Anguilla anguilla (European eel): 118228062 Help Entry 118228062         CDS       T07545                                  Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism aang  Anguilla anguilla (European eel) Pathway aang04020   Calcium signaling pathway aang04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:aang00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     118228062    04020 Calcium signaling pathway     118228062  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:aang04040]     118228062 Ion channels [BR:aang04040]  Voltage-gated cation channels   Ryanodine receptor    118228062 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 Ins145_P3_rec SPRY MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_8 EF-hand_6 EF-hand_5 Motif Other DBs NCBI-GeneID:  118228062 NCBI-ProteinID:  XP_035275177 LinkDB All DBs Position 1:17330560..17456973 Genome browser AA seq 4899 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQCVASIQKENRKFCLTAEGLGNRLCYLEPTSEAKYVPP DLCICNFVLEQSLSVRALQEMLAKTGPNSEGPPDHDRWRLIRKAAQGGGHRTLLYGHAIL LRHSFSGMYLTCLKTSRSLTDKLSFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRIGDD LILVSVSTERYLHLSISNGNIQVDASFMQTLWNVHPTCSGSSVEEGYLLGGHVMRLFHGH DETLTIPGSDQSEEEQRIVNYEAGKAGAKARSLWRLEPLRISWSGSHIRWGQPFRLRHLT TGHYLALTEDRGLVLQDREKSDTKSTAFCFRASKDKQDSSPKRDVEGMGVAEIKYGDSIC FVLHVASGLWLSYQAPDVKSSRLGPLKRRACLHVEGHMDDGLTLQRCQHEESRAARIIRN TTRLFSHFIRDLDSLRGKNRVAVALHIEEVLQTLNDLITYFQLPDAELEHEEKQIKLRSL KNRQNLFKQEGMLTLVSNCIDRLNLYNSAAHFGESAGEEAAGAWKDILNLLYELLAALIR GNRNNCTQFSQNLDWLVSKLERLESSSGILEVLHCILIESPEALNIIQRGHIKSIISLLY KHGRNHKILDVLCSLCVCNGVAVRANQNLICDNLLPKRDLLLQTRLVNDVQSMRPNIFLG MSEGSAQYRKWYYELMIDQVDHFLTSEPSHLRVGWANSKGYAPYPGGGEGWGGNGVGDDL YSYSFDGLHLWSGRIPRAVASISQHLLTSDDVVSCCLDLGAPSISFRINGQPVQGMFENF NTDGLFFPVVSFSAGVKVRFLLGGRHGDFKFLPPSGYAPCYEALLPKEKMRVEPVKEYKR DFDGVRDLLGTAQFMSQASFIPMPVDTSQIVLPPHLEKVRDKLAENIHELWGMNKIELGW SYGKRMRDDNKRHHPCLVDFSKLPETEKNYNLQMSTETLKTLLALGCHVVHINIDAEEDL KKMKLPKNYMMSNGYKPAPLELSDVKLTPGQEVLVDKLAENAHNVWAKDRIKQGWTYGIQ QDLKSKRNPRLVPYALLDERTKKSNRDSLREAIRTLIGYGYNIDPPDQESAAHTSERLSI DKIRFFRVEQTYAVKTGRWYFEFEAVTGGDMRVGWARPGCRPDIELGMDDQAYVFDGFRG QRLHMGGRFFGRSWHAGDVVGCMINMEDKSMIFTLNGEILITNKGSELCFADFETEDGFI PVCSLGLSQTGRMNLGKDASTFKYYTMCGLQEGFEPFAVNMNRDVTMWFSKRLPTFVNVP KDHNHIQVTRIDGTIDSPPCLKVTHKTFGTQNSNADMVFCRLSMPVEFQTAFRSNPSIDM NGVHEDDSQKPKHRYPVKSLKHSEDGRRADYSSITTYYHSVRVFAGQDPSCVWVGWVTPD YHYYSNHFNLSKNRTVTVTLGDERGRVHESLRRSNCYMVWGGDIASASHTSGRSNVDLEI GCLIDLMTGHVNFSANGKELPTSYQVEPNSKLFPAVFVLPTSPNLFQFELAKIKNAMPLS SAIFKSEHKNPVPQCPPRLDVQTITSVLWSRMPNTFLKVETARVSERHGWVVQCLEPLQM MAVHIPEENRCVDIMELSELDDLRKFHYHTLKLYCALCALGNTRVAHALCSHLDQSQLLY TIDNQYLAGMLREGFYNVLISIHLETSKEARLMMNNEFIIPVTDETRSIRLFPDESKRHQ PPGVGLSTSLKPRFNFAPPCFISIKRDQHLSSPEIPLDILKEKAISMLTEAVQGGGHHIR DPVGGSVEFQFVPILKLIGTLLIMGILGSEDVQKILLLIDPNVFGERKEEEPEQATEKED VTSNEEKAVEAGEEEAKDGKQPVKGLLEKRLPESVKRQMCELLHYFCDCELKHRIEAIVS FSDSFVSKLQYNQKFRYNELMQALNMSAAITARKTKEFRSPPQEQINMLLNFSMGEDCPC PEDIQEELYEFHNELRLHCGIPIEEEEEEQDTSIKGRLLALVYKIKGPPQKTEENPTEEE QAAPTNLKELISQTMVSWAQECHIQDPELVRVMFSLLRRQYDCVGELLRAMRKSYTISAA SVKDTINLLASLGQIRSLLSVRMGKEEERLMIDGLGDIMNNKVFYQHPNLMRVLGMHETV MEVMVNVLGGDKSQEIAFPKMVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLAS PAMRGSTPLDVAASSVMDNNGLALALEEPDLEKVVMYLAGCGLQSCPMLLAKGYPDIGWN PIEGERYLSFLRFAVFVNGESVEENSSVVVKLLIRRPECFGPALRGEGGNGLLAAMKEAI KISENPSMDLPSSAHGVSSVMPADGEEEEEVVHMGNAIMSFYSALIDLLGRCAPEMHLIN KGKGEALRIRAILRSLVPTEDLVGIISIPLKMPIVNKDGTVTEPDMSASFCPDHKAPMVL FLDRVYGIEDQSFLLHLLEVGFLPDLRASASLDTEALSTTETALAMNRYIGSAMLPLLTR CASHFGGTEHYAALIDSTLHTIYRLSKGRSLTKAQRDAIEECLLAICKYLRPSMLQQLLR RLVFDVPLLTEYCKMPLKLLTNHYEQSWKYYCLPSGGGGFGMASEEELLLTKKLFWGIFD SLSQKKYEQELFKMAMPCLSAIAGALPPDYVDASLSTTLEKQTSVDAHGNFDPRPISTAN ISLPEKLEYVANKYAEHSHEKWSAEKVTLGWKYGESIDEKAKTHPMMRPYKSLTDKEKEV YRWPVKESLKTMLAMGWNIERTKEGEAMFQQRESEKLRKISQSSQGNGFNPCPLDMSNVV LSRELQGMVEIVAENYHNIWAKKKKTELGSRGGGTHPLLVPYDTLTAKEKARDREKAQDL FRFLQVNGYAITRGLKDMEQDSSSMEKRFAYKFLKKLLKYVDSAQEFIAHLEAMATSGKK DKSPHEQEIKFFAKVLLPLIDQYFKNHSLYFLSSPSSNLGGSGYASNKEKEMLTSLFCKL AALVRHRISLFGSDSATMVSCLHILAHTLDTRTVMKSGSELVKAGLRTFFENAAEDLEKT LENLKLGKFTHSRSQMKGVSQNINYTTVALLPILTALFEHITQYHFGVDLLLDDVQLSCY RILTSLYSLGTGKNIYVERQLPALGECLATLAGAMPVAFLEPHLNVHNPWSVFNTKTPRE RAILSMPDSVEEMCPEMPRLDGLMKDINDMSESGARYTEMPHVIEVVLPMLCNYLSYWWE KGPENTSNGSSSSCCTTVTSEHLSVILGNILKILNSNLGIDEASWMKRIAVYAQPIISKA RADLLRTHFLPTLEKLKKKTVKVVAEEELLKADSKGDTQEAELLILDEFAVLCRDLYAFY PMLIRYVDINRSRWLKEPDADSNALFKMVAEIFILWCKSHNFKREEQNFVVQNEINNLSF LTGDSKTKMSKSFLGKTGGQDQERRHKKRRGEFYSIQTSLIVAALKKLLPIGLNMCTPGD QELISLAKIRYSLKDTDEEVKDHLRQNLHLQEKSEDPAVRWQLNLYRDVVVKSDGPPDPE RTVARVQSISAAVFHLEQVEQPLRSKKCVWQKLLSKQRKRAVVACFRMAPLYNLPRHKNN NYFLNAYQHYWLEKMHENTDYDSLLSMLTKVHKKVEEEEEEEAEVQPDPLHQLILHFSHN ALTERSALDEDPLYIAYADMMAKSCAENEEEEEEEGKEKTFEEKEMEKQKTLYQQARLHD RGAAEMVLQMISASKGRLGPMVTFTLKLGISVLNGGNVVVQQKMLDYLKEKRDVGFFKSL SGLMQSCSVLDLNAFERQNKAEGLGMVTEEGSVNVSERGSKVLQNDEFTKDLFRFLQLLC EGHNNDFQNFLRTQTGNTTTVNIIISTVDYLLRLQESISDFYWYYSGKDVMDEPGQRNFS KALAVAKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSSQIEL LKELLDLQKDMVVMMLSLLEGNVVNGTIGKQMVDTLVESSSNVEMILKFFDMFLKLKDLT TSDSFKEFDPDSKGVISKKEFQKSMENQKQYTQSEIEFLLSCVEADENDMFNYEEFVERF HEPAKDIGFNVAVLLTNLSEHMPHDSRLAAFLDLAESVLNYFEPYLGRIEIMGGAKRIER VYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGESEKMELFVNFCEDTIFEMQLASQIS EPDAVERPEEDEDDAHSILEELEEEEEEHALESSSAFTIACVSMKKNLSHFRQQISVRNM RKQFKKFRKMSIREMIKGFFSFFWMIFTGLFRFMYNLVWGFFHILWTSMFGGGLVEGAKN MKVTDILGNMPDPTQFGIHGDVLESEKLETSESASGAEMVQMAKGDQSEVDLMTELMNIP PKREGGKHGPEPGLGDVSEIVGVDAPSLASAVKQKKAQKEAASKETSEVDQKAETEKADT EDGEKKDKAKEEEPSEPATEEKKVPKNRPGLKKEEPEAFMASFFAGLEVYQTKMLNYLAR NFYNLRLLALFVAFAINFILLFYKVTGDDSGDEDPDPWNGDDEDEDEGGMEYFVLQESTG YMAPTLRFLAILHTIISFLCVVGYYYLKVPLVVFKREKEIARRLEFDGLYITEQPSDDDI KGQWDRLVINTPSFPNNYWDKFVKRKVINKYGDLYGAERIAELLGLDKSALDFNPTEETV VKEASLVSWLSSIDTKYHIWKMGVVFTDNSFLYLVWYTTMSILGHYNNFFFAAHLLDIAM GFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDD MMTCYLFHMYVGVRAGGGIGDEIEDPAGDPYELYRILFDITFFFFVIVILLAIIQGLIID AFGELRDQQEQVKEDMETKCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINK DETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 14700 nt NT seq  +upstreamnt  +downstreamnt atggctgaaggtggagaaggggaggatgaaattcagttcttaagaactgatgatgaagtg gtgctgcagtgtgtcgcgagcatccagaaagaaaatcgcaagttctgcctgactgcggaa ggactcggaaatcgactgtgttacctggaacccacatcagaagcaaagtatgttcctcca gacttgtgcatctgtaactttgtgctggagcagtccctttctgtgcgggccctgcaggag atgctggccaaaactgggccaaacagcgaaggacctcctgaccacgaccgatggaggctc ataagaaaggcggcacaagggggtggacaccggaccctactctatggccacgccatcctc ctcaggcattccttcagcggaatgtacctaacctgcttgaagacgtcaaggtccttgaca gataaactgtcttttgatgtgggattacaagaggattcgacaggtgaggcctgttggtgg actatccaccctgcctcaaagcagaggtcagaaggagagaaagtgcgcattggtgatgac ctcatcctagtcagcgtgtccacagagcgctatctgcatctgtccatctccaacggcaac atccaagtggatgcctctttcatgcagactctgtggaatgtccaccctacctgctcaggc agcagtgtggaagaagggtacttgcttggtggtcacgtgatgcgtctgtttcatgggcat gacgagacccttaccattccagggtcagaccagagtgaagaggaacagaggatagtgaac tatgaggcaggtaaagcaggtgctaaagccaggtctttgtggagactggaaccgctcaga atcagctggagcgggagccacattcgctgggggcagcctttccgccttcgccacctcacc acgggtcactacctggcactgacggaggacagggggctggtgctgcaagaccgggagaaa tctgacacaaaatccactgccttctgcttcagagcctccaaggacaagcaggattccagc ccgaagcgagatgttgaaggcatgggggtggcagagattaagtacggagactcaatctgc ttcgtcctacatgtggcctcggggttatggctgtcctaccaggcgcctgatgtaaaatct tctcgcctgggacctctcaaaagaagggcctgtcttcacgtggagggccacatggacgac gggctgacccttcagcgctgtcagcacgaggagtcccgggctgcccgcatcatccgcaac accacgcggctcttcagccacttcatcagagacttggacagcctgagagggaagaatcgc gtggcggtggccctgcatattgaggaggtcctgcagaccctgaatgacctcatcacctac ttccagcttccagatgccgagctggagcacgaggagaaacaaatcaagttgcgttcactc aagaaccggcaaaacctcttcaaacaggaaggaatgctgactctggtgtccaactgcatc gaccggctgaacctgtacaacagtgcggcgcacttcggggagagcgccggggaggaggcg gccggggcctggaaggacattctcaacctgctatacgagctgctggccgccctgatccgc gggaacagaaacaactgcacccagttctcccaaaacctggactggctggtcagcaagctg gagagactggagtcctcatcaggaattcttgaggttcttcactgcatcttaattgaaagc ccggaggcgctcaacatcattcagagaggacacattaagtccatcatctccctgctgtac aaacacggacggaaccacaagattttggacgttctgtgttccctctgtgtttgcaatgga gtggctgtaagagccaatcagaacctcatttgtgataacctgctcccaaagagggacctg ctcctccagacgcgattggttaatgatgtccaaagcatgaggcccaatattttccttggc atgagtgagggctcagcacagtacaggaagtggtactatgagctgatgattgaccaggtg gaccatttcctgaccagtgagccgtctcacctgcgtgtgggctgggcaaactccaaaggg tacgccccctatcctggagggggcgagggttggggtggaaatggcgtgggggacgacctg tactcctatagctttgatggtcttcacctctggtcaggtcggattccccgggcagtggcc tccatcagccagcacctgctgacctcggacgacgtggtgagctgctgcctggacctgggg gcccccagcatctccttccggatcaatgggcagcctgtgcagggcatgtttgagaacttc aacaccgacgggctcttcttccctgttgtcagcttttctgccggggtcaaagtgcgattc ctgttgggcggtcgccatggcgacttcaaattcttgccaccctctggttatgcgccgtgc tacgaagctctgctgcccaaggagaaaatgcgagtggagccggtgaaggagtacaagcga gactttgatggcgtgagggatctgctgggcaccgcacagttcatgtcgcaggcttccttc atacctatgcctgtggacaccagccagattgtgctgcctccgcaccttgagaaagtacgg gacaaactggctgaaaacatccatgaactgtggggtatgaacaagattgaacttggctgg tcttatggtaagcggatgcgagatgacaacaagaggcatcatccctgccttgtggatttc tccaaactccctgaaactgaaaagaactataacctgcagatgtcaactgaaactttaaag accttgttggcgttaggatgccacgttgtccacatcaatatcgatgcagaagaagacttg aaaaagatgaaacttcccaagaactacatgatgtctaatggttataagcctgcgccactg gagctttctgatgtgaaactgacccctggtcaggaagttctggtcgataaactggccgag aatgcccacaatgtctgggccaaggacaggataaaacaaggatggacctatggcattcag caggatttgaagagcaagcgcaatcctcgcctggtgccatatgctttattagatgagcgc acaaagaagtcgaaccgagatagcctccgcgaggctatccgaacactgattggatacgga tacaacattgatcctcccgaccaagagagtgcggcgcatacctctgagaggctgagcatc gataagatacgcttcttccgcgtggagcagacgtacgctgtgaagaccgggaggtggtac ttcgagtttgaggcggtgacgggcggagacatgcgtgtgggctgggcgcgacctggctgc aggcctgacattgagctgggcatggacgaccaggcctacgtgtttgatgggttcaggggt cagcggctgcacatgggaggcagattcttcggtcgcagctggcacgcaggagacgtggtg ggctgcatgatcaacatggaggacaagtccatgatcttcaccctcaacggcgagattctc atcaccaacaaaggctccgagctctgcttcgctgactttgagactgaagacggcttcatc ccagtgtgtagcctgggcctttctcagaccggccgcatgaaccttgggaaggatgctagc accttcaagtactacaccatgtgcgggctccaggagggctttgagccttttgccgtcaac atgaatcgagatgtcaccatgtggttcagcaagcgcctaccaacctttgtcaatgtgcca aaggaccataaccacattcaggtaaccagaattgacgggactattgacagcccaccctgt ctcaaagtgacccacaagaccttcgggacccagaacagcaacgctgacatggtgttctgt cgtctgagcatgcctgtggaattccaaacggccttcaggagcaacccgtcaattgacatg aacggagtgcacgaagacgactcccaaaaacccaaacacaggtatcccgtgaagtccctg aaacactctgaggatggaagaagggcggattacagcagcatcacaacgtactaccactct gttagggtgtttgcagggcaggacccttcctgcgtgtgggttgggtgggtcaccccggac taccattactatagcaaccacttcaacctcagcaagaatcgaactgtcactgtaaccctg ggagatgagcgtgggcgagtccatgagagtctgaggaggagcaactgctatatggtgtgg ggcggagacatcgcgagcgcctcccacacttccggtcgtagcaatgtagaccttgagatt ggctgcctcatcgacctaatgacaggccatgtcaacttctctgccaatggcaaggagcta ccaacctcttaccaggtggaaccaaattcaaagctcttcccagcagtttttgtgctgcca actagtcccaacctgttccagtttgagttggcaaagataaagaacgccatgcccctctcc tcggctatcttcaagagcgagcacaagaaccctgtgccgcagtgcccgcctcggctggat gtgcagactattacctcggtgctgtggagccgcatgcccaacaccttcctgaaggtggag acggcccgggtcagcgagaggcacggctgggtggtgcagtgcctggagccactgcaaatg atggctgtgcacatccctgaggagaacaggtgtgtggacataatggagctctcagaacta gatgacctgaggaaattccactaccacacactgaagctgtactgcgccctctgtgctttg ggaaacacccgggtggctcacgccttgtgcagccacctggaccagtcccagctgctctac accatcgacaaccagtacctggcgggcatgctgcgcgagggcttctacaacgtgctcatc agcatacacctggagacctccaaggaggcccggctcatgatgaacaacgagttcatcatc ccggtcaccgacgagacacggagcatccgcctctttcccgacgagtccaagaggcaccaa cccccgggcgtggggctcagcacgtcgcttaagccccgcttcaatttcgccccgccctgc ttcatctccatcaagcgagaccagcacctctccagccccgagatccccctggacatcctg aaggagaaggccatcagcatgctgacggaggcagtgcagggtggcggtcaccacatccgc gaccccgtggggggcagcgtggagttccagttcgtgcccatcctcaagctgatcggcaca ctccttatcatgggcattctgggaagcgaggacgtgcagaagatcctgctgctcatcgac cccaatgtctttggcgagcgcaaggaggaggagccagagcaagccaccgagaaggaggac gtgaccagcaatgaggagaaggccgtggaagcaggagaggaggaggccaaagatggcaag cagcctgtgaagggcttgcttgagaagaggctgccagagtcagtcaaaaggcagatgtgt gaactgcttcattacttctgcgactgcgagctgaaacaccgaatcgaggccatcgtgtcc ttctccgacagcttcgtgtcgaagctgcagtacaaccagaagttccgatacaacgagcta atgcaggccctcaacatgtccgccgccatcacagcaaggaagaccaaggaatttcgatcc ccaccgcaagagcagattaacatgcttctgaacttcagtatgggagaggactgtccctgc ccagaggatatccaagaggagctgtatgagttccacaatgaacttcgcctgcactgtgga atcccgattgaagaggaggaagaggagcaggacacctccataaaaggccgcctccttgcc cttgtgtacaagatcaaaggtcccccccagaaaacagaggagaatcctacagaagaagaa caggctgcacctaccaacctgaaggagctgatctcccagacgatggtgagctgggcgcag gagtgccacatccaggacccggagctggtgcgcgtgatgttcagcctgctgcggcggcag tacgactgtgtgggcgagctgctccgtgccatgaggaagagctacaccatcagcgccgcc tccgtgaaggacaccatcaacctgctggcctccctgggccagatccgctccctgctcagc gtgcgcatggggaaggaggaggagaggctcatgattgacggcctgggtgacatcatgaac aacaaggtgttctaccagcaccccaacctgatgcgggtcttgggcatgcacgagactgtg atggaggtgatggtcaacgtgctgggaggagacaagtcacaggagatcgcctttcccaag atggtggccagctgctgtcgattcctgtgctatttctgccgcatcagtcggcagaaccag aaggccatgttcgaccacctgagctatctcctggagaacagcagtgtgggcctagcatct ccagccatgaggggctccactcccctggatgtggccgcatcctcagtgatggacaacaac gggctggccctggcactggaagagcctgacttggagaaggtggtgatgtatctggcgggc tgtgggctccagagctgcccaatgctcctggcaaagggataccccgacatcggctggaac cccattgaaggggagcgctacctgtccttcctccggtttgcagtcttcgtcaatggtgaa agcgttgaggaaaactctagcgtggtggtgaagctgttgattcggcgtcctgagtgtttt ggcccagcgctccggggagaggggggcaatggcctgttggccgctatgaaagaggccatc aagatctcagagaacccctccatggacctgcccagctccgcccacggggtcagctcagtc atgcccgccgacggcgaggaagaggaagaggtggtgcacatgggaaacgccatcatgtcc ttttactccgccctcattgacctgctggggcgctgcgctccggagatgcaccttatcaac aagggaaaaggagaggccctgagaatccgtgccattctgcgctccctggtgcccacggag gacctggtgggcatcatcagtatacccctcaaaatgcccatagtgaataaagacggcacc gtgacggagcctgacatgtcggccagcttctgtccggaccacaaggcccccatggtgctg ttcctggaccgtgtgtatggtatcgaggaccaaagcttcctgctgcacctgctggaggtg ggattcctgcctgacctgcgggcctctgcctccttggacacggaggcgctgagcaccacg gagacggccctggccatgaacaggtacattggctcagcgatgctgccgctgctgacccgc tgcgcctcgcacttcggcggcaccgagcactacgccgccctcatcgactccacgctgcac accatctaccggctgtccaagggccgctcgctcaccaaggcccagcgtgacgccatcgag gagtgcctgctcgccatctgcaagtacctgcgtccctccatgctgcagcagctcctgcgc cgcctcgtcttcgacgtgccgttgctgactgagtactgcaagatgcctctgaagctgctg accaatcactacgagcagagctggaagtactactgccttccctctgggggcggcggcttc ggcatggcgtctgaggaggagctgctcctcaccaagaagctcttctggggcatcttcgac tcgctctcacagaagaaatacgagcaggagctctttaaaatggccatgccctgtctgagc gccatcgccggggccctgccacccgactatgtggacgcctccctcagcaccaccctggag aagcagacctcggtggacgcccatggcaacttcgaccccaggcccatcagcacagccaac atttccctccctgaaaaactggaatatgttgccaacaagtacgctgagcattcccatgaa aaatggtctgcagagaaggtaacattaggctggaagtatggggagagcattgatgagaaa gccaagacacatcccatgatgaggccttacaaatcgctcaccgacaaggagaaggaggtt taccgctggcctgtgaaggagtctctgaagaccatgctagctatgggctggaacattgag aggaccaaggaaggggaggccatgtttcagcaacgggagagtgagaaactgcgcaagatc tcccagtcttctcagggaaatggcttcaacccatgtccactggacatgagcaatgtggtt ctttccagagagttacagggcatggtggagattgtggcagaaaattaccataatatttgg gcaaagaagaagaaaactgagctgggaagcagaggaggcgggacacaccccctgctggtg ccttacgatacgctgactgccaaggagaaggctagggacagagagaaggcccaggacctc ttccgtttcctgcaggtcaacggctacgccatcaccagggggctgaaggatatggagcag gactcgtcctccatggagaagcgctttgcgtacaaatttctgaagaagctgctgaagtac gtggactcggcgcaggaatttatcgcccacctggaggccatggccaccagcgggaagaag gataaatccccacatgaacaagagatcaagttctttgccaaggtgctcctccccctgatt gaccagtacttcaagaaccactccctctacttcctgtcctctcccagctctaatctgggt ggcagtggttacgcatccaataaggagaaggagatgctcaccagcctcttctgtaaactg gcagctcttgtcagacacaggatttccctctttgggagtgactctgccaccatggtgagc tgcctgcacatcctggctcacacgctcgacaccaggacagttatgaagtcaggctcagag ctggtgaaggcagggctgcgcactttctttgagaatgcggctgaggacctggagaagact ctagaaaacctgaagctggggaagttcacgcactcccgcagccagatgaagggcgtgtcc cagaacattaactacaccacagtggccctgctgcccatcctgaccgcgctgttcgagcac atcacccagtaccacttcggagtggacctgctgttggatgatgtccagttgtcctgttat cgtatcctgaccagtctttattcactaggaacaggaaagaacatctacgtggagaggcag ctgccggccctgggtgaatgtctggccaccctagcaggagccatgcctgtggccttcctg gagccccacctcaacgtgcacaacccctggtctgtcttcaacaccaagaccccccgagag cgggctatcctcagcatgccagactcggtggaggagatgtgcccggagatgccccgcctg gatggcctgatgaaggacatcaacgacatgtcggagtccggggcgcgctacactgagatg ccccacgtcatcgaggtggttctgcccatgctctgcaactacctgtcctactggtgggag aaggggccggagaacacatctaacggtagcagcagcagctgctgcaccacagtcacctcc gagcacctcagtgtcatcctggggaacatcctcaagatcctcaacagcaacctggggatt gacgaggcctcctggatgaagaggatcgccgtgtatgcccagcccatcatcagcaaggca cgggcggacctgctgaggacccacttcctgcccacactggagaagctgaagaagaagaca gtgaaagtggtggcagaggaggagctcctgaaggctgacagcaagggcgacacacaggag gcggagttgctgattctggatgaatttgctgtgctctgccgggacctctatgccttctac cctatgctcatccgctatgtggacatcaacaggtctaggtggttgaaggagccagatgcc gactccaatgcactttttaagatggtggcagagatcttcatcctctggtgcaagtcccat aacttcaaacgggaggagcaaaactttgtggttcagaatgaaatcaacaacctgtccttc cttactggagatagcaagaccaagatgtccaagtcatttctgggaaagacagggggtcag gaccaggagaggaggcacaagaaacggaggggggaattctactccatccagacctccctc atagttgcggccctgaagaagctgctgcccatcggcctcaacatgtgtaccccgggagac caggagctcatatctttggccaagatccgctacagtctgaaagatacggatgaggaagtc aaggaccacctgagacaaaatctgcacctgcaagagaagtcagaggatcctgcagtgagg tggcagctgaacctgtacagggacgtggtggtgaagagtgatggtcctccagaccccgag cgcaccgtggcccgagtacagagcatctccgctgccgtcttccacctggagcaggtggag cagccactgaggtctaagaagtgtgtgtggcagaagctgctctccaaacaacgcaagcgc gcagtggtggcgtgcttccgcatggctccactctacaacttacccaggcacaaaaataac aattacttcctgaacgcctaccaacactattggctggaaaaaatgcatgagaacacagac tatgacagtctgctctccatgctaacgaaggtccacaagaaggtggaggaggaggaagag gaggaggcagaagtgcaacctgacccgcttcatcagctcatcctgcatttcagtcacaat gctctcaccgaacggagtgccctggatgaagatcctttgtacattgcttatgctgatatg atggctaagagttgtgcagaaaatgaagaggaggaagaagaagaagggaaagaaaagacc tttgaggagaaggagatggagaaacagaagactctgtaccagcaggccagactgcatgac cgcggggcggctgagatggtgctgcagatgatcagtgccagcaaaggtcggctgggaccc atggtgaccttcactctcaaactgggaatctccgtcctcaatgggggcaatgtggttgtc cagcagaaaatgctggattacctgaaggaaaagagagatgttggttttttcaagagttta tctggactcatgcagtcttgcagtgtcctggacttgaatgcatttgaaaggcaaaataaa gcagaaggtcttggaatggtcactgaggaaggatcagtcaacgtgagtgagcggggttcc aaggtactgcaaaatgatgagttcaccaaggatctctttaggttcttgcaacttctttgt gaaggtcacaacaacgacttccaaaacttccttcgtactcagacaggaaacaccaccaca gtcaatatcatcatcagcacggtggactaccttctccgtctgcaggagtccatcagcgat ttctactggtattactcgggaaaagatgtcatggacgagcctgggcagcgtaacttctcc aaagccctggctgtagccaagcagatcttcaactctctgactgagtacattcagggcccc tgtattggaaatcagcagagtctggcccacagtaggctgtgggatgctgtggtggggttc ttacatgtctttgccaacatgcaaatgaagctctcacaggattcaagccagattgagttg ttgaaggagctgctggacctgcaaaaggacatggtagtcatgatgctttcccttctggaa ggtaatgtggtgaatgggacaattggcaagcagatggtggacaccttggtggaatcctct agcaatgtggagatgatcctgaagttctttgacatgttccttaagctgaaggatctgact acttctgacagtttcaaggaatttgaccctgacagcaagggcgtaatctctaagaaggaa ttccagaagtccatggagaaccagaagcagtacacccagtctgagattgagttcctgctc tcctgtgtagaggccgatgagaacgatatgttcaactatgaagagtttgtggagcgcttc catgagcctgccaaggacattggcttcaatgtggcggtgctgctaaccaatctgtcagag cacatgccccacgactcacggctggctgccttcctagacctggccgagagtgtgctcaac tattttgagccctaccttggccgcattgagatcatgggcggcgccaagcgcattgagagg gtgtactttgagatcagtgagtccagcagaactcagtgggagaagccacaggtcaaggag tccaaacggcaattcatcttcgacgtagtcaacgagggcggagagagcgagaagatggag ctcttcgtcaacttctgtgaggataccatttttgagatgcagcttgcttcccagatatct gagccggatgctgtggagcgaccagaggaggacgaggatgacgcccacagcatcctggaa gaactggaagaggaagaggaggagcatgccttggagtcatcctctgccttcactattgcc tgtgtttccatgaagaagaacttgtcccacttccgtcagcagatctcagtcaggaacatg cgcaagcaattcaagaagttcaggaagatgagcatccgggagatgatcaagggtttcttc tccttcttctggatgatcttcactggtctcttccgcttcatgtacaacctggtctggggc ttcttccatatcctctggacttccatgtttggtgggggcctggtggagggcgccaagaat atgaaggtgacagacattctgggcaacatgcctgacccaacgcagtttggaatccatggt gacgtgctggaatcagagaaattggagacgagcgaatcagcatcaggggcagagatggta cagatggcaaaaggggaccagtctgaggtggatttgatgacggagctgatgaacatacca cctaagagagaaggggggaagcacggacctgaacctggcctgggagatgtctctgagatc gtcggagttgacgcaccttcattagctagtgccgtaaagcagaaaaaagctcagaaagag gctgcatctaaagagacatcggaggttgatcagaaggcagagacggagaaggcagacaca gaggatggcgagaagaaggacaaggccaaggaggaggagccttcagagcccgcaactgag gagaagaaagtccccaaaaacagacctggcctgaaaaaggaggaaccagaggccttcatg gccagcttttttgcaggattagaagtctaccagactaagatgctgaactatctggcgaga aacttttacaaccttcgcttgctggctttgtttgtcgcctttgccatcaactttatcctt ctcttctacaaggtgactggagatgactcaggtgacgaagaccctgacccctggaatggc gatgatgaagatgaggatgagggtggtatggagtactttgtgttgcaggagagcactggc tacatggctccaactctacgcttcctggctatactccacaccatcatctctttcctttgt gtggtgggatactactatctaaaggttcccctggtggtgtttaagcgagagaaggagatt gccaggaggctggagtttgatggcctgtacattacggagcagccctcggatgatgacatc aaaggacaatgggatcggctggtcatcaataccccatccttccccaataactactgggac aaatttgtgaagcgaaaggtcattaataagtatggggatctctacggggccgaacgtatt gcggagctattgggtctggacaagagtgccttggacttcaaccccacagaggagacagtg gtgaaggaggcctcattggtgtcctggctgagctccattgacacaaagtatcacatctgg aagatgggcgtagtgttcactgataattctttcctctacctggtgtggtacaccaccatg tccatcctggggcattacaataacttcttctttgctgcccacttgctggatattgccatg ggcttcaagacactgagaaccattctgtcctctgtcacccacaacggtaaacagcttgtg ttgactgtgggactgctagctgtggtagtgtacctctacacagttgtggccttcaatttc ttccgcaagttctacaacaagagcgaggacgaggacgagcctgacatgaagtgtgatgac atgatgacctgctatctgttccacatgtatgtgggcgtgcgtgctggcggtggtatcggt gacgagattgaggacccagcaggcgacccctacgaactctaccgcattctgttcgacatc actttcttcttctttgtcattgtcattctgctggccatcatccagggtctgatcattgat gcatttggagagctgagagatcagcaggaacaagtgaaagaggacatggagactaaatgc ttcatctgtgggattggtaatgactactttgatacgaccccacatggctttgagacacat accttacaagagcacaacctggccaactacctgttcttccttatgtacctcatcaacaag gacgagacggagcacactggtcaggagtcgtacgtttggaagatgtaccaggagagatgc tgggacttcttccctgccggggactgtttccgtaagcagtatgaggaccagctggggtag

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