KEGG   Actinomyces israelii: NCTC12972_00407
Entry
NCTC12972_00407   CDS       T06659                                 
Symbol
ilvC
Name
(GenBank) Ketol-acid reductoisomerase
  KO
K00053  ketol-acid reductoisomerase [EC:1.1.1.86]
Organism
air  Actinomyces israelii
Pathway
air00290  Valine, leucine and isoleucine biosynthesis
air00770  Pantothenate and CoA biosynthesis
air01100  Metabolic pathways
air01110  Biosynthesis of secondary metabolites
air01210  2-Oxocarboxylic acid metabolism
air01230  Biosynthesis of amino acids
Module
air_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
air_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:air00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    NCTC12972_00407 (ilvC)
  09108 Metabolism of cofactors and vitamins
   00770 Pantothenate and CoA biosynthesis
    NCTC12972_00407 (ilvC)
Enzymes [BR:air01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.86  ketol-acid reductoisomerase (NADP+)
     NCTC12972_00407 (ilvC)
SSDB
Motif
Pfam: IlvN IlvC 2-Hacid_dh_C F420_oxidored NAD_binding_2 AdoHcyase_NAD Mur_ligase CoA_binding NAD_binding_7 Oxidored_nitro FMO-like GFO_IDH_MocA ApbA
Other DBs
NCBI-ProteinID: VEG53048
LinkDB
Position
1:480981..482012
AA seq 343 aa
MAAEKFYDADADLSIIQGKKVAVIGYGSQGHAHALNLRDSGVEVVVGLREGSSSVAKAEE
AGLPVKPVAEAVAWADVVVVLAPDQVQARLYQDEIEPSIRPGAALLFSHGFNIHFGYIKP
AAGIDVVMVAPKGPGHTVRRQFEEGRGVPVLVCVEQDATGQAWPLVLSYAKAVGGTRAGA
IKTTFREETETDLFGEQTVLCGGVSKLIEYGFETLVEAGYQPEMAYFEVCHELKLIVDLI
NEGGLSKQRWSCSDTAEYGDYVSGPRVITPDVKVHMQEVLADIQSGAFAKRFMDDQAAGA
PEFKQLRAQGEAHPIERTGREVRSMFAWRAEVDKDYTEGSVAR
NT seq 1032 nt   +upstreamnt  +downstreamnt
atggcagcagaaaagttctacgacgccgacgccgacctgtccatcattcagggcaagaag
gtagccgtcattggctacggctcacaggggcacgcccacgccctcaacctgcgtgactcc
ggggtggaggtggttgtgggcctgcgtgagggctccagctccgtagccaaggccgaggag
gcgggcctgcccgtcaagcccgtggccgaggccgtggcttgggccgacgtggtggtggtg
ctggcccctgaccaggtgcaggccaggctgtaccaggatgagatcgagcccagtatcagg
cccggggccgccctgctgttctcccacggcttcaacattcacttcggctacatcaagccc
gctgccgggatcgacgtggtcatggtggcgcctaaggggccgggccacacggtgcgccgc
cagttcgaggaggggcggggcgtgccggtgctcgtctgtgtggagcaggacgccaccggg
caggcctggccgcttgtgctgtcttacgccaaggcggtaggtggtacccgggcgggtgcc
atcaagacgaccttccgtgaggagactgagactgacctgtttggggagcagaccgtgctg
tgcggtggcgtctccaaactgatcgaatatggctttgagacgctggtggaggccggttac
cagccagagatggcctacttcgaggtgtgccacgagctcaagctgattgtggaccttatc
aatgagggtggcttgtccaagcagcgctggtcttgctccgacactgctgagtacggcgac
tatgtctctgggccgcgcgtgatcaccccggatgtcaaggtgcatatgcaggaggtgctg
gcggacatccagagcggggcctttgccaagcgtttcatggatgaccaggctgctggggcg
cccgagttcaagcagttgcgtgcccagggggaggctcacccgattgagaggacgggccgg
gaggtgcgttccatgtttgcctggcgcgctgaggtggacaaggactacaccgagggctcc
gtggcccgctga

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