Ciconia boyciana (Oriental stork): 140652890 Help Entry 140652890         CDS       T10948                                  Symbol RYR3 Name (RefSeq) ryanodine receptor 3   KO K04963   ryanodine receptor 3 Organism cboy  Ciconia boyciana (Oriental stork) Pathway cboy04020   Calcium signaling pathway cboy04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:cboy00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     140652890 (RYR3)    04020 Calcium signaling pathway     140652890 (RYR3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:cboy04040]     140652890 (RYR3) Ion channels [BR:cboy04040]  Voltage-gated cation channels   Ryanodine receptor    140652890 (RYR3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 MIR SPRY Ins145_P3_rec RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_8 TBK1_ULD Motif Other DBs NCBI-GeneID:  140652890 NCBI-ProteinID:  XP_072720366 LinkDB All DBs Position 6:complement(36022946..36286550) Genome browser AA seq 4944 aa AA seqDB search MRDTESKYSCNTALGSFFSPFSYVEELHRNNSQPQRTRWRPGLQRPRGACARPLRQQRAS ALLEREGAPTGKDDEVVLQCVASIHKEQRKFCLAAEGLGNRLCFLEPTSEAKYVPPDLCI CNFVLEQSLSVRALQEMLANTEDNASEGFIRKAAQGGGHRTLLYGHAILLRHSFSEMYLT CLTSSRSQTDKLAFDVGLRENAAGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERY LHLSMSNGSIQVDASFMQTLWNVHPTCSGSSITEGYLLGGHVVRFFHGHDECLTIPSTDQ NDSQHKKVLYETGGAGVRARSLWRVEPLRISWSGSNIRWGQPFRLRHITTGKYLALNEDE GLAMLDREKSDTTSTAFCFRASKELKEKQDSSLKRDIDGMGVPEIKYGDSICFVQHVASA LWLTYKAQDAKSARLGPLKRKVILHQEGHMDDGLTLQRCQHEESQAARIIRNTTSLFSQF ISGNNRTLSPTALPIEEMAQTLQDLITYFQLPEEDLEHEDKQSKLRSLKNRQNLFKEEGM LALVLNCIDRLNDYNSAAHFAGFSREEHGTAWKEILNLLYKLLAALIRGNRNNCTQFSSN LDWLISKLDRLESSSGILEVLHCILIESPEALNIIAEEHIKSIISLLDKHGRNYKVLDVL CSLCVCNGVAVRANQNLICDNLLPRRDLLLQTRLINDVTSIRPNIFLGVAEGSAQYKKWY FELIIDQVDPFLTAEPTHLRVGWASTSGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLWS GRVPRAVASVNQHLLASDDVVSCCLDLGVPSISFRINGQPVQGMFENFSTEGFFFPVVSL SAGVKVRFLLGGRHGEFKFLPPAGYAPCYEALLPKEKMKLEPVKEYKRDSEGVRNLLGTT QFLSQASFIPCPIDTTQIALPFHLEKIRDKLAENIHELWGMNKIELGWTYGKIRDDNKRH HPCLVEFSKLPETEKNYNLQMSTETLKTLLALGCHIVHAHPAAEEDLKKVKLPKNYMMSN GYKPAPLDLSEVKLLPSQEFLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNKRNPRLVP YALLDERTKKSNRDSLREAVRTFAGYGYNIEPPDQEIADQTVEKVSIDKIRFFRVERSYA VKSGKWYFEFEAVTGGDMRVGWARPGCRPDIELGADDQAFVFEGSKGQRWHQGSGFFGRS WQPGDVVGCMINLEDKSIIFTLNGELLITSKGSELAFADFGIESGFVPICALGLSQIGRM NLGMDASTFKYYTMCGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKNHPHVEIWRIDG TIENPPRLKVTHKTFGTQNSNSDMIYCRLSMPIEFRSSFNFGMGVENASSDVFQKRKHSQ EIVAPSTTYFYSLRIFAGQDPSSVWVGWVTPDYHFYSENFDLNKNCTVTVTLGDERGRVH ESVKRSNCYMVWGGDVIANSQRSGRSNVDLEIGCFVDLATGMLSFTANGKELGTCYQVEP NTKLFPATFIQPTSTNLVQFELGKLKNTMPLSAAIFKSEERNPVPQCPPRLDVQTITPVL WSRMPNSFLKVETERVSERHGWVVQCLEPLQMMALHIPEENRCVDILELCEQEDLMKFHY HTLKLYSSVSALGNTRVAYALCSHVDVSQLFYTIDNQYLPGLLRSGFYDLLISIHLEHAK QAKLMMNNEFIIPVTDETRTIKLYPDETKKHGLPGVGLSTCLKPGFNFSTPCFIVTSEER QTSSPEIPLDTLKTKAISMLTEAVQCSGTHIRDPVGGQVAFQFVPVLKLIATLLIMGVFD DDDVKQVLLLIDPNVFGDHKEETEERTEKEEVTQVEEKAVEAGEKAIKETKAPAKGLLQT RLPESVKLQMCHLLNYFCDCELQHRVEAIVSFADRYVSKLQYNQKYRYNELMQALNMSAA LTAKKTKEFRSPPQEQINMLLNFELGEDCPCPEEIRDELYEFHDDLLIHCGIPLEEEEEE EEDSSLTGKLCSLMYKIKGPPKAEKVEPKEEEEKSPTTLKELISQTMVRWSQEDQIQDPE LVRIMYTLLRRQYDSIGELLQALRKAYTISAASVKDTINLLAALGQIRSLLSVRMGKEEE LLMINGLGDIMNNKVFYQHPNLMRVLGMHETVMDVMVNVLGGDRSQQIVFPKMVASCCRF LCYFCRISRQNQKAMFEHLSYLLENSSVGLAFPSMRGSTPLDVAAASVMDNNELALALEE PDLDKVVTYLAGCGLQSCPVLLAKGYPDIGWNPIEGERYLSFLRFAVFVNSESVEENASV VVKLLIRRPECFGPDLRGEGGNGLLAAMQEAIRISENPTRDLPSQAYKREGDDDAGEEEI VHMGNAIMSFYSALIDLLGRCAPEMHLIQSGKGEAIRIRSILRSLVPTEDLVGIISIPLK LSTVNKDGTVNEPDMSANFCPDHKAPMVLFLDRVYGIKDQSFLLHLLEVGFLPDLRASAS LDTVSLSTTEAALALNRYICSAVFPLLKRCAPLFSGTEHHASLVDSMLHTIYRLSKGRSL TKAQRDTIEECLLAICHHLRPSMLQQLLRRLVFDVPLLNEYCKMPLKLLTNHYEQCWKYY CLPSGMGSYGIAAEEELHLTEKLFWGIFDSLSHKFLSLLQKYDPELFRMALPCLSAIAGA LPPDYLDTRIRSTLEKQTSVDPEGNFDPKPVSTANLVLPEKLEYIVSKYAEHSHDKWAFD KTNSGWKYGVSLDENMKTHPLIRPFKTLTEKEKEIYRWPARESLKTMLAMGWSLERTKEG GEAIIHQRENEKLRSISQSSQGNGYSPAPLDLSNVVLSRELQGMVEVMAENYHNIWAKKK KMELESKGGGSHPLLVPYDTLTAKEKSRDREKAQELFKFLQVNGIIISRGLNDMELDASS MEKRFAFKFLKKILKYVDSAQEFIAHLEAIVTSGKTEKSPHDQEIKFFAKVLLPLVDQYF TNHCLYFLSSPTKTLSSSGYASNKEKEMVASLFCKLAALVRHRISLFGSDSATMVNCLHI LAQSLDTRTVMKSGSELVKAGLRAFFENAAEDLEKTSENLKLGKFTHSRTQIKGVSQNIN YTTVALLPILTSIFEHISQYQFGIDLLLGDVQVSCYRILCSLYSLGTGKNIYVERQRPAL GECLASLAAAIPVAFLEPSLNHYNPLSVFNTKSARERAILGMPDTVEEMCPEIPQLDGLI KEINDLAESGARYTEMPHVIEVILPMLCNYLSYWWERGSESVPQSAGPCCTMVTSEHLSI ILGNILKIINNNLGIDEATWMKRIAVYAQPIISKARPDLLKTHFIPTLEKLKKKAIKIVM EEEQLRADSKTDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRANWLKKPDADSDEL FRMVAEVFILWCKSHNFKREEQNFVIQNEINNLAFLTGDTKSKMSKQIARRGMAMQVKSG GQDQERKKSKRRGDLYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKTRYSHRDTDD EVKEHLRNNLHLQEKSDDPAVKWQLNLYKDILKSDEPTDPERNVERVQRISAALYHLEQV EQPLRSKKAVWHKLLSKQRKRAVVACFRMAPLYNLPRHKISNFFLSTFQRVWLEKVHEKT QYDRLILKLTTPPKKDEEEEEETEKKQPDPLHQIILYFSRSALTERSKLEDDPLYIAYSA MMAKSCQEEEEEEEEEKEKTFEEKEMEKQRTLYQQARLHDRGAAEMVLQMISASKGHTGP MVVETLKLGIAILNGGNTIVQQKMLDYLKEKKDAGFFQSLSGLMQSCSVLDLNAFERQNK AEGLGMVTEEGTLIVRERGEKVLQHDEFTRDLFRFLQLLCEGHNNDFQNYLRTQMGNTTT VNIIISTVDYLLRLQESISDFYWYYSGKDVIDESGQRNFSKALAVTKQIFNSLTEYIQGP CIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSAQIELLKELLDLLKDMVVMLLSLLE GNVVNGTIGKQMVDTLVESSSNVEMILKFFDMFLKLKDLTNSDAFKEHDPDGKGIISKKE FQKSMEAQKQYIPSEIEFLLSCAEADENDMFNYVDFVERFHEPAKDIGFNVAVLLTNLSE HMPNDSRLQSLLEPAESVLNYFEPYLGRIEIIGGAKKIERVYFEISESSRMQWEKPQVKE SKRQFIFDVVNEGGEQEKMELFVNFCEDTIFEMQLASQISETDSSERPEEEEEAEPCYVV DIGDDEEEEKSLESASAFAMACVAVKKNVANFFKMVTVKNLRKQYRKVRKMTVKEMVKVF FSFFWILFVGMFQLFFTIVWGIFQILWSTVFGGGLVEGAKNIKVTKILGDMPDPTQFGIH DDVLEAEKAEGAEHGIRAELVQFVKGEKGETDIISDIFGIHTKKEGGSKHGHDAGLGDIA EILGTDIQASLENTVRKKKGLQISEIAKEAETERKAEAEKADMEDGEKQDKAKEVQSEQL EEGKMQKKKRRHGQKIEKPEAVMANFFKALEIYQTKMLHYLARNFYNLRFLALFVAFAIN FILLFYKVTEEPLDEVEEDSNLWNSFDEEEEEEGMVFFVLEESTGYMAPALRALAVIHTI ISFVCVIGYYCLKVPLVVFKREKEVARKLEFDGLYITEQPSEDDIKGQWDRLVINTPSFP NNYWDKFVKRKVINKYGDLYGAERIAELLGLDKSALDFSPVEESKPEEASLVSWLSSIDT KYHIWKLGVVFTDNSFLYLAWYTTMSILGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHN GKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRA GGGIGDEIEDPAGDPYEMYRIVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVRED METKCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESFVWKM YQERCWDFFPAGDCFRKQYEDQLG NT seq 14835 nt NT seq  +upstreamnt  +downstreamnt atgagggataccgaaagtaaatactcctgcaatacagcactggggtcttttttttcccct ttctcctacgtagaagagctccaccgaaacaacagccaaccccagcgcacaagatggcgg ccaggcttgcagcggccacgcggcgcctgcgcaaggccgcttcgccagcagagggcgtcg gcgctgcttgagagggaaggtgctccaacgggaaaggatgacgaagtagtacttcagtgt gttgccagtattcacaaagaacaaaggaagttttgcttggcagctgagggacttgggaat cgcctgtgctttttggaaccaacatcagaagctaaatatgttcctccggacctttgcatc tgtaatttcgtccttgaacagtccttatctgtcagagcccttcaagaaatgctggccaac acagaggataatgctagtgaagggtttataagaaaggcagctcaagggggtggtcacaga accctgctgtatggccatgctatactacttcgacattcgtttagtgaaatgtatttgaca tgtttaacatcatcaagatcccagacggataaacttgcatttgatgtgggactacgagaa aatgcagcaggtgaggcatgctggtggacaatacaccctgcttctaaacaaaggtcagaa ggagaaaaagttcgaataggtgatgatcttatcctggtcagtgtgtcctctgaaagatac ctgcatctctccatgtcaaatggaagtattcaggtggatgcctcctttatgcagacgcta tggaatgtacatcctacatgctcaggaagcagtattacagaagggtatcttcttggtggg catgtagtacgttttttccatggccatgatgagtgtttgacaattccatctacagatcag aatgattcacagcacaagaaagtactttatgaaactggaggagctggtgttcgagcaagg tctttgtggagagtagaaccccttcgaataagctggagcggaagtaacatcagatgggga cagcctttccgtcttcgacatattacaacaggaaagtacttggctctgaatgaagatgaa ggacttgcaatgttagacagagagaagtcagacacaacatctactgccttttgttttaga gcatcaaaggagctaaaagaaaagcaggattctagtcttaaacgtgacattgatggaatg ggagtcccagaaataaagtacggtgattcaatctgttttgtccaacatgtggccagtgcg ttatggttgacttacaaagcacaagacgctaaatcagcacgtttaggtcccttgaaaaga aaggttatattacaccaagaaggccatatggatgatggtctaaccttacaaagatgtcag catgaggaatcccaggctgctcgaatcattcgcaatactacaagcttattcagccagttt ataagtggaaacaacagaacactatcacccactgccctgcctattgaggagatggctcag actctgcaagacctgattacttacttccagcttcccgaagaagacctggaacatgaagat aagcaaagcaagcttcggtcactcaaaaacagacaaaatctattcaaagaagagggaatg ctggcactagttttgaattgcattgatcgcttaaacgactacaacagcgcagctcatttt gcaggcttttcaagggaagaacatggtacagcatggaaagaaattttgaatctcctttac aaattgttagctgctctcattcgtggcaacagaaacaattgtactcagttttccagtaac ctcgattggctaataagtaaattggacagattagaatcttcctcaggtattttggaagtg ttgcactgcatcttgattgaaagcccagaagctttaaatataatagctgaggagcacatc aaatccattatttcattgttggataaacatgggcgcaattacaaggttctcgatgtactt tgctctctctgtgtctgtaatggagttgcagttcgtgccaatcaaaatttgatctgtgac aatctactgcctagaagagacttactcttgcaaacacgtttgattaatgatgtgacaagc ataaggccaaacatatttttgggtgttgctgagggctctgcacaatacaagaagtggtac tttgagttaataattgatcaggttgatccattcttgacggcagaacccacccatttacga gttggatgggcctctacttcaggttatgctccctatcctggaggtggagaaggatgggga ggcaatggtgttggtgatgacctgtactcttacggttttgatggccttcatctgtggtct ggtcgagtacccagagctgtagcatctgtcaatcagcatttattagcatctgatgatgtg gttagctgctgcttggatttaggtgtacccagtatttcattccgcattaatggacagcct gtacaaggaatgtttgagaacttcagtacagaagggtttttcttccctgttgtaagctta tcagcaggtgtaaaagttcgtttcttattgggtggacgtcatggagagtttaaatttctg cctcctgctggctatgctccttgttatgaagcattgcttccaaaagagaagatgaaactg gaaccagtgaaagaatataagagagattctgagggagtgaggaatttgctgggtacaaca caattcctctcccaagcttcctttatcccttgcccaatagacaccactcagattgctctt ccttttcatcttgaaaagatcagggacaaactagctgaaaatatccatgaactgtgggga atgaataaaatagaacttggctggacatatggcaagatacgggatgataataaaaggcat catccttgtcttgtggaattctcaaaattacctgagacagagaagaattataatctacaa atgtcaactgaaaccctcaaaacccttttggcccttggatgtcacattgttcatgctcat ccagcagctgaggaagatcttaaaaaagtcaaacttcctaaaaattacatgatgtcaaat ggatataaacctgcccctcttgatctttctgaagtgaaattgttgccttctcaagaattt ctagttgacaaactagcagaaaatgcacataatgtctgggcaaaagacagaataaagcaa ggatggacctatggcattcagcaggatcttaagaacaaacgtaatcctcggctagtgcca tatgcattattagatgaacgtactaaaaaatcaaacagagatagcctccgtgaagctgtt agaacatttgcaggctatggttataatattgagccacctgaccaagagatagctgaccaa acagtggaaaaagtcagcatcgacaagatacgatttttcagagtagaacggtcttatgca gtgaagtctggaaagtggtactttgaatttgaagctgtgacaggtggtgatatgcgtgtt ggctgggccaggccaggctgtcgacctgacatagagttgggagctgatgaccaagcattt gtatttgaaggaagcaaaggccagcgttggcatcaaggcagcggattctttggacgaagc tggcaaccaggagacgtggttggttgtatgataaacttggaagacaaatcaattatcttt actctgaatggagagttgcttataaccagtaaaggttcagaacttgcatttgctgacttt ggaatagaaagtggttttgttccaatttgtgcactgggtctatctcagattggtcgtatg aaccttggaatggatgccagtacattcaagtattatacaatgtgtggacttcaagaaggt tttgaaccttttgctgtcaacatgaacagagatgttgctatgtggtttagtaaacgctta ccaacatttgtcaacgtgccaaaaaatcatcctcatgttgagatatggagaattgatgga accattgagaatccacctcggttaaaagttactcacaaaacatttggcacacagaacagc aattcagacatgatatattgtcgtttgagtatgcccattgagttccgctcatcattcaac ttcggcatgggtgtggaaaacgcctcatctgatgttttccaaaaacgaaagcacagccaa gaaattgttgctccttctactacgtatttttattcactacggatatttgctggccaagac ccgtcttctgtctgggttggctgggtaacaccagactatcatttttacagtgagaatttt gacctaaataaaaattgtacagtgacagttactttaggtgatgagagaggcagggttcat gaaagtgtgaagcgcagcaattgctatatggtttggggaggagatgtaattgctaattcc cagagatcaggtcgcagtaatgttgatttagaaattggatgctttgttgacctggctact ggaatgttgtcgttcacagccaatggaaaagagcttggcacttgttatcaggttgaaccg aacacaaagctttttccagcaacttttatacagcctacgagcactaacttggttcagttt gaacttggtaaattgaagaatactatgcctttatcagctgcaatttttaaaagtgaagaa agaaatcctgttcctcagtgtccccctcgccttgatgtgcaaacaattacacctgtttta tggagcaggatgccaaacagctttctaaaagtagaaactgagcgtgtcagtgaacgtcat ggctgggttgtgcagtgtttggaacctctgcagatgatggcacttcatattccagaagaa aacagatgcgttgatattttggaactatgtgaacaagaagatttgatgaagtttcactat cacactttaaaactctatagctcagttagtgctctaggtaacactagagttgcttatgca ctttgtagccatgtggatgtatctcagctattttatacaatagataatcaatacttacct ggactcctacgttctggattctacgacttgctcattagtattcatttggagcatgccaag caagccaagcttatgatgaacaatgaatttattattccagttacagatgaaactcgaact attaaattatatcctgatgaaacaaagaagcatggtttacctggagtaggacttagcact tgtctgaaaccaggctttaatttttctactccatgctttattgtgaccagtgaagaacgt cagacatccagcccagagataccccttgatacacttaaaaccaaggccataagtatgcta acagaggcagtacagtgtagtggtactcatatacgagaccctgttggaggacaggttgca ttccagtttgttcctgttcttaaactgatagcaacattgctcataatgggagtttttgat gatgatgatgtgaagcaggtgttactcctcatcgatcccaatgtgtttggagatcacaag gaagaaacagaagagaggacagagaaggaagaagttacacaagttgaagaaaaagctgta gaagctggggagaaagcaataaaagaaacgaaagctcctgcaaagggcttattacagaca agattaccagaatctgttaagcttcagatgtgtcatttactcaattacttctgtgactgt gagctacaacatagagtggaagcaattgtatcatttgcagatcgttatgtatcaaaattg caatataatcagaaatacaggtacaatgaactcatgcaagccttgaacatgtctgctgct ttgactgccaagaagactaaagaatttcggtctcctcctcaagaacagattaatatgttg ctgaattttgaactgggagaggattgtccctgtccagaggagattcgggatgagttgtat gaatttcatgatgatcttctaattcactgtggtattccactagaagaggaggaagaggaa gaggaagattcctctttgactggcaaactctgttcattaatgtacaaaatcaaaggtcca ccaaaagcagaaaaagtagaacctaaggaggaagaagagaaatctcctactacactgaaa gaactcatatcccagactatggtgcgctggtcccaggaagatcagattcaagatccagaa ttagttcggattatgtacaccctccttcgtaggcaatatgacagcattggtgagctactg caagctctgaggaaagcatacactattagtgctgcctctgtgaaggataccattaatcta cttgcagcactgggccagattcgctcacttctcagtgtcaggatgggaaaagaggaggaa ttgctaatgattaatggattaggggatataatgaacaacaaggtgttttatcagcatcct aacttaatgagagtcttaggcatgcatgagactgttatggatgtgatggtgaatgtgctt ggcggagatagatctcagcagatcgtttttcctaagatggtggcaagctgttgtcgattc ctgtgctacttctgtcgaattagtcgtcaaaaccaaaaggccatgtttgagcatcttagt tacttactggaaaacagcagtgttggactggcatttccctcaatgagaggttcgacacca ctagatgttgcagcagcctctgtaatggacaacaatgagcttgcactagcattggaggag ccggatctcgataaggttgttacctacctggcgggttgtggcctgcagagttgtccagta ttgctggctaaaggatatccagacattggatggaatccaatagagggtgaacgttacctg tcattcttaagatttgcagtttttgttaacagtgaaagtgttgaggaaaatgcaagtgtt gttgtcaagctccttattcgacggccagagtgctttggaccagaccttagaggcgaagga ggaaatggtttgctggcagctatgcaggaagctatcaggatctcagagaatcctactcgt gaccttccctcccaggcatataaaagagaaggtgatgatgatgctggggaggaggagatt gtgcacatgggcaacgcaatcatgtcattttactcagctctcatagatttacttggacgc tgtgcaccagaaatgcatcttattcaaagtggaaaaggggaagctattcgaatcaggtca atccttcgatctttagtgccaactgaagatttggttgggattataagtataccactaaag ctgtcaacagttaacaaagatggcacagtaaatgagccagacatgtctgcaaatttctgt cctgatcataaagcacccatggtactcttcttggaccgtgtctatggtattaaggaccaa agcttcctccttcacctactggaagttggatttttaccagatttaagagcctctgcctct ttggatacagtttctctaagtaccacagaggcagctctcgcactaaataggtatatttgc tcagctgtgtttccattactcaaaagatgtgctcccctcttttctggaacagagcatcac gcctctctcgttgactccatgcttcacacaatatataggttatccaagggacgttctctt acaaaagcacaaagagacactattgaagaatgcctacttgctatttgccaccacttacgt ccctctatgctacaacagctgttgagaaggctagtttttgatgtgcccctactcaatgaa tactgtaaaatgcctctcaagcttctgacaaatcactatgagcagtgctggaaatattat tgtctgccttcaggaatgggaagctatggaattgcagcagaagaagaattacatttaact gaaaaacttttctggggcatatttgattccttgtctcataagttcctatctctcctgcag aagtatgatccagaactctttcgaatggctttgccttgtctaagtgctatagctggtgcc ttgccccctgattatttagatacacgaattaggtcaactttggaaaagcagacttcagtg gatccagaaggaaattttgatcccaaacctgtcagcacagcaaaccttgtacttcctgaa aagctggagtatattgtcagcaagtatgctgaacattcccatgataaatgggcctttgat aagactaatagtggatggaaatatggtgtttcactggatgaaaatatgaagactcaccca ttaataagaccattcaaaactttaactgaaaaggaaaaggaaatttatcgttggcctgcc agagaatcactgaaaaccatgttggccatgggatggagcctagaaaggaccaaggaagga ggagaagcaataatacatcagcgtgaaaatgaaaagctccgcagcatatctcagtctagc cagggaaatgggtatagcccggcgccacttgatctctctaatgtggtgctttctagggag cttcagggaatggttgaggtaatggcagaaaactaccataatatatgggccaaaaagaag aaaatggagttagaaagcaaaggtggaggtagtcatcctttattggtaccttacgacaca ttgacagccaaggagaaatcacgggaccgtgaaaaggcacaagagctgtttaaattcctt caagtcaatggtataatcatatctcggggtctgaatgacatggagttggatgcttcatcc atggaaaagaggtttgcctttaagtttctgaagaaaattttaaaatatgttgattctgct caagaatttattgcgcatttggaagccattgtaaccagtggaaaaactgaaaaatctcca catgaccaagaaataaaattctttgccaaagttcttttaccattagttgatcagtacttt acaaatcactgcctctacttcctgtcttctccaacaaaaacactcagtagcagtggatat gcatcaaataaggaaaaggaaatggtagcaagcctgttctgcaaactagctgctcttgtt aggcataggatctcactttttggtagtgattctgctacaatggtgaactgcctgcacatc ttagctcagtctcttgacacacgaactgttatgaaatcaggatctgagcttgttaaagct ggattgcgtgccttttttgaaaatgcagctgaagacctggaaaaaacttcagaaaatctt aaacttggaaaatttacccattcacgaacacaaatcaagggtgtttcacagaatatcaat tacactacggtagcattgttaccgatcttgacatcaatttttgaacatatttcacaatat cagtttggaattgatttacttttgggtgatgtacaagtttcatgttacagaattctttgt agcctctattcccttgggactgggaagaacatctatgttgaaaggcagcgtcctgcactt ggtgagtgcttagcatctcttgcagcagccattccagtagcattccttgaaccttccctc aaccattacaacccattgtctgtcttcaacacaaaaagtgcaagagaaagagcgatttta ggtatgcctgatacagtagaagagatgtgtccagagatccctcagttggatggactaata aaggaaattaatgatttagcagagtctggagcaaggtatactgaaatgcctcatgtaatt gaggttatcttacccatgctatgcaactatttgtcctactggtgggaaagagggtctgag agtgttcctcaaagtgctgggccttgctgtacaatggtaacatctgagcatctgagcatc attcttggaaacattctgaaaatcattaacaacaatctgggaatagatgaagcaacttgg atgaaaagaattgcagtttatgctcaacccatcatcagtaaagccaggcctgatctgctc aaaactcactttattccaacactggagaaattgaagaagaaagctataaagatcgtgatg gaagaggagcaactgagagcagatagtaaaactgacacccaagaagctgagctactcatt ctcgatgagtttgctgttctttgtagagacctttacgccttctatccaatgttgatacgt tatgtagacaacaacagagccaattggctaaagaaaccagatgcagattctgatgaactc tttcgaatggtagctgaagtttttatcctgtggtgtaaatcacataatttcaaaagagaa gaacaaaattttgtgattcagaatgaaatcaacaatttggcatttttaacaggagacacc aagagcaaaatgtctaaacagattgctcggaggggaatggccatgcaagtaaagtctgga ggacaagatcaagagagaaagaaatcaaaacgtagaggggatttgtactccatacaaaca tccttgattgtagctgcacttaaaaagatgcttcctattggtttgaatatgtgcactcct ggagatcaagagctcatctctttggctaagactagatacagccatagggacactgatgat gaagtcaaagaacatttacgtaacaacttacatttgcaggaaaagtctgatgacccagct gtgaaatggcagttaaatctgtacaaagacattttgaagagtgatgaacctactgaccct gaaagaaatgtggaacgtgtgcagaggatatcagctgctctatatcatctggaacaggtt gaacaaccactgagatcaaagaaagctgtttggcacaaactcctgtcaaaacaacgcaaa agggctgttgttgcgtgtttcagaatggcaccattatacaacctgccaagacacaaaatt agcaatttcttcctgagcacctttcaacgtgtttggctggaaaaagtacatgaaaaaact cagtatgacaggcttatactcaagttaacgacacctccaaaaaaagatgaagaggaagag gaagagactgagaaaaaacagcctgatccacttcatcagattatcctctattttagtcgc agtgctctcacagagagaagcaaactagaagatgatcctttatatattgcatattccgcc atgatggcaaagagctgtcaggaagaagaagaagaggaagaagaagaaaaagaaaagaca tttgaggagaaagaaatggaaaaacagagaactctctatcagcaagctcgcttacatgat cgtggagctgctgagatggtccttcagatgattagtgcaagcaaaggtcatacaggaccc atggttgttgaaacactaaaacttggtattgctattctaaatggtgggaataccattgtt caacagaaaatgctagactacctgaaggagaaaaaggatgctggattttttcaaagtctc tctggcttgatgcagtcctgcagtgttcttgacttgaatgcatttgagagacaaaataaa gcagaaggactgggaatggttactgaagaaggaactctcatcgttcgtgagcgtggtgaa aaagtgttgcagcatgatgaatttactcgagatctatttagatttttacaactgctctgt gaggggcataacaatgattttcaaaattacctacgtactcagatgggcaacaccacaaca gtaaatattatcattagtacagttgactatctcttgcgtcttcaggaatcaatcagtgac ttctattggtactattcaggaaaggatgtcattgatgaatcaggacaacgtaacttctct aaagctttggctgtcaccaaacaaatattcaattcccttacagaatatatccagggccct tgcataggtaatcaacagagtctggctcatagtaggctgtgggatgcagttgttggcttt cttcatgtctttgccaatatgcagatgaaactttcacaggactctgctcagattgaattg cttaaagaactgctagatctgctaaaggatatggtagtgatgctcttgtcattgcttgaa ggtaacgttgtaaatggaactattggaaaacaaatggtagacacgcttgtagaatcatct agcaatgtagaaatgattttgaagttctttgacatgttcctcaagttaaaagatctgact aactcagatgctttcaaagagcatgacccggatggtaaaggcatcatttcaaagaaggaa ttccagaaatcaatggaggctcaaaaacaatacataccatcagagattgaattcctgctg tcctgtgcagaagctgatgaaaatgatatgtttaactatgttgattttgtggaaagattc catgaaccagccaaagacattggatttaatgtagcagtattgctaacaaacctttcagag cacatgcctaatgattcacgccttcagagcttacttgaacctgcggaaagtgttcttaat tactttgaaccgtaccttggccgtattgaaataattggtggagccaagaaaatagaaaga gtttactttgaaatcagtgaatccagtagaatgcagtgggagaagccacaggtgaaggaa tccaaaaggcagttcatatttgatgttgtaaatgaaggtggagagcaagaaaaaatggaa ctctttgtgaatttctgtgaagacacaatctttgaaatgcagttagcatcccagatctct gaaacggattcatccgagaggcctgaggaagaggaagaggcagagccttgttatgtagtg gatattggagatgatgaggaagaagaaaagtccctggaatctgcttcagcttttgcaatg gcctgtgttgcagtgaaaaagaatgttgccaacttttttaaaatggtcaccgtgaagaac ctaaggaaacaatacaggaaagttagaaagatgacagtaaaagagatggtgaaagtgttt ttctcctttttctggatcctatttgtagggatgttccaactgttctttactatagtgtgg ggaattttccagattctttggagcacggtatttgggggtggcctcgttgaaggagccaaa aacattaaagttactaaaatattaggggacatgcctgacccaacacagtttggaatccat gatgatgttttggaagcagaaaaagctgaaggcgctgagcatggcatcagagctgaactt gtgcagtttgtgaagggtgaaaagggagaaactgacatcatctcagacatttttggcatt catacaaagaaagaaggtggctcaaaacatggtcatgatgctggacttggagatattgca gaaatccttggtactgatatccaggcatctttggaaaacacagttcgtaagaaaaaagga ttacagatatctgaaattgcaaaagaagctgaaacagaaagaaaagcagaagctgagaag gctgacatggaagatggtgagaaacaagataaagcaaaggaagtacaatctgagcagcta gaagagggaaaaatgcagaaaaagaagcgaaggcatggacaaaaaattgagaaaccagag gctgttatggctaacttcttcaaagctttggaaatttatcaaacaaaaatgcttcactac ttggcaagaaatttttataacttaaggtttcttgctttatttgttgcatttgccatcaac tttattcttctattttacaaggtgacagaagagccacttgatgaagtagaggaagactct aatctctggaactcttttgatgaagaggaagaggaggagggcatggtgttttttgtttta gaagaaagtacaggttacatggcacctgctctcagagcattggcagttattcacactatc atctcctttgtctgtgtgattggatactattgcttaaaggtccctctggttgtattcaag agagaaaaggaggtagctagaaagctggagtttgacggactctacataactgaacagcca tctgaagatgacattaaagggcaatgggatcgcctggttataaatactccgtcctttcct aacaattactgggacaaatttgtaaaacggaaggttattaacaagtatggagacttatat ggagcagagcgcatagcagaacttttgggtttggacaaaagtgcccttgattttagtcca gtggaagagagcaaaccagaagaggcatctcttgtatcatggttaagctccattgataca aagtaccacatttggaagctcggcgttgttttcactgataattcgtttttatacttagct tggtacacaactatgtctatacttgggcactacaacaacttcttctttgctgcgcacctg ctggatattgctatgggtttcaagacattgcgaaccattttgtcttcagtcactcacaat ggcaaacagcttgtgcttactgtaggactcctcgctgtagtagtgtatctttacactgtt gtggcgttcaacttcttccgcaaattctacaacaaaagtgaagatgaagacgaaccagac atgaagtgtgatgacatgatgacgtgttacctgttccacatgtatgtgggtgtaagagct ggtggtggcattggagatgaaattgaggatcctgctggagacccttatgaaatgtacaga attgtctttgacatcacatttttcttctttgtcattgttatcctactggccattattcaa ggtctgattattgatgcttttggtgaattaagagaccagcaagaacaagtgagagaagat atggagaccaaatgttttatttgtggaatcggcaatgactattttgacacaaccccacat ggctttgaaacacatactttgcaagaacacaacttggcaaactatctgttctttttaatg tatctcattaacaaggatgaaactgagcatactggccaggagtcatttgtgtggaagatg taccaagaaagatgttgggattttttcccagcaggggactgcttccggaaacagtatgag gatcagcttggctaa

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