Bubalus bubalis (water buffalo): 102403092
Help
Entry
102403092 CDS
T05912
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X2
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
bbub
Bubalus bubalis (water buffalo)
Pathway
bbub01521
EGFR tyrosine kinase inhibitor resistance
bbub01522
Endocrine resistance
bbub04010
MAPK signaling pathway
bbub04014
Ras signaling pathway
bbub04015
Rap1 signaling pathway
bbub04066
HIF-1 signaling pathway
bbub04068
FoxO signaling pathway
bbub04114
Oocyte meiosis
bbub04140
Autophagy - animal
bbub04144
Endocytosis
bbub04150
mTOR signaling pathway
bbub04151
PI3K-Akt signaling pathway
bbub04152
AMPK signaling pathway
bbub04211
Longevity regulating pathway
bbub04213
Longevity regulating pathway - multiple species
bbub04510
Focal adhesion
bbub04520
Adherens junction
bbub04550
Signaling pathways regulating pluripotency of stem cells
bbub04730
Long-term depression
bbub04913
Ovarian steroidogenesis
bbub04914
Progesterone-mediated oocyte maturation
bbub05200
Pathways in cancer
bbub05202
Transcriptional misregulation in cancer
bbub05205
Proteoglycans in cancer
bbub05214
Glioma
bbub05215
Prostate cancer
bbub05218
Melanoma
bbub05224
Breast cancer
bbub05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102403092 (IGF1R)
04014 Ras signaling pathway
102403092 (IGF1R)
04015 Rap1 signaling pathway
102403092 (IGF1R)
04066 HIF-1 signaling pathway
102403092 (IGF1R)
04068 FoxO signaling pathway
102403092 (IGF1R)
04151 PI3K-Akt signaling pathway
102403092 (IGF1R)
04152 AMPK signaling pathway
102403092 (IGF1R)
04150 mTOR signaling pathway
102403092 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
102403092 (IGF1R)
04140 Autophagy - animal
102403092 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
102403092 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
102403092 (IGF1R)
04520 Adherens junction
102403092 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
102403092 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
102403092 (IGF1R)
04914 Progesterone-mediated oocyte maturation
102403092 (IGF1R)
09156 Nervous system
04730 Long-term depression
102403092 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
102403092 (IGF1R)
04213 Longevity regulating pathway - multiple species
102403092 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102403092 (IGF1R)
05202 Transcriptional misregulation in cancer
102403092 (IGF1R)
05205 Proteoglycans in cancer
102403092 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
102403092 (IGF1R)
05214 Glioma
102403092 (IGF1R)
05218 Melanoma
102403092 (IGF1R)
05215 Prostate cancer
102403092 (IGF1R)
05224 Breast cancer
102403092 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102403092 (IGF1R)
01522 Endocrine resistance
102403092 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bbub01001
]
102403092 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
bbub04090
]
102403092 (IGF1R)
Enzymes [BR:
bbub01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
102403092 (IGF1R)
Protein kinases [BR:
bbub01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
102403092 (IGF1R)
CD molecules [BR:
bbub04090
]
Proteins
102403092 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
fn3
Kinase-like
DUF4476
Insulin_TMD
Motif
Other DBs
NCBI-GeneID:
102403092
NCBI-ProteinID:
XP_025127352
EnsemblRapid:
ENSBBUG00015021210
LinkDB
All DBs
Position
20:complement(62263123..62570332)
Genome browser
AA seq
1367 aa
AA seq
DB search
MKSSSGGGSPTSLWGLLFFSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAASNNYIVGNKPPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTETHECCHPECLGSCS
APDNATACVACRHYYYAGVCVPSCPPNTYRFEGWRCVDRDFCANIPNAESSDSEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNAIFVPRPERKRREVMQIANTTMSSRGRNTTVLDTYNITDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
EPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVQAKTTYENFIHLIIALPIAVLLIVGGLVMMLYVFHR
KRNSSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIISSVKDEMEAGFREVSFYYSEENKPPEPEELDLEPENMESVPLDPSASSASLPLPDRH
SGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
4104 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctagctccggaggagggtccccgacctcgctgtggggactcctgtttttctcc
gccgcgctctcgctctggcccacgagtggagaaatctgcgggccgggcatcgacatccgc
aacgactaccagcagctgaagcgcctggagaactgcacggtgattgagggctacctccac
atcctgctcatttccaaggccgaggactaccgcagctaccgcttccccaagctcaccgtc
atcaccgagtacctgctgctgttccgcgtggccggcctcgagagcctgggcgacctcttc
cccaacctcacggtcatccgcggctggaagctcttctacaactacgccctggtcatattc
gagatgaccaacctcaaagacatcgggctctacaacctgcggaatatcacccgtggggcc
atccggatcgagaagaatgccgacctctgctacctgtccacggtggactggtccctgatc
ctggatgcggcatccaacaactacatcgtggggaacaagccccccaaggagtgtggggac
ctgtgtccggggacgatggaggagaagccgctgtgcgagaagacgaccatcaacaacgag
tacaactaccgctgctggaccacaaaccgctgccagaaaatgtgccccagcgcgtgcggg
aagcgggcatgcacggagacccacgagtgctgccaccccgagtgcctaggcagctgcagc
gcgcccgacaacgctacggcctgcgtggcctgccgccactactactacgccggcgtctgc
gtgcccagctgcccgcccaacacctaccgcttcgagggctggcgctgcgtggaccgcgac
ttctgcgccaacatccccaacgccgagagcagcgactccgagggcttcgtcatccacgac
ggcgagtgcatgcaggagtgcccgtcgggcttcatccgcaacgggagccagagcatgtac
tgcatcccttgcgaaggcccttgtcccaaagtgtgtgaggaagaaaagaagacaaagacc
attgattctgtcacttctgctcagatgctccaaggatgcaccatcttcaaaggcaatctg
ctcatcaacatccgtcgcggcaacaacatcgcttcggaactggagaacttcatggggctc
atcgaggtggtgacgggctacgtgaagatccgccactcccacgccttggtctccttgtcc
ttcctgaagaacctgcgccagatcctaggggaggagcagctagaggggaactactccttc
tatgtccttgacaaccagaacttgcagcagctgtgggactgggaccaccgcaacctgacc
atcaaagctgggaaaatgtactttgcattcaatcccaaattgtgtgtctcggagatttac
cgcatggaggaagtgacggggactaaagggcgccagagcaaaggggacataaacaccagg
aacaacggggagagagcctcctgtgaaagtgacgtcctgcacttcacctccaccaccacg
tcgaagaaccgaatcatcatcacctggcaccggtaccggccccccgactaccgggacctc
atcagcttcactgtctactacaaggaagccccctttaaaaacgtcacggagtatgacggg
caggacgcctgcggctccaacagctggaacatggtggacgtggaccttccgcccaacaag
gacgtggagcccggcattttgctgcacgggctgaagccctggacgcagtacgccgtttac
gtgaaggccgtgaccctcaccatggtggagaacgaccacattcgtggggccaagagcgag
atcttgtacattcgcaccaacgcatcagttccttccatccccctggatgtcctctcggcc
tcaaactcctcttctcagctgatcgtgaagtggaacccgccctccctgcccaacggcaac
ctgagctactacatcgtgcgctggcagcgccagccccaggacagctacctgtaccggcac
aactactgctccaaagacaaaatccccatcaggaagtacgccgacggcaccatcgacgtc
gaggaggtgacggagaaccccaagaccgaggtgtgcggcggggagaaagggccgtgctgc
gcttgccccaaaaccgaagctgagaagcaggcggagaaggaggaggccgagtaccgcaag
gtcttcgagaacttcctgcacaacgccatcttcgtgcccagacccgaacggaagcggagg
gaggtcatgcagattgccaacaccaccatgtccagccggggcaggaacaccacggtgctg
gacacctacaacatcacagacccggaagagctcgagaccgagtaccctttctttgagagc
agagtggacaacaaggagagaactgtcatctccaacctccggccttttactctgtaccga
atcgacatccacagctgtaaccatgaggctgagaagcttggctgcagcgcttccaacttt
gtctttgcaagaaccatgcctgcagaaggagcagacgacattcctgggccggtgacctgg
gagccaaggcctgagaactccatctttttaaaatggccagaacctgagaatcccaatgga
ttgatcctcatgtatgaaataaaatatggatcccaagtcgaggatcagcgggaatgtgtg
tccagacaggagtataggaagtatggaggagccaagctaaaccggctcaacccagggaac
tacacagcccggatccaggccacctctctctctgggaatgggtcgtggacggatcccgtg
ttcttctacgttcaggccaagacgacatatgagaacttcatccacctgatcatcgctctg
cccattgcggttctgttgatagtgggaggcttggttatgatgctgtacgtcttccataga
aaaagaaatagcagcaggctgggaaatggagtgctgtacgcctctgtgaacccggagtat
ttcagcgcagctgatgtgtacgtgcctgacgagtgggaggtggcccgggagaagatcacc
atgagccgcgagctgggccagggctccttcgggatggtctacgaaggcgtggccaagggc
gtggtcaaggatgagcccgagaccagggtggccattaagacggtgaacgaggccgccagc
atgcgcgagcggatcgagtttctcaatgaggcctcggtgatgaaggagttcaattgtcac
cacgtggtgcgcttgctgggcgtggtgtcccagggccagccgacgctggtcatcatggaa
ctgatgacccggggggacctcaagagttatctccggtctctgaggccagaaatggagaat
aatccagtcctagcacctcccagcctaagcaaaatgatccagatggctggtgagattgca
gacggcatggcatacctcaacgccaataagtttgtccacagagacctcgctgcccggaac
tgcatggtggccgaagatttcacagtcaaaatcggagattttgggatgacaagagacatc
tatgagacggactattaccggaagggggggaaggggctgctgcccgtccgctggatgtcc
cccgagtccctcaaggacggagtcttcaccactcactctgacgtctggtcctttggggtc
gtcctctgggagatcgccacgctggctgagcagccgtatcagggcctgtccaacgagcag
gtccttcgcttcgtcatggagggcggccttctggacaagccggacaactgtcctgacatg
ctgtttgagctgatgcgcatgtgctggcagtacaaccccaagatgcggccttcgttcctg
gagatcatcagcagcgtcaaggacgagatggaggcgggcttccgggaggtctccttctac
tacagcgaggagaacaagccgccggagccggaggagctggacctggagcccgagaacatg
gagagcgtgccgctggacccctcggcctcctcggcctccctgccgctgcccgacagacac
tcaggacacaaggccgagaacggcccgggcccgggcgtgctggtcctgagggccagcttc
gacgagaggcagccctacgcgcacatgaacgggggccgcaagaacgagcgcgccctgccg
ctgccccagtcctccacctgctga
DBGET
integrated database retrieval system
