Amycolatopsis orientalis: SD37_05095
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Entry
SD37_05095 CDS
T06703
Name
(GenBank) 2,3-dihydroxybenzoate-AMP ligase
KO
K20423
2-hydroxy-7-methoxy-5-methyl-1-naphthoate---CoA ligase [EC:
6.2.1.43
]
Organism
aori
Amycolatopsis orientalis
Pathway
aori01059
Biosynthesis of enediyne antibiotics
aori01100
Metabolic pathways
aori01110
Biosynthesis of secondary metabolites
Module
aori_M00830
Neocarzinostatin naphthoate moiety biosynthesis, malonyl-CoA => 2-hydroxy-5-methyl-1-naphthoate => 2-hydroxy-7-methoxy-5-methyl-1-naphthoyl-CoA
Brite
KEGG Orthology (KO) [BR:
aori00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01059 Biosynthesis of enediyne antibiotics
SD37_05095
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins [BR:
aori01008
]
SD37_05095
Enzymes [BR:
aori01000
]
6. Ligases
6.2 Forming carbon-sulfur bonds
6.2.1 Acid-thiol ligases
6.2.1.43 2-hydroxy-7-methoxy-5-methyl-1-naphthoate---CoA ligase
SD37_05095
Polyketide biosynthesis proteins [BR:
aori01008
]
Polyketide tailoring proteins
Others
SD37_05095
BRITE hierarchy
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GFIT
Motif
Pfam:
AMP-binding
AMP-binding_C
GH3
Motif
Other DBs
NCBI-ProteinID:
ANN15097
UniProt:
A0A193BSB7
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All DBs
Position
complement(1036896..1038569)
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AA seq
557 aa
AA seq
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MPGSAGRSTGTGVVPWPRSVADRYFAEGYWEGRSLGTQLAETARKYPDEVCLVDGEVRLT
FGELLAKADGAAIRMSAAGIGADDRVVIQLPNCWEFVVTTVACLRLGAVPVWTMPQFREH
EIGGILANAEAGAIVVPDVHKGFDHQALAREVLPDGLVFVVGEDVHPGNIDLRALFVADE
PAEVSQALDAAAPNGDAVATFLLSGGTTGLPKLIPRSGNDLSYMIKTASEICRFGPDTSY
LVVLPLGHGFANTGPGILGALLSGGRVVIAPSPAPHQALPLIESERITATSAVPAILHRW
IEYLDSAPGFDLSTLEMIQIGAAKLDPSLAAQVRPKLGCTLQQVFGMGEGLLCLTRLDDP
DELILHTQGKPISPGDELRLVDEEGVPVAPGEPGLLLVRGPYTTRGYYRSPELNARSFVD
GGWYNTGDIVRLTPEGYLVVSGREKDVINRGGEKINAEEIETFALEVSGVEHAAAVAMPD
AELGEVVCLYVVATRPVALQDVHTLMLAAGAARFKLPERLVVVDALPATGIGKVDKKALR
ADIASRLTEELKGTIAA
NT seq
1674 nt
NT seq
+upstream
nt +downstream
nt
atgccgggatcagcgggacggtcgaccgggacgggagtcgtgccgtggccgagaagcgtc
gcggaccgctatttcgccgagggctattgggaaggccggtcgctggggacgcagctggcc
gaaaccgcgcgcaagtacccggacgaggtctgcctcgtcgacggggaggtgcgactgacg
ttcggtgagctgctggcgaaggccgacggagcggcgatccggatgagcgcggccgggatc
ggcgccgatgaccgggtcgtcatccagttgccgaactgctgggagttcgtcgtcaccacg
gtcgcctgtctccggctcggcgccgttccggtgtggacgatgccgcagttccgcgagcac
gagatcggcggcatcctcgccaacgccgaagcgggcgcgatcgtcgtcccggatgtccac
aaaggattcgaccatcaggcgctggcccgtgaagtcctgccggacgggctcgtgttcgtg
gtcggcgaggacgtccaccctggcaacatcgacctccgggcgttgttcgtcgcggacgaa
cccgccgaagtctcgcaagccctcgacgcggccgccccgaacggggacgccgtcgcgacc
ttcctgctctccggcgggacgaccgggctgccgaagctgatcccgcgcagtggcaacgac
ttgagctacatgatcaagaccgcctcggagatctgccggttcggcccggacacctcgtac
ctggtggtgctgccgctcggacacggattcgccaataccggtccgggtatcctgggcgcg
ctgctgtccggcggccgggtcgtcatcgcgccgtccccggcgccgcaccaggcgctgccg
ttgatcgaaagcgagcggatcaccgcgacttccgcggtgccggcgatcttgcatcgctgg
atcgaatacctggactccgcccccggattcgatctgtccactttggaaatgatccagatc
ggcgcggccaagctcgatccctcgctggcggcgcaggtgcggccgaagctcggctgcacg
ctgcagcaggtcttcgggatgggtgaaggactcctgtgcctgacccggctcgacgatccg
gacgagctgatcctgcacacccagggcaaaccgatctcgcccggggacgaactccggctc
gtggacgaagaaggcgtcccggtggcgcctggtgagcccgggttgctgctggtccgcggc
ccgtacacgactcgcggttactaccgctcccccgagctgaacgcgcgctcgttcgtcgac
ggcggctggtacaacaccggcgacatcgtccggctgacgcccgagggctatctggtggtc
tccgggcgcgagaaggacgtcatcaaccgcggcggggagaagatcaacgccgaggagatc
gagaccttcgcgctggaggtatccggtgtcgagcacgcggccgcggtcgcgatgccggac
gcggaactcggcgaggtcgtctgcctctatgtggtcgccacccggccggtggccctgcag
gacgtgcacaccctgatgctcgccgcgggcgccgcgcggttcaagctgccggagcggctg
gtcgtcgtcgacgccttgcccgccacgggaatcgggaaggtcgacaagaaggcgctgcgg
gccgacatcgcgtcacgcctgactgaggagctgaagggaaccatcgccgcatag
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