Cottoperca gobio: 115027778 Help Entry 115027778         CDS       T07513                                  Name (RefSeq) ryanodine receptor 3-like   KO K04963   ryanodine receptor 3 Organism cgob  Cottoperca gobio Pathway cgob04020   Calcium signaling pathway cgob04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:cgob00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     115027778    04020 Calcium signaling pathway     115027778  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:cgob04040]     115027778 Ion channels [BR:cgob04040]  Voltage-gated cation channels   Ryanodine receptor    115027778 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_1 Ago_Mid Motif Other DBs NCBI-GeneID:  115027778 NCBI-ProteinID:  XP_029317126 Ensembl:  ENSCGOG00000019256 UniProt:  A0A6J2S3B6 LinkDB All DBs Position 22:complement(12103603..12213661) Genome browser AA seq 4887 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQCVACIQKENRKFCLAAEGLGNRLCYLEPTSEAKYVPP DLCICTFVLEQSLSVRALQEMLAKSGQNSEGAAQSGGHKTLLYGHAILLRHSFSSMFLAC LKTSRSQTDKLSFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERYL HLSISNGNIQVDASFMQTLWNVHPICSGSNIEEGYLLGGHVMRLFHGHDEVVAIPGSDQS EEQQRIVNYETGKAGAKARSLWRLEPLRISWSGSHIRWGQPFRLRHLTTGHYLALTEDRG LVLQDRERSDTIATAYCFRASKEKLEQSPKRDIEGMGVAEIKYGDSLCFIMHVATGLWLS YQAPDVKSARLGPLKRRACLHSEGHMDDGLTLQRCQHEESRAARIIRNTTLLFKRFIRDL DCLGVKNRILVALPVEEVLQTLNDLITYFQLPDVELEHEERQIKLRSLKNRQNLFKQEGM LTLVSNCIDRLNVYNSAAHFGECAGSEAGAAWKDILNLLYELLAALIRGNRNNCTQFSNN LDWLVSKLERLESSSGILEVLHCILIESPEALNIIQRGHIKSIISLLYKHGRNHKILDVL CSLCVCNGVAVRTNQNLICDHLLPKRDLLLQTQLVNDVQSMRPNIFLGVSEGSAQYKKWY YELMIDQVDHFVTSEPSHLRVGWANAKGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLWS GRIPRGVASMNQHILTSEDVVSCCLDLGAPSISFRINGQPVQGMFENFNTDGLFFPVVSF SAGVKVRFLLGGRHGDFKFLPPSSYAPCYEALLPKEKMKVEPVKEYKRDAEGVRDLLGTT QFMSQASFIPTPVETSQIVMPPHLDKVRDKLAENIHELWGMNKIELGWSYGKIRDDNKRQ HPCLVDFSKLPETEKNYNLQMSTETLKTLLALGCRVVQVNPNAEGSLKKIKLPKNYMMSN GYKPSPLDLSDIKLTPGQELLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKSKRNPRLVP YVLLDERTKKSNRDSLREAIRTLIGYGYNIEPSDQEGGQAVERLSIDKVRFFRVERTYAV KTGKWYFEFESVTGGDMRVGWARPGCKPDVELGTDELAFVFDGYRGHCLNMGSRLFGRCW HAGDIVGCMINMEDKSMIFTLNGEILITSKGSELCFTDFETEDGFIPVCSLGLAQVGRMN LGKDASTFRYYTMCGLQEGFEPFAVNMNREVTMWFSKRLPTFVNVPKDHSHIAVTRIDGT VDSPPCLKVTHKTFGTQNSNADTVFCRLSMPVEFHSIFKCSPVVDMNGIQEDDTLKVKHR YPLRSVRHSDESRRVDYSIITTYYHSVRVFAGQDPASVWVGWVTPDYHYYSNNFNLSKNR SVTVTLGDERGRVHESVKRSNCYIVWCGDVTSAAHASTRSNVDLEIGCLIDLATGLVTFT VNGKEITTSYQVEPNTKLFPAVFVRPTSPNLFQFELSKIKNAMPLSSAIFKSEHKNPVPQ CPPRLDVQTINAVLWSRMPNTFLKVETARVNERHGWVVQCVEPLQMLAVHIPEENRCVDI MELSEQEDMRRFHYHTLKLYCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLSGMLREG FYNVLISTHLETAKEARLMMKDEFIIPVTAETRSIRLFSNASKKHLPPGVGLSTSLKPRL NFAPPCFISTKREQHLFSPQIPLDALKEKSILMLTEAVQGGGHHIRDPVGGGVEYQFVPI LKLISTLLTMGVLGSEDVHKILLLIDPNVFRETRDEGPSTDKEGLTGTEEKAVEAGEEEA AKEAKQPMKGLLEKRLPEPVKRQMCELLHYFCDCELKHRIEAIVSFSDSFVSKLQYNQKF RYNELMLALNMSAAVTAKKTKEFRSPPQEQINMLLTFSMGEDCPCPTGIQEELYDFHNQL QLHCGIPMEEDEYEQDTSIKGRLLMLVNKIKGQSHKAEEPTEKEQAAPSNLKELISQTMV SWAQECHILDSELVRKMFSLLRRQYDSIGELLRAMRKTYTISAASIQDTINLLAALGQIR SLLSVRMGKEEEKLMIDGLADIMNNKVFYQHPNLMRILGMHETVMEVMVNVLGGHKSQEI AFPKMVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPAMRGSTPLDVAASSV MDNNGLALALEEPDLDKVVTYLAGCGLQSCPILLAKGYPDIGWNPIEGERYLSFLRFAVF VNGESVEENSSVVVKLLIRRPECFGPALRGEGGNGLLAAMKEAIKISETRALDLPGSVHG VSSDVSADGDDEEEVVHMGNAIMSFYSALIDLLGRCAPEMHLINKGKGEALRIRAILRSL VPTEDIVGIISIPLKMPITNKDGSVTEPDMSACFCPDHKAPMVLFLDRVYGIEDQSFLLH LLEVGFLPDLRAATSLDTEGLCTTETALAMNRFIGSAMLPLLTRCAPLFAGTEHYATLID STLHTIYRLSKGRSLTKAQRDAIEECLLAVCKHLRPSMLQQLLHRLVFDVPLLTDYCKMP LRLLTNHYEQNWKYYCLPSGWGSYGTASEDELLLTKKIFWGVFDSLSQRNYDAELFKMAM PCLSAIAGALPPDYVDASISTTVEKPVSVDAQGNFDPKPISTANIALPEKLEHFANKYGE HAHEKWSAEKVLLGWKYGDGVDEKAKIHPQLRIYKALTEKEKEIYRWPIRESLKSMLAMG WSIDRNKDGESMSQQRESEKMRKISQTSQANGFNPSPIDTSNVVLSRELQGMMEVLAENY HNIWAKKRKSDLGSRGGGTHPLLVPYDTLTAKEKARDREKALDIFRFLQINGYSITRGLK DLEQDSSSMEKRFAYKFLKKLLKYVDSAQEFIAHLGYESMAANGKTDRSPHEQEIKFFAK VLLPLIDQYFKNHSLYFLSSPSKNLSSSGYASNKEKEMVTSLFCKLAALVRHRISLFGSD STTIVSCLHILAHTLDTRTVMKSGSEQVRVGLRTFFENAAEDLEKTFENLKLGKFTHSRS QMKGVSQNINYTTVALLPILTALFEHITQHHFGVDLLLDDVQVSCYRILTSLYALGTGKN IYVERQLPALGQCLATLAGAMPVAFLEPLLNAYNPCSVFNTKSARERAILGIPDSVEEMC PGMPRLDGLMKDINDMAESGARYTEMPHVIEVVLPMLCNYLSYWWERGPENQPAIGGSVC CTTVTSENLSLILGNILKILNNNLGIDEASWMKRIAVYVQPIISKARADLLKSHFLPTLE KLKKKTVKVVSEEELLKADSKGDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSRW LKEPDADSNELFRMVAEIFILWCKSHNFKREEQNFVVQNEINNLSFLTGDNKTKMSKSFK EKSGGQDQERKHKKRRGEFYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKTRYLLR DTDEEVKDHIRQNLHLRERSEDPAVRWQLNLYKDIAMRSDGPPDPERVVDRIQRISAAVF NLEQVEQPLRSKKCVWQKLLSKQRKRAVVACFRMAPLYNLPRHKTNNYFLKAYRHIWLEI MYGNTDYDSLLSMLTKTQPKVEEEEEEEVRKQPDPLHQLILHFSHNALTECSSLEEDPLY IAYADMMAKSCDEGEEEEEEEGKEKTFEEKEMEKQKMLYQQARLHDRGAAEMVLQMISAS KGRLGAMVTFTLKLGISVLNGGNILVQQRMLDYLKEKRDVGFFKSLSGLMMSCSVLDLNA FERQNKAEGLGMVTEEGSINVSERGSKVLQNDEFTKDLFRFLQLLCEGHNNDFQNFLRTQ TGNTTTVNIIISTVDYLLRLQESISDFYWYYSGKDIIDEAGQRNFSQALAVAKQVFNSLT EYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSSQIELLKELLDLQKDMIVM MLSLLEGNVVNGTIGKQMVDTLVESSSNVEMILKFFDMFLKLKDLTTSDSFKEYDPERKG VISKKDFQKSMENQKQYSQSEIEFLLSCTEADENDMFNYEQFVERFHEPAKDIGFNVAVL LTNLSEHMPHDARLATFLDLAESVLSYFEPYLGRIEIMGGAKRIERVYFEISESSRTQWE KPQVKESKRQFIFDVVNEGGESEKMELFVKFCEDTIFEMQLASQISEPDPVERPEEDEDD NQSVVENQEEEEEESVMLESSSAFTVACISMKKSLCHFRQLLTFKSMRRQYRKFRKMSVR EMVQGFFSFFWMIITGLFHFVYSLVWGFFHILWTTMFGGGLVEGAKNMKVTDILGNMPDP TQFGIHGDVLEMEKMEASEASALAEMGQLSQGDAGEADLMAELLNIQPKKEGKHGAEPGL GDVSEVVVGDAPSIASAVKQKKEQLAAKKMVVNGDYKSDSEKGDSEDGEKKDHDKSKDES PPDPPVQKKVPKKRINQKKELPEVFMASFFAGLEIYQTKMLNYLARNFYNLRFLALFVAF AINFILLFYKVTGDYSDDEDPWDGRGRTGEEEEDEGALEYFVLQESTGYMAPTLRCLAIL HTIISFLCVVGYYYLKVPLVVFKREKEIARKLEFAGLYITEQPSDDDIKGQWDRLVINTP SFPNNYWDKFVKRKVIKKYGDLYGAERIAELLGMDKSALDFNPTEETVAKEASLVSWLSS IDTKYHVWKLGVVFTDNSFLYLVWYTTMSILGHYNNFFFAAHLLDIAMGFKTLRTILSSV THNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVG VRAGGGIGDEIEDPAGDPYELYRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQV KEDMETKCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYV WKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 14664 nt NT seq  +upstreamnt  +downstreamnt atggctgaaggtggagaaggagaggatgaaatccagttcctcagaactgatgatgaagtg gtgctccagtgtgtggcctgcatccagaaggagaatcgcaagttctgcctggctgctgag ggactgggcaatcggctgtgttacctggagccaacatctgaggcaaagtatgttcctcca gacctgtgcatctgtacctttgtgctggaacagtctctgtcagtacgggccttacaggag atgctggctaagagcggacagaacagtgaaggggcagcgcagagcggcggacacaagact cttctgtacgggcacgccatcctccttcggcattccttcagctctatgttcctggcctgt ttgaagacatcaaggtcacagacagataagctgtcctttgacgtcggcctgcaggaggat tcaacaggtgaggcctgttggtggacgatccaccctgcctccaaacagagatctgaagga gagaaagtgcggattggtgatgacctcatcctcgtcagcgtgtcctcagagcgatacctt cacttatccatctcaaatggcaacatccaggtggatgcttccttcatgcaaaccctgtgg aacgtccatcccatctgctcgggaagcaacatagaagaaggctacctgctgggtggtcat gtgatgcggctgttccatggacatgacgaggtcgtggccatcccaggatcagaccagagt gaagagcagcagaggatagtcaactatgagacgggtaaagccggtgccaaggcgaggtcc ttgtggaggctggagccgctccgaatcagctggagtgggagccacatccgctgggggcaa cccttccgactgcggcacctgaccaccggtcactacttggccctcactgaggataggggg ttggtgctgcaggaccgggagaggtcagacaccatcgccaccgcctactgcttcagagca tctaaggagaagctggagcagagtcccaagcgggacatcgagggcatgggagtcgcggag attaaatacggggactcgctttgcttcatcatgcacgtggcaacgggactctggctctcc taccaggcacctgacgtcaaatctgcccgtctgggtcccctcaagagacgagcgtgccta cattctgaaggtcacatggatgacgggctgaccctgcagcgctgtcaacacgaggagtcc cgcgcggcacggatcatccgcaacaccacattactcttcaaacgattcatcagagacctg gattgtctgggtgttaagaataggatactggtagcgctgcctgtggaggaggtcctccaa acccttaatgacctcatcacctatttccagctacctgacgttgagctggagcacgaagag aggcagattaagctgcgctcgctcaagaaccggcagaacctattcaaacaggaaggcatg ctgactctggtgtccaactgtatcgatcgactaaatgtatacaacagtgccgcccacttc ggggagtgtgcggggtcagaggctggagcagcctggaaagacattctcaacctactgtac gagcttctggctgcgttaattagagggaacaggaacaactgcacccagttctccaacaac ttggactggctggttagcaagctggagagactggagtcttcttcaggcatcctggaagtt ctgcactgcattctaattgagagccccgaggccctcaacatcatccagagaggacacatc aagtccatcatatcactgctctacaagcacggacgcaaccacaagattctggatgtgctc tgctccctgtgtgtgtgtaacggcgtagctgtgcgtaccaatcagaacctaatctgcgat cacttgctgcccaaaagagatctgctgctgcaaacccagctggtcaatgatgtccagagt atgagaccgaacatcttcctgggggtgagcgagggctcggctcagtataagaagtggtac tacgagctcatgatcgaccaggtggaccactttgtgaccagcgagccctcccacctgagg gtgggctgggctaatgctaaaggctacgctccctaccctggaggaggagagggatgggga ggcaatggagtcggagatgacctctactcgtatggttttgatggactccacctctggtca ggtcgtatcccgcggggggttgcatccatgaaccagcacatcctgacctcagaagatgtg gtgagctgttgtttggatctgggagctcccagcatctctttcaggataaacgggcagccc gttcagggcatgttcgaaaatttcaacacagacgggctcttcttccccgtcgtcagcttc tctgcaggggtcaaggtgcgtttcctgttgggtggccgacatggcgactttaagttcctg cctccgtcaagttacgctccgtgttacgaagctcttctgccgaaagagaagatgaaagtg gagcctgtgaaggagtacaagagggatgcggaaggagtccgagatctgctgggcacgacg cagttcatgtcgcaggcctccttcatccccacacctgtggaaactagccagattgttatg ccacctcatttagataaggtccgagacaagctggctgagaacatccacgaactgtggggg atgaataaaattgagctgggctggtcgtacggcaagataagggatgataataagcggcag catccgtgcctggtggatttctccaagctgccagaaactgaaaagaactacaatctgcag atgtcaacagaaaccctgaagaccctgctggcattgggctgtcgtgtagttcaggttaat ccaaatgctgagggctccctcaaaaagataaaactccctaagaactacatgatgtccaat ggttataagccgtctcctctggacctgtctgacatcaaactgactccaggtcaggagctg ctggtggacaaactggcagagaacgctcacaatgtttgggccaaggaccgaatcaaacag ggatggacctacggcattcagcaggatctgaagagtaagcgtaaccctcgcctggttccc tacgttctgctggatgagcgcaccaagaagtcgaacagggacagcctgcgggaggctatc cgcactctgattggctacggatacaacatcgagccctcggaccaggaaggcggacaagcg gtcgagcggctcagcatcgacaaggtccgcttcttcagagtggagcggacgtacgcggtg aagacagggaagtggtattttgaattcgagtctgtgacgggaggagacatgagagtgggc tgggccaggcctggatgtaagccggatgtggagcttggcacggatgagctcgcgttcgtc tttgatggatacaggggtcactgcctgaacatgggcagccgtttgttcgggcggtgctgg catgctggggacatcgtgggctgtatgatcaacatggaggacaagtccatgatcttcacc cttaacggagagatcctcatcaccagcaagggctctgaactctgcttcactgactttgaa actgaggatgggtttattccagtgtgcagtctcggcctggctcaggtgggccgtatgaac ctggggaaagacgccagcaccttcaggtactacaccatgtgcggccttcaggagggattc gaaccctttgctgtcaacatgaaccgagaggtcaccatgtggttcagcaagcgtctgcct acctttgtcaacgtgccaaaggaccacagccacatcgcagtgaccaggattgacggcacc gtcgacagcccgccgtgtctcaaagtcacccacaagacttttggcacccagaacagcaac gcagatacggtgttttgtcgcctcagcatgcctgtagagttccactccatcttcaaatgc agtcctgttgtagacatgaacggaatccaagaggacgatactcttaaagtcaaacacaga tatcctttgaggtctgtgaggcacagcgatgaaagcagacgagtggactacagcatcatc acgacgtactaccactcggtaagggtcttcgctggtcaggaccctgccagtgtgtgggtt ggatgggttactcccgactaccattactatagcaacaacttcaacctcagtaaaaaccga tcggtcactgtaaccctgggtgacgagcgaggacgagtccatgagagtgtgaagaggagt aactgctacatcgtgtggtgtggggatgtgaccagcgctgctcacgcctccactcgcagc aacgtggacctggagatcggctgtctcatagacctggccaccggcctggtgacattcact gtcaacggcaaagagataaccacatcctaccaggtggaaccaaacaccaagcttttcccc gctgtgtttgtgcgacccaccagccctaacctcttccagttcgagctgtctaagataaag aatgccatgcctctatcatccgccatctttaagagtgaacataagaacccggtgccccag tgtccaccccgtctagacgtccagaccatcaacgccgtgctgtggagccgcatgcccaac accttcctcaaggtggaaacggcccgggtcaatgagagacatggctgggtggtccagtgt gtggagcccctgcagatgttggctgttcatatacctgaggagaacaggtgtgtcgacatc atggagctgtctgagcaggaggacatgaggaggttccactaccacaccttaaagctctac tgtgccctctgcgcacttgggaacacccgtgtggcccacgccctctgcagccacctggac caatcacagctcttatacaccatcgacaatcagtacctgtcaggcatgttacgagagggc ttctacaacgtcctgatcagcacccacctggagacggcgaaagaggcacgactcatgatg aaagacgagttcatcatccccgtcacggcagaaacgcgctccatccgcctcttctccaat gcttctaaaaagcaccttccgccaggggtggggcttagtacttcgctcaaaccccgcctc aactttgctccgccgtgtttcatcagcaccaaacgggagcaacatctctttagtccccaa atccccctggacgcattgaaggagaaatcaattttaatgttgacggaggccgttcagggt ggcggacaccatatacgagatcccgtcggaggaggcgtggagtaccagtttgtgccaatt ttaaagctcatcagcaccctgctgactatgggtgtactaggtagcgaggacgtgcacaag atcttgctgctcattgaccctaatgtttttagagagacccgcgatgagggtccttccaca gacaaagaaggacttacggggacggaggagaaggcagtggaggctggagaagaggaggcc gccaaagaggccaaacagccaatgaagggactgctggagaagaggctgcctgagcccgtc aaacgacagatgtgtgagctgcttcactatttctgcgactgcgagctgaagcaccgcatc gaggccatcgtgtctttctccgacagcttcgtatccaagctgcagtacaaccagaagttc cgctacaacgagctgatgcttgccctcaacatgtctgctgccgttaccgcaaagaagacc aaagagtttagatcgccccctcaagaacagatcaacatgctgctgaccttcagtatgggc gaagactgtccgtgtccaacaggcatccaggaggaactgtatgattttcacaaccagctg cagctccactgtggaatccctatggaggaagacgaatatgagcaagacacatcgatcaaa ggtcgcctcctgatgctggtgaacaagatcaaaggccagtctcacaaagcagaggagccc acagagaaggagcaagcggcaccatccaatctgaaggagctgatctctcagacgatggtc agctgggcccaggagtgtcacatcctggactcggagctggtccgcaagatgttcagcctg ctgaggaggcagtacgacagcatcggggagctgctccgggccatgaggaagacttacacc atcagtgctgcctcgatccaggacaccatcaacctcctggccgccctcggtcagatcaga tctctgctgtctgttcgtatggggaaagaggaggagaagctcatgattgatggacttgct gacatcatgaacaacaaagtattctaccagcaccccaacctaatgagaatactcggcatg cacgagaccgtcatggaggtcatggtcaatgtgctcggaggacacaagtcccaggaaatc gccttccccaagatggtggccagctgctgtcgcttcctgtgctacttctgccggatcagc cgtcagaaccagaaagccatgttcgaccacctcagctacctgctggagaacagcagcgtg ggcctagcttcaccagcgatgaggggctccactcctctagatgtggctgcttcctcagtg atggacaacaacggcctggctctggcactggaggagcctgatctcgacaaggttgtcacc tacctagcgggctgtggtctccagagttgtccaatactcctggctaaaggttatccagac atcggctggaaccccatcgagggggagcgttacctttccttcttgcggtttgctgtcttt gtcaacggcgagagcgtggaggagaactccagcgttgtggtcaagttgctcatccgtcgt ccagagtgttttggacccgccctgaggggggagggaggcaacggcctgctggccgccatg aaggaggccatcaagatctctgagacgcgggctctggacctgccgggctctgtgcacgga gtcagctctgacgtgtctgctgatggtgacgatgaggaggaggtggtacacatgggcaat gccatcatgtccttctactctgcgctcatcgacctgctgggacgttgcgccccggagatg catctcatcaacaaggggaagggtgaggctctgcgtattcgtgccatcctgcgctctctg gtgcccactgaagacattgtgggaatcatcagcataccgctcaaaatgcccatcaccaac aaagatgggtcggtgactgagccggacatgtcggcctgcttctgtccggatcacaaggcc cccatggtgctgtttttggacagggtgtatggaatcgaggaccagagctttctgcttcac ctgctcgaagtgggcttccttcctgacctcagggctgctacctctctggatacggaggga ctttgtacaacagagacagccctggccatgaaccgcttcatcggctcagccatgcttccc ctccttacccgctgcgcccctctctttgccggcaccgagcactacgccaccctcatcgac tccactctgcacaccatctaccgcctttccaagggccgctcactcaccaaggcccagaga gacgccatagaggagtgcctgctggctgtctgcaagcaccttcgtccctccatgctgcag cagctcctgcaccgcctcgtctttgacgtgcccttgctgactgattactgcaagatgcct ctcagactgctaaccaaccactatgagcagaactggaagtactactgcctcccgtcgggc tggggcagctacggcacagcatccgaggatgaactactgctcaccaagaaaatcttctgg ggagtatttgattctctgtcccagaggaattatgacgccgagcttttcaagatggccatg ccttgcctcagtgccatagctggagctttgccaccggactacgtggacgcctccattagt accactgtggagaagcctgtttctgtagatgctcagggcaactttgaccccaaacccatc agcactgcaaacattgctcttccagagaagcttgagcactttgccaacaaatatggagag cacgcccatgagaaatggtcagcagagaaggtgctgctgggctggaaatatggagacggt gtggacgagaaggccaagattcaccctcagctcagaatctacaaagccctgacagagaag gagaaagagatttacagatggccaattagagagtccctgaagagtatgctggcaatgggc tggagcatcgacaggaacaaggatggagagagcatgtctcagcagagggagagtgagaaa atgcgaaagatctctcagacttcacaggcaaatggcttcaatccgagcccgatagacacg agcaacgtggttctatccagagaattacaggggatgatggaggtgttggctgaaaattac cataacatctgggccaagaagagaaagagtgaccttggaagcagaggcgggggaacacac cctctgttggtgccctacgacacgctgacagccaaggagaaggcccgtgatcgagagaag gccctggacattttccgtttcctgcagatcaacggctatagcatcacaaggggtttgaaa gacttggagcaggattcctcctccatggagaagaggttcgcttacaagttcctcaagaag ctgctcaagtatgtcgactcagcgcaggagttcatcgctcacctagggtatgagtccatg gctgccaatggcaagacagatcggtcccctcatgaacaagaaatcaagttttttgccaaa gttcttctccctctcatcgaccagtacttcaagaaccactccctctacttcctctcctcc cccagtaagaacctgagcagcagcggttacgcctccaacaaagagaaggagatggtcacc agcctgttttgtaaactggcagctcttgtcagacataggatttctctctttgggagcgac tccactaccatcgtcagctgtctgcacatcctggcacacactctggacaccaggacggtg atgaagtcgggctcggagcaggtgagggtggggctgaggacgttcttcgagaacgccgca gaggacctggagaagacgtttgagaacctgaagctggggaagttcactcactctcgctcg cagatgaaaggggtgtcgcagaatatcaactacaccaccgtggctcttctccccattcta accgctctgtttgagcacatcactcaacaccactttggagtcgacctgcttttggatgat gtccaagtgtcctgctatcggatcctgaccagtctctatgcactgggtactgggaaaaac atctacgtagaaaggcagctcccagctctcggtcagtgcctggccaccctggctggagcc atgcctgtggccttcctggagccactattaaacgcgtacaacccctgctccgtctttaat accaagagtgccagagaacgagccatcctcggcataccagactcagtcgaggagatgtgt cccgggatgcctcgcctggacggtctgatgaaggacatcaacgacatggccgagtctggg gcgcggtacacggagatgcctcacgtcatcgaggtggtgctgcccatgctgtgtaactat ctgtcctactggtgggagagggggcccgagaaccagccagccatcgggggcagcgtctgc tgcaccaccgtcacctcagaaaacctcagcctcattctcggcaacatcctcaagatcctc aacaacaacctcggcatcgacgaggcctcctggatgaagagaattgcagtgtatgtacaa cccatcatcagcaaggcccgtgctgacctgctgaagagccacttcctgcctacgctggag aaactgaagaagaagacggtgaaggtggtgtcagaggaagagctgctgaaggcagacagt aagggagacacccaggaggccgagctgctcatcctggatgagtttgccgtactctgcagg gacctgtacgccttctaccccatgcttatccgctatgtggacaacaacaggtcgaggtgg ctgaaagaaccagacgctgactccaacgagctcttcagaatggtcgctgagatatttatc ctctggtgcaaatcacacaatttcaaaagagaagaacagaactttgtggtccagaatgaa atcaacaacctttccttcttgaccggagataataaaaccaagatgtctaagtcctttaag gagaagtctggaggacaagaccaggagaggaaacacaagaaaaggcgtggtgagttctac tctatccagacctcgctgattgtggccgctctgaagaagatgctgcccatcggcctcaac atgtgtaccccaggagaccaggagctcatctctttagccaagactcgctacctcctgaga gacacggacgaagaggtcaaagatcatattcggcagaatctgcaccttcgagaaaggtca gaggaccccgcagttaggtggcagctaaacctgtacaaggatatagcgatgagaagcgac gggcctccggaccctgagagggtggtggaccgcatccagaggatctctgctgctgtcttc aacctggagcaggtggagcagccgttgagatccaagaaatgtgtatggcagaagttgctg tccaagcagaggaagcgagcggtcgtcgcctgcttccgcatggctccactttataacctg ccaaggcacaaaactaataattacttcctgaaagcctaccgacatatttggctggagata atgtatgggaacacagactatgacagtctgctctccatgctgacgaaaacgcagcccaaa gtggaggaagaggaggaggaggaggtcagaaagcagccagaccctcttcaccagctcatt ctgcatttcagccacaacgctctgactgagtgcagttctttagaagaggatcccttgtat attgcatatgcagatatgatggcaaagagttgtgatgaaggtgaagaggaagaagaagag gaaggaaaagagaaaacatttgaggaaaaggaaatggagaagcaaaagatgctgtaccag caagccagactacatgatcgaggagctgcggagatggtgcttcagatgatcagtgccagc aaaggtcgacttggtgctatggtgactttcaccctcaaactaggcatctccgtcctcaac gggggaaacatactggtgcagcagagaatgctggactacctgaaggaaaaaagagatgtt ggctttttcaaaagtttgtctggactcatgatgtcttgcagtgtcctggatttaaatgca tttgaaaggcaaaataaagctgaaggcctggggatggttactgaagaaggatcaatcaac gtgagtgagcggggttccaaggtgctgcagaatgatgagtttactaaggatctctttagg tttctgcagcttctctgtgagggccacaacaacgattttcagaacttcctgaggactcag acggggaacacaactacagttaacatcatcattagtactgtcgactacctactaagactt caggaatccatcagtgatttctactggtactactctggtaaggatattatagatgaggca ggtcagaggaacttctcccaggcgctggcagtggccaagcaggtcttcaactctttaact gagtatatacagggtccatgtattgggaaccagcagagtctggctcacagcaggctgtgg gacgcagtggtgggcttcttgcatgtttttgccaacatgcagatgaagttatcccaggac tccagtcagattgagttattgaaggagctgctagacctgcagaaggacatgatcgtcatg atgctctcccttctcgaaggtaatgttgtcaatggtaccattggcaaacaaatggtggac accttggtggaatcttccagcaacgtggagatgatcctaaagtttttcgacatgttcctc aagttgaaggacctgaccacctcggacagcttcaaggagtacgaccccgagcgcaaaggg gtcatctcgaagaaagatttccagaagtccatggagaaccagaaacagtactcccagtct gagattgagtttctcctctcgtgcactgaggcagacgagaacgacatgttcaactacgag cagtttgtggagagatttcatgaacccgccaaggacattggctttaatgtagccgtgttg ctgactaatctctctgagcatatgcctcacgatgctcgcctcgcgacgttcctcgacctg gctgagagcgtcctcagctactttgagccttatttgggtcgtattgagatcatgggtgga gccaagcgcatcgagagagtttactttgagatcagtgagtcgagtcgcacccagtgggaa aagcctcaggtgaaagagtcaaagcggcagtttatctttgacgtcgtcaacgaaggtggg gagagcgagaagatggagctctttgtcaaattctgcgaagacaccatctttgagatgcag ctggcttctcaaatttcagagcccgacccagtggagcgtccagaagaagacgaggacgac aaccagagtgtggtggaaaaccaggaggaggaagaggaggaaagtgtcatgttggagtct tcctcagcgtttacagtcgcctgcatctccatgaaaaaaagcctctgccactttcgccag ctgctcactttcaagagcatgaggcggcagtacagaaagttccggaagatgagcgttcgg gagatggtgcaaggcttcttctctttcttctggatgatcatcacaggcctcttccacttt gtctacagcctggtttggggtttctttcacatcttgtggaccaccatgttcgggggcggc ctcgtcgaaggggccaagaacatgaaggtgacggacatcttgggaaacatgccagacccc acccagtttgggatccacggcgacgtgttagagatggagaagatggaggcaagtgaagct tcggcgttggcggagatgggtcagttgtctcagggagacgcaggagaggcagacctgatg gctgagttgctgaacatacagcccaagaaggagggaaagcacggggctgagcctgggttg ggggatgtgtctgaggtggtggtgggggatgctccgtccattgccagcgctgtgaagcag aagaaggaacaattggctgcaaagaagatggttgtaaatggagactacaaatctgattca gagaaaggagattcagaagatggtgagaagaaggaccatgacaagtccaaagacgaatcc cctccagatcctccagtgcagaagaaagtccccaagaagaggatcaaccagaagaaagaa cttccagaggtcttcatggccagcttcttcgctggcttggaaatctaccagaccaagatg ctgaattatttggccagaaacttctacaaccttcgtttcctggcactttttgtcgccttt gcgatcaactttattctgctcttctacaaagtgacaggtgattactcagacgatgaagac ccctgggatggtcgaggcagaactggggaggaggaggaagatgagggtgcacttgagtat ttcgtcctgcaggagagcacgggctacatggcgccaacgcttcgctgtctggctattcta cacaccatcatatctttcctgtgtgtagttggatactactacctgaaggtgccactggtc gtgttcaaacgtgagaaggagatagcgaggaagttggagttcgccggcctttacatcacg gagcagccgtcagacgatgacatcaaaggacagtgggacagattggtcatcaatactcct tccttccccaacaactactgggataaatttgtcaaacgcaaagtgatcaaaaagtacgga gacctgtatggagctgagaggatagcagagctgctggggatggacaagagcgccctggat ttcaaccctacggaggaaactgttgccaaggaggcttcactggtgtcatggttgagctca atcgacacaaagtaccatgtgtggaaattgggggtggtgtttacagataattccttcctg tatctagtgtggtacaccactatgtccatactgggccactacaacaacttcttcttcgct gctcacctgctggacatcgccatggggttcaagacccttcgcaccatcctctcctctgtc acacataacggcaaacagctggtgttgacggtgggcctgctggcagttgtggtctatctc tacactgtggtggccttcaacttcttcaggaagttctacaacaagagcgaggacgaggat gagccagatatgaagtgtgacgacatgatgacttgttacctgttccacatgtacgtcggg gtgagagcaggagggggcattggggatgagatcgaggacccagctggggacccctatgag ctctaccgcatcctttttgacatcactttcttcttcttcgtcatcgtcattctcctggcc atcatccagggtttgatcatcgatgcctttggagagctgagagaccagcaggaacaagtc aaagaggacatggagaccaaatgtttcatttgtgggatcggtaacgactactttgacaca acacctcacggctttgagactcacaccttacaagagcacaatttggccaactacctgttc ttcctgatgtacctcatcaacaaggacgagacggagcacactggccaggagtcatacgtg tggaagatgtaccaggagcgctgctgggatttcttcccagctggagattgcttccgcaaa cagtacgaagatcagctcggatag

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