KEGG   Bos taurus (cow): 281662
Entry
281662            CDS       T01008                                 
Symbol
CAPN2
Name
(RefSeq) calpain-2 catalytic subunit
  KO
K03853  calpain-2 [EC:3.4.22.53]
Organism
bta  Bos taurus (cow)
Pathway
bta04141  Protein processing in endoplasmic reticulum
bta04210  Apoptosis
bta04217  Necroptosis
bta04218  Cellular senescence
bta04510  Focal adhesion
bta05010  Alzheimer disease
bta05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:bta00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    281662 (CAPN2)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    281662 (CAPN2)
   04217 Necroptosis
    281662 (CAPN2)
   04218 Cellular senescence
    281662 (CAPN2)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    281662 (CAPN2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    281662 (CAPN2)
   05022 Pathways of neurodegeneration - multiple diseases
    281662 (CAPN2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:bta01002]
    281662 (CAPN2)
Enzymes [BR:bta01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.53  calpain-2
     281662 (CAPN2)
Peptidases and inhibitors [BR:bta01002]
 Cysteine peptidases
  Family C2: calpain family
   281662 (CAPN2)
SSDB
Motif
Pfam: Peptidase_C2 Calpain_III EF-hand_1 EF-hand_6 EF-hand_8 EF-hand_7
Other DBs
NCBI-GeneID: 281662
NCBI-ProteinID: NP_001096556
BGD-bta: BT28303
Ensembl: ENSBTAG00000012778
VGNC: 55037
UniProt: Q27971
LinkDB
Position
16:27080007..27138329
AA seq 700 aa
MAGIAAKLAKDREAAEGLGSHERAVKYLNQDYAALRDECLEAGALFQDPSFPALPSSLGF
KELGPYSSKTRGIEWKRPTEICDNPQFITGGATRTDICQGALGDCWLLAAIASLTLNEEI
LARVVPLDQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSAL
LEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELRKAPPNLFRIIQKALQKGSLLGC
SIDITSAADSEAITFQKLVKGHAYSVTGAEEVESRGSLQKLIRIRNPWGEVEWTGQWNDN
CPNWNTVDPEVRETLTRQHEDGEFWMSFNDFLRHYSRLEICNLTPDTLTSDSYKKWKLTK
MDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDQEDGESGCTFLVGLIQKHRRRQR
KMGEDMHTIGFGIYEVPEELTGQTNIHLSKKFFLTTRARERSDTFINLREVLNRFKLPPG
EYIVVPSTFEPNKDGDFCIRVFSEKKADYQVVDDEIEANIDEIDISEDDIDDGFRRLFAQ
LAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYIL
WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDDLIIDFD
NFVRCLIRLETLFRIFKQLDPENTGMIQLDLISWLSFSVL
NT seq 2103 nt   +upstreamnt  +downstreamnt
atggcgggcatcgcggccaagctggcgaaggaccgggaggcggccgaggggctgggctcg
cacgagagggcggtcaagtacctcaaccaggactacgcggcgctgcgggacgagtgcctg
gaggccggggcgctgttccaggacccctccttcccggccctgccgtcctccctgggcttc
aaggagttgggaccttactccagcaagacccggggcatcgagtggaagcggcccacggag
atctgcgataatccccaatttattactggaggagccactcgcacagacatctgccaagga
gccctaggtgactgctggctgctggccgcaattgcctccctcactttgaatgaagaaatc
ctggctcgagtcgtccccctggaccagagcttccaggagaactatgcggggatcttccac
ttccagttctggcagtacggcgagtgggtggaggtggtggtggacgacaggctgcccacc
aaggacggggagctgctcttcgtgcactcggcagagggcagcgagttctggagtgcgctg
ctggagaaggcctacgccaagatcaatgggtgttatgaagcactttcggggggcgccacc
actgagggcttcgaggacttcactggaggcatcgctgagtggtatgagttgaggaaggcc
cctcccaacctgttcaggatcatccagaaggctctgcagaaaggctctctcctgggctgc
tccatcgatatcaccagcgctgcggactcggaggccatcacgttccagaagctggtgaag
gggcacgcgtactcggtgaccggtgccgaggaggtggaaagcagaggaagcctgcagaag
ctgatccgcatccggaatccctggggagaggtggagtggaccgggcagtggaatgacaac
tgcccaaactggaacacagtcgaccccgaggtgagggaaacgctgactagacagcatgag
gatggggaattctggatgtctttcaacgacttcctgagacactattcccgcctggaaatc
tgcaacctgacccctgacacactcaccagtgacagctacaagaagtggaaactcaccaag
atggatgggaactggaggcggggctccaccgcgggcggctgcaggaactacccgaacacg
ttctggatgaatcctcagtacctgatcaagctggaggaagaggacgaggaccaggaggac
ggggagagcggctgcaccttcctggtgggcctcatccagaagcaccggcggcggcagagg
aagatgggcgaggacatgcacaccattggcttcggcatctatgaggttccagaggagttg
actggacagaccaacatccacctcagcaaaaaattcttcctgacaaccagagcgcgggag
cggtcggacaccttcatcaacctgcgggaggtgctcaaccgcttcaagctgccccccggg
gagtacatcgtggtgccctccaccttcgagcccaacaaggacggcgacttctgcatccgg
gtcttttccgagaagaaagccgactaccaagttgtcgacgatgaaatcgaggccaacatt
gacgagattgacatcagcgaggatgacatcgatgatggattcaggagactgttcgcccag
ctggccggagaggacgcagagatttctgcctttgagttgcagacaatcctgagaagagtg
ctagcaaagcgccaagatatcaagtccgacggctttagcattgagacctgcaaaatcatg
gtggacatgctcgactcggatgggagtggcaaactgggtctgaaggagttctacattctc
tggacgaagattcagaaataccaaaaaatttaccgggaaattgatgtggaccggtctgga
accatgaactcctatgagatgcggaaagcattagaagaagcaggtttcaagatgccctgt
cagctccaccaagtgattgtcgcccggtttgcagatgacgacctcatcatcgattttgac
aattttgtccggtgtttgattcgactggagacactgttcaggatatttaagcagctggac
cccgagaatactggaatgatccagcttgaccttatctcttggctgtctttttcagtactt
tga

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