Bubalus kerabau (carabao): 129650156
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Entry
129650156 CDS
T11435
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
bke Bubalus kerabau (carabao)
Pathway
bke00260
Glycine, serine and threonine metabolism
bke00630
Glyoxylate and dicarboxylate metabolism
bke00670
One carbon pool by folate
bke01100
Metabolic pathways
bke01200
Carbon metabolism
bke01230
Biosynthesis of amino acids
bke01240
Biosynthesis of cofactors
bke01523
Antifolate resistance
bke04981
Folate transport and metabolism
Module
bke_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
bke00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
129650156 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
129650156 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
129650156 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
129650156 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
129650156 (SHMT2)
Enzymes [BR:
bke01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
129650156 (SHMT2)
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NCBI-GeneID:
129650156
NCBI-ProteinID:
XP_055434323
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Position
1:66350993..66356139
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AA seq
504 aa
AA seq
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MLSFSFIWATRPLRRCGQLVGMAVRCQHSEAAQTQTGEASKGWSGQESLSDSDPEMWELL
RREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
RRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRISATSIFFESMPYKLNPQTGLIDYDQLALTARLFKPRLIIAGTSAYARLIDYARMREV
CDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVQAVD
SKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQILKNAQA
MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
PGGLRLGAPALTSRGFLEDDFRKVVGFIDEGVNIGLEVKSKTTKLQDFKSFLLKDPETSH
QLADLRQRVEQFARAFPMPGFDDH
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgttgtccttctcttttatttgggcgactcggcctctgcggagatgtggtcagctggtt
gggatggccgtacggtgccagcacagtgaggcggcccagactcagactggagaagcaagc
aagggctggtcaggccaggagagtctatcagacagtgaccctgagatgtgggagctgctg
cggagagagaaggacaggcagtgtcgcggcctggagctcattgcctcagagaacttctgc
agccgagctgcgctggaggccctggggtcctgtctgaacaacaagtactcggagggttat
cctggcaagagatactacggaggagcagaggtagtggatgagatagagctgctgtgtcag
cgccgggccttggaggcctttgacctggatcctgctcagtggggagtcaatgtccaaccc
tactccggatccccagccaatctggctgcctacacagcccttctgcagcctcacgaccga
atcatggggctggacttgcccgatgggggccatctcacccacggctacatgtctgatgtc
aagcggatctcagctacatccatcttcttcgagtctatgccttataagctgaacccccaa
accggcctcattgactatgaccagctggcactcactgctcggctcttcaaaccacgactc
atcatagctggtaccagtgcctatgctcgtctcattgactacgcccgcatgagagaagtg
tgtgacgaggtcaaggcacacctcttggcagacatggcccacatcagtggcctggtggct
gccaaggtgatcccctcacccttcaagcacgcggatattgtcaccacgaccactcacaag
acccttcgaggggccaggtcaggactcatcttctaccggaagggggtgcaggctgtggac
tccaaaactggccgagagatcccttacacatttgaggaccgaatcaactttgctgtgttc
ccatccctgcaggggggcccccacaaccatgccattgctgcagtggctgtggccctaaag
caggcttgcacccccatgttccgggagtactccctgcagattctgaagaacgctcaggcc
atggctgatgccctgctggagcgaggctactccctggtgtctggtggcactgacaaccac
ctagtgctggtagaccttcggccaaagggcctggacggagctcgagcagaacgggtgttg
gaacttgtatccatcacggccaacaagaacacctgtcctggagatcgaagtgccatcacc
cctgggggcctgcggctgggggccccagccctgacttctcgagggttccttgaagatgac
ttccggaaagttgtaggctttatagatgaaggtgtcaacattggcttggaagtgaagagc
aagaccaccaaactccaggatttcaaatctttcctgctcaaagacccagaaacaagtcat
cagctggctgaccttaggcaacgggtggaacagttcgccagggccttccccatgcctggt
tttgatgatcactga
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