KEGG   Anopheles funestus (African malaria mosquito): 125763202
Entry
125763202         CDS       T09273                                 
Name
(RefSeq) CAD protein isoform X1
  KO
K11540  carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
Organism
afun  Anopheles funestus (African malaria mosquito)
Pathway
afun00220  Arginine biosynthesis
afun00240  Pyrimidine metabolism
afun00250  Alanine, aspartate and glutamate metabolism
afun01100  Metabolic pathways
afun01240  Biosynthesis of cofactors
Module
afun_M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:afun00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    125763202
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    125763202
   00220 Arginine biosynthesis
    125763202
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:afun01002]
    125763202
Enzymes [BR:afun01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.2  aspartate carbamoyltransferase
     125763202
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.3  dihydroorotase
     125763202
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)
     125763202
Peptidases and inhibitors [BR:afun01002]
 Cysteine peptidases
  Family C26: gamma-glutamyl hydrolase family
   125763202
 Metallo peptidases
  Family M38: beta-aspartyl dipeptidase family
   125763202
SSDB
Motif
Pfam: CPSase_L_D2 CPSase_L_D1 CPSase_sm_chain GATase OTCace_N OTCace CPSase_L_D3 ATP-grasp MGS Dala_Dala_lig_C DHOase Amidohydro_1 ATPgrasp_Ter ATP-grasp_3 Peptidase_C26 GARS_A DJ-1_PfpI
Other DBs
NCBI-GeneID: 125763202
NCBI-ProteinID: XP_049282468
LinkDB
Position
X:complement(4546758..4567627)
AA seq 2270 aa
MAEITMLPNEEAIVALPSEVRKQELSEYRPPTAYLVLEDGTIFPGHKFGADVSVDGEVVF
QTGMVGYPESMTDPSYHGQILVLTYPLIGNYGIPDADLDECGLMRHFESNNRIWTAGLVV
SEICHEPSHWRSKLTLSSWMWRHGVPGISGIDTRALTKKIRENGTILGKIVQSRVLSIAG
LNFSNQNLRNLVAEVSLAQPRTYNESGSPRILAIDCGLKLNQVRCFVSRGARLDVVPWNA
RPNPDEYDGLFLSNGPGDPEMCREVVENLRSLLNMKTAKPIFGICLGHQILSTAAGCRTF
KMRYGNRGHNLPCMHLGTRRCYMTSQNHGFAVDSNQMPVGWEELFTNLNDGTNEGIVHQT
KPYFSVQFHPEHTAGPADLEVLFDVFLEVVSEYKREPKKQHVSVKDRLNERLQYVPPVPI
DLERPKKVLILGSGGLSIGQAGEFDYSGSQAIKALKEERIQTVLINPNIATVQTSKGLAD
KVYFLPLTRYYVEKVIKAERPGGVLLTFGGQTALNVGIEMERAGLFSRYGVKIMGTPISS
IIETEDRKLFAERVAEIGEKVAPSAAVYSVSEALDAADTIGYPVMARAAFSLGGLGSGFA
SNAEELKALANQALAHSNQLIIDKSLKGWKEVEYEVVRDAYDNCITVCNMENVDPLGIHT
GESIVVAPSQTLSNREYNLLRSTAIRVIRHFGVVGECNIQYALNPESEEYYIIEVNARLS
RSSALASKATGYPLAYVAAKLALAIPLPDIRNSVTGVTTACFEPSLDYCVVKMPRWDLAK
FARVSKNIGSSMKSVGEVMAIGRTFEEAFQKALRMVDSVNGFDPYLKPVNEQELEQPTDK
RMFVLAAALKARYTVEQIYELTKIDRWFLRKLKGIIDFTDELEELEHGCVPEAAMLREAK
RLGFSDRMIAQCVKSTELAVRMQRKELGVLPFVKQIDTVAGEWPASTNYLYLTYSATEND
VEFPGQYTMVIGSGVYRIGSSVEFDWCAVGCLKELRRLNHKTIMVNYNPETVSTDYDMCD
RLYFEEISFEVVMDIYDAEQPMGIILSMGGQLPNNIAMDLHRQQARILGTSPESVDSAEN
RFKFSRKLDRKGISQPRWKELTNLESAIEFCEEVGYPCLVRPSYVLSGAAMNVAYSNQDL
KTYLKHASDVSKEHPVVISKFLVEAKEIDVDAVAADGVILCMAVSEHVENAGVHSGDATL
VTPPQDINRETLERIKEIARDIADLLDVTGPFNMQLIAKNNELKVIECNVRVSRSFPFVS
KTLDFDFVALATRVIVGHTDIEPVEVMHGRGLVGVKVPQFSFSRLAGADVMLGVEMASTG
EVACFGENRYEAYLKAMMSTGFQIPKKSILLSIGSYKHKMELLPSIRILEKMGYKLYASM
GTGDFYTEHGVEVESVQWTFDSFAAEDNGNGAGSELRHLAEYLANKQFDLVINPPMSGGG
ARRVACFMTHGYRTRRLAVDYSIPLVTDVKCAKLLVAAMQRIGGAPSMKTHIDCMSSRLM
VKLPGFIDVHVHLREPGAPHKETFATGTAAALAGGITMVLAMPNTQPAIVDRGAFQQAVE
LAQKGARCDYALYVGASSTNFSTVHELASQAAGLKLYLNETFTTLRLNGLSVWQAHLANW
PKRAPLCVHAERETMAAVLLLASLTDRPIHVCHVARKEEILLIKAAKERGLKVTCEVCPH
HLFLSTADLDRIGAGRGEVRPVLCSPEDQQALWDNLDVVDVFATDHAPHAREEKESERPP
PGFPGLETILPLLLTAVTEGRLTMDELVNKFHSNPRRIFNLPEQPNTYVEIDLSEEWIIP
DRPAHSKAHWTPFAGMRVKGCVHRVVLRGETAYVDGLVLVNPGYGQNVREWHGGKPPMAG
AASIERIDVLNHSIGSGSGVGLRTADLEPDLQTNEAFYQLLSPDGTNAHVKQLGVHFAGE
QSGMRSASPLPPRIRCDSTGNQSVVGKLEPISINTGLGGVRERQLAGRHVLTVDMFTKEH
LNEIFHLAQTMKSRVAKERLLDDLLRGKVMVSIFYEVSTRTSCSFAAAMQRLGGRIVHID
ETSSSAKKGETLEDSIQVIAGYADVVVLRHPLPGAVTRAAQHCRKPLINAGDGVGEHPTQ
ALLDIFTIREEIGTVNGLTITMVGDLKHGRTVHSLARLLTMYNVNLRYVCPAGLEMPSHI
KQYIDKKGISQRQYDSLETAIIDTDVLYMTRIQRERFESEQEYERCCGQLILTPQIMTLA
KRRMIVMHPLPRVFEISVEIDSDPRAAYFRQAEYGMYVRMALLAMVLGRN
NT seq 6813 nt   +upstreamnt  +downstreamnt
atggcggagataaccatgctgccgaacgaggaagctatcgtcgcattgccgagcgaagta
cggaagcaagagttgagtgaatatagaccgccgacggcttacctggtgctggaggatggg
acaatctttcccggccacaagttcggtgcggatgtgagcgtagatggtgaggtcgtgttt
cagacgggtatggtaggttatccggaatcgatgaccgacccgtcgtatcatggccagata
ctggtgctaacgtatccgttgattggcaactacggcatcccggatgcggatttggatgag
tgtgggctaatgcggcactttgagtcgaacaaccgcatatggactgctgggctggttgtg
agtgaaatatgccacgaaccatcgcactggcgcagtaagctaacgctgtcaagctggatg
tggaggcatggtgtgccgggaattagtggaatagatacgcgagcgttgactaaaaagata
cgcgaaaatggcactattctaggaaagattgttcaatcacgtgtcttgtcgattgccggt
ctcaactttagcaatcaaaacttgcgaaacctggtcgcggaggtatcattggctcagccg
cgcacctacaacgaatcaggttcgccccgaattttggcaatagattgtggcttaaagcta
aatcaagtgcgttgcttcgttagccgtggtgcacggttggatgtggtaccgtggaatgca
cgaccgaacccggacgagtacgatgggctgtttctttcgaacggtcccggcgatccggag
atgtgccgggaggtggtggaaaatctgcggagtttgctcaacatgaagacggcgaagcca
atctttggcatctgtctcgggcatcagatcctctcgacggcggccggctgtcgtacgttt
aagatgcgctacggtaatcggggtcacaacctgccctgtatgcatcttggcactaggcga
tgctatatgacgtcgcaaaatcatggttttgcggtcgattccaatcagatgccggtagga
tgggaggagctgtttactaacctgaacgatggtacgaacgagggtattgtgcatcagact
aagccgtactttagtgtgcagttccatccggaacatacggctggtccggcagatttggag
gtgttgttcgatgtgtttcttgaggtggtgagtgagtacaagcgagagcctaagaaacag
cacgtgtcggtaaaggaccgtttgaacgagcgactgcaatacgtaccaccggtaccgatc
gatctggagcgtcccaagaaggtgttaatattgggatcgggtggattgtctatcgggcag
gctggagagttcgattactctggatcgcaggcgatcaaggcactgaaggaggaacgcatt
caaacggtcctgatcaacccaaacattgcaaccgttcagacttccaaggggttggcggat
aaggtgtactttctaccgttgactcggtattacgtggagaaggtaatcaaggcagaaaga
cccggcggtgtactgttaacgtttggtggccagaccgctttgaacgttggcattgagatg
gaacgggccggattgtttagtcggtacggtgtgaagattatgggtacaccgatcagttcc
atcattgaaaccgaggatcgcaagttgttcgccgaacgtgtggctgagattggtgagaag
gtcgcaccgtcagcagcggtatactccgtatcggaagcactcgatgcggcggatacgatc
ggctatcccgtaatggcacgtgccgcattctcgctcggtggtcttggttcgggttttgcg
agcaacgcggaagaactgaaggcactagcgaaccaagctttggcacattccaatcagctc
atcattgataagtcgctcaagggctggaaggaggtagagtacgaggtggtgcgcgatgcc
tacgacaactgtatcaccgtgtgcaacatggagaatgtcgatccgctgggcattcacacg
ggagaaagtattgtggtggcaccgtctcagacactttccaaccgggagtacaacctgttg
cgctccacagcgatacgtgtcatacggcactttggtgtagttggggagtgtaacatccag
tacgcgttgaatccggaatcggaagagtactacatcattgaggtgaatgcacgcctgtcg
agaagttccgcgttggccagtaaggcaactgggtatccgttggcgtacgtggcggcaaag
ttggcgctggcgataccgctcccagacatccgtaactcggtgaccggtgtgacgacggcc
tgctttgagccgagtctcgattactgtgtggtgaagatgccacgctgggatttggcgaag
tttgcacgcgttagcaagaatattgggagctccatgaagagtgtcggcgaagtaatggcg
attgggcgtaccttcgaggaagcgttccagaaggcactgcggatggtggacagtgtgaat
gggttcgatccttacctgaagccggtgaatgagcaggagctggagcaacccaccgacaag
cgtatgttcgtgttggctgctgccctgaaggcccgctacacggtggaacagatctacgag
ctgaccaagatagatcgttggtttttgcgcaagctgaaaggtatcatcgactttaccgat
gagctggaagagctcgagcacggttgcgtaccggaggcagcgatgttgcgtgaagcaaaa
cggcttggcttttccgatcgtatgattgcgcagtgcgttaaaagtaccgagctggcggta
cggatgcagcgtaaggaacttggcgtattacccttcgtgaaacagattgatacagtggcg
ggtgagtggcctgcctcgactaactatctctacctgacgtacagtgccaccgaaaacgat
gtcgagttcccgggacagtacacgatggtgatcggttcgggtgtgtatcggatcggcagc
tcggtcgagttcgattggtgtgccgtcgggtgtttgaaggagttacgccgattaaatcac
aaaaccatcatggtgaactacaatcccgaaacggtcagcacggattacgatatgtgcgat
cggctgtactttgaggaaatttcgttcgaagtcgtgatggatatttacgatgcggagcaa
ccgatgggtataattctttcgatgggtggccaactgccgaacaacatcgcgatggatctg
catcggcagcaggcacgcattttgggcacgtcacccgaatcggtcgatagtgccgaaaat
cggttcaagttttcgcgcaagctcgaccgcaaggggatttctcaaccgcgctggaaggag
ttgacgaatctggaatcggcgatcgagttttgtgaggaggtcggatatccgtgtctggta
cggccttcctatgtgctgtccggtgccgccatgaacgtagcctactcaaaccaggacctc
aagacgtacctgaagcacgcgtccgacgtcagcaaagagcatccggtggtgatctcgaag
tttctggtcgaggcaaaagaaatcgatgtggatgcagttgcggcggacggtgtcattctg
tgcatggccgtgtccgaacacgtggagaacgctggtgtacattcgggtgatgcgacactc
gtgacaccaccgcaagacatcaaccgggaaacgctggagcgcatcaaggagatagcccga
gacattgccgacctgctggatgtaacgggtccgttcaatatgcagctgattgcgaaaaat
aacgagctgaaggtgatcgagtgtaatgtgcgcgtgtcgcgctcgttcccgttcgtgtcg
aagacgcttgacttcgactttgtggcactggctacgcgggtcatcgtgggacatacggat
attgagcctgtggaggtgatgcatggtcgcgggctggttggtgtaaaggtgccccagttc
agcttctcccgattggctggagctgacgtgatgttgggtgtggagatggcatcaactggt
gaggttgcctgctttggggagaatcgctacgaagcctacctcaaggctatgatgtcaacc
ggattccaaataccgaagaagtcgatactactcagtattggaagttacaagcacaaaatg
gaactcttaccatcgatacgtatactcgagaagatgggctacaagctgtatgcgtcaatg
ggcacgggtgacttttataccgaacacggcgttgaggtcgagagcgtacagtggacgttc
gattcgtttgccgcagaggacaatggcaacggtgctggaagtgagctgcgccatctggcg
gaatatctcgccaacaagcagtttgatctggtgatcaacccaccgatgagtggtggcggc
gctcgtcgggtagcctgcttcatgacgcacggttaccgtacccgacggttggccgtcgat
tactccatcccgctcgtgacggatgtgaagtgtgcgaaattgctggtagcggcaatgcaa
cggatcggtggtgcaccgtcgatgaagacacatatcgactgtatgtcgtcccggttgatg
gtaaagctgcccggctttattgatgtgcatgtgcatctgcgggaaccgggcgcaccgcat
aaggaaacttttgcgacgggtacggcagcggcccttgccggtggtataacgatggtactg
gcgatgccgaacacccaaccggctatagttgatcggggagcgttccagcaagcggtggaa
ctagcacagaaaggtgcacgatgtgactacgcactgtacgttggtgcgtcctctaccaac
ttcagcaccgttcatgagttggcgtctcaagcggccggtttgaagctttacctaaacgaa
acgttcacgacgttgcgattgaatggtctatccgtgtggcaggcgcatcttgccaactgg
ccaaagcgggcaccgctgtgtgtgcacgccgagcgggaaacgatggcggcggtactgctg
ttggcctcactcaccgaccgcccaatacacgtgtgccatgtagcgcgcaaagaggagata
ctgttgatcaaggcggccaaagagcgtggcctgaaggtgacatgcgaggtgtgcccgcat
catctcttcctatcgacggccgatctcgaccgtattggagcgggacggggtgaggtgcgt
ccggtattgtgtagcccggaagaccagcaagcgctctgggacaatctggacgtggtggat
gtgtttgcgacggatcatgcgccgcacgcccgggaggagaaggaatcggaacggccaccg
ccgggtttccccgggttggagacgattctcccgctgctgttgacggccgtcaccgaaggg
cggcttacgatggatgagctggtgaacaagttccacagtaatccacgccggatctttaac
ctgccggagcaaccgaacacgtacgttgagattgatctgagcgaggagtggattataccg
gaccgtccggcacattccaaggcgcactggacaccgtttgcggggatgcgcgtgaagggt
tgcgtgcatcgtgtggtgctgcgcggtgagacggcgtacgtcgatgggttggtgttggtc
aacccgggctatgggcagaacgtgcgcgaatggcacggtggaaagccaccgatggccggt
gccgcttcgatcgagcgtatcgatgtgctgaaccactcgatcggatccggttcgggtgtg
ggcttgcggaccgcagacctcgaaccggacctgcaaacgaacgaagcattctatcagctg
ctctcgccggacggtactaatgcgcacgtgaagcagctcggcgtacactttgccggggag
caatcggggatgcgttcggcgtcgccactcccaccgaggatacggtgcgattcgaccggc
aatcaatctgtggtcggtaagctcgaaccaatctccatcaatactgggctgggtggggtg
cgtgaacgtcagctagcgggtcgtcacgtcctgacggtggatatgttcaccaaggagcat
ctgaacgaaatctttcacctggcgcaaacgatgaaatcacgcgtcgctaaggagcgactg
ttggacgatctattgcgcggaaaggtgatggtgtccatcttctatgaagtgagtacacgc
acgagctgtagctttgcagcggcaatgcagcgtctcggtggtcggatcgtacacatcgac
gaaacgtcctcatccgctaaaaagggcgaaacgctcgaggatagcatccaggtgattgct
ggttatgctgatgtagttgtactgcgacatccattgcccggagcggttacgcgcgctgcc
cagcattgccgtaagccactaatcaacgcgggcgatggtgttggagaacatccaacacaa
gcactgctggatatatttaccatccgcgaggaaatcggtacggtgaacggtttaacgatc
acgatggtgggtgatctgaaacatggccgtaccgtccactcactggcacggctgctgacg
atgtacaacgtgaatttgcgctacgtttgcccggccgggctcgagatgccgagccacatt
aagcagtacatcgacaagaagggtatctcccagcgtcagtacgactcgctcgagacggct
attattgatacggatgtgctgtatatgacacggatccagcgtgagcggtttgaaagtgag
caggagtacgagaggtgttgcggacagctgatactaacgccccaaattatgacattggcc
aagcgtcgcatgatcgtgatgcacccattgccgcgcgtcttcgaaatcagtgtggagatt
gatagcgatcccagggcggcatacttccggcaggcggaatatggaatgtacgtgcgtatg
gcactgctagcgatggtgttgggacgaaactga

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