KEGG   PATHWAY: alim00330
Entry
alim00330                   Pathway                                
Name
Arginine and proline metabolism - Austrofundulus limnaeus (annual killifish)
Class
Metabolism; Amino acid metabolism
Pathway map
alim00330  Arginine and proline metabolism
alim00330

Module
alim_M00015  Proline biosynthesis, glutamate => proline [PATH:alim00330]
alim_M00047  Creatine pathway [PATH:alim00330]
alim_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:alim00330]
alim_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:alim00330]
alim_M00970  Proline degradation, proline => glutamate [PATH:alim00330]
alim_M00972  Proline metabolism [PATH:alim00330]
Other DBs
GO: 0006525 0006560
Organism
Austrofundulus limnaeus (annual killifish) [GN:alim]
Gene
106511146  [KO:K00128] [EC:1.2.1.3]
106511366  aldh4a1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
106511506  aldh7a1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
106511689  p4ha1; prolyl 4-hydroxylase subunit alpha-1 isoform X1 [KO:K00472] [EC:1.14.11.2]
106512193  [KO:K00128] [EC:1.2.1.3]
106513569  [KO:K00274] [EC:1.4.3.4]
106513655  ckmt2; creatine kinase S-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
106514045  sms; spermine synthase [KO:K00802] [EC:2.5.1.22]
106514456  [KO:K00318] [EC:1.5.5.2]
106516361  [KO:K00657] [EC:2.3.1.57]
106516596  oat; ornithine aminotransferase, mitochondrial [KO:K00819] [EC:2.6.1.13]
106516924  l3hypdh; trans-3-hydroxy-L-proline dehydratase [KO:K18384] [EC:4.2.1.77]
106516993  [KO:K12657] [EC:2.7.2.11 1.2.1.41]
106517042  smox; spermine oxidase isoform X1 [KO:K12259] [EC:1.5.3.16 1.5.3.-]
106518751  odc1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
106519249  gamt; guanidinoacetate N-methyltransferase [KO:K00542] [EC:2.1.1.2]
106519437  [KO:K00318] [EC:1.5.5.2]
106519449  nos1; nitric oxide synthase, brain [KO:K13240] [EC:1.14.13.39]
106521389  prodh2; probable proline dehydrogenase 2 isoform X1 [KO:K11394] [EC:1.5.5.3]
106521451  pycr1; pyrroline-5-carboxylate reductase 1, mitochondrial [KO:K00286] [EC:1.5.1.2]
106521688  dao; D-amino-acid oxidase [KO:K00273] [EC:1.4.3.3]
106522195  [KO:K00933] [EC:2.7.3.2]
106522778  ckm; creatine kinase M-type [KO:K27382]
106522935  sat2; diamine acetyltransferase 2 [KO:K00657] [EC:2.3.1.57]
106523169  [KO:K27382]
106523457  [KO:K00128] [EC:1.2.1.3]
106524201  pycrl; pyrroline-5-carboxylate reductase 3 [KO:K00286] [EC:1.5.1.2]
106525528  p4ha2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
106525848  lap3; cytosol aminopeptidase [KO:K11142] [EC:3.4.11.1 3.4.11.5]
106526131  [KO:K00657] [EC:2.3.1.57]
106526419  srm; spermidine synthase [KO:K00797] [EC:2.5.1.16]
106526533  [KO:K12657] [EC:2.7.2.11 1.2.1.41]
106526791  aldh16a1; aldehyde dehydrogenase family 16 member A1 [KO:K00128] [EC:1.2.1.3]
106527006  aldh2; aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
106527178  [KO:K00149] [EC:1.2.1.47 1.2.1.3]
106527260  ckb; creatine kinase B-type [KO:K00933] [EC:2.7.3.2]
106528226  [KO:K01476] [EC:3.5.3.1]
106528227  [KO:K00472] [EC:1.14.11.2]
106528295  got1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
106528325  [KO:K00128] [EC:1.2.1.3]
106528598  aoc1; amiloride-sensitive amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
106528662  [KO:K00933] [EC:2.7.3.2]
106529074  agmat; agmatinase, mitochondrial [KO:K27001]
106529303  aldh9a1; 4-trimethylaminobutyraldehyde dehydrogenase [KO:K00149] [EC:1.2.1.47 1.2.1.3]
106529731  p4ha3; prolyl 4-hydroxylase subunit alpha-3 [KO:K00472] [EC:1.14.11.2]
106531843  sat1; diamine acetyltransferase 1 [KO:K00657] [EC:2.3.1.57]
106532191  got2; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
106533319  arg2; arginase-2, mitochondrial [KO:K01476] [EC:3.5.3.1]
106533442  [KO:K00274] [EC:1.4.3.4]
106533854  [KO:K00286] [EC:1.5.1.2]
106533979  gatm; glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
106534150  amd1; S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
106535012  [KO:K00274] [EC:1.4.3.4]
106535632  [KO:K00933] [EC:2.7.3.2]
106536426  [KO:K08660] [EC:3.4.13.18]
106537034  hoga1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial [KO:K18123] [EC:4.1.3.16]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
C20560  N1-(3-Aminopropyl)agmatine
C22886  N1-[(S)-3-amino-3-carboxypropyl]agmatine
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
alim00020  Citrate cycle (TCA cycle)
alim00220  Arginine biosynthesis
alim00250  Alanine, aspartate and glutamate metabolism
alim00260  Glycine, serine and threonine metabolism
alim00270  Cysteine and methionine metabolism
alim00310  Lysine degradation
alim00410  beta-Alanine metabolism
alim00470  D-Amino acid metabolism
alim00480  Glutathione metabolism
alim00630  Glyoxylate and dicarboxylate metabolism
alim00650  Butanoate metabolism
alim00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   

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