Citrobacter sp. FDAARGOS_156: AL515_05230
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Entry
AL515_05230 CDS
T04313
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
cif
Citrobacter sp. FDAARGOS_156
Pathway
cif00300
Lysine biosynthesis
cif00550
Peptidoglycan biosynthesis
cif01100
Metabolic pathways
cif01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
cif00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
AL515_05230
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
AL515_05230
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
AL515_05230
Enzymes [BR:
cif01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
AL515_05230
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
YAcAr
Motif
Other DBs
NCBI-ProteinID:
AMH13287
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Position
1125217..1126575
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AA seq
452 aa
AA seq
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MISVTLSQLAEILRGELKGADLALDAVTTDTRKVTPGCLFVALKGERFDAHDFADKAQES
GAGALLVSRPLDTNLPQLIVNDTRLAFGELAAWVRAQVPARVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLNNDYDYAVIELGANHQGEIAWTVGLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIFTGLSANGIAIMNADNNDWLNWQSIIGDRKVWRFS
PNAANSDFSAANVHVTSHGTEFSLQTPTGSIDVLLPLPGRHNIANALAAAALSMAVGATP
EAIKAGLKDLQAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLSEMPGYRVLVVGD
MAELGAESEACHVQVGIAAKAAGIDRVLSTGKLSQAISHASGVGEHFADKTALTAHLKAL
IAEHQIMTILVKGSRSAAMEEVVRALQENGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattagcgtaacgctcagccaactggcggagatcctccgtggcgaactgaaaggggcc
gatctggcccttgatgcggtgacaaccgatacgcgtaaagtgacgccgggctgcctgttt
gtggcactgaaaggcgaacgctttgatgcccatgattttgcagacaaagcgcaagagagc
ggggccggtgcgctgttggtcagccgcccgttggacaccaacctgccgcagctgattgtt
aacgatacgcgtctggcgtttggtgaactggctgcgtgggttcgcgcccaggttccggcg
cgcgttgtcgcgctgaccggctcatccggtaaaacctctgttaaagagatgacggctgcc
attctgagccagtgtggtaacaccctatataccgcgggcaacctgaataacgacatcggc
gtaccgatgacgctgctgcgcttaaacaacgattatgactatgccgtgattgaacttggc
gccaatcatcagggtgaaatcgcctggaccgttgggttgacgcgtccggaagcggcgctg
gtgaacaacctggccgccgcgcatctggaaggcttcggttctctggcgggcgtggcgaag
gcaaaaggtgagatttttaccggcctgtcagcgaacggtatcgccattatgaatgccgac
aacaacgactggctgaactggcaaagcatcatcggcgatcgcaaagtctggcgtttttcg
ccgaatgcggctaacagcgacttttcggcggccaacgtacatgtgacctcgcatggcacg
gaattttctctgcaaacgccgaccggaagcattgatgtcctgctgccgttaccgggtcgc
cataatatcgctaacgcccttgcggcggcggcgctttctatggcggtaggcgcgacgcca
gaggcgatcaaagcgggtctgaaagatttgcaagcggtcccgggacgtctgtttccgatt
caactcgcggaaaatcagctgctgctggacgactcctataacgctaacgtcggctcaatg
accgcagcggtgcaggtgctgtctgaaatgcctggctaccgcgtactggtcgttggcgat
atggcagagcttggcgcggaaagtgaagcctgccacgtgcaggtgggtatcgctgcgaag
gcggcgggtatcgaccgtgtgctgagtacagggaaactgagtcaggcaattagccatgcc
agcggcgttggtgagcattttgcggataaaaccgcgctgaccgcgcatcttaaagcgctg
attgcagaacatcagatcatgacgattttagtgaagggttcacgtagtgccgccatggaa
gaggtagtacgcgcattacaggagaatgggacatgttag
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