Coxiella burnetii RSA 331: COXBURSA331_A0214
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Entry
COXBURSA331_A0214 CDS
T00632
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
cbs
Coxiella burnetii RSA 331
Pathway
cbs00300
Lysine biosynthesis
cbs00550
Peptidoglycan biosynthesis
cbs01100
Metabolic pathways
cbs01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
cbs00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
COXBURSA331_A0214 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
COXBURSA331_A0214 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
COXBURSA331_A0214 (murF)
Enzymes [BR:
cbs01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
COXBURSA331_A0214 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ABX78687
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Position
186052..187392
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AA seq
446 aa
AA seq
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MMKLSEAAKIVNADLTGEDTVFENVSTDTRTIQPGSLFIALRGPNFDANDFIAKAEEQGA
VGAVVNRVVKTTLPLIFVSDTLEALGRLARYQREQIPIPAIVVTGSCGKTTTRALLASVF
RQCGNVLASEKSFNNNIGVPLTLLRLRPDHHYAVLELGANHPGEITYLTGLAKPSVAIIT
NAGPVHLEGFGSLEGVAKAKGEIFEGLSSDGTAVINNDDHFAEFWRRLAHSRRIISFGIN
QPADVMAKNITLNSDGRPAFQLVLPTGQLEIQLPLIGVHNVANALAAAAAAYAQQLSTDA
IKAGLESVVPVKGRLVEQKGYRGAIIIDDSYNANPLSVSAAIAVLAKRPGHSVLVLGDML
ELGQGAEQFHQEIGKRAFEAGVKQLYCYGTLTKHTANAFGKNARHFDNQEKLLTALKNDL
NANAVVLVKGSFSMRMGNIAHALLEE
NT seq
1341 nt
NT seq
+upstream
nt +downstream
nt
atgatgaaattatctgaagccgcaaaaatcgttaatgccgatttgacaggggaagatacg
gtgtttgagaacgtgagtacagacactcgcacgattcaacccggtagtctttttattgct
ttgcgcggtcccaatttcgatgcgaatgattttattgctaaagcggaagaacaaggcgct
gtgggggccgttgtgaatcgggtagtaaagaccactttgcccctgatttttgtcagtgat
accttagaagccctggggcgattagctcgttatcaacgtgagcaaatccccattccggcg
attgtagtgacgggtagctgcggcaagacgaccacacgtgcgctcttggcgagcgtcttt
cgtcaatgcggcaatgtattggcgagcgaaaaaagttttaacaataatattggcgtgccg
ttaacattattacggttgcgtcctgatcaccattacgctgtgctcgaactgggcgctaat
catccaggtgaaattacttatttgacggggctcgccaaaccctcggtagccattattacc
aacgccggacccgtccatttggaaggttttggcagcctcgaaggcgtggccaaagccaaa
ggtgaaatttttgaaggattgtcatcggatggaaccgcggttattaataacgacgatcat
tttgctgaattttggcgtcgtttagcccattcgcgacggattattagctttggaataaac
cagccggcggatgtcatggctaaaaatatcaccctaaattcagacggacggcccgcgttc
caactcgttttgcccaccggccaactcgaaattcaattgcccttaattggtgtacataat
gtcgctaacgcactcgcggcggccgctgcggcctatgcccaacaattgtccactgacgcc
atcaaagcaggattggaaagcgtggttcctgtcaaaggacgactcgtcgaacaaaaaggt
taccgcggcgcgatcattattgatgatagctataacgccaaccccctctcagtatccgcc
gctattgcggtgttggcaaaacgacccgggcattccgttttggtattgggtgatatgttg
gagttaggccaaggtgctgaacaatttcaccaagaaatcggaaaacgcgcttttgaagca
ggcgtgaaacaattgtattgctatgggaccttaaccaaacacaccgccaacgcctttggc
aaaaatgcccgtcattttgataatcaagaaaaattattaactgcgttaaaaaacgatctc
aatgccaatgccgttgtgttagttaaagggtcgttttccatgagaatgggcaacattgcc
cacgcgttattagaggaataa
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