Anguilla rostrata (American eel): 135250381 Help Entry 135250381         CDS       T10705                                  Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism arot  Anguilla rostrata (American eel) Pathway arot04020   Calcium signaling pathway arot04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:arot00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     135250381    04020 Calcium signaling pathway     135250381  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:arot04040]     135250381 Ion channels [BR:arot04040]  Voltage-gated cation channels   Ryanodine receptor    135250381 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 Ins145_P3_rec SPRY MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_8 EF-hand_6 EF-hand_5 Motif Other DBs NCBI-GeneID:  135250381 NCBI-ProteinID:  XP_064182674 LinkDB All DBs Position 1:17687357..17814118 Genome browser AA seq 4891 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQCVASIQKENRKFCLTAEGLGNRLCYLEPTSEAKYVPP DLCICNFVLEQSLSVRALQEMLAKTGPNSEGRLIRKAAQGGGHRTLLYGHAILLRHSFSG MYLTCLKTSRSLTDKLSFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRIGDDLILVSVS TERYLHLSISNGNIQVDASFMQTLWNVHPTCSGSSVEEGYLLGGHVMRLFHGHDETLTIP GSDQSEEEQRIVNYEAGKAGAKARSLWRLEPLRISWSGSHIRWGQPFRLRHLTTGHYLAL TEDRGLVLQDREKSDTKSTAFCFRASKDKQDSSPKRDVEGMGVAEIKYGDSICFVLHVAS GLWLSYQAPDVKSSRLGPLKRRACLHVEGHMDDGLTLQRCQHEESRAARIIRNTTRLFSH FIRDLDSLRGKNRVAVALHIEEVLQTLNDLITYFQLPDAELEHEEKQIKLRSLKNRQNLF KQEGMLTLVSNCIDRLNLYNSAAHFGESAGEEAAGAWKDILNLLYELLAALIRGNRNNCT QFSQNLDWLVSKLERLESSSGILEVLHCILIESPEALNIIQRGHIKSIISLLYKHGRNHK ILDVLCSLCVCNGVAVRANQNLICDNLLPKRDLLLQTRLVNDVQSMRPNIFLGMSEGSAQ YRKWYYELMIDQVDHFLTSEPSHLRVGWANSKGYAPYPGGGEGWGGNGVGDDLYSYSFDG LHLWSGRIPRAVASISQHLLTSDDVVSCCLDLGAPSISFRINGQPVQGMFENFNTDGLFF PVVSFSAGVKVRFLLGGRHGDFKFLPPSGYAPCYEALLPKEKMRVEPVKEYKRDFDGVRD LLGTAQFMSQASFIPMPVDTSQIVLPPHLEKVRDKLAENIHELWGMNKIELGWSYGKMRD DNKRHHPCLVDFSKLPETEKNYNLQMSTETLKTLLALGCHVVHIHIDAEEDLKKMKLPKN YMMSNGYKPAPLELSDVKLTPGQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKSKRN PRLVPYALLDERTKKSNRDSLREAIRTLIGYGYNIDPPDQESAAHTSERLSIDKIRFFRV EQTYAVKTGRWYFEFEAVTGGDMRVGWARPGCRPDIELGMDDQAYVFDGFRGQRLHMGGR FFGRSWHAGDVVGCMINMEDKSMIFTLNGEILITNKGSELCFADFETEDGFIPVCSLGLS QTGRMNLGKDASTFKYYTMCGLQEGFEPFAVNMNRDVTMWFSKRLPTFVNVPKDHNHIQV TRIDGTIDSPPCLKVTHKTFGTQNSNADMVFCRLSMPVEFQTAFRSNPSIDMNGVHEDDS QKPKHRYPVKSLKHSEDGRRADYSSITMYYHSVRVFAGQDPSCVWVGWVTPDYHYYSNHF NLSKNRTVTVTLGDERGRVHESLRRSNCYMVWGGDIASASHTSGRSNVDLEIGCLIDLMT GLVNFSANGKELPTSYQVEPNSKLFPAVFVLPTSPNLFQFELAKIKNAMPLSSAIFKSEH KNPVPQCPPRLDVQTITSVLWSRMPNTFLKVETARVSERHGWVVQCLEPLQMMAVHIPEE NRCVDIMELSELDDLRKFHYHTLKLYCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLA GMLREGFYNVLISIHLETSKEARLMMNNEFIIPVTDETRSIRLFPDESKRHQPPGVGLST SLKPRFNFAPPCFISIKRDQHLSSPEIPLDILKEKAISMLTEAVQGGGHHIRDPVGGSVE FQFVPILKLIGTLLIMGILGSEDVQKILLLIDPNVFGERKEEEPEQATEKEDVTSNEEKA VEAGEEEAKDGKQPVKGLLEKRLPESVKRQMCELLHYFCDCELKHRIEAIVSFSDSFVSK LQYNQKFRYNELMQALNMSAAITARKTKEFRSPPQEQINMLLNFSMGEDCPCPEDIQEEL YEFHNELRLHCGIPIEEEEEEQDTSIKGRLLALVYKIKGPPQKTEENPTEEEQAAPTNLK ELISQTMVSWAQECHIQDPELVRVMFSLLRRQYDCVGELLRAMRKSYTISAASVKDTINL LASLGQIRSLLSVRMGKEEERLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVL GGDKSQEIAFPKMVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPAMRGSTP LDVAASSVMDNNGLALALEEPDLEKVVMYLAGCGLQSCPMLLAKGYPDIGWNPIEGERYL SFLRFAVFVNGESVEENSSVVVKLLIRRPECFGPALRGEGGNGLLAAMKEAIKISENPSM DLPSSAHGVSSVMPADGDEEEEVVHMGNAIMSFYSALIDLLGRCAPEMHLINKGKGEALR IRAILRSLVPTEDLVGIISIPLKMPIVNKDGTVTEPDMSASFCPDHKAPMVLFLDRVYGI EDQSFLLHLLEVGFLPDLRASASLDTEALSTTETALAMNRYIGSAMLPLLTRCASHFGGT EHYAALIDSTLHTIYRLSKGRSLTKAQRDAIEECLLAICKYLRPSMLQQLLRRLVFDVPL LTEYCKMPLKLLTNHYEQSWKYYCLPSGGGGFGMASEEELLLTKKLFWGIFDSLSQKKYE QELFKMAMPCLSAIAGALPPDYVDSSLSTTLEKQTSVDAHGNFDPRPISTANISLPEKLE YVANKYAEHSHEKWSAEKVTLGWKYGESIDEKVKTHPMMRPYKSLTDKEKEVYRWPVKES LKTMLAMGWNIERTKEGEAMFQQRESEKLRKISQSSQGNGFNPCPLDMSNVVLSRELQGM VEIVAENYHNIWAKKKKTELGSRGGGTHPLLVPYDTLTAKEKARDREKAQDLFRFLQVNG YAITRGLKDMEQDSSSMEKRFAYKFLKKLLKYVDSAQEFIAHLEAMATSGKKDKSPHEQE IKFFAKVLLPLIDQYFKNHSLYFLSSPSSNLGGSGYASNKEKEMLTSLFCKLAALVRHRI SLFGSDSATMVSCLHILAHTLDTRTVMKSGSELVKAGLRTFFENAAEDLEKTLENLKLGK FTHSRSQMKGVSQNINYTTVALLPILTALFEHITQYHFGVDLLLDDVQLSCYRILTSLYS LGTGKNIYVERQLPALGECLATLAGAMPVAFLEPHLNVHNPWSVFNTKTPRERAILSMPD SVEEMCPEMPRLDGLMKDINDMSESGARYTEMPHVIEVVLPMLCNYLSYWWEKGPENTSN GSSSSCCTTVTSEHLSVILGNILKILNSNLGIDEASWMKRIAVYAQPIISKARADLLRTH FLPTLEKLKKKTVKVVAEEELLKADSKGDTQEAELLILDEFAVLCRDLYAFYPMLIRYVD INRSRWLKEPDADSNALFKMVAEIFILWCKSHNFKREEQNFVVQNEINNLSFLTGDSKTK MSKSFLGKTGGQDQERRHKKRRGEFYSIQTSLIVAALKKLLPIGLNMCTPGDQELISLAK IRYSLKDTDEEVKDHLRQNLHLQEKSEDPAVRWQLNLYRDVVVKSDGPPDPERTVARVQS ISAAVFHLEQVEQPLRSKKCVWQKLLSKQRKRAVVACFRMAPLYNLPRHKNNNYFLNAYQ HYWLEKMHENTDYDSLLSMLTKVHKKVEEEEEEEAEVQPDPLHQLILHFSHNALTERSAL DEDPLYIAYADMMAKSCAENEEEEEEEGKEKTFEEKEMEKQKTLYQQARLHDRGAAEMVL QMISASKGRLGPMVTFTLKLGISVLNGGNVVVQQKMLDYLKEKRDVGFFKSLSGLMQSCS VLDLNAFERQNKAEGLGMVTEEGSVNVSERGSKVLQNDEFTKDLFRFLQLLCEGHNNDFQ NFLRTQTGNTTTVNIIISTVDYLLRLQESISDFYWYYSGKDVMDEPGQRNFSKALAVAKQ IFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSSQIELLKELLDLQ KDMVVMMLSLLEGNVVNGTIGKQMVDTLVESSSNVEMILKFFDMFLKLKDLTTSDSFKEF DPDSKGVISKKEFQKSMENQKQYTQSEIEFLLSCVEADENDMFNYEEFVERFHEPAKDIG FNVAVLLTNLSEHMPHDSRLAAFLDLAESVLNYFEPYLGRIEIMGGAKRIERVYFEISES SRTQWEKPQVKESKRQFIFDVVNEGGESEKMELFVNFCEDTIFEMQLASQISEPDAVERP EEDEDDAHSILEELEEEEEEHALESSSAFTIACVSMKKNLSHFRQQISVRNMRKQFKKFR KMSIREMIKGFFSFFWMIFTGLFRFMYNLVWGFFHILWTSMFGGGLVEGAKNMKVTDILG NMPDPTQFGIHGDVLESEKLETSESASGAEMVQMAKGDQSEVDLMTELMNIPPKREGGKH GPEPGLGDVSEIVGVDAPSLASAVKQKKAQKEAASKETSEVDQKAETEKADTEDGEKKDK AKEEEPSEPANEEKKVPKNRPGLKKEEPEAFMASFFAGLEVYQTKMLNYLARNFYNLRLL ALFVAFAINFILLFYKVTGDDSGDEDPDPWNGDDEDEDEGGMEYFVLQESTGYMAPTLRF LAILHTIISFLCVVGYYYLKVPLVVFKREKEIARRLEFDGLYITEQPSDDDIKGQWDRLV INTPSFPNNYWDKFVKRKVINKYGDLYGAERIAELLGLDKSALDFNPTEETVVKEASLVS WLSSIDTKYHIWKMGVVFTDNSFLYLVWYTTMSILGHYNNFFFAAHLLDIAMGFKTLRTI LSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFH MYVGVRAGGGIGDEIEDPAGDPYELYRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQ QEQVKEDMETKCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQ ESYVWKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 14676 nt NT seq  +upstreamnt  +downstreamnt atggctgaaggtggagaaggggaggatgaaattcagttcttaagaactgatgatgaagtg gtgctgcagtgtgtcgcgagcatccagaaagaaaatcgcaagttctgcctgactgcggaa ggactcggaaatcgactgtgttacctggaacccacatcagaagcaaagtatgttcctcca gacttgtgcatctgtaactttgtgctggagcagtccctttctgtgcgggccctgcaggag atgctggccaaaactgggccaaacagcgaaggaaggctcataagaaaggcggcacaaggg ggtggacaccggaccctactctatggccacgccatcctcctcaggcattccttcagcgga atgtacctaacctgcttgaagacgtcaaggtccttgacagataaactgtcttttgatgtg ggattacaagaggattcgacaggtgaggcctgttggtggactatccaccctgcctcaaag cagaggtcagaaggagagaaagtgcgcattggtgatgacctcatcctagtcagcgtgtcc acagaacgctatctgcatctgtccatctccaacggcaacatccaagtggatgcctctttc atgcagactctgtggaatgtccaccctacctgctcaggcagcagtgtggaagaagggtac ttgcttggtggtcacgtgatgcgtctgtttcatgggcatgacgagacccttaccattcca gggtcagaccagagtgaagaggaacagaggatagtgaactatgaggcaggtaaagcaggt gctaaagccaggtctttgtggagactggaaccgctcagaatcagctggagcgggagccac attcgctgggggcagcctttccgccttcgccacctcaccacgggtcactacctggcactg acggaggacagggggctggtgctgcaagaccgggagaaatctgacacgaaatccactgcc ttctgcttcagagcctccaaggacaagcaggattccagcccgaagcgagatgttgaaggc atgggggtggcagagattaagtacggagactcgatctgcttcgtcctacatgtggcctcg gggttatggttgtcctaccaggcgcctgatgtaaaatcttctcgcctgggacctctcaaa agaagggcctgtcttcacgtggagggccacatggacgacgggctgacccttcagcgctgt cagcacgaggagtcccgggctgcccgcatcatccgcaacaccacgcggctcttcagccac ttcatcagagacttggacagcctgagagggaagaatcgcgtggcagtggccctgcatatt gaggaggtcctgcagaccctgaatgacctcatcacctacttccagcttccagatgccgag ctggagcacgaggagaaacaaatcaagttgcgttcactcaagaaccggcaaaacctcttc aaacaggaaggaatgctgactctggtgtccaactgcatcgaccggctgaacctgtacaac agcgcggcgcacttcggggagagcgccggggaggaggcggccggggcctggaaggacatt ctcaacctgctatacgagctgctggccgccctgatccgcgggaacagaaacaactgcacc cagttctcccaaaacctggactggctggtcagcaagctggagagactggagtcctcatca ggaattcttgaggttcttcactgcatcttaattgaaagcccggaggcgctcaacatcatt cagagaggacacattaagtccatcatctccctgctgtacaaacacggacggaaccacaag attttggacgttctctgttccctctgtgtttgcaatggagtggctgtaagagccaatcag aacctcatttgtgataacctgctcccaaagagggacctgctcctccagacgcgattggtt aatgatgtccaaagcatgaggcccaatattttccttggcatgagtgagggctcagcacag tacaggaagtggtactatgagctgatgattgaccaggtggaccatttcctgaccagtgag ccgtctcacctgcgtgtgggctgggcaaactccaaagggtacgccccctatcctggaggg ggcgagggttggggtggaaacggcgtgggggacgacctgtactcctatagctttgatggt cttcacctctggtcaggtcggattccccgggcagtggcctccatcagccagcacctgctg acctcggacgacgtggtgagctgctgcctggacctgggggcccccagcatctccttccgg atcaatgggcagcctgtgcagggcatgtttgagaacttcaacaccgacgggctcttcttc cctgttgtcagcttttctgccggggtcaaagtgcgattcctgttgggcggtcgccatggc gacttcaaattcttgccaccctctggttatgcgccgtgctacgaagctctgctgcccaag gagaaaatgcgagtggagccggtgaaggagtacaagcgagactttgatggcgtgagggat ctgctgggcaccgcacagttcatgtcgcaggcttccttcatacctatgcctgtggacacc agccagattgtgctgcctccgcaccttgagaaagtacgggacaaactggctgaaaacatc catgaactgtggggtatgaacaagattgaacttggctggtcttatggtaagatgcgagat gacaacaagaggcatcatccctgccttgtggatttctccaaactccctgaaactgaaaag aactataacctgcagatgtcaactgaaactttaaagaccttgttggcgttaggatgccac gttgtccacatccatatcgatgcagaagaagacttgaaaaagatgaaacttcccaagaac tacatgatgtctaatggttataagcctgcgccactggagctttctgatgtgaaactgacc cctggtcaggaagttctggtcgataaactggccgagaatgcccacaatgtctgggccaag gacaggataaaacaaggatggacctatggcattcagcaggatttgaagagcaagcgcaat cctcgcctggtgccatatgctttactagatgagcgcacaaagaagtcgaaccgagatagc ctccgcgaggctatccgaacactgattggatacggatacaacattgatcctcccgaccaa gagagtgcggcgcatacctctgagaggctgagcatcgataagatacggttcttccgcgtg gagcagacgtacgctgtgaagaccgggaggtggtacttcgagtttgaggcggtgacgggc ggagacatgcgtgtgggctgggcgcgacctggctgcaggcctgacattgagctgggcatg gacgaccaggcctacgtgtttgatgggttcaggggtcagcggctgcacatgggaggcaga ttcttcggtcgcagctggcacgcaggagacgtggtgggctgcatgatcaacatggaggac aagtccatgatcttcaccctcaacggcgagattctcatcaccaacaaaggctccgagctc tgcttcgctgactttgagactgaagacggcttcatcccagtgtgcagcctgggcctttct cagaccggccgcatgaaccttgggaaggatgctagcaccttcaagtactacaccatgtgc gggctccaggaaggctttgagccttttgccgtcaacatgaatcgagatgtcaccatgtgg ttcagcaagcgcctaccaacctttgtcaatgtgccaaaggaccataaccacattcaggta accagaattgacgggactattgacagcccaccctgtctcaaagtgacccacaagaccttc gggacccagaacagcaacgctgacatggtgttctgtcgtctgagcatgcctgtggaattc caaacggccttcaggagcaacccgtcaattgacatgaacggagtgcacgaagacgactcc caaaaacccaaacacaggtatcccgtgaagtccctgaaacactctgaggatggaagaagg gcggattacagcagcatcacaatgtactaccactctgttagggtgtttgcagggcaggac ccttcctgcgtgtgggttgggtgggtcaccccggactaccattactatagcaaccacttc aacctcagcaagaatcgaactgtcactgtaaccctgggagatgagcgtgggcgagtccat gagagtctgaggaggagcaactgctatatggtgtggggcggagacatcgcgagcgcctcc cacacttccggtcgtagcaatgtagaccttgagattggctgcctcatcgacctaatgaca ggccttgtcaacttctctgccaatggcaaggagctaccaacctcttaccaggtggaacca aattcaaagctcttcccagcagtttttgtgctgccaactagtcccaacctgttccagttt gagttggcaaagataaagaacgccatgcccctctcctcggctatcttcaagagcgagcac aagaaccctgtgccacagtgcccgcctcggctggatgtgcagactattacctcggtgctg tggagccgcatgcccaacaccttcctgaaggtggagacggcccgggtcagcgagaggcac ggctgggtggtgcagtgcctggagccactgcaaatgatggctgtgcacatccctgaggag aacaggtgtgtggacataatggagctctcagaactagatgacctgaggaaattccactac cacacactgaagctgtactgcgccctctgtgctttgggaaacacccgggtggctcacgcc ttgtgcagccacctggaccagtcccagctgctctacaccatcgacaaccagtacctggcg ggcatgctgcgcgagggcttctacaacgtgctcatcagcatacacctggagacctccaag gaggcccggctcatgatgaacaacgagttcatcatcccggtcaccgacgagacgcggagc atccgcctctttcccgacgagtccaagaggcaccaacccccgggcgtggggctcagcacg tcgcttaagccccgcttcaatttcgccccgccctgcttcatctccatcaagcgagaccag cacctctccagccccgagatccccctggacatcctgaaggagaaggccatcagcatgctg acggaggcagtgcagggtggcggtcaccacatccgcgaccccgtggggggcagcgtggag ttccagttcgtgcccatcctcaagctgatcggcacactccttatcatgggcattctggga agcgaggacgtccagaagatcctgctgctcatcgaccccaatgtctttggcgagcgcaag gaggaggagccagagcaagccaccgagaaggaggacgtgaccagcaatgaggagaaggcc gtggaagcaggagaggaggaggccaaagatggcaagcagccagtgaagggcttgcttgag aagaggctgccagagtcagtcaaaaggcagatgtgtgaactgcttcattacttctgcgac tgcgagctgaaacaccgaatcgaggccatcgtgtccttctccgacagcttcgtgtcgaag ctgcagtacaaccagaagttccgatacaacgagctaatgcaggccctcaacatgtccgcc gccatcacagcaaggaagaccaaggaatttcgatccccaccgcaagagcagattaacatg cttctgaacttcagtatgggagaggactgtccctgcccagaggacatccaagaggagctg tatgagttccacaatgaacttcgcctgcactgtggaatcccgattgaagaggaggaagag gagcaggacacctccataaaaggccgcctccttgcccttgtgtacaagatcaaaggtccc ccccagaaaacagaggagaatcctacagaagaagaacaggctgcacctaccaacctgaag gagctgatctcccagacgatggtgagctgggcgcaggagtgccacatccaggacccggag ctggtgcgcgtgatgttcagcctgctgcggcggcagtacgactgtgtgggcgagctgctc cgtgccatgaggaagagctacaccatcagcgccgcctccgtgaaggacaccatcaacctg ctggcctccctgggccagatccgctccctgctcagcgtgcgcatggggaaggaggaggag aggctcatgattgacggcctgggtgacatcatgaacaacaaggtgttctaccagcacccc aacctgatgcgggtcttgggcatgcacgagactgtgatggaggtgatggtcaacgtgctg ggaggagacaagtcacaggagatcgcctttcccaagatggtggccagctgctgtcgattc ctgtgctatttctgccgcatcagtcggcagaaccagaaggccatgttcgaccacctgagc tatctcctggagaacagcagtgtgggcctagcatctccagccatgaggggctccactccc ctggatgtggccgcatcctcagtgatggacaacaacgggctggccctggcactggaagag cctgacttggagaaggtggtgatgtatctggcgggctgtgggctccagagctgcccaatg ctcctggcaaagggataccccgacatcggctggaaccccatcgaaggggagcgctacctg tccttcctccggtttgcagtcttcgtcaatggtgaaagcgttgaggaaaactctagcgtg gtggtgaagctgttgattcggcgtcctgagtgttttggcccagcgctccggggagagggg ggcaatggcctgttggccgctatgaaagaggccatcaagatctcagagaacccctccatg gacttgcccagctccgcccacggggtcagctcagtcatgcccgccgacggcgatgaagag gaggaggtggtgcacatgggaaacgccatcatgtccttttactccgccctcattgacctg ctggggcgctgcgctccggagatgcaccttatcaacaagggaaaaggagaggccctgaga atccgtgccattctgcgctccctggtgcccacggaggacctggtgggcatcatcagtata cccctcaaaatgcccatagtgaataaagacggcaccgtgacggagcctgacatgtcggcc agcttctgtccggaccacaaggcccccatggtgctgttcctggaccgtgtgtatggtatc gaggaccaaagcttcctgctgcacctgctggaggtgggattcctgcctgacctgcgggcc tctgcctccttggacacggaggcgctgagcaccacggagacggccctggccatgaacagg tacattggctcagcgatgctgccgctgctgacccgctgcgcctcgcacttcggcggcact gagcactacgccgccctcatcgactccacgctgcacaccatctaccggctgtccaagggc cgctcgctcaccaaggcccagcgtgacgccatcgaggagtgcctgctcgccatctgcaag tacctgcgtccctccatgctgcagcagctcctgcgccgcctcgtcttcgacgtgccgttg ctgactgagtactgcaagatgcctctgaagctgctgaccaatcactacgagcagagctgg aagtactactgccttccctctgggggcggcggcttcggcatggcgtctgaggaggagctg ctcctcaccaagaaactcttctggggcatcttcgactcgctctcacagaagaaatacgag caggagctctttaaaatggccatgccctgtctgagtgccatcgccggggccctgccgccg gactatgtggactcctccctcagcaccaccctggagaagcagacctcggtggacgcccat ggcaacttcgaccccaggcccatcagcacagccaacatttccctccctgaaaaactggaa tatgttgccaacaagtacgctgagcattcccatgaaaaatggtctgcagagaaggtaaca ttaggctggaagtatggggagagcattgatgagaaagtcaagacacatcccatgatgagg ccttacaaatcgctcaccgacaaggagaaggaggtttaccgctggcctgtgaaggagtct ctgaagaccatgctagctatgggctggaacattgagaggaccaaggaaggggaggccatg tttcagcaacgggagagtgagaaactgcgcaagatctcccagtcttctcagggaaatggc ttcaacccatgtccactggacatgagcaatgtggttctttccagagagttacagggcatg gtggagattgtggcagaaaattaccataatatttgggcaaagaagaagaaaactgagctg ggaagcagaggaggcgggacacaccccctgctggtgccttacgatacgctgactgccaag gagaaggctagggacagagagaaggcccaggacctcttccgtttcctgcaggtcaacggc tacgccatcaccagggggctgaaggatatggagcaggactcgtcctccatggagaagcgc tttgcgtacaaatttctgaagaagcttctgaagtacgtggactcggcgcaggaatttatc gcccacctggaggccatggccaccagcgggaagaaggataaatccccacatgaacaagag atcaagttctttgccaaggtgctcctccccctgattgaccagtacttcaagaaccactcc ctctacttcctgtcctctcccagctctaatctgggtggcagtggttacgcatccaataag gagaaggagatgctcaccagcctcttctgtaaactggcagctcttgtcagacacaggatt tccctctttgggagtgactctgccaccatggtgagctgcctgcacatcctggctcacacg ctcgacaccaggacagttatgaagtcaggctcagagctggtgaaggcagggctgcgcact ttctttgagaatgcggctgaggacctggagaagactctagaaaacctgaagctggggaag ttcacgcactcccgcagccagatgaagggcgtgtcccagaacattaactacaccacagtg gccctgctgcccatcctgaccgcgctgttcgagcacatcacccagtaccacttcggagtg gacctgctgttggatgatgtccagttgtcctgttatcgtatcctgaccagtctttattca ctaggaacaggaaagaacatctacgtggagaggcagctgccggccctgggtgaatgtctg gccaccctagcaggagccatgcctgtggccttcctggagccccacctcaacgtgcacaac ccctggtctgtcttcaacaccaagaccccccgagagcgggctatcctcagcatgccagac tcggtggaggagatgtgcccggagatgccccgcctggatggcctgatgaaggacatcaac gacatgtcggagtctggggcgcgctacactgagatgccccacgtcatcgaggtggttctg cccatgctctgcaactacctgtcctactggtgggagaaggggccggagaacacatctaac ggtagcagcagcagctgctgcaccacagtcacctccgagcacctcagtgtcatcctgggg aacatcctcaagatcctcaacagcaacctggggattgacgaggcctcctggatgaagagg atcgccgtgtatgcccagcccatcatcagcaaggcacgggcggacctgctgaggacccac ttcctgcccacactggagaagctgaagaagaagacagtgaaagtggtggcagaggaggag ctcctgaaggccgacagcaagggcgacacacaggaggcggagttgctgattctggatgaa tttgctgtgctctgccgggacctctatgccttctaccctatgctcatccgctatgtggac atcaacaggtctaggtggttgaaggagccagatgctgactccaatgcactttttaagatg gtggcagagatcttcatcctctggtgcaagtcccataacttcaaacgggaggagcaaaac tttgtggttcagaatgaaatcaacaacctgtccttccttactggagatagcaagaccaag atgtccaagtcatttctgggaaagacagggggtcaggaccaggagaggaggcacaagaaa aggaggggggaattctactccatccagacctccctcatagttgcggccctgaagaagctg ctgcccatcggcctcaacatgtgtaccccgggagaccaggagctcatatctttggccaag atccgctacagtctgaaagatacggatgaggaagtcaaggaccacctgagacaaaatctg cacctgcaagagaagtcagaggatcctgcagtgaggtggcagctgaacctgtacagggac gtggtggtgaagagtgatggtcctccagaccccgagcgcaccgtggcccgagtacagagc atctccgctgccgtcttccacctggagcaggtggagcagccactgaggtctaagaagtgt gtgtggcagaagctgctctccaaacaacgcaagcgcgcagtggtggcgtgctttcgcatg gctccactctacaacttacccaggcacaaaaataacaattacttcctgaacgcctaccaa cactattggctggaaaaaatgcatgagaacacagactatgacagtctgctctccatgcta acgaaggtccacaagaaggtggaggaggaggaagaggaggaggcagaagtgcaacctgac ccgcttcatcagctcatcctgcatttcagtcacaatgctctcaccgaacggagtgccctg gatgaagatcctttgtacattgcttatgctgatatgatggctaagagttgtgcagaaaat gaagaggaggaagaagaagaagggaaagaaaagacctttgaggagaaggagatggagaaa cagaagactctgtaccagcaggccagactgcatgaccgcggggcggctgagatggtgctg cagatgatcagtgccagcaaaggtcggctgggacccatggtgaccttcactctcaaactg ggaatctccgtcctcaatgggggcaatgtggttgtccagcagaaaatgctggattacctg aaggaaaagagagatgttggttttttcaagagtttatctggactcatgcagtcttgcagt gtcctggacttgaatgcatttgaaaggcaaaataaagcagaaggtcttggaatggtcact gaggaaggatcagtcaacgtgagtgagcggggttccaaggtactgcaaaatgatgagttc accaaggatctctttaggttcttgcaacttctttgtgaaggtcacaacaacgacttccaa aacttccttcgtactcagacaggaaacaccaccacagtcaatatcatcatcagcacggtg gactaccttctccgtctgcaggagtccatcagcgatttctactggtattactcgggaaaa gatgtcatggacgagcctgggcagcgtaacttctccaaagccctggctgtagccaagcag atcttcaactctctgactgagtacattcagggcccctgtattggaaatcagcagagtctg gcccacagtaggctgtgggatgctgtggtggggttcttacatgtctttgccaacatgcaa atgaagctctcacaggattcaagccagattgagttgttgaaggagctgctggacctgcaa aaggacatggtagtcatgatgctttcccttctggaaggtaatgtggtgaatgggacaatt ggcaagcagatggtggacaccttggtggaatcctctagcaatgtggagatgatcctgaag ttctttgacatgttccttaagctgaaggatctgactacttctgacagtttcaaggaattt gaccctgacagcaagggcgtaatctctaagaaggaattccagaagtccatggagaaccag aagcagtacacccagtctgagattgagttcctgctctcctgtgtagaggccgatgagaac gatatgttcaactatgaagagtttgtggagcgcttccatgagcctgccaaggacattggc ttcaatgtggcggtgctgctaaccaatctgtcagagcacatgccccacgactcacggctg gctgccttcctagacctggccgagagtgtgctcaactattttgagccctaccttggccgc attgagatcatgggcggcgccaagcgcattgagagggtgtactttgagatcagtgagtcc agcagaactcagtgggagaagccacaggtcaaggagtccaaacggcaattcatcttcgac gtagtcaacgagggcggagagagcgagaagatggagctcttcgtcaacttctgtgaggat accatttttgagatgcagcttgcttcccagatatctgagccggatgctgtggagcgacca gaggaggacgaggatgacgcccacagcatcctggaagaactggaagaggaagaagaggag catgccttggagtcatcctctgccttcactattgcctgtgtttccatgaagaagaacttg tcccacttccgtcagcagatctcagtcaggaacatgcgcaagcaattcaagaagttcagg aagatgagcatccgggagatgattaagggtttcttctccttcttctggatgatcttcact ggtctcttccgcttcatgtacaacctggtctggggcttcttccatatcctctggacttcc atgtttggtgggggcctggtggagggcgccaagaatatgaaggtgacagacattctgggc aacatgcctgacccaacgcagtttggaatccatggtgacgtgctggaatcagagaagttg gagacgagcgaatcagcatcaggggccgagatggtacagatggcaaaaggggaccagtct gaggtggatttgatgacggagctgatgaacataccacctaagagagaaggggggaagcac ggacctgaacctggcctgggagatgtctctgagatcgtcggagttgacgcaccttcatta gctagtgccgtaaagcagaaaaaagctcagaaagaggctgcatctaaagagacatcggag gttgatcagaaggcagagacggagaaggcagacacagaggatggcgagaagaaggacaag gccaaggaggaggagccttcagagcccgcaaatgaggagaagaaagtccccaaaaacaga cctggcctgaaaaaggaggaaccagaggccttcatggccagcttttttgcaggattagaa gtctaccagactaagatgctgaactatctggcgagaaacttttacaaccttcgcttgctg gctttgtttgtcgcctttgccatcaactttatccttctcttctacaaggtgactggagat gactcaggtgacgaagaccctgacccctggaatggcgatgatgaagatgaggatgagggt ggtatggagtactttgtgttgcaggagagcactggctacatggctccaactctacgcttc ctggctatactccacaccatcatctctttcctttgtgtggtgggatactactatctaaag gttcccctggtggtgtttaagcgagagaaggagattgccaggaggctggagtttgatggc ctgtacattacggagcagccctcggatgatgacatcaaaggacaatgggatcggctggtc atcaataccccatccttccccaataactactgggacaaatttgtgaagcgaaaggtcatt aataagtatggggatctctacggggccgaacgtattgcggagctattgggtctggacaag agtgccttggacttcaaccccacagaggagacagtggtgaaggaggcctcattggtgtcc tggctgagctccattgacacaaagtatcacatctggaagatgggcgtagtgttcactgat aattctttcctctacctggtgtggtacaccaccatgtccatcctggggcattacaataac ttcttctttgctgcccacttgctggatattgccatgggcttcaagacactgagaaccatt ctgtcctctgtcacccacaacggtaaacagcttgtgttgactgtgggactgctagctgtg gtagtgtacctctacacagttgtggccttcaatttcttccgcaagttctacaacaagagc gaggacgaggacgagcctgacatgaagtgtgatgacatgatgacctgctatctgttccac atgtatgtgggcgtgcgtgctggcggtggtatcggtgacgagattgaggacccagcaggc gacccctacgaactctaccgcattctgttcgacatcactttcttcttctttgtcattgtc attctgctggccatcatccagggtctgatcattgatgcatttggagagctgagagatcag caggaacaagtgaaagaggacatggagactaaatgcttcatctgtgggattggtaatgac tactttgatacgaccccacatggctttgagacacataccttacaagagcacaacctggcc aactacctgttcttccttatgtacctcatcaacaaggacgagacggagcacactggtcag gagtcgtacgtttggaagatgtaccaggagagatgctgggacttcttccctgccggggac tgtttccgcaagcagtatgaggaccagctggggtag

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