Capra hircus (goat): 102182663
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Entry
102182663 CDS
T02910
Symbol
CYP17A1A
Name
(RefSeq) steroid 17-alpha-hydroxylase/17,20 lyase precursor
KO
K00512
steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:
1.14.14.19
1.14.14.32
]
Organism
chx
Capra hircus (goat)
Pathway
chx00140
Steroid hormone biosynthesis
chx01100
Metabolic pathways
chx04913
Ovarian steroidogenesis
chx04917
Prolactin signaling pathway
chx04927
Cortisol synthesis and secretion
chx04934
Cushing syndrome
Module
chx_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
chx_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
chx_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
chx_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
chx00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
102182663 (CYP17A1A)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
102182663 (CYP17A1A)
04917 Prolactin signaling pathway
102182663 (CYP17A1A)
04927 Cortisol synthesis and secretion
102182663 (CYP17A1A)
09160 Human Diseases
09167 Endocrine and metabolic disease
04934 Cushing syndrome
102182663 (CYP17A1A)
09180 Brite Hierarchies
09181 Protein families: metabolism
00199 Cytochrome P450 [BR:
chx00199
]
102182663 (CYP17A1A)
Enzymes [BR:
chx01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.14.19 steroid 17alpha-monooxygenase
102182663 (CYP17A1A)
1.14.14.32 17alpha-hydroxyprogesterone deacetylase
102182663 (CYP17A1A)
Cytochrome P450 [BR:
chx00199
]
Cytochrome P450, animal type
CYP17 family
102182663 (CYP17A1A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
p450
ZSWIM4-8_C
Motif
Other DBs
NCBI-GeneID:
102182663
NCBI-ProteinID:
NP_001301074
UniProt:
Q9N0U7
A5HEW1
LinkDB
All DBs
Position
26:28275067..28281034
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AA seq
509 aa
AA seq
DB search
MWVLLGVFLLTLAYLFWPKTKHSAAKYPRSLPSLPLVGSLLFLPRRGQQHENFFKLQEKY
GPIYSFRLGSKTTVMIGHHQLAREVLLKKGKEFSGRPKVATLDILSDNQKGIAFADHGAH
WQLHRKLVLNAFALFKDGNLKLEKIINQEANVLCDFLATQHGQSIDLSEPLSLAVTNIIS
FICFNFSFKNEDPALKAIQNVNDGILEVLSKEILLDIFPALKIFPSKAMEKMKGCVETRN
ELLNEILEKCQENFTSDSITNLLHILMQAKVNADNNNAGPDQDSKLLSNRHMLATIADIF
GAGVETTTSVIKWIVAYLLHHPSLKKRIQDSIDQNIGFNRTPTISDRNCLVLLEATIREV
LRIRPVAPMLIPHKAIIDSSIGDLTIDKGTDVVVNLWALHHNEKEWQQPDLFMPERFLDP
TGTQLISPSLSYLPFGAGPRSCVGEMLARQELFLFMSRLLQRFNLEIPDDGKLPSLEGNP
SLVLQIKPFKVKIEVRQAWKEAQAEGSTS
NT seq
1530 nt
NT seq
+upstream
nt +downstream
nt
atgtgggtgctcttgggtgtctttctgctcaccctcgcctatttattttggcccaagacc
aagcactctgctgccaagtaccccagaagcctcccatccctgcccctggtgggcagcctg
ctgttcctccccagacgtggccagcaacacgagaacttcttcaagctgcaggaaaaatat
ggccccatctattcctttcgtttgggttccaagactactgtgatgattggacaccaccag
ttggccagggaggtgcttctcaagaagggcaaggaattctctgggcgtcccaaagtggcc
actctagacatcctgtcagacaaccaaaagggcattgcctttgccgaccatggtgcccac
tggcagctgcatcggaagctggtactgaatgcctttgccctgttcaaggatggcaacctg
aagttagagaagatcattaatcaggaagccaacgtgctgtgtgatttcctggctacccag
catggacagtccatagatctgtccgagcctctctctctggcggtcaccaacataatcagc
tttatctgcttcaacttctccttcaagaatgaggatcctgccctgaaggccatacaaaat
gtcaatgatggcatcctggaggttctgagcaaggaaattctgttagacatattccctgcg
ctgaagattttccccagcaaagccatggaaaagatgaagggttgtgttgaaacgcgaaat
gaattgctgaatgaaatccttgaaaaatgtcaggagaacttcaccagcgactccatcact
aacttgctgcacatactgatgcaagccaaggtgaatgcagacaataacaacgctggccca
gaccaggattcaaagctgctttcaaacagacacatgctcgctaccatagcggacatcttc
ggggctggtgtggagaccaccacctctgtgataaagtggatcgtggcctacctgctacac
catccttcgttgaagaagaggatccaggatagcattgaccagaatataggtttcaatcgc
accccaaccatcagtgaccggaactgccttgtcctgctggaggcgaccatccgagaggtg
ctccgaatccggcctgtggcccctatgctgatcccccacaaggctatcattgactccagc
attggcgaccttaccattgacaagggcacagacgttgtggtcaacctgtgggcactgcat
cacaatgagaaggagtggcagcagcccgacctgttcatgcccgagcgcttcttggacccc
acggggacacaactcatctcgccatcgttaagctacttgccctttggagctggaccccgc
tcctgtgtaggtgagatgctagcccgccaggagctcttcctcttcatgtcccggctgctg
cagaggttcaacctggagatcccggatgatgggaagctaccctctctggagggcaatccc
agtctcgtcttgcagatcaaacctttcaaggtgaagatcgaggtgcgccaggcctggaag
gaagcccaggctgagggtagcacctcatga
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