KEGG   Bifidobacterium thermophilum: D805_0121
Entry
D805_0121         CDS       T02505                                 
Name
(GenBank) ketol-acid reductoisomerase
  KO
K00053  ketol-acid reductoisomerase [EC:1.1.1.86]
Organism
btp  Bifidobacterium thermophilum
Pathway
btp00290  Valine, leucine and isoleucine biosynthesis
btp00770  Pantothenate and CoA biosynthesis
btp01100  Metabolic pathways
btp01110  Biosynthesis of secondary metabolites
btp01210  2-Oxocarboxylic acid metabolism
btp01230  Biosynthesis of amino acids
Module
btp_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
btp_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:btp00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    D805_0121
  09108 Metabolism of cofactors and vitamins
   00770 Pantothenate and CoA biosynthesis
    D805_0121
Enzymes [BR:btp01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.86  ketol-acid reductoisomerase (NADP+)
     D805_0121
SSDB
Motif
Pfam: KARI_N KARI_C 2-Hacid_dh_C NAD_binding_2 F420_oxidored AdoHcyase_NAD Mur_ligase ApbA PDH_N Shikimate_DH Oxidored_nitro NAD_binding_7 OCD_Mu_crystall GFO_IDH_MocA
Other DBs
NCBI-ProteinID: AGH40388
UniProt: M4RCZ4
LinkDB
Position
137394..138446
AA seq 350 aa
MAATIWYEKDADLSVLNGKKVAILGYGSQGHAHALNLRDSGVDVVVGLRPTSKSVDYAKE
QGLAVKSVPEAVAEADIVMILLPDQYQAQVYKEQVEPNLKPGAALAFAHGFNIHYGYIKP
TEDHPVFMVAPKGPGHIVRREYTNGRGVPVVVAVEQDPRGDGWDITLAYAKALGALRAGA
IKTTFKEETETDLFGEQDVLMGGINHLCDMGFDVLTEAGYQPEIAYFEVFHELKMLVDLA
NEGGLNKARWSCSDTAQYGDYTSTVINEETKKRMEYQLKRIQDGSFAKEFMDDQAAGAPK
FKKLQEEYSHPHLETVGPKLRAMFSWNNQKDADADMTESFNGKIARTQVQ
NT seq 1053 nt   +upstreamnt  +downstreamnt
atggcagcaactatctggtatgagaaggatgcggatctctccgtgctcaatggcaagaag
gtcgccattctcggttacggctcccagggccatgcccatgcgctgaacctgcgcgattcc
ggcgttgacgtcgtcgtcggcctgcgcccgacctccaagtccgtggattatgccaaggag
cagggcctcgcggtcaagtccgtgccggaagcggtcgccgaagccgatatcgtcatgatc
ctgctgcctgatcagtaccaggctcaggtctacaaggagcaggttgagccgaacctgaag
ccgggcgctgctctggccttcgctcacggcttcaacatccactacggctacatcaagccg
accgaggatcacccggtgttcatggtcgctccgaagggcccgggccacatcgtccgtcgt
gagtacaccaacggccgtggcgtcccggtggttgtggctgtcgagcaggatcctcgcggc
gacggctgggatatcaccctggcttacgcgaaggccctcggcgctctgcgcgctggcgcc
atcaagaccaccttcaaggaagagaccgagaccgatctgttcggcgagcaggatgtcctc
atgggcggcatcaaccacctgtgcgacatgggcttcgacgtgctgaccgaggctggttat
cagccggagatcgcgtacttcgaggtgttccacgagctgaagatgctcgtcgacctggct
aacgagggtggcctgaacaaggctcgttggtcctgctctgacaccgctcagtacggcgac
tacacctccaccgtgatcaacgaggagaccaagaagcgcatggagtatcagctcaagcgc
atccaggacggctccttcgccaaggagttcatggacgaccaggctgctggtgccccgaag
ttcaagaagctgcaggaagagtactctcacccgcacctcgagaccgtcggcccgaagctt
cgcgctatgttctcctggaacaaccagaaggacgctgacgctgatatgaccgagtccttc
aacggcaagatcgctcgtacccaggtgcagtga

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