KEGG   Bubalus bubalis (water buffalo): 102403837
Entry
102403837         CDS       T05912                                 
Symbol
WNK2
Name
(RefSeq) serine/threonine-protein kinase WNK2 isoform X1
  KO
K08867  WNK lysine deficient protein kinase [EC:2.7.11.1]
Organism
bbub  Bubalus bubalis (water buffalo)
Pathway
bbub04928  Parathyroid hormone synthesis, secretion and action
Brite
KEGG Orthology (KO) [BR:bbub00001]
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    102403837 (WNK2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bbub01001]
    102403837 (WNK2)
   01009 Protein phosphatases and associated proteins [BR:bbub01009]
    102403837 (WNK2)
Enzymes [BR:bbub01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     102403837 (WNK2)
Protein kinases [BR:bbub01001]
 Serine/threonine kinases: Other
  Wnk family
   102403837 (WNK2)
Protein phosphatases and associated proteins [BR:bbub01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     102403837 (WNK2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr CCTL2_WNK OSR1_C
Other DBs
NCBI-GeneID: 102403837
NCBI-ProteinID: XP_045021069
LinkDB
Position
3:146151640..146294237
AA seq 2178 aa
MDDDGGRRNAPGALMEAGRGAGPAGMAEPAAVPRVRAARPGPQRFLRRSVVESDQEEPPG
LEAAEAPGAQPPQPLQRRVLLLCKTRRLIAERARGRPAAPLPAAPAAPPSNLADPGLEPA
GAQEPCPDPAPVPVPAPDGGPREEIAATRKEDAGAPEARPELGRARREEPEEEEDDEDDL
KAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEA
EMLKGLQHPNIVRFYDFWESSARGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCR
QILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEF
MAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKVHD
PEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWVEDP
KKLKGKPKDNGAIEFTFDLERETPDDVAQEMIESGFFHESDVKIVAKSIRDRVALIQWRR
KRIWPALQPQEQRELGSPDKARGPPTPLQVQVTYHSQAGLPESEEPEADQHLLTPALPAS
ATSLASDSTFDSGQGSTVYSDSQSSQQSVVLGSLADGAPPPSQCVCSPPVSVSDGPVLPH
SLPSLGAYQQPATPGLSVGSVPPPTHPPLPQQPFPEPAMSFAPVLPPPSAPVPTGPGQPT
APAHQPSLLAQPVPLPQVLAPQPVGPLQPAPSHLPPYLAPTSQVVAPAQLKPLQMPPVPL
QPLAQIPPQMPPLPVVPPIAPLATVDSLPTALPDLPATSGPTVPPPSQYFSPAVILPSLP
LNATTASLPASPALPLQTVKLPHPAGTPLAVPCRTIVPNVAATATAIPLLAVAPQGVAAL
SIHPTVAQLPAQPVYPAAFPQMVPSDVPPSPLHAAQTVPAAAPQPTPTVLPQPHQPSVAR
LPEQAAPAASAGSQILLGHPPTYAVDVTTQVATVPAPAAVLSPPLPEVLLPPAPELLPQL
PGSLAPTVMAAPQSVPVQTAALLPPANLPLPSGPGIPGPCPTVQLTVEPAPEEQASQDKQ
PSLPQSCESYGGSDVPSGREMSDSCEGAFGGGKLEGKAARKHHRRSTRVRSRQERASRPR
LTILNVCNTGDKMVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIE
QMKDVMDKAEDMLSEDTDVDRASDPGVSPPHLSTCGLGAGEENRQSQANAPVYQQNVLHT
GKRWFIICPVAEHPAVEAPEASPPLPLSALQPDTSQDSAPSKDQLSSKEKPSFSTDLQLL
SQAGPRDLPGGAPAPLVPSSPPVTALSQDMAPPAASPKLEPATGPAMQTGGPGTPQGPAS
EHKTPWPLMETLDVQLAAQSPGMGRGPCAPPLEAPLHPMGLGDPALAREPITKGEPLSAL
APTSGAPGGASQPTVSQPLPPLPTVVGAISLATPQLPSPPLAPTAPPQPPSTLESDGEGP
PPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEAGDRDFTLEPPRGDEPRTEAS
GGSLALLPQPALEKSEVAPGLEVTLEQSMSLSVTAESSLSHTLGREGAQVASDSRAAPSA
PKDVPASAIPAHLEPTDRTSRVPGETLAESMQSFPGTLIEGGQDSQPQPHSTLVSGSPPK
WPGQQDGSSPAKTVGRFSVVSTQDEWTLASPNSLRYSAPPDVYLDEAPCSPDMKLAVRRA
QTASSIEVGMEEPLSSDSGDESPCRRPSVQKHASLPSSSGGVASDFVKKAAAFLQRSSRA
GSPGLETPSRMGVKVPTISVTSFHSQSSYISSDNDSEIEDADIRKELQSLREKHLKEISE
LQSQQKQEIEALYRRLGKPLPPNLGLFHTAPPIGRRRKTSKSKLKAGKLLSPLVQQLKVV
ASSTGHLSDCSRAPPAKDPAQAGAGPTAASDPCGKAVQTQQPCSVRASLSADICSGLASD
GGGAHGPGWTVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTS
SLVPGPEPGPQPALHIQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGATQLKPSLNQLKQ
TQKLHDMEATAGWPLASGEARAILKVRSPTEPRQADPDPDARPCVISRREGEPTPRVRFT
MFCNHFLSIFYSQLETQM
NT seq 6537 nt   +upstreamnt  +downstreamnt
atggacgacgatggcggccgccgaaacgccccgggcgcactgatggaggccgggcgcggt
gcgggtcccgcgggcatggcggagcccgcggcagtgccgcgggtgcgggcggcgcggccg
gggccccagcgcttcctgcggcgcagcgtggtggagtctgatcaggaggagccgccgggc
ctggaggctgccgaggcgccgggcgcgcagcccccgcagccgctgcagcgcagggtgctg
ctgctatgcaagacgcgccgcctcattgccgagcgcgcccgaggtcgcccggccgcccca
ttgcctgccgcgcctgctgcgccgccgagcaaccttgccgaccccggcctggagccggcg
ggagcgcaggaaccctgcccggaccccgcgccagttccggtgcccgcccccgacggcggt
ccccgtgaggagatagcggccacgaggaaggaggacgcgggggctcccgaggccaggccg
gagctcgggcgcgcacgccgggaggagcccgaggaggaggaagacgacgaggacgacctg
aaggctgtggccacctccctggatggccggttcctcaagtttgacattgagcttggccgc
ggctctttcaagacggtctataaagggctggatacggagacctgggtggaagtagcctgg
tgcgagctgcaggaccggaagctcaccaaactggagaggcagcggttcaaggaggaggcc
gagatgctgaaaggcctgcagcaccccaacattgtgcgcttctatgacttctgggagtcc
agtgccagggggaagcggtgcatcgtgctggtgaccgaactgatgacctcggggacactg
aagacgtatctgaagcggttcaaggtgatgaagcccaaggttctacgtagctggtgccgg
cagatcctgaagggcctgctgttcctgcacaccaggacgccccccatcatccaccgggac
ctcaagtgtgacaacatctttatcactgggcccacagggtctgtgaagatcggcgacttg
ggcctggccaccctcaagagagcatcctttgctaaaagcgtgataggtacccccgagttc
atggcaccagagatgtacgaggagcactacgatgagtctgtggacgtgtacgccttcggg
atgtgcatgttggagatggccacctcagagtacccctactcagagtgccagaatgccgcc
cagatctacaggaaggtcacctgtggcatcaagccagccagctttgagaaagtgcacgat
cctgaaatcaaggagattattggggagtgtatctgcaaaaacaaggaggaaaggtatgag
atcaaggacctgctcagccacgccttcttcgcggaggacacaggtgtgagggtggagctg
gccgaggaggaccatggcaggaagtccaccattgccctgcggctctgggttgaggaccct
aagaaactgaagggcaagcccaaggacaacggggccatagagttcaccttcgacctggag
agggagacgccagatgacgtggcacaggaaatgattgagtcaggatttttccatgagagt
gacgtgaagattgtggccaagtccatccgtgaccgtgtggcattgatccagtggcggcga
aagaggatctggccagcgctgcagccccaggagcagcgggagctcggcagccctgacaag
gccaggggcccacccacgcccctgcaggtccaggtgacctaccactcgcaggccgggctg
ccagagtccgaggagcccgaggccgaccagcacctcctcacccctgcgctgccggccagc
gccacctccctggcctcggacagcacgttcgacagtggccagggctccacggtgtattca
gactcgcagagtagccagcagagtgttgtgctggggtcgctggcagacggagcaccaccc
ccctcccagtgtgtgtgcagcccccctgtgagcgtgagtgatgggcccgtcctgccacat
agcctgccctccctgggggcctaccagcagcctgccacgcctggcctgtcggtgggctct
gtcccaccccccacccaccctccgctcccacagcagcctttcccagagccagccatgagc
ttcgcccctgtactgccaccgcccagtgcccctgtgccgacaggccctggccagcccaca
gcccccgcccaccagccttctctcctggcccagccggtacccttgccgcaggtcctggcc
ccacaacccgtgggccctctgcagccagcgccctcccacctgcctccgtacctggctcca
acctcccaggtggtggcccctgctcagctgaagcccctccagatgcctccagtgcccctg
cagccactagctcaaatccccccgcagatgcctccacttcctgttgtcccccccatcgct
ccactggccacagttgacagcctccccacagcccttcctgacctgccagccaccagtggg
cccaccgtgcctcccccctctcagtatttctctccagctgtcatcttgccaagcctccca
ctcaatgccaccaccgcttccctgcctgcgtcgccggctctgcctctgcagacggtcaag
ctgcctcaccctgctgggacaccgctggccgtgccgtgccggaccatcgtgccaaatgtg
gcggccactgccaccgccatccctctgctggctgtggccccacagggcgtggccgccctg
tccattcaccccactgtggcccagctcccggcacagcccgtgtacccagcggcctttccg
cagatggtacccagcgacgtcccgccttctcccctccacgcagcgcagactgtgccggct
gccgctccccagccgacacccaccgtgctgccacagccccaccagccaagtgttgcccgc
ctcccggagcaggctgctccggccgccagtgctggaagccagatcctgcttggccacccg
cctacatatgctgtggatgtcaccacccaggtcgccacagtgcccgcacctgctgctgtt
ctctccccacctctgccggaagtgctgctgcctcctgcccccgagctcctgcctcagctc
cccggctctctggcccccacagtgatggcggctcctcagagcgtgcctgtccagaccgct
gcactcctgccgcctgctaacctgccgctgcccagtgggcctgggatccctggtccctgc
ccgactgttcagctgacggtggagccagcccccgaggagcaggcctcacaggacaagcag
cccagcctccctcagagctgtgagagctatggaggctctgacgtcccttctggaagagag
atgagtgacagctgcgaaggtgcatttggtgggggaaagctggaaggcaaggccgcccgg
aaacatcaccgcaggtccacgcgtgtgcgctcccgccaggagagggccagtcggccccga
ctgaccatcctgaatgtgtgcaacacgggtgacaagatggtggagtgccagttggagaca
cacaaccacaagatggtgacgttcaagtttgacctggatggggatgcacctgacgagatt
gctacctacatggtagagcacgacttcatcctgcaggccgagcgggagacattcattgag
cagatgaaggatgtcatggacaaggcagaggatatgctcagtgaggacacggatgtggac
cgtgcctccgaccctggggtgagcccgccacacctcagcacctgtggcctgggtgctggg
gaggagaatcgccaatcccaagcaaacgccccggtgtaccagcaaaatgtcctgcacact
gggaagaggtggtttatcatctgtccggtggctgagcacccagcagtagaggcccccgaa
gcttcacccccacttcctctgagcgccctgcagccagacaccagccaagattcagcaccc
tctaaagaccagctatcctccaaggagaaacccagcttctcaactgatctgcagcttctg
agccaagcaggccccagggaccttcctggtggtgcaccagcccctttggtgccgtcatcc
cctcccgtgactgctctgtcccaagacatggccccaccagctgccagtcctaagctggag
ccagcaacggggcctgccatgcagacagggggaccaggaacccctcaggggccggccagt
gagcataagactccctggccattaatggaaactcttgatgttcagcttgctgcacagtcc
cctggcatgggccgagggccttgtgccccacctttggaggccccccttcaccccatgggt
ctgggggatcctgccttagccagagagcccatcaccaagggggagcccctatcagctttg
gcccccacatctggtgcccctggcggggcctctcagcccactgtgagccagccccttccc
ccgctccctactgtggtgggagcaatcagtctggccactccccagctccccagtcccccg
ctggcacccactgccccacctcagccaccttcaaccttggagtcagatggagaagggccg
cccccaagggtgggctttgtggacagcaccatcaagagcctggacgagaagctgaggact
ctgctctaccaggagcacgtgcccacctcctcagcctcggctgggacccctgtggaggca
ggtgaccgagacttcaccctggaacccccaagaggggatgagccccgtacagaggcctct
gggggcagtctggccctgctgccccagcctgcgttggaaaagtcagaagtggcccctgga
ttagaggtcacactggagcagtccatgtccttgtcagtgacagctgaatcatctttgagc
cacacgcttggccgtgagggagcacaggtggcctccgattcgcgcgcagcacccagtgcc
cccaaggatgtccctgcttctgccatccctgcccatctggagcccacagaccggaccagc
agggtccctggggaaaccttggccgagtccatgcagagcttcccggggacattgattgag
ggtggccaggacagccaaccccagccacacagcactctggtatcaggatcccctccgaaa
tggccagggcagcaggatggcagctcgccagccaaaaccgtgggccggttctcagtggtc
agcacccaggatgagtggactctggcctcccccaatagcctgcggtactcagccccacct
gacgtttacctggacgaagctccctgcagcccagacatgaagctggctgtgcggcgggca
cagacggcctcctccatcgaggtcggcatggaagagcccttgtccagtgactctggggac
gagtccccttgcaggaggccttctgtgcagaagcatgcctccctgcccagcagcagtggt
ggtgtggccagtgactttgtgaagaaggccgctgccttcctgcagaggtcctctcgggct
ggctccccaggcctggagacacccagcaggatgggcgtgaaggtccccaccatcagcgtg
acctccttccactcccagtcatcctacatcagcagtgacaacgactcagagattgaggat
gctgatatcaggaaagagctgcagagccttcgagagaagcatctgaaggagatctcagag
ctacaaagtcagcagaaacaggagattgaggccctgtaccgccgcctaggcaagccacta
ccccccaacttaggcctcttccacacggccccacccattggccgccggagaaagaccagc
aagagcaagctgaaggcggggaagttgctgagccccctggtgcagcagctcaaagtcgtg
gcctccagcacaggtcacttgtcagactgcagcagagccccacctgctaaggaccctgcc
caagctggggcagggcccacagcagcttcagacccatgtgggaaggcagttcagactcag
cagccttgctccgtgcgggcctccctgtctgcagacatctgctccggcttggccagtgat
ggaggcggagcgcacggcccaggctggacggtttaccacccaacgtctgagagagtgacc
tataagtctagtagcaaacctcgcgctcgattcctcagtggacccgtgtctgtgtccatc
tggtctgccttgaagcgtctctgtctaggcaaagagcacagcagtcggtcctccaccagc
agcctggtcccgggccctgagccgggcccccaacctgccctgcacatccaggcgcaggtg
aacaacagcaacaacaagaaaggcaccttcacggatgacctgcacaagctggtggacgag
tggacaagcaagacggtcggggccacacaactaaagccgtcactcaaccagttgaagcag
acacagaaattgcatgacatggaggccacagcaggctggcccctggcctctggcgaggca
cgggctattctgaaagtgagaagcccgactgagcccaggcaggccgacccagacccagac
gccaggccctgtgtcatctcacgcagagaaggcgagcccacgcctcgtgtccggttcacg
atgttttgtaatcactttctaagcattttttattcacaattggaaacacaaatgtaa

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