KEGG   Bison bison bison (American bison): 104990441
Entry
104990441         CDS       T08726                                 
Symbol
STAT3
Name
(RefSeq) signal transducer and activator of transcription 3 isoform X1
  KO
K04692  signal transducer and activator of transcription 3
Organism
bbis  Bison bison bison (American bison)
Pathway
bbis01521  EGFR tyrosine kinase inhibitor resistance
bbis04062  Chemokine signaling pathway
bbis04066  HIF-1 signaling pathway
bbis04068  FoxO signaling pathway
bbis04081  Hormone signaling
bbis04217  Necroptosis
bbis04550  Signaling pathways regulating pluripotency of stem cells
bbis04630  JAK-STAT signaling pathway
bbis04659  Th17 cell differentiation
bbis04917  Prolactin signaling pathway
bbis04920  Adipocytokine signaling pathway
bbis04931  Insulin resistance
bbis04933  AGE-RAGE signaling pathway in diabetic complications
bbis04935  Growth hormone synthesis, secretion and action
bbis05145  Toxoplasmosis
bbis05160  Hepatitis C
bbis05161  Hepatitis B
bbis05162  Measles
bbis05163  Human cytomegalovirus infection
bbis05167  Kaposi sarcoma-associated herpesvirus infection
bbis05169  Epstein-Barr virus infection
bbis05171  Coronavirus disease - COVID-19
bbis05200  Pathways in cancer
bbis05203  Viral carcinogenesis
bbis05205  Proteoglycans in cancer
bbis05206  MicroRNAs in cancer
bbis05207  Chemical carcinogenesis - receptor activation
bbis05212  Pancreatic cancer
bbis05221  Acute myeloid leukemia
bbis05223  Non-small cell lung cancer
bbis05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
bbis05321  Inflammatory bowel disease
bbis05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bbis00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    104990441 (STAT3)
   04066 HIF-1 signaling pathway
    104990441 (STAT3)
   04068 FoxO signaling pathway
    104990441 (STAT3)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    104990441 (STAT3)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    104990441 (STAT3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    104990441 (STAT3)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    104990441 (STAT3)
   04062 Chemokine signaling pathway
    104990441 (STAT3)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    104990441 (STAT3)
   04917 Prolactin signaling pathway
    104990441 (STAT3)
   04935 Growth hormone synthesis, secretion and action
    104990441 (STAT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    104990441 (STAT3)
   05206 MicroRNAs in cancer
    104990441 (STAT3)
   05205 Proteoglycans in cancer
    104990441 (STAT3)
   05207 Chemical carcinogenesis - receptor activation
    104990441 (STAT3)
   05203 Viral carcinogenesis
    104990441 (STAT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    104990441 (STAT3)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    104990441 (STAT3)
   05221 Acute myeloid leukemia
    104990441 (STAT3)
   05223 Non-small cell lung cancer
    104990441 (STAT3)
  09172 Infectious disease: viral
   05161 Hepatitis B
    104990441 (STAT3)
   05160 Hepatitis C
    104990441 (STAT3)
   05171 Coronavirus disease - COVID-19
    104990441 (STAT3)
   05162 Measles
    104990441 (STAT3)
   05163 Human cytomegalovirus infection
    104990441 (STAT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    104990441 (STAT3)
   05169 Epstein-Barr virus infection
    104990441 (STAT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    104990441 (STAT3)
  09163 Immune disease
   05321 Inflammatory bowel disease
    104990441 (STAT3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    104990441 (STAT3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    104990441 (STAT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    104990441 (STAT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    104990441 (STAT3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:bbis03000]
    104990441 (STAT3)
Transcription factors [BR:bbis03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    104990441 (STAT3)
SSDB
Motif
Pfam: STAT_alpha STAT_bind STAT_int STAT_linker SH2 E2R135 Baculo_PEP_C
Other DBs
NCBI-GeneID: 104990441
NCBI-ProteinID: XP_010840814
Ensembl: ENSBBBG00000011063
UniProt: A0A6P3HNP2
LinkDB
Position
Unknown
AA seq 770 aa
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL
LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA
TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK
SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL
ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ
HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY
QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN
GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY
NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS
GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST
KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM
DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSN
TIDLPMSPRTLDSLMQFGNNGEAAEPSAGGQFESLTFDMELTSECATSPM
NT seq 2313 nt   +upstreamnt  +downstreamnt
atggcccaatggaatcagctccagcagctggacacacggtacttggagcagctccatcag
ctgtacagtgacagcttccccatggagctgcggcagtttctggccccttggattgagagt
caagattgggcatacgcggccagcaaagaatcacatgcgactttggtgtttcataatctc
ttgggagaaattgaccaacagtatagccgcttcctgcaagagtccaatgttctctatcag
cacaatttgcgaagaatcaagcagttccttcagagcagataccttgagaagccaatggag
attgcccgaattgtggcccgttgcctgtgggaagagtcccgcctcctccaaactgcagcc
actgcagcccagcaagggggccaggccaaccaccccacagccgccgtggtaacggagaag
cagcagatgctggagcagcacctgcaggacgtccgcaagcgtgtccaggatctagaacag
aagatgaaagtggtagagaatctccaggatgatttcgatttcaactataaaactctcaag
agtcaaggagacatgcaagatctgaatggaaacaaccagtcggtgaccaggcagaagatg
cagcagctcgaacagatgcttactgccctggaccagatgcggcgcagcatcgtgagtgag
ctggcggggcttttgtcagcgatggagtatgtgcagaaaactctcacggatgaagaattg
gctgactggaagaggcgacaacagattgcttgcattggaggccctcccaacatctgccta
gatcggctagaaaactggataacctcattagcagaatctcagcttcagacccgccaacaa
attaagaaactggaggagctgcagcagaaggttagctacaaaggggaccccattgtacag
caccggccaatgctggaggagagaatcgtggagctgtttagaaacttaatgaaaagtgcc
tttgtggtagagcggcagccctgcatgcctatgcatcctgaccggccattagtcatcaag
accggtgtccagttcacaactaaagtcagattgctggttaaattccctgagctaaattat
caacttaagattaaagtgtgcattgacaaagactccggggacgttgcagctctcagaggg
tcccgaaaatttaacattctgggcacaaacacgaaagtgatgaacatggaagagtctaac
aatggcagcctctcagcggagttcaaacacttgaccctgagagagcagagatgcggtaat
gggggccgagccaattgtgatgcctccctgattgtgaccgaggagctgcacctgatcacc
tttgagactgaggtgtatcaccaaggcctcaagattgacctggagacccactccttgcca
gtggtggtgatctccaacatctgtcagatgcccaatgcctgggcgtccatcctatggtac
aacatgctgaccaacaaccccaagaacgtgaactttttcaccaaacccccgatcggaacg
tgggatcaagtggccgaggtgctgagctggcagttctcctctaccaccaagcgcgggctg
agcatcgagcagttgacgacgctggcggagaaactcttaggacctggtgtgaactattca
gggtgtcagatcacatgggctaaattttgcaaagaaaacatggctggcaagggcttctcc
ttctgggtctggctggacaacatcattgacctggtgaaaaagtacatcctggccctttgg
aacgaagggtatataatgggcttcatcagcaaggagagggaacgggccatcttgagcact
aagcccccaggtaccttcctgctgagattcagtgaaagcagcaaagaaggaggcgtcacc
ttcacctgggtggagaaggacatcagtggcaagacccagatccagtcagtggaaccttac
accaagcagcagctgaacaacatgtcatttgctgaaataatcatgggctataagatcatg
gatgccaccaatatcctggtgtctccactggtctatctctaccctgacattccaaaggag
gaggcgttcggaaagtactgtcggccggagagccaggagcatcctgaagccgacccaggt
agtgctgccccgtacctgaagaccaagttcatctgtgtgacaccaacgacctgcagcaat
accattgacctgccgatgtccccccgcactttagattcattgatgcagtttggaaataat
ggtgaagctgctgaaccctcagcaggagggcagtttgagtccctcacgttcgacatggag
ctgacctcggagtgcgctacctcccccatgtga

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