Bubalus kerabau (carabao): 129634393
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Entry
129634393 CDS
T11435
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
bke Bubalus kerabau (carabao)
Pathway
bke01521
EGFR tyrosine kinase inhibitor resistance
bke01522
Endocrine resistance
bke04010
MAPK signaling pathway
bke04014
Ras signaling pathway
bke04015
Rap1 signaling pathway
bke04066
HIF-1 signaling pathway
bke04068
FoxO signaling pathway
bke04081
Hormone signaling
bke04114
Oocyte meiosis
bke04140
Autophagy - animal
bke04144
Endocytosis
bke04150
mTOR signaling pathway
bke04151
PI3K-Akt signaling pathway
bke04152
AMPK signaling pathway
bke04211
Longevity regulating pathway
bke04213
Longevity regulating pathway - multiple species
bke04510
Focal adhesion
bke04518
Integrin signaling
bke04520
Adherens junction
bke04550
Signaling pathways regulating pluripotency of stem cells
bke04730
Long-term depression
bke04913
Ovarian steroidogenesis
bke04914
Progesterone-mediated oocyte maturation
bke05200
Pathways in cancer
bke05202
Transcriptional misregulation in cancer
bke05205
Proteoglycans in cancer
bke05214
Glioma
bke05215
Prostate cancer
bke05218
Melanoma
bke05224
Breast cancer
bke05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
bke00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
129634393 (IGF1R)
04014 Ras signaling pathway
129634393 (IGF1R)
04015 Rap1 signaling pathway
129634393 (IGF1R)
04066 HIF-1 signaling pathway
129634393 (IGF1R)
04068 FoxO signaling pathway
129634393 (IGF1R)
04151 PI3K-Akt signaling pathway
129634393 (IGF1R)
04152 AMPK signaling pathway
129634393 (IGF1R)
04150 mTOR signaling pathway
129634393 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
129634393 (IGF1R)
04518 Integrin signaling
129634393 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
129634393 (IGF1R)
04140 Autophagy - animal
129634393 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
129634393 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
129634393 (IGF1R)
04520 Adherens junction
129634393 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
129634393 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
129634393 (IGF1R)
04914 Progesterone-mediated oocyte maturation
129634393 (IGF1R)
09156 Nervous system
04730 Long-term depression
129634393 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
129634393 (IGF1R)
04213 Longevity regulating pathway - multiple species
129634393 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
129634393 (IGF1R)
05202 Transcriptional misregulation in cancer
129634393 (IGF1R)
05205 Proteoglycans in cancer
129634393 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
129634393 (IGF1R)
05214 Glioma
129634393 (IGF1R)
05218 Melanoma
129634393 (IGF1R)
05215 Prostate cancer
129634393 (IGF1R)
05224 Breast cancer
129634393 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
129634393 (IGF1R)
01522 Endocrine resistance
129634393 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bke01001
]
129634393 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
bke04090
]
129634393 (IGF1R)
Enzymes [BR:
bke01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
129634393 (IGF1R)
Protein kinases [BR:
bke01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
129634393 (IGF1R)
CD molecules [BR:
bke04090
]
Proteins
129634393 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Other DBs
NCBI-GeneID:
129634393
NCBI-ProteinID:
XP_055412552
LinkDB
All DBs
Position
19:8509451..8815642
Genome browser
AA seq
1376 aa
AA seq
DB search
MACFPTDDDRELNTSTPSGQCQLVESWAAREVFQPPPWIHVCGPGIDIRNDYQQLKRLEN
CTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKL
FYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAASNNYIVG
NKPPKECGDLCPGTMEEKPLCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTETHECC
HPECLGSCSAPDNATACVACRHYYYAGVCVPSCPPNTYRFEGWRCVDRDFCANIPNAESS
DSEGFVIHDGECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQ
GCTIFKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGE
EQLEGNYSFYVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGR
QSKGDINTRNNGERASCESDVLHFTSTTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAP
FKNVTEYDGQDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVEN
DHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQ
PQDSYLYRHNYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQA
EKEEAEYRKVFENFLHNAIFVPRPERKRREVMQIANTTMSSRGRNTTVLDTYNITDPEEL
ETEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGA
DDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGA
KLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVQAKTTYENFIHLIIALPIAVLLIVGGL
VMMLYVFHRKRNSSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFG
MVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQ
GQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKF
VHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTT
HSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQY
NPKMRPSFLEIISSVKDEMEAGFREVSFYYSEENKPPEPEELDLEPENMESVPLDPSASS
ASLPLPDRHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
4131 nt
NT seq
+upstream
nt +downstream
nt
atggcttgctttcccacagatgatgatcgggagttgaacacctccacaccctcaggccag
tgccagcttgtggaaagctgggcagcgagagaagtcttccagcctccaccttggatccat
gtctgcgggccgggcatcgacatccgcaacgactaccagcagctgaagcgcctggagaac
tgcacggtgattgagggctacctccacatcctgctcatttccaaggccgaggactaccgc
agctaccgcttccccaagctcaccgtcatcaccgagtacctgctgctgttccgcgtggct
ggcctcgagagcctgggcgacctcttccccaacctcacggtcatccgcggctggaagctc
ttctacaactacgccctggtcatcttcgagatgaccaacctcaaggacatcgggctctac
aacctgcggaatatcacccgtggggccatccggatcgagaagaatgccgacctctgctac
ctgtccacggtggactggtccctgatcctggatgcggcatccaacaactacatcgtgggg
aacaagccccccaaggagtgtggggacctgtgtccagggacgatggaggagaagccgctg
tgcgagaagacgaccatcaacaacgagtacaactaccgctgctggaccacaaaccgctgc
cagaaaatgtgccccagcgcgtgcgggaagcgggcatgcacggagacccacgagtgctgc
caccccgagtgcctaggcagctgcagcgcgcccgacaacgccacggcctgcgtggcctgc
cgccactactactacgccggcgtctgcgtgcccagctgcccgcccaacacctaccgcttc
gagggctggcgctgcgtggaccgcgacttctgcgccaacatccccaacgccgagagcagc
gactccgagggcttcgtcatccacgacggcgagtgcatgcaggagtgcccgtcgggcttc
atccgcaacgggagccagagcatgtactgcatcccttgcgaaggcccttgtcccaaagtg
tgtgaggaagaaaagaagacaaagaccattgattctgtcacttctgctcagatgctccaa
ggatgcaccatcttcaaaggcaatctgctcatcaacatccgtcgcggcaacaacatcgct
tcggaactggagaacttcatggggctcatcgaggtggtgacgggctacgtgaagatccgc
cactcccacgccttggtctccttgtccttcctgaagaacctgcgccagatcctaggggag
gagcagctagaggggaactactccttctatgtccttgacaaccagaacttgcagcagctg
tgggactgggaccaccgcaacctgaccatcaaagctgggaaaatgtactttgcattcaat
cccaaattgtgtgtctcggagatttaccgcatggaggaagtgacggggactaaagggcgc
cagagcaaaggggacataaacaccaggaacaacggggagagagcctcctgtgaaagtgac
gtcctgcacttcacctccaccaccacgtcgaagaaccgaatcatcatcacctggcaccgg
taccggccccccgactaccgggacctcatcagcttcactgtctactacaaggaagccccc
tttaaaaacgtcacggagtatgacgggcaggacgcctgcggctccaacagctggaacatg
gtggacgtggaccttccgcccaacaaggacgtggagcccggcattttgctgcacgggctg
aagccctggacgcagtacgccgtttacgtgaaggctgtgaccctcaccatggtggagaac
gaccacattcgtggggccaagagcgagatcttgtacattcgcaccaacgcatcagttcct
tccatccccctggatgtcctctcggcctcaaactcctcttctcagctgatcgtgaagtgg
aacccgccctccctgcccaacggcaacctgagctactacatcgtgcgctggcagcgccag
ccccaggacagctacctgtaccggcacaactactgctccaaagacaaaatccccatcagg
aagtacgccgacggcaccatcgacgtcgaggaggtgacggagaaccccaagaccgaggtg
tgcggcggggagaaagggccgtgctgcgcttgccccaaaaccgaagctgagaagcaggcg
gagaaggaggaggccgagtaccgcaaggtcttcgagaacttcctgcacaacgccatcttc
gtgcccagacccgaacggaagcggagggaggtcatgcagattgccaacaccaccatgtcc
agccggggcaggaacaccacggtgctggacacctacaacatcacagacccggaagagctc
gagaccgagtaccctttctttgagagcagagtggacaacaaggagagaactgtcatctcc
aacctccggccttttactctgtaccgaatcgacatccacagctgtaaccatgaggctgag
aagcttggctgcagcgcttccaactttgtctttgcaagaaccatgcctgcagaaggagca
gacgacattcctgggccggtgacctgggagccaaggcctgagaactccatctttttaaaa
tggccagaacctgagaatcccaatggattgatcctcatgtatgaaataaaatatggatcc
caagtcgaggatcagcgggaatgtgtgtccagacaggagtataggaagtatggaggagcc
aagctaaaccggctcaacccagggaactacacagcccggatccaggccacctctctctct
gggaatgggtcgtggacggatcccgtgttcttctacgttcaggccaagacgacatatgag
aacttcatccacctgatcatcgctctgcccattgcggttctgttgatagtgggaggcttg
gttatgatgctgtacgtcttccatagaaaaagaaatagcagcaggctgggaaatggagtg
ctgtacgcctctgtgaacccggagtatttcagcgcagctgatgtgtacgtgcctgacgag
tgggaggtggcccgggagaagatcaccatgagccgcgagctgggccagggctccttcggg
atggtctacgaaggcgtggccaagggcgtggtcaaggatgagcccgagaccagggtggcc
attaagacggtgaacgaggccgccagcatgcgcgagcggatcgagtttctcaatgaggcc
tcggtgatgaaggagttcaattgtcaccacgtggtgcgcttgctgggcgtggtgtcccag
ggccagccgacgctggtcatcatggaactgatgacccggggggacctcaagagttatctc
cggtctctgaggccagaaatggagaataatccagtcctagcacctcccagcctaagcaaa
atgatccagatggctggtgagattgcagacggcatggcatacctcaacgccaataagttt
gtccacagagacctcgctgcccggaactgcatggtggccgaagatttcacagtcaaaatc
ggagattttgggatgacgagagacatctatgagacggactattaccggaagggggggaag
gggctgctgcccgtccgctggatgtcccccgagtccctcaaggacggagtcttcaccact
cactctgacgtctggtcctttggggtcgtcctctgggagatcgccacgctggctgagcag
ccgtatcagggcctgtccaacgagcaggtccttcgcttcgtcatggagggcggccttctg
gacaagccggacaactgtcctgacatgctgtttgagctgatgcgcatgtgctggcagtac
aaccccaagatgcggccttcgttcctggagatcataagcagcgtcaaggacgagatggag
gcgggcttccgggaggtctccttctactacagcgaggagaacaagccgccggagccggag
gagctggacctggagcccgagaacatggagagcgtgccgctggacccctcggcctcctcg
gcctccctgccgctgcccgacagacactcaggacacaaggccgagaacggcccgggcccg
ggcgtgctggtcctgagggccagcttcgacgagaggcagccctacgcgcacatgaacggg
ggccgcaagaacgagcgcgccctgccgctgccccagtcctccacctgctga
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