KEGG   Bison bison bison (American bison): 104985738
Entry
104985738         CDS       T08726                                 
Symbol
WNK2
Name
(RefSeq) serine/threonine-protein kinase WNK2
  KO
K08867  WNK lysine deficient protein kinase [EC:2.7.11.1]
Organism
bbis  Bison bison bison (American bison)
Pathway
bbis04928  Parathyroid hormone synthesis, secretion and action
Brite
KEGG Orthology (KO) [BR:bbis00001]
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    104985738 (WNK2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bbis01001]
    104985738 (WNK2)
   01009 Protein phosphatases and associated proteins [BR:bbis01009]
    104985738 (WNK2)
Enzymes [BR:bbis01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     104985738 (WNK2)
Protein kinases [BR:bbis01001]
 Serine/threonine kinases: Other
  Wnk family
   104985738 (WNK2)
Protein phosphatases and associated proteins [BR:bbis01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     104985738 (WNK2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr CCTL2_WNK OSR1_C Pkinase_fungal
Other DBs
NCBI-GeneID: 104985738
NCBI-ProteinID: XP_010834363
UniProt: A0A6P3GSA5
LinkDB
Position
Unknown
AA seq 1959 aa
MVGVNVLLQLRSLPQLLLRLKAGLKDAGAPEARPELGRARREEPEEEEDDEDDLKAVATS
LDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGL
QHPNIVRFYDFWESSARGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGL
LFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMY
EEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKVHDPEIKEI
IGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSAIALRLWVEDPKKLKGK
PKDSGAIEFTFDLERETPEDVAQEMIESGFFHESDVKIVAKSIRDRVALIQWRRKRIWPA
LQPQEQRDLGSPDKARGPPTPLQVQVTYHSQAGLPESEEPEADQHLLTPALPASATSLAS
DSTFDSGQGSTVYSDSQSSQQSVVLGSLADGAPPASQCVCSPPVSVSDGPVLPHSLPSLG
AYQQPATVSQPNPSGQCSGPHGLESVMVHSVCAGLLSVRNHAKPSLLAQPVPLPQVLAPQ
PVGPLQPAPSHLPPYLAPASQVVAPAQLKPLQMPPAPLQPLAQIPPQMPPLPVVPPIAPL
ATVDNLPTALPDLPATSGPTVPPPSQYFPPAVILPSLPLSATPAPLPASPALPLQTVKLP
HPAGAPLAVPCQTIVPNVAATATAIPLLAVAPQGVAALSIHPTVAQLPAQPVYPAAFPQM
VPSDVPPSPLHAAQTVQAAAPQPTPPVLPQPHQPSVARLPEQAAPAASAGSQILLGHPPT
YAVDVTTQVATVPAPAAILSPPLPEVLLPPVPELLPQLPGSLAPTVIAAPQSVPVQTAAL
LPPATLPLPSGPGIPGPCPTVQLTVEPAPEEQASQDKQPSLPQSCESYGGSDVPSGREMS
DSCEGAFGGGKLEGKAARKHHRRSTRVRSRQERASRPRLTILNVCNTGDKMVECQLETHN
HKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDMLSEDTDVDRA
SDPGVSPPHLSTCGLGAGEENRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAVEAPESS
PPLPLSSLQPDTSQDSAPSKDQLSSKEKPSFSTDLQLLSQAGPRDLPGGAPAPLVPSSPP
VTALSQDMAPPAASPKLEPATGPAMQAGGSGTPQGPASEHKTPWPLMETLDAQLAAQSPG
MGRGPCAPPLEAPLHPMGLGDPALAREPITKGEPLVGFVDSTIKSLDEKLRTLLYQEHVP
TSSASAGTPVEAGDRDFTLEPPRGDEPRTEASGGSLGLLPPPALEKSEMAPGLEVTLEQS
VSLSVTAESSLSHTLGREGAQVASDSRTAPSAPQDVPASAIPAHLEPTDRTSRVPGETLA
ESMQSCLGMLIEGGQDSQPQPHSTLVSGSPLKWPGQQDGSSPAKTVGRFSVVSTQDEWTL
ASPNSLRYSAPPDVYLDEAPCSPDMKLAVRRAQTASSIEVGMEEPLSSDSGDESPRRRPS
VQKHASLPSSSGGVASDFVKKAAAFLQRSSRAGSPCLETPSRMGVKVPTISVTSFHSQSS
YISSDNDSEIEDADIRKELQSLREKHLKEISELQSQQKQEIEALYRRLGKPLPPNLGLFH
TAPPIGRRRKTSKSKLKAGKLLSPLVQQLKVVASSTGHLSDCSRAPPAKDPAQAGAGPTA
ASDPCGKAVQTQQPCSVRASLSADICSGLASDGGGAHGPGWTVYHPTSERVTYKSSSKPR
ARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLVPGPEPGPQPALHIQAQVNNSNNKKG
TFTDDLHKLVDEWTSKTVGATPLKPSLNQLKQTQKLHDMEATAGWPLASGEARAMNTSRT
AMGMPCLAPVPSPVPTVVIPGAASALPVPMPDSESEKPD
NT seq 5880 nt   +upstreamnt  +downstreamnt
atggttggggtgaatgtgctgcttcagctgcggagtttaccacaactcctgctgaggttg
aaggctggtctgaaggacgcgggggctcccgaggccaggccggagctcgggcgcgcacgt
cgggaggagcccgaggaggaggaagacgacgaggacgacctgaaggctgtggccacttcc
ctggatggccggttcctcaagtttgacattgagcttggccgcggctctttcaagacggtc
tataaagggctggatacggagacctgggtggaggtagcctggtgcgagctgcaggaccgg
aagctcaccaaactggagaggcagcggttcaaggaggaggctgagatgctgaagggcctg
cagcaccccaacattgtgcgcttctatgacttctgggagtccagtgccagggggaagcga
tgcatcgtgctggtgaccgaactgatgacctcggggacactgaagacgtatctgaagcgg
ttcaaggtgatgaagcccaaggttctacgtagctggtgccggcagatcctgaagggcctg
ctgttcctgcacaccaggacgccccccatcatccaccgggacctcaagtgtgacaacatc
tttatcactgggcccacagggtctgtgaagattggcgacttgggcctggccaccctcaag
agagcatcctttgctaaaagcgtgataggtacccccgagttcatggcaccagagatgtac
gaggagcactacgatgagtccgtggacgtgtacgcctttgggatgtgcatgttggagatg
gccacctcggagtacccctactcagagtgccagaatgccgcccagatctacaggaaggtc
acctgtggcatcaagccagccagctttgagaaagtgcacgatcctgaaatcaaggagatt
attggggagtgtatctgcaaaaacaaggaggaaaggtatgagatcaaggacctgctcagc
cacgccttcttcgcggaggacacaggtgtgagggtggagctggccgaggaggaccatggc
aggaagtctgccattgccctgcggctctgggttgaggaccctaagaaactgaagggcaag
cccaaggacagcggggccatagagttcaccttcgacctggagagggagacgccagaagac
gtggcacaggaaatgattgagtcaggatttttccatgagagtgacgtgaagattgtggcc
aagtctatccgtgaccgtgtggcattgatccagtggcggcgaaagaggatctggccagcg
ctgcagccccaggagcagcgggacctcggcagccctgataaggccaggggcccacccacg
cccctgcaggtccaggtgacctaccactcgcaggccgggctgccagagtccgaggagccc
gaggccgaccagcacctcctcacccctgcgctgccggccagcgccacctccctggcctcg
gacagcacgttcgacagtggccagggctcaacggtgtattcagactcgcagagtagccag
cagagtgttgtgctggggtcgctggcagacggagcaccacccgcctcccagtgtgtgtgc
agcccccctgtgagcgtgagtgatgggcccgtcctgccacatagcctgccctccctaggg
gcctaccagcagcctgccacggtgagtcagcccaacccttctggccaatgttctggtcca
catggcctagagtctgtgatggttcattcagtctgtgctggcctgttgtcagttcggaac
catgcaaaaccttctctcctggcccagccggtacccttgccacaggtcctggccccacaa
cccgtgggccctctgcagccagcgccctcccacctgcctccgtacctggctccagcctcc
caggtggtggcccctgctcagctgaagcccctccagatgcctccggcgcccctgcagcca
ctagctcagatccccccgcagatgcctccacttcctgttgtcccccccatcgctccactg
gccacagttgacaacctccccacagcccttcctgacctgccagccaccagtgggcccacc
gtgcctcccccctctcagtatttccctccagctgtcatcttgccaagcctcccactcagt
gccacccccgctcccctgcctgcgtcgccggctctgcctctgcagacagtcaagctgcct
caccctgctggggcaccgctggccgtcccgtgccagaccatcgtgccaaatgtggcggcc
actgccaccgccatccctctgctggctgtggccccacagggcgtggccgccctgtctatt
caccccactgtggcccagctcccggcgcagcccgtgtacccagcggcctttccgcagatg
gtgcccagcgacgtcccgccttctcccctccacgcagcgcagactgtgcaggctgccgct
ccccagccgacaccccccgtgctgccacagccccaccagccaagtgttgcccgcctcccg
gagcaggctgctccggctgccagtgctggaagccagatcctgcttggccacccgcctaca
tatgctgtggatgtcaccacccaggtcgccacagtgcctgcgcctgccgccattctctcc
ccgcctctgccggaagtgctgctgcctcctgtccctgagctcctgcctcagctccccggc
tctctggcccccacagtgatagcagctcctcagagcgtgcctgtccagaccgctgcgctc
ctgccacctgctaccctgccactgcccagtgggcctgggatccctggtccctgcccgacc
gttcagctgacggtggagccagcccccgaggagcaggcctcacaggacaagcagcccagc
ctccctcagagctgtgagagctatggaggctctgatgtcccttctggaagagagatgagt
gacagctgcgaaggtgcatttggtgggggaaagctggaaggcaaggccgcccggaaacat
caccgcaggtccacgcgtgtgcgctcccgccaggagagggccagtcggccccgactgacc
atcctgaacgtgtgcaacacgggcgacaagatggtggagtgccagctggagacacacaac
cacaagatggtgacgttcaagtttgacctggatggggatgcgcctgacgagatcgctacc
tacatggtggagcacgacttcatcctgcaggccgagcgggagacattcattgagcagatg
aaggatgtcatggacaaggcagaggatatgctcagtgaggacacggatgtggaccgtgcc
tccgaccctggggtgagcccgccacacctcagcacctgtggcctgggtgctggggaggag
aatcgccaatcccaagcaaatgccccggtgtaccagcaaaatgtcctgcatactgggaag
aggtggtttatcatctgtccggtggccgagcacccagcagtagaggcccccgaatcttca
cccccacttcctctgagctccctgcagccagacaccagccaagattcagcaccctctaaa
gaccagctatcctccaaggagaaacccagcttctcaactgatctgcagcttctgagccaa
gcaggccccagggaccttcctggtggtgcaccagcccctttggtgccgtcatcccctccc
gtgactgctctgtcccaagacatggccccaccagctgccagtcctaagctggagccagca
acggggcctgccatgcaggcagggggatcaggaacccctcaggggccagccagtgagcat
aagactccctggccattaatggaaactcttgatgctcagcttgctgcacagtcccctggc
atgggccgagggccttgtgccccacctttggaggccccccttcaccccatgggtctgggg
gatcctgccttagccagagagcccatcaccaagggggagcccctggtgggctttgtggac
agcaccatcaagagcctggacgagaagctgaggactctgctctaccaggagcacgtgccc
acctcctcagcctccgccgggacccctgtagaggcaggtgaccgagacttcaccctggaa
cccccaagaggggatgagccccgtacagaggcctccgggggcagtttgggcctgctgccc
ccacctgcgttggaaaagtcagaaatggcccctggattagaggtcacactggagcagtcc
gtgtccttgtcagtgacagctgaatcatctttgagccacacgcttggccgtgagggagca
caagtggcctcagattcgcgcacagcacccagtgccccccaggatgtccctgcttctgcc
atccctgcccatctggagcccacagaccggaccagcagggtccctggggaaaccttggcc
gagtccatgcagagctgcctggggatgttgattgagggtggccaggacagccaaccccag
ccacacagcactctggtatcaggatcccctctgaagtggccagggcagcaggatggcagc
tcgccagccaaaaccgtgggccggttctcagtggtcagcacccaggatgagtggactctg
gcctcccccaatagcctgcggtactcagccccacctgacgtttacctggacgaggctccc
tgcagcccagacatgaagctggctgtgcggcgggcacagacggcctcctccatcgaggtc
ggcatggaagagcctttgtccagtgactctggggatgagtcccctcgcaggaggccttct
gtgcagaagcatgcctccctgcccagcagcagtggtggtgtggccagtgactttgtgaag
aaggccgctgccttcctgcagaggtcctctcgggctggctccccatgcctggagacacct
agcaggatgggtgtgaaggtccccaccatcagcgtgacctccttccactcccagtcatcc
tacatcagcagtgacaacgactcagagattgaggatgctgatatcaggaaagagctgcag
agtcttcgggagaagcatctgaaggagatctcagagctacaaagtcagcagaaacaggag
attgaggccctgtaccgccgcctaggcaagccgctaccccccaacttaggcctcttccac
acggccccacccattggccgccggagaaagaccagcaagagcaagctgaaggcggggaag
ttgctgagccccctggtgcagcagcttaaagtcgtggcctccagcacaggtcacttgtca
gactgcagcagagcccctcctgctaaggaccctgcccaagctggggcagggcccacagca
gcttcagacccatgtgggaaggcagttcagactcagcagccttgctccgtgcgggcctcc
ctgtctgcagacatctgctccggcttggccagtgatggaggcggagcgcacggcccaggc
tggacggtttaccacccaacgtctgagagagtgacctataagtctagtagcaaacctcgc
gctcgattcctcagtggacccgtgtctgtgtccatctggtctgccttgaagcgtctctgt
ctaggcaaagagcacagcagtcggtcctccaccagcagcctggtcccgggccctgagccg
ggcccccaacctgccctgcacatccaggcgcaggtgaacaacagcaacaacaagaaaggc
accttcacggacgatctgcacaagctggtggacgagtggacaagcaagacggtcggggcc
acaccactaaagccgtcactcaaccagttgaagcagacgcagaaattgcatgacatggag
gccacagcaggctggcccctggcctctggcgaggcacgggctatgaacacatctcgaaca
gcaatggggatgccatgtctggccccggtacccagccctgtacccaccgtggtcattcct
ggagctgcctcagcccttcctgtgcccatgccagattctgaaagtgagaagcccgactga

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