Acidithiobacillus ferrooxidans ATCC 23270: AFE_2075
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Entry
AFE_2075 CDS
T00810
Symbol
leuB
Name
(GenBank) 3-isopropylmalate dehydrogenase
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
afr
Acidithiobacillus ferrooxidans ATCC 23270
Pathway
afr00290
Valine, leucine and isoleucine biosynthesis
afr00660
C5-Branched dibasic acid metabolism
afr01100
Metabolic pathways
afr01110
Biosynthesis of secondary metabolites
afr01210
2-Oxocarboxylic acid metabolism
afr01230
Biosynthesis of amino acids
Module
afr_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
afr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
AFE_2075 (leuB)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
AFE_2075 (leuB)
Enzymes [BR:
afr01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
AFE_2075 (leuB)
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Motif
Pfam:
Iso_dh
DUF6259
Motif
Other DBs
NCBI-ProteinID:
ACK80053
UniProt:
B7J4T5
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All DBs
Position
complement(1824777..1825853)
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AA seq
358 aa
AA seq
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MKKIAIFAGDGIGPEIVAAARQVLDAVDQAARLGLHCSEGLVGGAALDASDDPLPAASLQ
LALEADAVILGAVGGPRWDAYPPAKRPEQGLLRLRKGLDLYANLRPAQIFPQLLDASPLR
PELVRDVDILVVRELTGDIYFGQPRGLEVVDGKRRGFNTMVYDEDEIRRIAHVAFRAAQG
RRKQLCSVDKANVLETTRLWREVVTEVAQDYPDVQLSHMYVDNAAMQLIRAPAQFDVLLT
GNMFGDILSDEASQLTGSIGMLPSASLGEGRAMYEPIHGSAPDIAGQDKANPLATILSVA
MMLRYSLGAELWAQRVEAAVQRVLDQGLRTADIAAPGAPVIGTKAMGAAVVDALNFKD
NT seq
1077 nt
NT seq
+upstream
nt +downstream
nt
atgaaaaaaatagccatatttgcgggtgacggcattggtccggaaatcgtggcggctgcc
cggcaagtgctggatgccgtggatcaggccgcgcggctcggcctgcactgcagcgagggc
ctggtgggcggcgcggcgctggatgccagcgatgatcccttgccggccgcctccttgcag
ttggctctggaggcggatgcggtcattctgggggcggtgggcggcccccgctgggacgca
tatccgcccgccaaacgcccggaacagggattgctgcgcctgcgcaaggggctggatctc
tatgcgaacctgcgtcccgcgcagatttttccgcagttgctggatgcttccccgttacgc
ccggagctggtgcgcgatgtcgacatcctggtggtgcgcgagctgaccggggatatctac
ttcggtcagccgcgtggtctggaagtggtcgatggcaagcgtcgcggctttaacaccatg
gtctatgacgaggatgaaatccgccgcatcgcccatgtggccttccgcgctgcccagggg
cgtcgcaagcagttgtgctcggtggacaaggccaatgtcctggagaccacacgtttgtgg
cgcgaggtggtcaccgaggtggcgcaggactatcccgatgtgcagctcagtcacatgtat
gtggataatgccgccatgcaactaatccgtgccccggcacagttcgatgtgctgctgacc
ggcaacatgttcggtgacattctttctgacgaggctagtcagttgaccggctccatcggc
atgctgccctcggcctcactgggcgagggccgggcgatgtatgagcccatccacggctcg
gcgccggacatagccgggcaggacaaggcgaatcccttagccacgattctgtccgtggcg
atgatgctgcggtattctctcggtgccgagctctgggcgcagcgggtggaggcggcggtg
cagcgagtactggatcaaggcctgcgtactgcagatatcgcggcgccgggagcgccggtg
atcggcaccaaagccatgggtgccgcggtggtcgacgccctgaacttcaaggattga
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