Brevibacillus agri: BA6348_09650
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Entry
BA6348_09650 CDS
T05855
Symbol
cobA
Name
(GenBank) uroporphyrinogen-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
bagr
Brevibacillus agri
Pathway
bagr00860
Porphyrin metabolism
bagr01100
Metabolic pathways
bagr01110
Biosynthesis of secondary metabolites
bagr01120
Microbial metabolism in diverse environments
bagr01240
Biosynthesis of cofactors
Module
bagr_M00924
Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
bagr_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
bagr00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
BA6348_09650 (cobA)
Enzymes [BR:
bagr01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
BA6348_09650 (cobA)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
BA6348_09650 (cobA)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
TP_methylase
HEM4
Motif
Other DBs
NCBI-ProteinID:
QAV13000
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Position
1939940..1941454
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AA seq
504 aa
AA seq
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MNAGRVLFVGAGPGDPKLLTIRGMEALQKADVVVYDRLASPLLLSHVKRDARLVYCGKER
DRHTLPQEEINLLLIREAKRGKTVVRLKGGDPSMFGRVGEEAQMCVQHGVPYEIVPGITS
GMAAPLYAGIPLTHRDYNSSVAFVTGHLCDKNAGKEPDWAALARMETLVIYMGVKNLPHI
QAQLLACGKSGDTPVALVRWGTVGEQQTLVGSLATIDRDVAKAGFSAPAIIVVGEVVRLR
EQLNWYESRPLFGQRVALAAIPGAGGSDALAGRLEQLGAEVIAIPLVKRPLLAVDAAEFP
EDLTAYGWIVLDDAQQAEAFLAELGRRRFDLRRLTSKLAVRGKQAALFLESRGLYPERVF
DHAATPAAMSRELARNGGERILHVRAKCGSTPAQSAAEFLHLPAGGVLEWEETHPVVPWM
KKLAFDWFAAADGEVLPALADFAGAGWESVPLFCADAKTQEVARQMGWRVVIDEDVESLA
RGIHSREQVASAACKLYGTPSFLT
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgaacgctggcagagtcttatttgtaggggctggccctggcgatccgaaactgctcacc
attcgcgggatggaggcgctgcaaaaagccgacgtcgtcgtgtacgaccgactggctagc
ccgctgcttctctcccacgtcaaaagggacgcccggcttgtttactgcggcaaggaaagg
gaccgccacacactgccacaggaagagatcaacctcctgttgattcgggaagccaagcga
ggaaaaaccgtggttcgcttaaaaggcggggacccgagcatgttcgggcgggtaggcgag
gaagcgcaaatgtgcgtacagcatggcgtgccgtacgagatcgtgccggggatcacctcc
ggcatggcggccccgctgtatgcagggattcctttaacccaccgcgactacaattcctcc
gttgcctttgtcaccgggcatctgtgcgacaaaaatgccggcaaggagccggactgggca
gcactggcgcggatggagacgctcgtcatttacatgggcgtgaaaaacttgccgcacatc
caggcgcagcttttggcctgcggaaaaagcggggatacccctgtcgcgctcgtcagatgg
ggcacggtaggagagcagcagacattggtcgggtcgcttgcgacgattgaccgcgatgtc
gccaaagcgggcttttccgcgccggccatcatcgtcgtgggcgaggtcgtccggctgcgc
gagcaactgaactggtacgaatcgcggccgctgttcggacaacgggtggcgcttgcggcc
attcccggagcaggcggcagcgacgcactggcgggcaggctggagcagctcggtgcagaa
gtcatcgcgattccgctcgtgaagcgccctttgctcgctgtggatgctgctgaatttccc
gaggacctcacggcatatggctggatcgtgctcgacgatgcgcagcaggcggaggctttt
ttggcagagctgggcagacggcggtttgacctgcggcggctgacgagcaagctcgctgtg
cgcgggaagcaggcggctttgtttctggagagcagaggactgtacccggagcgcgttttc
gatcacgcggccactcctgcggctatgagcagggagcttgcgcgaaacggcggggagcgg
attttgcatgtgcgcgccaaatgcgggagtactcctgcccagtcagcagcagagttcctc
catctgccagcgggaggcgtcctggagtgggaggagacacacccggtcgttccttggatg
aaaaagctggcgtttgactggtttgctgccgctgacggggaagttttgcctgccctggcg
gattttgcaggagcgggttgggagagtgtgccgcttttttgcgccgatgcgaagacgcag
gaggtggcgagacaaatggggtggcgcgtcgtcatcgacgaagacgtggagagcttggcc
cgaggaatccattcgcgagagcaggtcgccagcgcagcatgcaagctgtacggcacccct
tcttttcttacgtaa
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