatacagccatagggacactgatgaagaagtcaaagagcatttacgtaacaacttacat ttgcaggaaaagtctgatgatccagctgtgaaatggcagttaaatctgtataaagacatt ttgaaaaatgatgagcctagtgaccctgagaaaaacgtggaacgtgtgcagaggatatca gctgctctctatcatctggagcaggttgaacaaccactgagatccaagaaagctgtttgg cataaactcctgtcaaaacaacgcaaaagggctgttgttgcttgttttagaatggcacca ttgtacaacctgcccagacacaaaattagcaatttcttcctgagcacctttcaacgtgtt tggctggaaaaagtacatgaaaaaactcagtatgacaggcttatactcaagttaacgaca cctccaaaaaaagatgaagaagaagaggaagatactgagaaaaaacagcctgatccactt catcagattatcctttattttagtcgcaatgctctcacggagaggagcaaactagaagat gatcctttatatatcgcctattctgccatgatggcaaagagctgtcaggaagaagaggag gaagaagaggaagaaaaagagaagacatttgaggagaaagaaatggaaaagcagagaaca ctttaccagcaagctcgcttgcatgatcgtggagctgctgagatggtccttcagatgatt agcgcaagcaaaggtcatacaggacccatggttgttgaaacattaaaacttggtattgct attctaaatggtgggaataccatagttcaacagaaaatgttagactacctgaaggagaaa aaggatgctggattctttcaaagtctctctggcttgatgcagtcctgcagtgttcttgac ttgaatgcgtttgagagacaaaataaagcagaaggcctgggaatggttactgaagaagga actctcatcgttcgtgagcgtggtgaaaaagtgttgcagcatgatgaatttactcgagat ctatttagatttttacaactgctctgtgaagggcataacaatgattttcaaaattaccta cgtactcagatgggcaacaccacaacagtgaatattatcattagtactgttgactatctc ttgcgtcttcaggaatcaatcagtgacttttattggtactattcaggaaaagatgtcatt gatgaatcaggacaacgtaacttctctaaagctttggctgtcaccaaacaaatattcaat tcccttacagaatatattcagggcccttgcataggtaaccaacaaagtctggctcatagt aggctgtgggatgcagttgttggctttcttcatgtctttgccaatatgcagatgaaactt tcacaggactctgctcagattgaattgcttaaagaactgctagatctactaaaggatatg gtagtcatgctgttgtcactgctcgaaggtaacgttgtaaacggaacgattggaaaacaa atggtcgatacgcttgtagaatcatctagcaatgtagaattgattttgaaattttttgac atgttcctgaaattaaaagacctaactaactcagatgctttcaaagaacatgacccagat ggtaaaggcataatttcaaagaaggaattccagaagtcaatggaggctcaaaaacaatat atacagtcagagattgaattcctgctatcctgtgcagaagctgatgaaaatgacatgttt aactatctcgattttgtggaaagattccatgaaccagccaaagacattggatttaatgta gcagtattgctaacaaacctttcagaacacatgcctaatgattcacgccttcagagctta cttgaacctgcagaaagtgttcttaattattttgaaccataccttggccgtattgaaata atgggtggagccaagaaaatagaaagagtttactttgaaattagtgagtctagtagaatg cagtgggagaagccacaggtgaaggaatccaaaaggcagttcatatttgatgttgtaaat gaaggtggagaacaagaaaagatggagctctttgtgaatttctgtgaagacacaatcttt gaaatgcagttagcatcccagatctctgaaactgattcagctgaaaggcctgaggaagag gaagaagaagagtcttgctatgttgtagatattggagatgatgaggaagaagaaaaatcc ctggaatctccttcagcttttgcaatggcctgtgctgcagtgaagaagaatgttaccaac ttttttaaaatggttactgtgaagaacctaagaaaacagtacaggaaagttagaaagatg acagtaaaagagatggtgaaagtgtttttctcctttttctggatcctatttgtagggatg ttccaactgttctttactatagtgtggggaattttccagattctttggagcactgtattt gggggtggccttgttgaaggagccaaaaacattaaagtcactaaaatattaggggacatg cctgacccaacacagtttggaatccatgatgatgttacagaagcagaaaaagctgaaggt gctgagcatggcattagagctgaacttgtccagtttgtaaagggcgaaaaggcagaaact gacattatctctgatatttttggcattcctaccaaaaaagaaggtggctcaaaacatggt catgatgctggacttggggatattgcagaaatgcttggttctgatatccagtcttctttg gaaaacacagttcgtaagaaaaaaggattacagctatctgaaattgcaaaagaagctgaa gcagaaagaaaagtggaagctgagaaggctgacatggaagatggtgagaaagaagataga gcaaaggaagtacagtctgagcagctggaagagggtaaggtgaagaaaaagaagagaagg catggacaaaaaattgagaaacctgaggctgttatggctaacttcttcaaagctttggaa atttatcaaacaaaaatgctgcactacctagcaagaaatttttataacttacggtttctt gctctatttgttgcatttgctatcaacttcattctactattttacaaggtgacagaagag ccacttgatgaggtcgaggaagactctaatctctggaacacttttgatgaagaggaagag gaggaaggcatggtgttttttgttttagaagaaagtacgggttacatggcacctgctctc agagcattggcagttatccataccatcatctcctttgtctgtgtgattggatactattgc ttaaaggtccctctggttgtattcaaaagagaaaaggaagtagctaggaagctggaattt gatggattatacataactgaacagccatctgaagatgatattaaaggacaatgggatcgc ctggttataaacacaccgtcctttcctaacaattactgggacaaatttgtaaaacggaag gttattaacaagtatggagacttatatggagcagagcgcatagcagaacttttgggtttg gacaaaaatgcccttgattttagtccagtggaagagagtgaaccagaagaggcgtctctt ctatcatggttaagctccattgatacaaagtaccacatttggaagctcggtgttgttttc actgataattcatttttatacttagcttggtacacaactatgtctatccttgggcactac aacaacttcttctttgctgctcatctgctggatattgctatgggtttcaagactttgcga accattctgtcttcagtcactcacaatggcaaacagcttgtgctcactgtaggactcctg gctgtagtagtgtatctttacaccgttgtggcgttcaactttttccgcaaattctacaac aaaagtgaagatgaagatgaaccagacatgaaatgtgatgacatgatgacgtgttacctc ttccacatgtatgtgggtgtaagagctggtggtggcattggggatgaaattgaggatcct gcaggagacccttatgaaatgtatcgaattgtctttgacatcacatttttcttctttgtc attgttatcctactggccattattcaaggtctgattattgatgcttttggtgaattaaga gaccagcaagaacaagtgagagaagatatggagaccaaatgttttatttgtggaattggc aatgactattttgacacaaccccacatggctttgaaacacatactttgcaagagcacaac ttggcaaactacctgttctttttaatgtatctcataaacaaggatgaaactgagcatact ggccaggaatcatttgtgtggaagatgtaccaagaaagatgttgggattttttcccagca ggagactgcttccggaaacagtatgaggatcaacttggctaa

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