Canis lupus familiaris (dog): 485027
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Entry
485027 CDS
T01007
Symbol
HSD11B1L
Name
(RefSeq) hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X3
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00140
Steroid hormone biosynthesis
cfa00980
Metabolism of xenobiotics by cytochrome P450
cfa01100
Metabolic pathways
cfa05204
Chemical carcinogenesis - DNA adducts
Module
cfa_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
485027 (HSD11B1L)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
485027 (HSD11B1L)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
485027 (HSD11B1L)
Enzymes [BR:
cfa01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
485027 (HSD11B1L)
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Gene cluster
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Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
Motif
Other DBs
NCBI-GeneID:
485027
NCBI-ProteinID:
XP_005633068
Ensembl:
ENSCAFG00000018793
VGNC:
41798
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Position
20:complement(54063122..54068434)
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AA seq
332 aa
AA seq
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MKVLLLTGLGALFFSYYWDDNFDPASLQGARVLLTGASAGVGEELAYHYARLGSHLVLTA
HTEAFLQKVVGNCRKLGAPEVFYIAADMASPEVPGRVVQFALDKLGGLDYLVLNHLGATP
AGTRSRSIQGTRWLLQVNLLSYVQLTSLALPSLTDSRGSLVVVSSLLGRVPTSFSSPYSA
AKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRSSTSPLSPLPLPELPGR
RSFVFPEGSPPSSRPRAATPIETPLSRWPRPEPESSRQKRKTEKNLPAPGKSRSSEFASA
DRVPGTWSPTWKAFPQSSGPLWVTWLLLPFCR
NT seq
999 nt
NT seq
+upstream
nt +downstream
nt
atgaaggttctgctcctcacggggctgggagccctgttcttctcctactactgggatgac
aactttgaccctgccagcctccagggagcccgggtgctgctgaccggggccagcgcaggc
gtcggggaggagctggcctatcactacgctcgcctgggctcccacctggtgctcacagcc
cacaccgaggctttcctgcagaaggtggtagggaactgccggaagctgggcgctcccgag
gtcttctacatcgctgcggacatggcctcccccgaggtgcccgggcgcgtggtgcagttt
gcgctggacaagctgggagggctggactacctcgtgctgaaccacctcggcgccaccccg
gcaggcacgcggtcccggagcatccaggggacacgctggctcctgcaggtgaacttgctg
agttacgtgcagctgacctcgctggcgctgcccagcctgaccgacagcagaggctccctg
gtggtcgtgtcctcgctgctcggccgtgtgcccacgtccttctccagcccgtactcggcg
gccaagttcgcgctggacggcttcttcggctccctgcggcgggagctggacgtgcaggac
gtgaacgtggccatcaccatgtgtgtcctgggcctccgggaccgcgcctcggccgccgag
gcagtcaggagctcaacgtcaccgctgtcgccgctgccgctgcctgagctcccggggcgg
cgctccttcgtcttcccagaggggagccctccatccagccgtcccagagcggcgacaccc
atcgagacacctctgagccggtggccgaggcccgagccagagtcatcaagacagaaaagg
aaaactgagaaaaacttgccagcacctggaaagagccgcagctccgagtttgcaagcgct
gatcgtgtgccaggcacctggtcaccgacttggaaggcgtttcctcagtcatccgggcca
ctgtgggtgacatggttgctgcttccattttgcagatga
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