Ailuropoda melanoleuca (giant panda): 100482519 Help Entry 100482519         CDS       T01329                                  Symbol ADCY5 Name (RefSeq) adenylate cyclase type 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism aml  Ailuropoda melanoleuca (giant panda) Pathway aml00230   Purine metabolism aml01100   Metabolic pathways aml01522   Endocrine resistance aml04015   Rap1 signaling pathway aml04022   cGMP-PKG signaling pathway aml04024   cAMP signaling pathway aml04062   Chemokine signaling pathway aml04072   Phospholipase D signaling pathway aml04081   Hormone signaling aml04082   Neuroactive ligand signaling aml04114   Oocyte meiosis aml04211   Longevity regulating pathway aml04213   Longevity regulating pathway - multiple species aml04261   Adrenergic signaling in cardiomyocytes aml04270   Vascular smooth muscle contraction aml04371   Apelin signaling pathway aml04540   Gap junction aml04611   Platelet activation aml04713   Circadian entrainment aml04714   Thermogenesis aml04723   Retrograde endocannabinoid signaling aml04724   Glutamatergic synapse aml04725   Cholinergic synapse aml04726   Serotonergic synapse aml04727   GABAergic synapse aml04728   Dopaminergic synapse aml04750   Inflammatory mediator regulation of TRP channels aml04911   Insulin secretion aml04912   GnRH signaling pathway aml04913   Ovarian steroidogenesis aml04914   Progesterone-mediated oocyte maturation aml04915   Estrogen signaling pathway aml04916   Melanogenesis aml04918   Thyroid hormone synthesis aml04921   Oxytocin signaling pathway aml04923   Regulation of lipolysis in adipocytes aml04924   Renin secretion aml04925   Aldosterone synthesis and secretion aml04926   Relaxin signaling pathway aml04927   Cortisol synthesis and secretion aml04928   Parathyroid hormone synthesis, secretion and action aml04934   Cushing syndrome aml04935   Growth hormone synthesis, secretion and action aml04970   Salivary secretion aml04971   Gastric acid secretion aml04972   Pancreatic secretion aml04976   Bile secretion aml05012   Parkinson disease aml05030   Cocaine addiction aml05031   Amphetamine addiction aml05032   Morphine addiction aml05034   Alcoholism aml05163   Human cytomegalovirus infection aml05166   Human T-cell leukemia virus 1 infection aml05200   Pathways in cancer aml05207   Chemical carcinogenesis - receptor activation aml05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:aml00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100482519 (ADCY5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100482519 (ADCY5)    04371 Apelin signaling pathway     100482519 (ADCY5)    04072 Phospholipase D signaling pathway     100482519 (ADCY5)    04024 cAMP signaling pathway     100482519 (ADCY5)    04022 cGMP-PKG signaling pathway     100482519 (ADCY5)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     100482519 (ADCY5)    04081 Hormone signaling     100482519 (ADCY5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     100482519 (ADCY5)   09144 Cellular community - eukaryotes    04540 Gap junction     100482519 (ADCY5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100482519 (ADCY5)    04062 Chemokine signaling pathway     100482519 (ADCY5)   09152 Endocrine system    04911 Insulin secretion     100482519 (ADCY5)    04923 Regulation of lipolysis in adipocytes     100482519 (ADCY5)    04912 GnRH signaling pathway     100482519 (ADCY5)    04913 Ovarian steroidogenesis     100482519 (ADCY5)    04915 Estrogen signaling pathway     100482519 (ADCY5)    04914 Progesterone-mediated oocyte maturation     100482519 (ADCY5)    04921 Oxytocin signaling pathway     100482519 (ADCY5)    04926 Relaxin signaling pathway     100482519 (ADCY5)    04935 Growth hormone synthesis, secretion and action     100482519 (ADCY5)    04918 Thyroid hormone synthesis     100482519 (ADCY5)    04928 Parathyroid hormone synthesis, secretion and action     100482519 (ADCY5)    04916 Melanogenesis     100482519 (ADCY5)    04924 Renin secretion     100482519 (ADCY5)    04925 Aldosterone synthesis and secretion     100482519 (ADCY5)    04927 Cortisol synthesis and secretion     100482519 (ADCY5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100482519 (ADCY5)    04270 Vascular smooth muscle contraction     100482519 (ADCY5)   09154 Digestive system    04970 Salivary secretion     100482519 (ADCY5)    04971 Gastric acid secretion     100482519 (ADCY5)    04972 Pancreatic secretion     100482519 (ADCY5)    04976 Bile secretion     100482519 (ADCY5)   09156 Nervous system    04724 Glutamatergic synapse     100482519 (ADCY5)    04727 GABAergic synapse     100482519 (ADCY5)    04725 Cholinergic synapse     100482519 (ADCY5)    04728 Dopaminergic synapse     100482519 (ADCY5)    04726 Serotonergic synapse     100482519 (ADCY5)    04723 Retrograde endocannabinoid signaling     100482519 (ADCY5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100482519 (ADCY5)   09149 Aging    04211 Longevity regulating pathway     100482519 (ADCY5)    04213 Longevity regulating pathway - multiple species     100482519 (ADCY5)   09159 Environmental adaptation    04713 Circadian entrainment     100482519 (ADCY5)    04714 Thermogenesis     100482519 (ADCY5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100482519 (ADCY5)    05207 Chemical carcinogenesis - receptor activation     100482519 (ADCY5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100482519 (ADCY5)    05163 Human cytomegalovirus infection     100482519 (ADCY5)   09164 Neurodegenerative disease    05012 Parkinson disease     100482519 (ADCY5)   09165 Substance dependence    05030 Cocaine addiction     100482519 (ADCY5)    05031 Amphetamine addiction     100482519 (ADCY5)    05032 Morphine addiction     100482519 (ADCY5)    05034 Alcoholism     100482519 (ADCY5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100482519 (ADCY5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100482519 (ADCY5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100482519 (ADCY5) Enzymes [BR:aml01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100482519 (ADCY5) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AC_N Guanylate_cyc Adcy_cons_dom TBK1_ULD GBR2_CC Motif Other DBs NCBI-GeneID:  100482519 NCBI-ProteinID:  XP_034526603 LinkDB All DBs Position 1:complement(65131939..65275026) Genome browser AA seq 1095 aa AA seqDB search GKGRAVDELEAGAVDGDEGSGDGGSSAESGAGPGAVLSLGACCLALLQIFRSKKFPSDKL ERLYQRYFFRLNQSSLTMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILVMAV LCNRAAFHQDHMGLACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVR MRAAVLSGVLLSALHLAIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQ AFQETRECIQARLHSQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHD NVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGL PEARADHAHCCVEMGMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWS NDVTLANHMEAGGKAGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCT QKRKEEKAMIAKMNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNA QESANPEDEVDEFLGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVA CASLVFLFICFVQITIVPHSVFMLSFYLTCFLLLTLVVFVSVIYSCVKLFPTPLQTLSRK IVRSKMNSTLVGVFTITLVFLSAFVNMFTCNSKDLFGCLADEHNISTSQVNACHVVESAT NYSLGDERGVCSSPWPNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELTYVLI VEVPRVTLFDNADLLVTANAIDFNNNGTSQCPEHATKVALKVMTPIILSVFVLALYLHAQ QVESTARLDFLWKLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQS CECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIG STYMAASGLNDSTYDKVGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVA GVIGARKPQYDIWGNTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGK GEMMTYFLNGGPPLS NT seq 3288 nt NT seq  +upstreamnt  +downstreamnt ggcaagggccgcgcggtggacgagctggaggccggcgccgtcgatggcgacgaagggtcc ggggatggcggcagctcggcagaatcaggcgcggggcccggcgcagtgctgtcgctgggt gcctgctgcctggcgctgctgcagatattccgctccaagaagttcccgtcggacaagctg gagcggctgtaccagcgctacttcttccgtctgaaccagagcagcctcactatgctcatg gccgtgctggtgctcgtgtgcctcgtcatgttggccttccacgcggcgcggcccccgctc cagctgccctacctggcagtgctggcggctgcggtaggtgtcatcctcgtcatggctgtg ctctgtaaccgcgccgccttccaccaggaccacatgggcctggcctgctacgcgctcatc gccgtggtgctggccgtccaggtggtgggcctgttgctgccccagccgcgcagcgcctcc gagggcatctggtggaccgtgttcttcatctacaccatctacacgctgctgcctgtgcgc atgcgggccgcggtactcagtggtgtgctcctgtctgccctccacctggccatcgccctg cgcaccaacgcccaggaccagttcctgctgaagcagcttgtctccaatgtcctcattttc tcctgcaccaacatcgtgggtgtttgcacccactacccggctgaggtctcccagagacag gccttccaggagacccgggagtgcatccaggcacggctccactcacaacgggagaaccag caacaggagcggctcctgctgtctgtcctgccccgtcatgttgccatggagatgaaagca gacatcaatgccaagcaggaggatatgatgttccataagatttacatccagaaacacgac aacgtgagcatcctgtttgctgacatcgagggcttcaccagcctggcatcccagtgcact gcccaggagctggtcatgaccctcaacgagctcttcgcccgattcgacaagctggctgcg gagaatcactgtttacgtattaagatcctgggggattgttattactgtgtctctgggctg cctgaagcgagggctgaccacgcccactgctgcgtggagatgggcatggacatgattgag gccatctcgttggtccgggaggtgacaggggtgaacgtgaacatgcgcgtgggaattcac agcgggcgagtacactgcggtgtccttggtctcaggaagtggcaattcgacgtctggtct aatgacgtcacgctggccaaccacatggaagctggaggcaaggcagggcgcatccacatc accaaggccacactcaactacctgaacggggactacgaagtggagccgggctgtgggggc gagcgtaacgcctacctcaaggagcacagtatcgagaccttcctcatcctgcgctgcacc cagaagcggaaagaagaaaaggccatgatcgccaagatgaatcgccagagaaccaactcc attgggcacaacccgccccactggggggccgagcgtcccttctacaaccacctggggggc aaccaggtgtccaaggagatgaagcggatgggcttcgaagaccccaaggacaagaacgcc caagaaagtgcaaaccctgaggacgaagtggatgaatttctgggccgtgccattgacgcc aggagcattgacaggctgcggtctgagcatgtccgcaagttcctcttgaccttcagggag cctgacttagagaagaagtactccaagcaggtggatgaccgattcggtgcctacgtggca tgtgcctcgcttgtcttcctcttcatctgctttgtccagatcaccatcgtgccccactcc gtgttcatgttgagtttctacctgacctgtttcctgctgctgacgttggtggtatttgtg tccgtgatctattcctgcgtgaagctcttccccaccccactgcagaccctctccaggaag attgtgcggtccaagatgaatagcactctggttggcgtgttcaccatcactctcgtgttc ctctcggctttcgtcaacatgttcacatgtaactccaaggacctgttcggctgcctggcg gacgagcacaacatcagcaccagccaggtcaacgcgtgccacgtggtggagtcggccacc aactacagcctgggggacgagcggggcgtctgcagcagcccgtggcccaactgtaacttc cctgagtacttcacctacagcgtgctgctcagcctgctggcctgctccgtgttcctgcag atcagctgcattgggaagctggtgctcatgctggccattgagctcacgtacgtgctcatc gtcgaggtgccccgagtcacgctctttgacaatgccgacctgctggtcaccgccaatgcc atagacttcaacaacaacgggacctcccagtgccctgagcatgcgaccaaggtggcactg aaggtgatgacgcccatcatcctctccgtctttgtgctggccctgtacctgcacgcccag caagtggagtccactgcccgcctggacttcctctggaaactgcaggccacggaggagaaa gaggagatggaggagctgcaggcctacaaccggcggctgttgcacaacatcctgcccaag gacgtggctgcccactttctggcccgcgagcggcgcaacgacgagctctactaccagtcg tgcgagtgcgtggctgtcatgttcgcctccatcgccaacttctccgagttctacgtggag ctggaggccaacaatgagggcgtcgagtgcctgcggctgctcaatgagatcatcgccgac tttgatgagatcatcagtgaggatcggttcaggcagctggagaagatcaagaccatcggc agcacctacatggccgcctcaggcctcaatgactctacgtatgacaaggtgggcaagacc cacattaaagccctggccgacttcgccatgaagctcatggaccaaatgaagtacatcaat gaacactccttcaacaacttccagatgaagattgggctcaacatcggccctgtggtggcc ggggtgatcggggctcgcaagccgcagtacgacatctggggcaatacggtgaacgtggcc agccgcatggacagcaccggtgtgcccgaccgcatccaggtcaccacagacatgtaccag gtgctggctgccaacacataccagctggagtgcaggggtgtggtcaaggtcaagggcaaa ggcgagatgatgacctacttcctcaacggggggcccccgctcagttag

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