KEGG   Bos indicus (zebu cattle): 109554414
Entry
109554414         CDS       T04792                                 
Symbol
PPP1CA
Name
(RefSeq) serine/threonine-protein phosphatase PP1-alpha catalytic subunit
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
biu  Bos indicus (zebu cattle)
Pathway
biu03015  mRNA surveillance pathway
biu04022  cGMP-PKG signaling pathway
biu04024  cAMP signaling pathway
biu04114  Oocyte meiosis
biu04218  Cellular senescence
biu04261  Adrenergic signaling in cardiomyocytes
biu04270  Vascular smooth muscle contraction
biu04390  Hippo signaling pathway
biu04510  Focal adhesion
biu04611  Platelet activation
biu04720  Long-term potentiation
biu04728  Dopaminergic synapse
biu04750  Inflammatory mediator regulation of TRP channels
biu04810  Regulation of actin cytoskeleton
biu04910  Insulin signaling pathway
biu04921  Oxytocin signaling pathway
biu04931  Insulin resistance
biu05031  Amphetamine addiction
biu05034  Alcoholism
biu05168  Herpes simplex virus 1 infection
biu05205  Proteoglycans in cancer
biu05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:biu00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    109554414 (PPP1CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    109554414 (PPP1CA)
   04024 cAMP signaling pathway
    109554414 (PPP1CA)
   04022 cGMP-PKG signaling pathway
    109554414 (PPP1CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    109554414 (PPP1CA)
   04218 Cellular senescence
    109554414 (PPP1CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    109554414 (PPP1CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    109554414 (PPP1CA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    109554414 (PPP1CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    109554414 (PPP1CA)
   04921 Oxytocin signaling pathway
    109554414 (PPP1CA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    109554414 (PPP1CA)
   04270 Vascular smooth muscle contraction
    109554414 (PPP1CA)
  09156 Nervous system
   04728 Dopaminergic synapse
    109554414 (PPP1CA)
   04720 Long-term potentiation
    109554414 (PPP1CA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    109554414 (PPP1CA)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    109554414 (PPP1CA)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    109554414 (PPP1CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    109554414 (PPP1CA)
   05034 Alcoholism
    109554414 (PPP1CA)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    109554414 (PPP1CA)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    109554414 (PPP1CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:biu01009]
    109554414 (PPP1CA)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:biu03021]
    109554414 (PPP1CA)
   03019 Messenger RNA biogenesis [BR:biu03019]
    109554414 (PPP1CA)
   03041 Spliceosome [BR:biu03041]
    109554414 (PPP1CA)
Enzymes [BR:biu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     109554414 (PPP1CA)
Protein phosphatases and associated proteins [BR:biu01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     109554414 (PPP1CA)
Transcription machinery [BR:biu03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     109554414 (PPP1CA)
Messenger RNA biogenesis [BR:biu03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     109554414 (PPP1CA)
Spliceosome [BR:biu03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    109554414 (PPP1CA)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 109554414
NCBI-ProteinID: XP_019810439
UniProt: A0ABM4RTA1
LinkDB
Position
29:complement(47365364..47378604)
AA seq 330 aa
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
KNKGKYGQFSGLNPGGRPITPPRNSAKAKK
NT seq 993 nt   +upstreamnt  +downstreamnt
atgtccgacagcgagaagctcaacctggactctataatcggacgcctgctggaagtgcag
ggctccaggcctggaaagaatgtacagctgacggagaacgagatccgtggtctgtgcctc
aaatcccgggagattttcctgagccagcccattcttctggagctggaggcacccctcaag
atctgcggtgacattcacggccagtactatgatcttctgcggctgttcgagtacggtggc
ttccctccagagagtaactacttgttcctgggggactacgtggacaggggcaagcagtct
ttggagaccatctgcctgctgctggcctataagatcaagtacccagagaacttcttcctg
ctccgtgggaaccacgagtgtgccagcatcaaccgcatctacggcttctatgatgagtgc
aagagacgctacaacatcaaactgtggaagaccttcactgattgcttcaactgcctgccc
atcgctgccatcgtggacgagaagatcttctgttgccatggagggctgtccccagaccta
cagtccatggagcagatccggcgtatcatgcggcccacagatgtgcctgaccagggcctg
ctctgtgacctgctgtggtctgaccctgacaaggacgtgcagggctggggygagaatgac
cgcggcgtctcctttacatttggagctgaggtggtggccaagttcctgcacaagcatgac
ctggacctcatctgccgggcacaccaggtagtagaagacggctatgagttctttgccaag
cggcagctggtgacactcttttcagcccccaactactgcggcgagtttgacaatgcaggt
gccatgatgagtgtggacgagacgctcatgtgctccttccagatcctcaagcccgctgac
aagaacaaggggaaatacgggcagttcagtggcctgaaccctggaggccggcccatcacc
ccaccccgcaactccgccaaagccaagaaatag

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