Bubalus kerabau (carabao): 129622753 Help Entry 129622753         CDS       T11435                                  Symbol OBSCN Name (RefSeq) obscurin isoform X1   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism bke  Bubalus kerabau (carabao) Pathway bke04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:bke00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     129622753 (OBSCN)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:bke01001]     129622753 (OBSCN)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:bke04131]     129622753 (OBSCN) Enzymes [BR:bke01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      129622753 (OBSCN) Protein kinases [BR:bke01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    129622753 (OBSCN) Membrane trafficking [BR:bke04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     129622753 (OBSCN) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Other DBs NCBI-GeneID:  129622753 NCBI-ProteinID:  XP_055395324 LinkDB All DBs Position 1:complement(172129695..172368229) Genome browser AA seq 9617 aa AA seqDB search MDHSSFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDRQLVEAGGRFRLAQ DGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDADAACAEQAPHFLLRPTSIR VREGAEATFRCRVRGSPPMSVSWAKDGRRLGALDAPRVRVEESGEASALRIRAAQPRDSG TYTVHAENPLGAASAAAGLTVDAEAEAANPPGASTAMLLAHLQRRREAMRAGGAPASPPS AGTRTCTVTEGKHARLSCFVTGEPKPEIVWKKDGQLVVEGRRHVVYEDEQENFVLKILFC KQSDCGLYTCTASNLVGQTYSSVLVVVREPTVPFRKRLQDLEVPEKASATFQCEVPVPAM ESAWYKEETRLWASEKYLIEEAGAERRLTVLNVSSDDDAVYICETAEGSRTVAELAVRGN LLRKLPRKTAVRVGDTAMFCVELAKPEGPVQWLWNRKAVVAGGRVAITAEGTCHTLTISQ CSLEDVGEVAFVAGDCRTSTQFCVSAPRRPPLHAPEAPVVKAQTESSVTLGWSPPPAGDR PAAIEGYLVEKKRLGAYTWSRCHEDEWVTTPELTVAGVAEEGEFQFRVSAVNSFGQSPYL EFPGTVHLAPQLAVKTPLKAVEAVEGGEVTFSVDLTTASSGEWFLDGRVLKASSVYVIRR DGTRHTLTIRSVPVSLHGAELKFVANGIESSIRMEVRAPLELTAKCPAPAAAAREVLARL HEEAQLLAELSDQAAAVTWLKDGHTLSPGPKYEVQASAGQRALLVRDVKREDAGLYECVS RGGRVAYQLLVQESSAVFIKGQPMHKEVKAVAGASATLSCEVAQAQTEVTWYKDGKKLSS SSKVHVEAKGCTRQLVVQQAGKADAGEYSCEAGGQKVSFHLDVAEPLVVFAKEQPARSEV QAVAGTSATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEAKGCTRRLVVQQAGKADAGEY SCEAGGQKVSFHLDVTEPSVVFAKEQPARSEVQAVAGASATLSCEVAQAQTEVTWYKDGK KLSSSSKVRVEATGRGRWLVVQQAGKADAGEYSCEAGGQKVSFHLDVTEPSVVFAKEQPA RSEVQAVAGTSATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEAKGCTRKLVVQQAGKAD AGEYSCEAGGQKVSFRLDVTEPSVVFAKEQPAHSEVQAMAGASATLSCEVAQAQTEVTWY KDGKKLSSSSKVRVEATGHGRRLVVQQAGKADAGEYSCEAGGQKVSFRLDVTEPSVVFAK EQPARSEVQAMAGTSATLNCEVAQAQTEVMWYKDGKKLSSSSKMRLEAKGCTRQLVVQQA GKADAGEYSCEAGGQKVSFRLDVTEPSVVFAKEQPARTEVQAVAGTSATLSCEVAQAQTE VTWYKEGKKLSSSSKVHVEAKGCTRRLVVQQAGKVDAGEYSCEAGGQKVSFHLDVTEPSV VFAKEQPARSEVQAVAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEATGRGRRLV VQQAGKADAGEYSCEAGGQKVSFRLDVTEPSVVFAKEQPACSEVQAVAGASATLSCEVAQ AQTEVTWYKDGKKLSSSSKVRVEATGRKRQLVVQQADKADAGEYSCEAGGQKVSFRLDVT EPSVVFAKEQPACSEVQAMAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEATGHG RRLVVQQAGKADAGEYSCEAGGQKVSFHLDVTEPSVVFAKEQPARSEVQAMAGASATLSC EVAQAQTEVTWYKDGKKLSSSSKVRVEAKGCTRKLVVQQAGKVDAGEYSCEAGGQKVSFH LDVTEPSVVFAKEQPARSEVQAVAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEA TGRGRRLVVQQAGKADAGEYSCEAGGQKVSFRLDVTEPSVVFAKEQLARSEVQAMAGASA TLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEAKGCTRRLVVQQAGKADAGEYSCEAGGQK VSFHLDVTEPLVVFAKEQPARSEVQAVAGASATLSCEVAQALTEVTWYKDGKKLSSSSKV RVEAKGCTRKLVVQQAGKADAGEYSCEAGGQKVSFHLDVAEPVVVFAKEQPARSEVQAKA GARTTLSCEVAQAQTEVTWYKDGKKLSSSSKVHVEAKGCTRQLVVQQAGKADAGEYSCEA RGQKVSFHLDVTEPEFEPPAPEKPRRREPLVVREHEDIVLTATLATPSVATVTWFKDGVE IRRSKRHEMTSLGDTHTLTMHGAQTLDSAVYSCRVGAEGQDFPVQVEEVAAKFCRPLEPV SGDLGGTATLVCELSPAQAEVVWRRGSTQLRSGKRFQMAAAGPRRSLTVSGLRAEDAGEY VCESRDDHTSAMLTVIVPRVVKFTSGLSAVVAEEGSEATFQCVVTPSDVAVTWFRDGVQL QSSEKFLISQKGASHSLTILSLALEDAGQVTAEAEGIQSTAALRVREAPVLFRKKLEPQT VEERSSVTMEVELTRPWPEVKWTRNAVALASGEKVEIHAEGARHRLVLHGVGFADRGFYG CETPDDKTQAKLTVEMRQVRLVRGLQAVEAQEQGTATMEVELSHADVEGNWTRDGLRLQP GPNCQLAVHGATHTLTLSRLQRQDGGLVAFRAEGVHTSAHLVVTELPVKFVRPLQDVVAT EKEKVALDCELSRPNVDVRWLKDNVELRVSKTMGMMAQGACRSLIIYRCELGDQGVYVCD AHDAQSSASLKVQGRNVQIVRPLDDVEVVEKEGATFSCKVSHDEVPAQWFWEGSKLRPSD NVRIRQEGRTYTLIYRRVLVEDAGEIKFVAENAESRAQLRVKELPVSILRPLRDKIAMEK HRGVLECQMSRASAQVRWFKGSVELHPGAKYEMVSDGLYRKLVINAVQPEDEDTYTCDAG DVKTSAQFFVEEQSIVVVRGLQDVTVMEPAPAWFECETSIPSVRPAKWLLGKTVLQAGPD VGIEQEGTVHRLTLRRTYSTMTGPVHFTIGKSRSTASLVVSDIPVVLTRPLEPKVGREMQ SVVLSCDFKPPPKAVQWYKEETPLAPSSKFKMRLEGHMAELRVLRLTPDDAGVYRCQAGS AQSSAEVTVEERKVTVTQPLEDVEVPEEGRACFSCELSHEDEEVDWLLNGTPLFNDSFHE ITHEGRRHTLVLKRVRQADRGTVSISSPKVAASAHLAVRGKPVVFLKALDDVSAEERGRL TLQCEVSDHQAHVVWRKDGVELGPSDKYDFLHTAGTRGLVVHSLTREDAGLYTCDVGTDE THAHVSVHELHVGITKRLKTVEVLEGESCSFECILSHEDSGDVAEWTVNGKTVVSSGRFC ATRQGRKYTLAIRDAVPSDAGEVVFSVRGLTSKASLIVKERSVDIMKPLEDQQATLGEDV VLRCELSREGTPVRWLKDGKAIRKSQKYDLLTEGTRASLVIHAATLKDSGKYTCETESSK STASLRVEEKANRFTEPLADLHVEEKGTATFICKTERPAVSVAWRKGLTELQASGKHTPS QEGLTLRLSISALEKADSGTYTCDIGQARSQAQLLVKGQKVLIIEDLEDAEVQEGSSATF CCRISPADYKPVHWFLDKTPLSANELNEIEAQPGGYHVLTLRQLALKDSGTVHFEAGDQR TSAALQVTEKPSVFSQGLTDATLMEGEDLTLVCETSVSDSPVCWTKDGKPLRPSARCRLT YEGRRAQLVITETTLQDSGRYKCEAAGAWSSSIVRVHARPVQFREGLKDVEVLEGGAATL RCVLSSVVRPVEWRRGDELLQPAGKYSLRQDGTVLELVVRDLRPQDSGQYFCSFGDQRTS ARLTVKALPAEFIGRLRSKEVTEGTTATFRCELSKEVPVEWKKGPETLRAGDRVSLRQDG AVCELEIRELTTEDAGEYSCVCGQEKTSATLTVRALPAEFTRRLRSKEATEGTTVMLHCE LSKAAPVEWRKGPETLRAGDRVSLRQEGAVCELEIRDLVVEDAGEYLCVCGQERTSATLT IRALPAKFTKGLKKEEAVEGATAILHCELSKAATVEWRKGPKTLRAGDRVSLRQEGAVCE LEIRELTVEDAGEYSCVCRQETTSATLAVRALPASFTKGLKKGEAVEGATVTLCCELGKT APVEWRKGPETLRAGDRVSLRQEGAVCELEIRDLTVEDAGEYSCVCGQERTSAMLTVKAL PTKFTNGLRKEEATEGTTVTLRCELSKVAPVEWRKGPETLRAGDRVSLRQEGAVCELEIR ELTVEDAGEYSCVCGQERTSATLAVRALPAKFTKGLKKEEAMEGATAILRCELSKVAPVE WRKGPETLRAGARVSLRQEGAVCELEIHELTVEDAGEYSCMCGQEKTSAALTVRALPAKF TKGLKKEEAVEGATAKLRCELSKAAPVEWRKGPETLRAGDRVSLRQEGAVCELEIRALTV EDAGEYSCMCGQEKTSATLAVRALPAKFTKGLKKEEAMEGATAKLRCELSKAAPVEWRKG PETLRARDRVSLRQDGAVCELEIRELTVEDAGEYSCMCGQEKTSAMLTVRALPAKFTKGL KKEEAVEGATAKLRCELSKAAPVEWRKGPETLRAGARVSLRQEGAVCELEICALTMEDAG EYSCMCGQEKTSAALAVRAMPARFIKELKTKEATEGATATLRCELSKAAPVEWRKGPEPV RAGDRVIQRQEGAVCELEIHELTVEDAGEYSCVCRQEKTSATLAVRALPAKFAKGLGKEE AMEGATAILCCELSKAAPVEWRKGPKTLRAGDRVSLRQEGAVCELEIRDLTVEDAGEYSC VCGQEKTSATLAVRALPAKFTKGLKKEEAVEGATAKLRCELSKVAPVEWRKGPETLRARD RVSLRQEGAVCELEIRGLTVEDAGEYSCVCGQERTSATLAVRALPAKFTKGLKKEEAMEG ATAILRCELSKVAPVEWRKGPETLRAGARVSLRQEGAVCELEIRELTVEDAGEYSCMCGQ EKTSAALAVRALPAKFTKGLKKEEAVEGATAKLRCELSKAAPVEWRKGPEILRAGDRLRV KQEGAVCELEIHDLTVEDAGEYSCMCEQEKTSATLSVRALPTKFTKGLKKEEAVEGATAI LRCELSKVAPVEWRKGPEILRAGDRLRVKQEGAVCELEIHDLTVEDAGEYSCMCGQEKTS AMLSVRALPAKFTRGLKKEEATEGATATLHCELSKVAPVEWRKGPETLRAGDRVRVKQEG AVCELEIRELTAEDAGEYSCMCGQEKTSATLAVRALPAKFLKGLRKEETTEGATAKLRCE LSKPAPVEWRKGPETLRAKDRVRVRQDGAVCELEIRELTAEDAGEYSCVCGQEKTSATLA VRALPAEFIGRLRSKEATEGATVTLCCELSKAAPVEWRKGSETLRAGDRVSLRQDGAMCE LEIRELVSTDAGDYSCVCGQERTSASLTVTAPQVVFRKPLQSLQAEEGTSASLRCELSEP GAAVVWSKGGLEVQADGRREPRQQGHVAELVLRGLRREDTGEYTCSCMSQATSATLSVTA APVRFLRELQAQEVDEGTTARLRCELSRAGSSVEWRKGSLQLFPCAKYQMVLEGTAAELL VHGAEQEDAGLYTCDTGHAQSTASLSVRAPRPVFKTELQSAEQEVGGVARLCCQLSDSEA GAPVLWLKEGVELHMSPKYEMQRQGATCELLIHGLEAKDMGEYSCMVGSQKTLAFLKVKE PEVTIVRGLVDTEVQADGEAEFSCEVSQAGVDVEWRLQGLPLQSNEVTEVAVQGGRTHTL RLKSVTPEDAGTVSFHAGRHTSSAQLTVRVPEVTILEPLQDAQLSEGQDAHFQCRLSRAL GQEAHWALGGVPLQANEMNDITVEHGTLHLLTLHKVTLEDAGTISFQVGSCRSEAQLKVT EAAPCLVRGLQNVDVFAGEVATFSCEVSRAGGPEAHWWLDGTLLQDGPQSAISVRDGTVH SLTLSGLGVADSGTITYRAGSLVSRAKLLVKDPTVEVVSAMRDLAVEEGGPAELLCQYSR PVQATWKMDEHAVCADGHRVIIEQDWTVARLSFRPALPCDSGIYSCEAAGTRVVALLQVQ AKNTVVRGLENVEAPEGGEALFECVLSQPEVAAHTWLLDDEPVRTSDNAEVVYFENGLRH LLLLKNLRPQDSCRVTFLAGDMVTSAFLTVRGWRLEVLEAPQDVTVHAGGQASFSCTLSE TVPVGEATWYLNGASVQPDDADWTVTADGSHHALLLHRAQPHHAGEVTFAARDAVASASL TVLGLPDPPEDAEVVGRSGSSVTLSWVAPTSDGGGGLRGYRVEMKAAASGEWQLCHGLVP GPECVVAGLAPGETYRFRVAAVGPAGAGEPVYLPQTVKLEEPLEPTPAAPAPESRQVAAG EDVCLECEVAEAGEVVWLKGTERVQPSGRFQLLRQGQRQMLLIRGFSTEDQGEYRCAPAR DSASGSAAAFQVVLTPESGEEVPAQPSLPPEAAQEGDLHLLWEALARKRRMSREPTLDSI SELPEEDGRPQGPRQEAEEAVPDLSEEYSTADELARTGEADLSHTSSDDESRAGTPSLVT YLKKAGRPSPSPLASKVGAPAAPSGKPQEKQQEKPPAVHPPPGDLSAGDLGDPTLDQAAV KIQAAFKGYKVRKKMQQQEGPVLRCTFGDTVAQVGDVLHLECVVSSKTDVRARWLKDGVE LTDSRHHHIDQLADGTCSLLVTSLGRADAGRYTCQVSNKFGHVAHSANVVVSGTESENES SSGGELDDTFRRAARRLHRLFRTKGPEEVSDEEIFFSADEGKAEPEEPGDWQTYREDEHS ICICFETLAEARRAASRFQEMFGVLGIRVDVSLSELGPRRVEMRIGKVAPAPSAPLEPVL AAEAAPVFLTELQNQEVLDGYPVSFDCVVTGQPVPTVRWFKDGRMLEEDDHYMISEDQQG GHQLIITAVVPADMGVYRCLAENSVGVSSTKAELRVDLTSTDYDTAADATETSSYFSAQG YLSSREQEGTESTSEEGQLPQVVEELKDLQVAPGTRLAKFQLKVKGYPTPRLYWFKDGQP LTASAHIRMADRKMLHTLEVVSVTTEDAGQYSAYISNTVGAAYSSARLLVRGPDEPEEKP ALDARQQLVPPRFLEKFTSKKVKKGSSITFSVKVEGSPPPAVHWLREEAEQGVLWISRHT PGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSAGLHVSGLPKEAGAMEEQP EVKEALISTFLQGTQAVAAQMSEPATFMDLAGQKKELLAAEARSHLSLAEVGTEEFLKKL TSQITEMVSAKITQAKLQVPGVDSDEESKTPSASPRHGRSRPSSSVQESSSESEDGDSRG EIFDIYVVTADYLPLGAEQDAILLREGQYVEVLDSAHPLRWLVRTKPTKNSPSRQGWVSP AYLDKRLKLSPEWGPAEAPEFPGEALSEDEYKTRLSAIIRDLLSSEQSFVGELQFLQSHH MQYLDRCPHVPAAVASQKAVIFRNVQDIGHFHSSFLQELRSCDTDDDVAMCFIKNQAAFE KYLEFLVGRVQAESVMVSTAVQEFYKKYTEEVLSAADPSQPPPPPLQHFLEQPVERVQQY QALLKELIRNKARNGQNCALLEQAYAVVSALPQRAENQLHVSLMENYPGTLEALGEPIRQ GHFIVWEGAPGARMPWKGHHRHVFLFRNHLVVCKPRRDSRTDTFSYVFRNMMKLSSIDLN DQVEGDDRAFEIWHEREDSVRKYLLQARTVITKNSWVKEICGIQQRLALPIWRPPDFEEE LADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCALILDNLTG ADSGQYMCFAASAAGNASTLGKILVQVPPRFVNKVRAVPFVDGEDAQITCTIEGAPYPQI RWYKDGALLTPGGKYQTLSEPRSGLLVLEIRAAGTEDLGIYECELVNRLGSKRSRAELLM QSPVLQAREQQRVERLAAVEDAAVPAPAAPGQESTSIQRTQTCPEAPGPSTGDHSSPSPS PGGPPALQEASPEPPSMEAGAASSEAWQQVEGEPPKAPQPVSHEGLEQTAQARTEVLERT VPIRMEGAAWPGAGELWDVHSHVFTETTHRTYVYQTSDTPAASPPSMQVTIEDVQAQSGG TAQFQAVIEGNPQPTVIWYKDGTQLGADPRLSQQQEGTTYSLVLRDVTQHDAGVYTCLAH NPGGQVLCKAELLIHGASPSLATRDSEHSSRRKLHSFYEVLEEIGRGVFGFVKRVQHKGN QMACAAKFIPLRSRTRAQAYRERDILAGLSHPLVTALLDQFETRKTLILILELCSSEELL DRLFKKSVVTEAEVKVYIQQLVEGLQYLHSQGILHLDIKPPNILMVHPAREDIKICDFGF AQKITPGEPQYSKYGSPEFVAPEIIEQTPVNEASDIWAMGVITYLSLTCSSPFAGESDRA TLLNVLEGRVSWSGPMATHLSEDAQDFIKAALQKAVGARPNAAKCLAHPWFRKSVPAEEA HFINTKQLKFLLARSRWQRSLMSYKSILVMRSIPELLQGPPDSPSLGIARHLRGDASASS SSSSSSDNELAPFARAKSLPSSPVTHSPLLHPRGFLRPSASLPEEAEACPPAAASALPAS LQGEEPAAALGCVPRQSVIRSLFYQQVGEGPELGGPSPGGRRHPARRRHLLKGGYFSGVL PGLREPLLEHRALEEAAAMEEQAARQATAASLETAVQMPRASTQEASVSSRSLDRDPPNT ASSSTKACSKGQCPAPAPLSPQDAQGEGTPGGGARAREKEHPEGTPRGLTRPSASSDGCS IQPQESSQDRCGGQAAPFSQPQWVPAPQDRAPPAALAPQPSGSFPSGPCTEALSSSPSPS FPGKPQACLPPAQASPQVDSQSGLKAVPLTKRPGSPRPPEPASQMGTEPSPSLDTEGLVQ ETEDLSPSSPSLQRPQEQATTRKFSLGCRGGYAGVAGYGTFAFGGDAGGMLGQGPMWAKM TWAVSQSSEEQDEAGTESPLPQASTAPAPEGDGTLPRASQELSSWEDFTGGSQVSLIQIQ DLSRDPEAADTVSLDISEVDPAYLNLSDLYDIKYLPFEFMIFRKIPKPVEPERPSSPESE AGEELAELPEAAWPWPASLEITEEPEDMEALLGKAAGGRKRKWSPPSGSLFHFPGRRSLL EEPTELGLRQRVKASVAHISRLLRGRPEGLEKESPPRKKAGLASFRLKSKDRAPSFLREL SDETVVLGQSVTLACQVVAQPAAQATWSKDGALLESSSRLLISSTLKNFQLLTILVVTAE DLGVYMCSVSNALGTAATTAILRKAERPSSSPRPDIGEVHADGVLLVWKPVESYGPVTYI VQCSLEGGSWSTLASDVFDCCYLTGKLSRGGAYTFRTACVSKAGMGPYSSPSEQVLLGGP SRLASEEESGAAGPAQPLPSMQTFAFQTQMRRGRFSVVRQCQEKASGRVLAAKIVPYHAA DRAAVLREYEALKGLRHPHLAQLQAAYLSPRHLVLILELCSGPELLPCLAERASYSESEV KDYLWQILSATQYLHAQGILHLDLRSENMIVTEYNLLKVIDFGNAQSLAQERVLPSERFK DYMETMAPELLEGQGAVAQTDIWAIGVTAFIMLSAEYPVSGEGTRDTQKGLRKGLIQLSR CYAGLSGGAVAFLRSTLCVHPWVRPCASSCLQSPWLTEEGPASSQPAAVTFPTTGLRVFV REREKRRALLYKKHNLR NT seq 28854 nt NT seq  +upstreamnt  +downstreamnt atggatcactcctcgttcagcggtgcaccccgcttcctaacccggcccaaggccttcgtg gtatcggtgggcaaagatgccacgctgagctgccagatcgtgggcaaccccacgccgcaa gtgagctgggagaaagaccggcagctggtggaggcgggtgggcgcttccgcctggcccag gacggcgacctgtaccgcctgaccatcctggacctggcgctgggcgacagtgggcagtac gtgtgccgtgcgcgcaacgccatcggtgaggccttcgcggcggtcggcctgcaggtggac gccgacgccgcctgcgccgagcaggcgcctcacttcctgctgcggcccacctccatccgg gtgcgcgagggcgccgaggccaccttccgctgccgcgtgcgcggttcgccgcccatgtcg gtgagctgggccaaggacggccggcgcctgggtgcgttggacgccccccgagtgcgagtg gaagagagcggcgaggcgagtgctctgcgcatccgggctgcacagccgagagacagcggc acctatacggtgcacgcagagaacccgctgggcgccgccagcgccgccgccgggcttacg gtggacgcggaggcggaggcagccaacccaccgggggcctccaccgccatgctcctggcg cacctgcagcggcggcgcgaggccatgcgcgccgggggcgccccggcctcgccgccgagc gccggcacgcgcacctgcacggtgacagagggcaaacacgcgcgtctcagctgcttcgtg acgggcgagcccaagcctgagatcgtgtggaagaaggatggacagctggtggtggagggc cggcggcacgtggtgtatgaggacgagcaggagaacttcgtgctgaagatcctcttctgc aagcagtcagactgtggcctctacacctgcacggcgtccaaccttgtgggccagacctac agctcggtgctggtcgtcgtgagagagcccacagtgcccttcagaaagcgcctgcaggac ctggaggtgccggagaaggcatcagccacgttccagtgtgaagtaccggtgccagccatg gagtctgcctggtataaggaggaaacgcgactgtgggccagcgagaagtacctcatcgag gaggcgggcgctgagcgccggctgacagtgctcaacgtctcttccgatgacgacgccgtg tacatctgtgagacggcagagggcagtcgcacggtggctgagctggcagtgcgaggcaac ctccttcggaagctcccgaggaagacagctgtacgagtgggagacaccgccatgttctgt gtggagctggccaagcccgagggccccgttcagtggctgtggaaccggaaggcggtggtg gctgggggccgggtggccatcactgcggagggcacttgccacacgctgaccatctcccag tgcagcctggaggatgtgggtgaggtggcctttgtggctggggactgccggacgtctacc cagttttgtgtgtcagcccccaggaggccgcccctgcatgctcctgaagcccctgtggtg aaggcccagacagagagctccgtgactcttggctggtccccgccacccgctggggaccgc cctgctgccatcgagggctacctggtggagaagaagaggctgggcgcctacacctggagc cggtgccatgaagatgagtgggtgaccacgcctgagctgactgtggctggtgtggctgag gagggggagttccagttcagggtgtcagctgtgaacagctttggccagagcccctacctc gagttcccaggaactgtacatctggctccccagctggctgtgaaaacacctctgaaggca gtggaggcagtggaaggcggcgaggtgaccttctctgtggacctcactacggcctcatca ggggagtggttcctggacgggcgggtcctgaaggccagcagcgtgtatgtgatacggcgg gatggcacccgccacactctcaccatccgctcggtgcctgtcagcctgcacggggcggag ctcaagttcgtggccaatggcatcgagagcagcatccgcatggaggtccgagcgcccctg gagctgacggccaagtgtccggcaccagcagcagccgctcgggaggtgctggcccggctg cacgaggaggcccagctcctggctgagctgtcggaccaggcggcagccgtgacgtggctc aaggatggacacacgctgtctcccggccccaagtatgaggtgcaggcttcagctgggcag cgggcactgctcgtgcgggacgtgaagcgagaagacgcgggcctgtatgagtgcgtcagc cgcgggggccgcgtcgcctaccagctgctggtgcaagagtcttctgcagtgtttatcaag gggcagccaatgcataaggaggtaaaggccgtggcgggggcgagtgccacactgagctgc gaggtggcccaggcccagacggaggtgacgtggtacaaggatgggaagaagctgagttcg agctcgaaagtgcatgtggaggccaagggctgcacccggcagctggtggtgcagcaggcg ggcaaggcggacgccggggagtacagctgcgaggctgggggccagaaggtctccttccac ctggacgtcgcagagcccttggtggtgtttgccaaggagcagccagcacgcagtgaagtg caggccgtggcaggaaccagtgccacgctgagctgcgaggtggcccaggcccagacggag gtgacgtggtacaaggacgggaagaagctgagttccagctcgaaagtgcgtgtggaagcc aagggctgcaccaggcggctggtggtgcagcaggcgggcaaggcggacgctggggagtac agctgcgaggccgggggccagaaggtctccttccacctggacgtcacagagccctcggtg gtgttcgccaaggagcagccggcacgcagtgaagtgcaggctgtggcgggggcgagtgcc acgctgagctgcgaggtggcccaggcccagacggaggtgacgtggtacaaggatggcaag aagctgagttccagctcgaaagtgcgtgtggaggccacgggccgcgggcggtggctggtg gtgcagcaggcgggcaaggcggacgccggggagtacagctgtgaggccgggggccagaaa gtctccttccacctggacgtcacagagccctcggtggtgtttgccaaggagcagccagca cgcagtgaagtgcaggccgtggcgggaaccagtgccacgctgagctgtgaggtggcccag gcccagacggaggtgacgtggtacaaggatgggaagaagctgagttccagctcgaaagtg cgtgtggaggccaagggctgcacccggaagctggtggtgcagcaggcgggcaaggcggac gccggggagtacagctgcgaggccgggggccagaaggtctccttccgcctggacgtcaca gagccctcggtggtgttcgccaaggagcagccggcacacagtgaagtgcaggccatggca ggggcgagtgccacgctgagctgcgaggtggcccaggcccagacggaggtgacgtggtac aaggatgggaagaagctgagttccagctcgaaagtgcgtgtggaggccacgggccacggg cggcggctggtggtgcagcaggcgggcaaggcggacgccggggagtacagctgcgaggcc gggggccagaaggtctccttccgcctggacgtcacagagccctcggtggtgtttgccaag gagcagccagcacgcagtgaagtgcaggccatggcgggaaccagtgccacgctgaactgc gaggtggcccaggcccagacggaggtgatgtggtacaaagacggaaagaagctgagttcg agctcaaaaatgcgtttggaagccaagggctgcacccggcagctggtggtgcagcaggcg ggcaaggcggacgcaggggagtacagctgcgaggccgggggccagaaggtctccttccgc ctggacgtcacagaaccctcggtggtgtttgccaaggagcagccggcacgcactgaagtg caggccgtggcggggacgagtgccacgctgagctgcgaggtggcccaggcccagacggag gtgacgtggtacaaggagggcaagaagctgagttccagctcgaaagtacatgtggaagcc aagggctgcaccaggcggctggtggtgcagcaggcaggcaaggtggacgccggggagtac agctgcgaggccgggggccagaaggtctccttccacctggacgtcacagagccctcggtg gtgttcgccaaggagcagccggcacgcagtgaagtgcaggccgtggcaggggcgagtgcc acgctgagctgcgaggtggcccaggcccagacggaggtgacgtggtacaaggacggcaag aaactgagttccagctcgaaagtgcgtgtggaggccacaggccgcgggaggcggctggtg gtgcagcaggcgggcaaggcggacgccggggagtacagctgcgaggccgggggccagaag gtctccttccgcctggacgtcacagagccctcggtggtatttgccaaggagcagccggca tgcagtgaagtgcaggccgtggcaggggcaagtgccacgctgagctgcgaggtggcccag gcccagacagaggtgacgtggtacaaggacggcaagaagctgagttcgagctcaaaagtg cgtgtggaggccacgggccgcaagcggcagctggtggtgcagcaggcggacaaggcggat gctggggagtacagctgcgaggctgggggccagaaggtctccttccgcctggatgtcaca gagccctcggtggtgttcgccaaggagcagccggcatgcagtgaagtgcaggccatggcg ggggcgagtgccacgctgagctgcgaggtggcccaggcccagacggaggtgacgtggtac aaggacgggaagaagctgagttcgagctcgaaagtgcgtgtggaggccacgggccacggg cggcggctggtggtgcagcaggcgggcaaggcggacgccggggagtacagctgcgaggcc gggggccagaaggtctccttccacctggacgtcacagagccctcggtggtgtttgccaag gagcagcccgcacgcagtgaagtgcaggccatggcgggagcgagtgccacgctgagctgc gaggtggcccaggcccagacggaggtgacgtggtacaaggacgggaagaagctgagttcc agctcgaaagtgcgtgtggaggccaagggctgcacccggaagctggtggtgcagcaggcg ggcaaggtggacgctggggagtacagctgcgaggctgggggccagaaggtctccttccac ctggacgtcacagagccctcggtggtgttcgccaaggagcagccggcacgcagtgaagtg caggccgtggcaggggcgagtgccacgctgagctgcgaggtggcccaggcccagacggag gtgacgtggtacaaggacggcaagaagctgagttccagctcgaaagtgcgtgtggaggcc acgggccgcggacggcggctggtggtgcagcaggcgggcaaggcggacgccggggagtac agctgcgaggccgggggccagaaggtctccttccgcctggacgtcacagagccctcagtg gtgttcgccaaggagcagctggcacgcagtgaagtgcaggcaatggcgggggcgagtgcc acgctgagctgcgaggtggcccaggcccagacggaggtgacgtggtacaaggacggcaag aagctgagttcaagctcgaaagtgcgtgtggaagccaagggctgcaccaggaggctggtg gtgcagcaggcgggcaaggcggatgccggggagtacagctgcgaggccgggggccagaag gtctctttccacctggatgtcacagagcccttggtggtgttcgccaaggagcagccggca cgcagtgaagtgcaggccgtggcgggggcgagtgccacgctgagctgcgaggtggcccag gccctgacggaggtgacgtggtacaaggacggcaagaaactgagttccagctcgaaagtg cgtgtggaagccaagggctgcacccggaagctggtggtgcagcaggcgggcaaggcggac gccggggagtacagctgcgaggccgggggccagaaggtctccttccacctggacgtcgca gagcctgtggtggtgtttgccaaggagcagccggcacgcagtgaagtgcaggccaaggca ggagcccgcaccacactgagctgcgaggtggcccaggcccagacggaggtgacgtggtac aaggatgggaagaagctgagttcgagctcaaaagtgcatgtggaggccaagggctgtacc cggcagctggtggtgcagcaggcgggcaaggcagacgccggggagtacagctgcgaggcc aggggccagaaggtctccttccacctggatgtcacagagccggagtttgagcctccggcc ccagagaaacccagacgcagggaaccgctggtggtcagggaacacgaggacatcgtcctg acagccactctggccacgccgtctgtggccacggtgacgtggttcaaagatggtgtggag attcgccgcagcaagcggcatgagatgaccagcctaggggacacccacaccctgaccatg catggggcacagaccctggacagcgctgtctacagctgccgcgtgggcgcagaggggcag gacttcccggtgcaggtggaagaggtggctgccaagttttgccgccccctggagcccgtg agcggggatctgggcggcacggcgacgctggtctgtgagctgagccctgcgcaggctgag gtggtgtggcgccgcggaagcacgcaactccggtccggcaaacgcttccagatggcggct gcggggcctcggcgctcgctcacggtgtcgggcctgcgggcagaggatgcaggggagtac gtgtgtgagagccgcgacgaccacaccagcgccatgctcactgttatcgtaccccgcgtg gtcaagttcacgtctgggctgagtgcggtggttgcggaggaggggagcgaggccactttc cagtgcgtggtgacccccagcgacgtggcggtcacatggttccgagatggtgtccaacta cagtccagtgagaagtttctcatatcgcagaagggtgccagccacagcctgaccatctta agcctggccctggaggatgccggccaggtcactgcggaggctgagggcatccagtccacg gctgccctccgggtccgagaggctccagtgttgttcagaaagaagctggagccacagacc gtggaggagcggagctcagtgaccatggaggtggagctgactcggccgtggccggaggtc aagtggacacgcaatgctgtagcacttgcgtcgggcgagaaagtggagatccacgccgag ggcgctcgtcaccgcctggttctccacggtgtgggtttcgctgaccgtggcttctacggc tgcgagacaccagacgacaagacgcaggccaagctgactgtggaaatgcgccaggtccgg ctcgtgcggggcctgcaggccgtggaggcgcaggagcagggcacggccactatggaagta gagctgtcccacgctgacgtggagggcaactggactcgagacggtcttcggctccagcca ggacccaactgccagctggcggtgcacggcgccacacacaccctcacgctgtcacggctg cagcggcaggacggcggcttggtggccttcagggcggagggcgtgcacacctctgctcat ctggtggtcactgagctgcctgtgaagttcgtccgccctctgcaggacgtggtggccaca gagaaggaaaaggtggccctggactgtgagctctcacgccccaatgtggatgtgcgctgg ttgaaggacaatgtggagctgcgggtaagcaagaccatgggcatgatggcccagggggcc tgcaggagtctcatcatttaccgatgtgagcttggagaccagggcgtgtacgtgtgcgat gcccacgatgctcagagctcggcctccctgaaggtgcaaggccggaatgtgcagatcgtg aggcctctggacgatgtggaagtggtggagaaagagggcgccaccttctcctgcaaggtc tcccacgatgaggtgcctgcacagtggttctgggagggcagtaagctccggcccagtgac aacgtgaggatccgccaggaaggaaggacatacactctcatctatcggagggtcctggtg gaagatgcaggggaaatcaagtttgtagcggaaaatgcagaatcgcgagcccagctccga gtaaaagagctgcccgtgtccatcctccgcccgctgcgggataagatcgccatggagaag caccgcggtgtgctcgagtgccagatgtccagggccagtgcccaggtgcggtggttcaag ggtagcgtggagctccatcccggagccaagtacgagatggtcagtgacggcctctaccgc aagctggtcatcaacgccgtccagcccgaggacgaggacacctacacgtgtgatgccggc gacgtgaagaccagtgcccagttctttgtagaagagcagtccatcgtggtcgtgcggggc ctgcaggatgtgacggtgatggagccggcgcctgcctggttcgagtgtgagacctccatc ccctcggtgcgacccgccaagtggctcctgggaaagacggtgctgcaggcggggcctgac gtggggatagagcaggagggcacggtgcatcggctgacgctgcggcgcacctactccacc atgacggggccagtgcacttcaccatcggcaagtcgcgctccaccgcctccctggtggtc tctgacattcccgtggtgctcacacggcccctggagcccaaggtggggcgggagatgcag tccgtcgtcctgtcctgtgacttcaagcctccccccaaggctgtgcaatggtacaaggag gaaacgcccctggcgccatccagcaagttcaagatgaggctggagggccacatggcagag ctgcgtgtcctgcggctcacccctgacgatgctggtgtttaccggtgccaggctggcagc gcccagagcagcgcggaggtcactgtggaagaacggaaggtgacggtgacgcagccgctg gaggacgtggaggtcccggaggagggccgtgcctgcttctcctgcgagctgtcccacgag gacgaagaagtggactggttgctcaacgggacaccgctctttaacgacagcttccatgag atcacccacgagggccgccgccacacactggtgctgaagcgggtccggcaggccgacagg ggcaccgtgagcatctcctcccccaaggttgcggcctccgcccacctggcggtcagaggg aagccggtggtgttcctgaaggcgttggacgatgtgtctgcagaggagcggggcagactg accttgcagtgcgaggtttctgaccaccaagcccacgtggtgtggcggaaggacggtgtg gagttgggccccagcgacaagtatgacttcctgcacacggcgggcacacgaggcctcgtg gtgcacagcctgactcgggaggatgctggcctgtacacctgcgatgtgggcactgatgag acccatgcccatgtcagcgtgcatgagctgcacgtcggtatcaccaagaggctgaagaca gtggaggtgctggagggcgagagctgcagcttcgagtgcatcctgtcccatgaggacagt ggcgacgtggctgagtggacagtgaacgggaaaacagtggtcagctctggccgcttctgt gccacgcgccagggccgcaagtacaccctagctatccgagatgccgtgccaagtgacgct ggggaggtggtcttctctgtgcggggcctcacctccaaggcctcgctcattgtcaaagag aggtcagttgacattatgaagccactggaagaccagcaggccacgctgggtgaggatgtg gtgctgaggtgtgagctgtcgcgggaggggaccccggtgcgctggctgaaggatgggaag gccatccgcaagagtcagaagtatgacctgctcactgaaggcactcgggcctcgctggtc atccatgcagccacactcaaagactcgggcaaatatacatgtgagacagagtcttccaaa agcacagccagtctccgagtggaagaaaaggcaaaccggttcacggagccgttggctgac ctgcacgtggaggagaagggcacagccacgttcatctgcaagacggagcgccccgcggtc tcagtggcctggcgcaagggcctcacggagctgcaggcctcggggaagcacacgcccagc caggagggcctgaccttgcggctcagcatcagcgccctggagaaggcagacagtggcacg tacacctgcgacatcggccaggcccggtcccaggcgcagctcctggtgaaaggccagaaa gtgctcatcatagaggacttggaggacgcggaggtgcaggagggctcctcggccaccttc tgctgccgtatctcccctgccgactacaagcctgtccactggttcttggacaaaacgccc ctgtctgccaatgaactcaatgagattgaggcccagcccggcgggtaccacgtgctgacc ctgcggcagctggcactcaaggactcgggcaccgtccattttgaggcaggtgaccagcga acctcagctgccctgcaggtcacagagaagccaagtgttttctcccaggggctcacggat gccacactcatggagggggaggatctgaccctggtctgtgagacttccgtctcagacagc cctgtgtgctggaccaaggatgggaagcccctgcggccatcggcccggtgccggctgacc tatgagggccgccgggcccagctggtcatcactgagaccaccctgcaggacagcgggcgc tacaagtgtgaggctgcgggcgcctggagcagctccattgtcagggtccacgctcggcca gtgcagttccgagagggcctgaaagacgtggaggtgctggaagggggtgctgccacgctg cgctgcgtgctgtcctccgtggtcaggcctgtggagtggcggcgtggggatgagctcctg cagcctgcaggcaagtacagcttgcggcaggatgggaccgtgctggagctggtggtccga gacctgcgacctcaggacagcgggcagtacttctgcagtttcggggaccagaggacgtcg gccaggctcaccgtaaaggctctgcctgctgagttcataggaagactgagaagcaaggag gtcacggaagggaccacagccacattccgctgtgagctcagcaaggaagtccccgtagag tggaagaaggggcccgaaaccctcagagccggggacagagtaagcctgaggcaggacggg gccgtgtgtgagctggagatccgtgagctgaccacggaggatgctggagaatattcatgt gtgtgtgggcaggagaagacctcagccacgctcaccgtcagggctttgcctgctgagttc acaagaagactgagaagcaaggaggccacagaagggaccacagtcatgctgcactgtgag ctgagcaaggcggcccccgtggagtggaggaaggggcccgagaccctcagagccggggac agagtgagcctgaggcaggagggagccgtgtgtgagctggagatccgtgaccttgttgtg gaggatgctggggagtatttgtgtgtgtgcgggcaggagaggacctcagccacactcacc attagggccctgcctgccaagttcacaaagggtctgaagaaggaagaggccgttgaaggg gccacagccatactgcactgtgagctgagcaaggcggccactgtggagtggaggaagggg cccaagaccctcagagccggggacagagtgagcctgaggcaggagggagccgtgtgtgag ctggagatccgtgagctgaccgtggaggatgctggagaatattcatgtgtgtgcaggcag gagacgacctcagccacactcgctgtcagggccctgcctgccagcttcacaaaaggtctg aagaagggagaggccgtggaaggggccacagtcacgctgtgctgtgagctgggcaagacg gcccccgtggagtggcggaaggggcccgagaccctcagagccggggacagagtgagcctg aggcaggagggagccgtgtgtgagctggagatccgtgacctgaccgtggaggatgctggg gagtactcctgcgtgtgcgggcaggagaggacctcagccatgctcaccgtcaaggccctg cccaccaagttcacaaacggcctgaggaaggaggaggccacagaagggaccacggtcacg ctgcgctgtgagctgagcaaggtggcccctgtggagtggaggaaggggcccgagaccctc agagccggggacagagtgagcctgaggcaggagggagccgtgtgtgagctggagatccgt gagctgaccgtggaggatgctggggagtactcctgcgtgtgcgggcaggagaggacctca gccacgctcgccgtcagggccctgcctgccaagttcacaaaaggtctgaagaaggaagag gccatggaaggggccacagccatactgcgctgtgagctgagcaaggtggcccccgtggag tggaggaaggggcccgagaccctcagagccggggccagagtgagcctgaggcaggaggga gccgtgtgtgagctggagatccatgagctgaccgtggaggatgctggggagtactcgtgc atgtgtgggcaggagaagacctcagctgctctcaccgtcagggccctgcctgccaagttc acaaaaggtttgaagaaggaagaggccgtggaaggggccacagccaagctgcgctgtgag ctgagcaaggcggcccccgtggagtggcggaaggggcccgagaccctcagagccggggac agagtgagcctgaggcaggagggagccgtgtgtgagctggagatccgtgccctgaccgtg gaggatgctggggagtactcgtgcatgtgcgggcaggagaagacctcagccacgctcgcc gtcagggccctgcctgccaagttcacaaaaggtctgaagaaggaagaggccatggaaggg gccacagccaagctgcgctgtgagctgagcaaggcggcccctgtggagtggaggaagggg cccgagaccctgagagccagggacagagtgagcctgaggcaggatggggccgtgtgtgag ctggagatccgtgagctgaccgtggaggatgctggggagtactcgtgcatgtgcggacag gagaagacctcagccatgctcaccgtcagggccctgcctgccaagttcacaaaaggtttg aagaaggaagaggccgtggaaggggccacagccaagctgcgctgtgagctgagcaaggcg gcccccgtggagtggaggaaggggcccgagaccctcagagccggggccagagtgagcctg aggcaggagggagccgtgtgtgagctggagatctgtgccctgaccatggaggatgctggg gagtactcatgcatgtgcggacaggagaagacctcagccgcgctcgccgtcagggccatg cctgctcggttcatcaaagaactgaagaccaaggaggccacagaaggggccacagccaca ctgcgctgtgagctgagcaaggcggcccccgtggagtggaggaagggacctgagcccgtc agagccggggacagagtgatccagaggcaggagggagccgtgtgtgagctggagatccat gagctgaccgtggaggatgctggggagtactcgtgtgtgtgcaggcaggagaaaacctca gccacgctcgccgtcagggccctgcctgccaagtttgcaaaaggtttgggaaaggaagag gccatggaaggggccacagccatactgtgctgtgagctgagcaaagcggcccccgtggag tggaggaaggggcccaagaccctcagagctggagacagagtgagcctgaggcaggaggga gccgtgtgtgagctggagatccgtgacctgactgtggaggatgctggagaatattcatgt gtgtgcgggcaggagaagacctcagccacgctcgccgtcagggccctgcctgccaagttc acaaaaggtctgaagaaggaagaggctgtggaaggggccacagccaagctgcgctgtgag ctgagcaaggtggcccctgtggagtggaggaaggggcccgagaccctgagagccagggac agagtgagcctgaggcaggagggagccgtgtgtgagctggagatccgtggcctgaccgtg gaggatgctggggagtactcctgcgtgtgcgggcaggagaggacctcagccacgctcgcc gtcagggccctgcctgccaagttcacaaaaggtctgaagaaggaagaggccatggaaggg gccacagccatactgcgctgtgagctgagcaaggtggccccagtggaatggaggaagggg cccgagaccctcagagccggggccagagtgagcctgaggcaggagggagccgtgtgtgag ctggagatccgtgagctgactgtggaggatgctggggagtactcgtgcatgtgcgggcag gagaagacctcagccgcgctcgccgtcagggccctgcctgccaagttcacaaaaggtttg aagaaggaagaggccgtggaaggggccacagccaagctgcgctgtgagctgagcaaggcg gcccccgtggagtggaggaaggggcccgagatcctcagagctggggacagactgcgggtg aagcaggagggagccgtgtgtgagctggagatccatgacctgaccgtggaggatgctggg gagtactcgtgcatgtgcgagcaggagaaaacctcagccacgctctctgtcagggctctt cccaccaagttcacaaagggtctgaagaaggaagaggccgtggaaggggccacagccata ctgcgctgtgagctgagcaaggtggcccccgtggagtggaggaaggggcccgagatcctc agagctggggacagactgcgggtgaagcaggagggagccgtgtgtgagctggagatccat gacctgaccgtggaggatgctggggagtactcatgcatgtgcgggcaggagaagacctca gccatgctctctgtcagggccctgcctgccaagttcacaagaggtctgaagaaggaagag gccactgaaggggccacagccacactgcactgtgagctgagcaaggtggcccccgtggag tggaggaaggggcccgagaccctcagagccggggacagagtgcgggtgaagcaggaggga gccgtgtgtgagctggagatccgtgagctgaccgcggaggatgctggggagtactcgtgc atgtgtgggcaggagaagacctcagccacgctcgccgtcagggccctgcctgccaagttc ctgaagggtctcaggaaggaggagaccacggaaggggccacagccaagctgcgctgtgag ctgagcaaaccggcccccgtggagtggaggaaagggcccgagaccctcagagccaaggac agagtgcgggtgaggcaggacggggccgtgtgtgagctggagatccgtgagctgaccgcc gaggatgctggagaatattcatgtgtgtgtgggcaggagaagacctcagccacactcgcc gtcagggctttgcctgctgagttcataggaagactgagaagcaaggaggccacggaaggg gccacagtcacgctgtgctgtgagctgagcaaggcggcccccgtggagtggaggaaggga tctgagaccctcagagccggggacagagtgagcctgaggcaggacggggccatgtgtgag ctggagatccgtgagctggtttcgacagatgctggggactactcatgtgtgtgcgggcag gagaggacctcagcctcgctgacggtcacggccccacaggtggtgttccggaagccgctg cagagcctgcaggctgaggagggtacctcggccagcctgcggtgtgagctttccgagcct ggagccgccgtcgtctggagtaaggggggcctggaggtgcaggccgatgggcgccgggag ccgcggcagcagggccacgtggcagagctggtgctgaggggcctgcgccgggaggacacg ggagagtacacctgcagctgcatgtcccaggccactagcgccaccctgtccgtcacagct gcgcctgtgaggttccttcgagagctgcaggcccaggaggtagacgagggcacgacggca cgcctgcgctgtgagctgagccgggcgggcagcagtgtggagtggcgcaagggctccctg cagctcttcccgtgtgccaagtaccagatggtgctggaaggcacagccgctgagctgctg gtgcacggggccgagcaggaggatgctggcctctatacctgtgacacgggccacgcacag agcaccgccagcctctctgtccgggcccccaggcctgtgtttaagacggagctgcagagt gctgagcaggaggtgggcggcgtggcccggctgtgctgccagctgagtgattccgaggct ggggcccccgtgctgtggctcaaggagggtgtggagctgcacatgagtcccaagtatgag atgcagcgccagggagccacgtgtgagctgctgatccatgggcttgaggccaaggacatg ggcgagtacagctgcatggtgggcagccagaagaccttggccttcctcaaagtcaaagag cctgaggtgaccatcgtgcggggcctggttgacaccgaggtccaggctgatggggaagca gagttcagctgcgaggtgtcacaggctggcgtggacgtggagtggcgcctgcagggcctg ccgctgcagagcaacgaggtgaccgaagtagcggtgcagggtggccgcacccacacactg aggctgaagagcgtgaccccagaggacgccggcactgtctccttccacgcgggccgccac acgtcctctgcccaactcaccgtccgagttcctgaggtgaccatcctggagcccctgcag gacgctcagctcagcgagggccaggatgcccacttccagtgccgactgtcgagggctttg ggccaggaggcccactgggccctgggaggcgtgcccctgcaggccaacgagatgaacgac atcacggtggagcatggcacactccacttgctcaccctgcacaaggtcaccctagaggac gctggaaccatcagtttccaagtgggctcatgtcgctcggaggcccagctgaaggtcaca gaggcagcaccgtgcctggtacgtggcttacagaatgtggacgtctttgcgggggaggtg gccacgttctcctgcgaggtgtcccgtgctggtgggccggaggcccactggtggctggat gggaccctgctgcaggacggcccccagagtgccatctccgtgcgtgatgggaccgtccac tccctcacgctctcaggcctgggggtggctgactcaggcaccatcacctaccgagcaggg tccctggtctccagggccaagttgttggtcaaagatcccacagtggaagtggtcagtgcc atgcgggacctggcagtggaggagggtggcccggccgagctcctctgccagtactcacgg cccgtgcaggccacgtggaagatggacgagcatgcggtgtgtgcggacgggcaccgtgtc atcatagagcaggactggaccgtggccaggctgtctttcaggccggccttgccctgtgac agcggcatctattcttgcgaggccgcgggcacccgcgtggtggccctgctgcaagtgcaa gccaagaacacggtggtgaggggcctggaaaacgtggaggcgcccgagggcggcgaggcg ctgttcgagtgcgtcctgtcccagccggaggtggccgcccacacctggctgctggacgat gagcccgtgcgcacctctgacaatgccgaggtggtctacttcgagaacggcctgcggcac ctcctgctgctcaaaaacctgcggccacaggacagctgccgtgtgaccttcctggcaggg gacatggtgacgtctgccttcctcaccgtcagaggctggcgtctggaggtcttggaggcg ccccaggatgtgaccgtgcacgctggggggcaggccagcttcagctgcacccttagtgag acggtgcccgtgggcgaggcgacctggtacctaaatggagcctccgtgcagcccgatgac gcggactggaccgtcaccgccgacggcagccaccacgccctgctgctgcaccgggcccag ccgcaccacgccggcgaggtcacctttgctgctcgcgatgctgttgcctccgcgagtctc actgtgctgggcctccccgaccccccagaggacgcagaggtggtggggcgcagcggcagc tccgtgacgttgtcctgggtggcccccacgagcgatggcggagggggtctccgtggctac cgggtagagatgaaggcagcagcctcgggagagtggcagctgtgccacggtctggtgccc gggcccgagtgtgtggtggctggcctggcccccggggagacctaccgcttccgcgtggct gcagtgggcccggcgggcgctggggagcccgtgtacctgccccagacggtgaagctcgaa gagcccctggagcccacgcctgcggcccccgcccccgagagccggcaggtggcggccggg gaggacgtgtgtctggagtgcgaggtggccgaggcgggtgaggtcgtctggctgaagggg acggagcgcgtccagccgagcgggcgcttccagctgctccgccagggccagcggcagatg ctgctgatccggggcttctccacggaggaccagggcgagtaccgctgtgcccctgcacgg gactcagcctctgggtcagctgctgctttccaggtggtgctgaccccagaatccggggag gaggtccctgctcagcccagcctgccccctgaggcagcccaggagggcgacctgcacctg ctgtgggaggcgctggcccggaagcgccgcatgagccgcgagcccacgctggactccatc agcgagctgcccgaggaggacggccgcccgcagggcccgcggcaggaggccgaggaggct gtgcctgacctctcagaggagtactccacggctgacgagctggcgcgcacgggcgaggcc gacctctcgcacaccagctctgacgacgagtcccgtgcaggcaccccttcgctggttacc tacctcaagaaggctgggaggcccagcccctcgccactggccagcaaggttggggcccca gcagccccctctgggaagccacaggagaagcagcaggagaagccacctgcagtacaccca ccaccaggagacctgagcgctggggacctgggtgacccgaccttggatcaggccgcagtg aagatccaggcggccttcaagggttataaggtccggaagaagatgcagcagcaggagggg cccgtgctccgctgcacgtttggggacaccgtggcacaggtgggagacgtcctgcatctg gagtgtgtcgtgtccagcaagacagatgtgcgcgcccgctggctgaaggatggtgtggaa ctgacggacagccggcaccaccacattgaccagcttgcggacggcacctgttctctgctg gtcactagcctggggcgggccgacgctggccgttacacctgtcaggtgagcaacaagttt ggccacgtggcccacagtgccaacgtggtggtcagtggcacggagagtgagaacgagagc tcctccgggggtgagctggatgacaccttccgccgggccgcccggcggctgcaccgcctc ttccgcaccaaaggcccagaggaggtctcggacgaggagatcttcttcagcgctgacgag ggcaaggcagagcctgaggagcctggggactggcagacgtaccgcgaagatgagcactcc atctgcatctgctttgagacgctggcagaggcccgccgggcagccagccgcttccaggaa atgtttggcgtgttgggcatccgtgtggacgtcagcctgtccgagctgggaccacgcagg gtggagatgcgcattggcaaggtggcacccgccccttcagccccgctggagccagtgctc gcggcagaggctgccccggtgttcctgaccgagctacagaatcaggaggtgctggatggg taccctgtgagctttgactgtgtggtgacaggccagcctgtgcccactgtgcggtggttc aaggatgggaggatgctggaggaggatgaccactacatgatcagtgaggaccaacagggt ggccaccagctcatcatcacggctgtggtgccggcagacatgggtgtctaccgctgcctg gccgagaacagcgtgggtgtgtcctctacaaaggcagagctccgtgtggacctgaccagc accgactatgacacagctgcggacgccacagagacctcgtcctacttcagcgcccagggc tacctgtccagccgggaacaagagggtacagagtctacctcggaggaggggcagctgccc caggtggtggaggagctgaaagacctgcaggtggcccccggcacacggctggccaagttc cagctcaaggtgaaaggctaccccacacctcgactctactggttcaaagacgggcagccc ctgaccgcatctgcgcacatacgtatggcggacaggaagatgctccacaccctggaggtt gtctctgtcaccaccgaggatgcagggcagtactcggcctacatcagcaacaccgtgggt gctgcttactcctctgctcggctcctggtccgaggccctgatgaaccagaagagaagcca gcattagatgcacgccagcagctggtcccaccccggttcctggagaaattcacctccaag aaggtgaaaaaaggttccagcatcactttctctgtgaaggtggaagggagcccgccgccg gctgtgcactggctgcgagaggaagcggagcagggtgtgctgtggatcagccgccacacg ccaggctacacagtggccagctctgcccagcagcacagcctggtcctcctggacgtgggc cgacagcaccagggcacctacacctgcatcgcctccaacgccgccggccaggccctctgc tccgcaggcttgcacgtctctggcctgcctaaggaggcgggggccatggaggagcagccc gaggtgaaggaggccctcatctccaccttcctgcaggggacccaagctgttgctgcacag atgtcagaacctgcaactttcatggaccttgctgggcagaagaaagagctcctggcagca gaggcccgtagccacctgtccttggccgaggtgggcacggaggagttcctgaagaagctc acttcacagatcacagagatggtatcagccaagatcacacaggcgaagctgcaggtgcct ggagttgacagtgacgaggagtcaaagacaccatccgcatccccccggcatggccgttca cgcccgtcttccagtgtccaggagtcgtcctcagagtccgaggatggggactcccgagga gagatctttgacatctatgtggtcacggctgactacctgcccctgggggctgagcaggat gccatcttgctgcgggagggccagtacgtggaggtcctggactctgcccaccccctgcgc tggctcgtgcgcaccaaacccaccaaaaacagcccctctcggcagggctgggtgtcccct gcctacctggacaagcggctcaagctgtctcctgagtgggggccagcggaggcccctgag ttccctggggaggctttgtcagaggacgagtacaagacgaggctgagtgccatcatccgg gacctgctgagctcagagcagtccttcgtgggcgagctgcagttcctacagagtcaccac atgcagtacctggaccgctgcccccatgtgcccgcagccgtggccagccagaaggcagtc atcttccgaaacgtgcaggacatcggccacttccacagcagcttcttacaggagttgcgt agctgtgacacagatgacgacgtggccatgtgcttcatcaagaaccaggcagcctttgag aagtatctggagttcctggtgggccgggtgcaagccgagtcggtgatggtcagcacggcc gtgcaggagttctacaagaaatacactgaggaggtgctgtcagccgcggacccctcgcag ccaccacccccaccgctgcagcacttcctggagcagccggtagagcgggtccagcagtac caggccctgctcaaggagctgatccgcaacaaggcgcggaacggccagaactgcgcgctg ctcgagcaagcctacgcggtggtgtcggccctgccgcagcgggcggagaaccagctgcac gtgtcgctcatggagaactaccccggcaccctggaggccctgggcgagcccatccgccag ggccacttcatcgtgtgggagggggcgccaggcgcgcggatgccgtggaaaggccaccac cggcatgtcttcctgttccggaaccacctggtggtctgcaagccccggcgggactcccgc accgacaccttcagctacgtcttccggaacatgatgaagctgagcagcattgacctgaac gaccaggtggagggcgatgaccgagcctttgagatctggcacgagcgggaggactctgtg cgcaagtacctgctgcaggcacggacggtcatcaccaagaactcctgggtgaaggagatc tgtggcatccagcagcgcctggccttgcccatctggcgccccccagattttgaagaagag ctggctgactgcacagctgagctgggcgagacagtcaagctggcctgccgtgtgacgggc acacccaagcccattgtcagctggtacaaagatgggaagccagtggaggtggaccctcac cacatcctcattgaagaccccgatggctcgtgcgcgcttatcctggacaacttgactggt gccgactctggccagtatatgtgctttgcagccagtgctgccggcaatgccagcaccctg ggcaaaatattggtgcaagtcccgcctcggtttgtgaacaaggtccgggcagtgcccttt gtggatggagaagatgcccagatcacctgcaccatcgaaggtgccccatatcctcagatc aggtggtacaaggatggggccctgctgacccctgggggcaaataccagaccctgagtgag ccccgcagcggcctgctggtgctggagatccgggcagctggcacagaggatctgggcatc tatgagtgtgagttggtgaaccggctgggctccaagcggagccgtgcggagctgctcatg cagagccccgtgctgcaggcccgggaacagcagcgcgtggagcggctcgcggccgtggaa gatgctgccgtcccagccccagctgccccagggcaggaaagcacgtccatccagaggaca cagacatgccctgaggctccaggaccttccacaggggatcacagcagccccagccccagc cctggggggccacctgcactccaggaggccagcccggagcccccatctatggaggctggg gccgcatccagtgaggcctggcagcaggttgaaggcgagcctccgaaggcgcctcagcct gtctcccacgagggcctcgagcagacagctcaggcacgcactgaggtcctagaacgcacg gtgcccatccggatggagggcgctgcctggccaggagcaggtgagctctgggacgtccac agccacgtgttcacagagaccacacacaggacatatgtgtaccagaccagcgacacgcct gctgcaagccccccgtccatgcaggtcaccatcgaggacgtgcaggcccagagcggcggt acagcacagttccaggctgtcatcgagggcaacccacagcccacagtgatctggtacaag gacggcacccagctgggagctgacccccggctcagccagcagcaggaagggaccacctac tccctggtgcttagggacgtgacccagcacgacgcgggcgtctacacctgcctggcccac aaccctggcggccaggtgctgtgcaaggcagagctgctgatccacggggcttccccttct ctggctacacgggacagtgagcacagctctaggaggaaactgcactccttttatgaggtc ctggaggaaattggaaggggtgtgtttggcttcgtgaagagggtgcagcacaagggcaac cagatggcctgcgctgccaagttcatcccactgcggagcaggacgcgtgcccaggcttat cgggagcgggacatcctagcaggcctgagccacccgctggtcactgcgctgctggaccag tttgagacgcggaagaccctgatcctcatcctggagctgtgttcgtcggaagagctgctg gaccgcctgttcaagaagagtgtggtgactgaggccgaggtcaaggtctacatccagcag ctggtggaggggctgcagtatctgcacagtcaaggcatccttcacctggacataaagccc cccaacatcctgatggtgcatcctgctcgggaagacattaaaatctgtgattttggcttt gcccaaaaaatcaccccgggagagccacagtacagcaagtacggctcccctgagtttgtg gcccccgagatcatcgaacagacccctgtgaacgaggcttccgacatctgggccatgggg gtcatcacctacctcagcctgacctgttcatccccatttgctggagagagtgaccgagca acccttctgaatgtcctggaagggcgggtgtcctggagtggccccatggccacccacctc agtgaggatgcccaggactttatcaaggctgctctgcagaaggccgtgggggctcggccc aatgctgccaagtgcctcgcccacccctggttccggaagtctgtgcctgcggaggaggcc cacttcatcaacaccaagcagctgaagttcctcctggctcgcagtcgctggcagcgctcc ctgatgagctacaagtccatcctggtgatgcgttccatcccagagctgctccagggcccg cccgacagcccatccctcgggattgcccggcacctgcgtggcgacgccagcgcctcctcc agcagctcctcctcctccgacaacgagttggccccgtttgcccgggccaagtcgttgcca tcctccccggtgacccactccccgctgctgcacccccggggcttcctgaggccttcggcc agcctgcctgaggaggccgaggcctgtccacctgccgcagcctcggctctgcctgcatcg ctgcagggcgaggagccagcagcagccctgggctgtgtaccccggcagagcgtcatccga agcctgttctaccagcaggtgggcgaaggcccggagctcgggggcccgtccccagggggc aggcggcaccccgcccgccggcggcaccttctcaagggtggctacttctcgggcgtcctg ccgggactccgagagccgctgctggagcaccgggcactggaggaggcggctgccatggag gagcaggctgcccggcaggccacagcagcctctttggagacggccgtgcagatgcccaga gcaagcacccaggaggcttctgtctccagccgctccctggaccgtgacccaccgaacact gccagttcctccaccaaggcctgcagcaaggggcagtgtcccgctccggctcccctgagt cctcaggatgcccaaggagagggcacgcctggagggggtgcacgtgccagggagaaggag catccagaggggaccccgcgggggctgacacggccctccgccagtagtgatgggtgctcc attcagccacaggagtcgtcccaggaccgctgtggagggcaggctgcccctttctctcag ccccagtgggtcccggccccccaggatagagccccccctgcggcattggcaccacaacct tctggctccttcccttcagggccctgcacagaggccctctcgtcatcccccagcccttcc ttcccaggaaagccacaggcctgtctgccccctgcccaagcaagcccccaggtagactct cagagcgggctgaaggccgtccctctcaccaagaggcctggatcacccagacccccagag ccagcctcccagatgggcacggagcctagcccctccctggatactgaaggcctggtccag gagacagaggacctgtccccgtcttcacccagcctacagcggcctcaggagcaggcgacc acacggaagttctccctggggtgccgtgggggctacgcaggagtggcgggctacggcacc tttgcctttgggggggacgccggtggcatgctggggcagggccccatgtgggccaagatg acctgggccgtctctcagtcctcggaggagcaggacgaggcaggtaccgagagcccactg ccccaggccagcacagcgcctgcacccgagggcgatggaaccctcccgagggcctcccag gagctgagctcgtgggaagacttcactgggggctctcaggtgtcgctcatacagatccag gacctgtccagggacccagaagcagcagacaccgtgtccctggacatctcagaggtggat cctgcctacctcaatctgtctgatctgtatgacatcaagtatctcccatttgagttcatg atctttaggaagatccctaagccggtggagccagaacgtccatcctcccctgagtctgag gctggggaggagctggctgagctcccagaggctgcgtggccctggccagccagcctggag atcacagaggagccagaggacatggaggccctgctcgggaaagctgccggcggcaggaag cgcaagtggtcacccccttcgggcagtctcttccacttccctggaaggcgctcacttctg gaggagcccacagagctggggctacgccagagggtgaaggcctcggtagcccacatctcc cgcctcctgaggggcaggcctgaaggtctggagaaggagagtcctccccggaagaaggca ggccttgcttccttccgcctgaagagcaaggaccgagcaccgtcgttcctaagggagctc tcggatgagacggtggtcctgggccagtctgtgactctggcctgccaggtggtggcccag ccagcggcacaggccacctggagtaaagatggggctcttcttgagagcagcagccgcctc ctcatctcctctacgctcaagaacttccagcttttgaccatcctggtggtgactgctgag gacctcggtgtgtacatgtgcagtgtgagcaatgcgctggggacggcggccactacggcc atcctccggaaggcagagcgcccttcttcctcgccacggccggacatcggggaggtgcat gcggacggggtgctgctggtctggaagcctgtggagtcatacggccctgtgacgtacatt gtgcagtgcagcctggaaggcggcagctggagcacgctggcctcggatgtctttgactgc tgctacctcacgggaaagctttctcggggtggggcgtacaccttccggacggcctgcgtc agcaaggcgggcatgggcccctacagcagcccctcggagcaggtcctcctgggagggccc agccgcctggcctctgaagaggagagtggtgccgcggggccggcccagcccctgcccagc atgcagaccttcgccttccagacgcagatgagaaggggccgcttcagcgtggtgcggcag tgccaggagaaggccagtgggcgcgtgctggctgccaagatcgtgccctaccacgccgcg gacagggctgctgtgctgcgggagtacgaggccctcaagggcctgcgccatccacacctg gcacagctgcaggctgcctacctcagccccaggcacctggtcctcatcttggagctgtgc tccgggcctgagcttctcccctgtctggccgagagggcctcctactcggaatcagaggtg aaggactatctgtggcagatactaagcgccacccagtacctgcatgcccagggtatcctg catctagacctcaggtcggagaacatgattgtcacagagtataacctgctcaaggtcatc gacttcggaaatgcccagagtttggcccaggagagggtcctgccctcagagagattcaag gactacatggagaccatggctccggagctcctggagggccagggcgctgtcgcgcagact gacatctgggccataggcgttacagccttcatcatgttgagcgctgagtacccggtgagc ggtgagggaacgcgagacacgcagaagggcctgcgcaaggggctcatccagctgagccgc tgctatgccgggctgtctgggggcgctgtggccttcctccgaagcacactgtgtgtgcac ccctgggtccggccgtgtgcatccagctgcctgcagagcccgtggctgacggaggagggc ccagccagctcccagcccgcggcggtgaccttcccaaccactggtctgcgcgtctttgtg cgagagcgcgaaaagaggcgggcactgctgtacaagaaacacaacctgcgctga

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