Actinobacillus succinogenes: Asuc_0942
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Entry
Asuc_0942 CDS
T00558
Name
(GenBank) 2-oxo-acid dehydrogenase E1 subunit, homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
asu
Actinobacillus succinogenes
Pathway
asu00010
Glycolysis / Gluconeogenesis
asu00020
Citrate cycle (TCA cycle)
asu00620
Pyruvate metabolism
asu00785
Lipoic acid metabolism
asu01100
Metabolic pathways
asu01110
Biosynthesis of secondary metabolites
asu01120
Microbial metabolism in diverse environments
asu01200
Carbon metabolism
asu01210
2-Oxocarboxylic acid metabolism
Module
asu_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
asu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
Asuc_0942
00020 Citrate cycle (TCA cycle)
Asuc_0942
00620 Pyruvate metabolism
Asuc_0942
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Asuc_0942
Enzymes [BR:
asu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
Asuc_0942
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
DUF3089
Motif
Other DBs
NCBI-ProteinID:
ABR74310
UniProt:
A6VMW3
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Position
1007622..1010282
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AA seq
886 aa
AA seq
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MSEMLKNDVDPIETQDWLSAIDSIIREEGVERAQYIIEKLMHHAHGQNVSLPVGEAITTD
YVNTIPLSEQPAYPGNLKIERRIRSAVRWNAIMAVLRSQKKDLDLGGHISTYQAAATMYE
VCFNHFFKAATEQDGGDLVFFQGHAAPGMYARAFLEGRITEEQMDNFRQEAFADGLSSYP
HPRLMPEFWQFSTVSMGLGPVNAIYQARFLKYLANRGLKDTSNQKVYAFLGDGEMDEIES
KGALAFAAREKLDNLIFTISCNLQRLDGPVDGNGKIVQELEGLFTGAGWEVIKVMWGSNW
DRLFAKDTSGKLTQLMMEVLDGDYLTFKSKDGAYVREHFFGRYPETAALVADMTDDEIWA
LRRGAHDAEKMYAAYAKAQTAGRPVVILAHQVKGYKIPEAQSKNTAHQSKKMSQQSLKGF
RDYFQLPLTDEQVENLEYVKFPEGSDEYNYLHGQRKALNGYLPARRAKFDTEFKVPALTD
FAQLLDAQARPISTTMAFVRVLNTLLKDKNIGKQIVPIIADEARTFGMEGLFRQIGIYNP
HGQNYVPSDRDLVAYYREAKDGQVLQEGINELGATSSWVAAATSYSVNNLPMIPFFVYYS
MFGFQRVGDMMWLAGDQLARGFFIGGTSGRTTLNGEGLQHEDGHSHIQSSVIPNCVSYDP
AFAFEVAVIMQDGINRMYGEKQEDVFYYITTLNETYDQPAMPAGAEEGIRKGIYKFETVG
KGEAAVQLMGSGAILRHVREAARILADDYGITSDVFSVTSFTEVAREGAEAARWNLLHPT
EQQRVPYIAQVMSDKPAVAATDYMKLYAEQVRAFIPAQNYHVLGTDGFGRSDSRANLREF
FEVDAHYVVIAALSQLAKQGKVDAKVVAEAIAKYDIKADRANPLYA
NT seq
2661 nt
NT seq
+upstream
nt +downstream
nt
atgtcagaaatgttaaagaatgacgtagatccaatcgaaactcaggattggttatcagct
atcgattccattattcgcgaggaaggcgttgaacgcgctcagtatattattgagaaacta
atgcatcacgcacacggtcagaatgtcagtttgcctgtcggcgaagcaattaccacggat
tatgtcaatactattccgctttcagaacaacctgcttatccgggcaatttaaaaattgaa
cgccgcattcgttccgctgtacgttggaatgcgattatggcggttctgcgcagtcagaaa
aaagatcttgatttaggcggccatatttctacttatcaagcggccgcaactatgtatgag
gtttgttttaaccatttctttaaagcggctaccgagcaagacggcggtgatttagtattt
ttccaaggccatgccgcaccgggtatgtatgcacgcgcatttttagaaggccgtattact
gaagagcaaatggataatttccgtcaggaagcgtttgccgacggtttatcttcttatcct
catccgcgtttaatgcccgaattttggcagttttctaccgtttctatgggattgggcccg
gtaaatgccatttatcaggctcgttttctgaaatatcttgccaatcgcggtttgaaagat
acttctaaccaaaaagtctatgctttcttaggcgacggtgaaatggatgaaatcgaatct
aagggagcattagcttttgctgcccgtgaaaaattagacaatttgattttcacaatcagc
tgtaacctgcaacgtttagacggtccggtcgacggtaacggtaaaatcgtacaagaatta
gaaggattatttaccggtgcgggctgggaagtgattaaagtcatgtggggcagcaactgg
gatagattattcgctaaagatacctccggtaaattgactcagttgatgatggaggttctg
gacggcgattacttaacctttaaatctaaagacggtgcttacgttcgcgaacacttcttc
ggtcgctaccctgaaaccgcagcgttagtggcggatatgacagacgatgaaatatgggca
ttacgccgcggtgcgcatgatgcggaaaaaatgtatgcggcatatgctaaagcgcaaact
gccggcagaccggttgtcattttagctcaccaagtgaaaggttataaaattcctgaagcg
caaagtaaaaataccgctcatcaatcgaaaaaaatgtctcaacaaagccttaaaggtttc
cgtgactacttccagttaccattaacggatgagcaggttgaaaacttagaatacgttaaa
ttccctgaaggttctgacgaatataactacctgcacggtcaacgtaaagcgttaaacggt
tatttgccggcacgtcgagcaaaattcgatactgagtttaaagtgcctgcattaacggac
ttcgcccagttgttagacgcacaagcgcgcccgatttcaacgactatggcctttgttcgc
gtattgaatactttactgaaagataaaaatatcggtaaacaaatcgtaccgattattgcg
gatgaagcgcgtactttcggtatggaaggtttattccgtcaaatcggtatttataatccg
cacggacaaaattacgtaccttcggaccgggatttagtggcttattaccgagaagcgaaa
gacggtcaggtattgcaggaaggaattaacgaattaggtgcgacttcatcttgggttgcc
gccgcaacatcttattccgtaaataatttgccgatgattccgttcttcgtttattactcc
atgttcggtttccaacgtgtaggcgatatgatgtggttagccggcgaccaattagcccgc
ggcttctttatcggcggtacttccggccgtacgacattgaacggcgaaggtttgcagcat
gaagatggtcacagccacattcagtcgtcggtgatcccgaactgcgtatcttatgatccg
gcattcgcgtttgaggttgcggtgattatgcaagacggtattaaccgtatgtacggtgaa
aaacaagaagacgtgttctactacatcaccacattaaatgaaacttatgatcaaccggca
atgccggccggtgccgaagagggtatccgtaaaggtatctacaaatttgaaaccgtcggt
aaaggcgaagcggcagttcaattaatgggttccggcgcaatcttacgccatgttcgtgaa
gcggctcgaattttggctgatgactacggtattacttccgatgtattcagcgtgacgtca
tttaccgaagtcgcccgtgaaggtgcggaagcggctcgttggaatttattacatccgacc
gaacaacaacgcgtaccttacattgcgcaagtgatgtccgataagccggccgttgccgca
accgactacatgaaactttatgcggaacaggttcgtgcgtttattccggcacaaaattat
cacgtattaggtaccgatggttttggtcgctcggacagccgtgcaaacttacgtgagttt
ttcgaggtggatgcacattatgtggtgattgccgcactatcgcaattagcgaaacaaggc
aaagtcgatgcgaaagtggtggcggaagccatcgctaagtacgacattaaagcagatcgt
gcaaatccgttatacgcataa
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