Actinomyces sp. oral taxon 414: AM609_03840
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Entry
AM609_03840 CDS
T04083
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
acq
Actinomyces sp. oral taxon 414
Pathway
acq00300
Lysine biosynthesis
acq00550
Peptidoglycan biosynthesis
acq01100
Metabolic pathways
acq01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
acq00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
AM609_03840
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
AM609_03840
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
AM609_03840
Enzymes [BR:
acq01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
AM609_03840
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Hexose_dehydrat
Motif
Other DBs
NCBI-ProteinID:
ALD00541
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Position
949295..950776
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AA seq
493 aa
AA seq
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MCGGVLHAAQGTADSVRATTVTGVFTDSRKVAPGGLFVAIAGEHDDGHQFVPAAARAGAV
AILVHDLDGVRSALADAGLAPGSLNLITVSDTVEALGRLARAHLADLRERAAEQGRALTV
VAMTGSVGKTTTKDLTRQILAAQAPTIAPAASFNNEIGLPLTVLRADETTRFLILEMGAS
APGHIAYLTSIAPPDAAAVLVVGHAHMDGFGSLDGVARAKAEIIEGLLPTGTAVVNLDDE
RAAAMGELAPGPVLTFSAAGDARADLRADLVELDDGARPVIDLHLPGLSAPARVRLGLPG
VHNVTNALGAAGLALAAGVRPEAVAAALGRAVSESPHRMDVRELELTGLNGHSLGILLID
DSYNANIDSMTAALDALPALAGERRRVVIVSEMLELGESSAADHARTGELAVQAGAALLL
TIGRGAAPAAQAARAAGIKTLQVADADAALDLLGSEHSPLHDGDAVLVKGSHDSGAWRLA
DFLVERSKEGTQR
NT seq
1482 nt
NT seq
+upstream
nt +downstream
nt
atgtgcggcggtgtgcttcacgcggcgcagggcaccgcggactcggtgcgagccaccacc
gtgaccggcgtcttcaccgactccaggaaggtggccccgggcggcctcttcgtggccatc
gcgggcgagcacgacgacgggcaccagttcgtgccggccgccgcgcgcgccggggccgtg
gccatcctcgtgcacgacctggacggcgtgcgctccgccctggccgacgccgggctcgcc
ccgggctcgctcaacctcatcacggtgtccgacaccgtcgaggcgctcgggcgcctggcc
cgcgcccacctggccgacctgcgcgagcgcgccgccgagcagggccgcgcgctgaccgtc
gtggccatgaccggcagcgtgggcaagaccaccaccaaggacctgacccgccagatcctg
gcggcccaggcccccacgatcgccccggccgccagcttcaacaacgagatcggcctgcct
ctgaccgtcctgagggccgacgagaccacccgcttcctcatcctggagatgggggcctcc
gcgcccgggcacatcgcctacctcacctccatcgccccgccggacgcggccgccgtcctc
gtggtcggccacgcccacatggacggcttcggctccctcgacggcgtcgcccgcgccaag
gcggagatcatcgagggcctgctgcccaccggcaccgccgtggtcaacctcgacgacgag
cgcgccgccgccatgggcgagctcgcgccggggccggtcctgaccttctccgccgccggc
gacgcccgggcggacctgcgtgccgacctcgtcgagctcgacgacggcgcccgcccggtg
atcgacctgcacctgcccgggctgtccgcgcccgcccgggtccgcctgggcctgccgggc
gtccacaacgtgaccaacgccctgggcgccgccgggctcgccctggccgccggggtcagg
cccgaggccgtcgccgcggccctggggcgggccgtcagcgagagcccgcaccgcatggac
gtgcgcgagctggagctgaccgggctcaacggccacagcctggggatcctcctcatcgac
gactcctacaacgccaatatcgactccatgaccgccgccctggacgccctgcctgcgctg
gccggcgagcgccggcgggtcgtgatcgtctcggagatgctggagctgggggagtcctcc
gccgccgaccacgcccgcaccggcgagctcgccgtgcaggcgggggccgccctgctgctg
acgatcggccgcggcgccgcgcccgccgcccaggcggcccgcgccgccggcatcaagacc
ctccaggtcgccgacgccgacgccgccctggacctgctgggctcggagcactccccgctg
cacgacggcgacgcggtcctggtcaaggggtcgcacgactcgggggcgtggcggctggcg
gacttcctcgtcgagcggtccaaggagggcacccagcgatga
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