KEGG   Cavia porcellus (domestic guinea pig): 100727133
Entry
100727133         CDS       T07777                                 
Symbol
Cad
Name
(RefSeq) CAD protein isoform X2
  KO
K11540  carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
Organism
cpoc  Cavia porcellus (domestic guinea pig)
Pathway
cpoc00220  Arginine biosynthesis
cpoc00240  Pyrimidine metabolism
cpoc00250  Alanine, aspartate and glutamate metabolism
cpoc01100  Metabolic pathways
cpoc01240  Biosynthesis of cofactors
Module
cpoc_M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:cpoc00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    100727133 (Cad)
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    100727133 (Cad)
   00220 Arginine biosynthesis
    100727133 (Cad)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:cpoc01002]
    100727133 (Cad)
Enzymes [BR:cpoc01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.2  aspartate carbamoyltransferase
     100727133 (Cad)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.3  dihydroorotase
     100727133 (Cad)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)
     100727133 (Cad)
Peptidases and inhibitors [BR:cpoc01002]
 Cysteine peptidases
  Family C26: gamma-glutamyl hydrolase family
   100727133 (Cad)
 Metallo peptidases
  Family M38: beta-aspartyl dipeptidase family
   100727133 (Cad)
SSDB
Motif
Pfam: CPSase_L_D2 CPSase_L_D1 GATase CPSase_sm_chain OTCace_N OTCace CPSase_L_D3 ATP-grasp Dala_Dala_lig_C MGS ATPgrasp_Ter Amidohydro_1 DHOase ATP-grasp_3 Peptidase_C26 GARS_A
Other DBs
NCBI-GeneID: 100727133
NCBI-ProteinID: XP_003472918
Ensembl: ENSCPOG00000003826
UniProt: A0A286XHU1
LinkDB
Position
Unknown
AA seq 2248 aa
MAALVLEDGSVLQGRPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNY
GVPSDELDEFGLSKWFESSKIHVAGLVVGECCPSPSHWSATRTLHEWLQQHGIPGLQGID
TRELTKKLREQGSLLGKLVQNGTEPSSLPFLDPNAQPLVPEVSTKTPQIFNAGGTPRILA
LDCGLKYNQIRCLCQRGAEVTVVPWDHALDSQEYEGLFLSNGPGDPASYPSVVSTLSSIL
AKPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGSGRCFLTSQNHGFAVE
ADSLPAGWSPLFTNANDGSNEGIVHDSLPFFSVQFHPEHHAGPSDMELLFDIFLETVTEA
VAGNPGGWTVRERLVERLCPPGPPASGSGLPPLRKVLILGSGGLSIGQAGEFDYSGSQAI
KALKEENIQTLLINPNIATVQTSQGLADKVYFLPITPHYVTQVIRNERPDGILLTFGGQT
ALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEAAHSLEQ
AQAAAERLGYPVLVRAAFALGGLGSGFASTKEELSALIAPAFAHTSQVLVDKSLKGWKEI
EYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDKEYQFLRQTAIKVTQHLG
IVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRN
SVTGGTAAFEPSLDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMAIGRSFEEAFQKAL
RMVDENCVGFDHTVKPVSDMELETPTDKRIFVVAAALWAGYSVDRLYELTRIDRWFLQRM
KRIVTHAQLLEQHRGQPLPPDLLHQAKRLGFSDKQIALAVLSTELAVRKLRQELGICPVV
KQIDTVAAEWPAQTNYLYLTYWGNTHDLPFQTTHVMVLGSGVYRIGSSVEFDWCAVGCIQ
QLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLP
NNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQD
VGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAV
ACDGVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTLERIKAIVHAVGQELQVTGPFN
LQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRIIMGEKVEPVGLMTGSGVVG
VKVPQFSFSRLAGADVVLGVEMTSTGEVACFGESRCEAYLKAMLSTGFKIPKKNILLTIG
SYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSI
LEQLAENHFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEAL
GQIGPTPPLKVHVDCMTSQKLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGVTMV
CAMPNTQPPIIDAPALALAQKLAEAGARCDYALFLGASSENAGTLGAVAGSAAGLKLYLN
ETFSELRLDSVAQWMEHFETWPAHLPIVAHAERQSVAAILMVAQLMQRSVHICHVARKEE
ILLIKAAKAQGLPVTCEVAPHHLFLSQGDLERLGPGKGEVRPELGSRQDLEALWENMAVI
DCFASDHAPHTLEEKCGARPPPGFPGLETMLPLLLTAVSEGRLTLDDLLQRLHHNPRRIF
HLPPQEDTYVEVDLEHEWTIPSHLPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVL
VPPGYGQDVRKWPQGAVPQPPPSAPATSEMTTTPERPRRGIPGLPDGRFHLPPRIHRASD
PGLPAEEPKEKASRKATELELMGTPDSTYYPPPPVPRQASPQNLGAAGLHPQPSPPLQSL
VGQHILSVKQFTKDQMSHLFNVAHTLRMTVQKERSLDILKGKVMASMFYEVSTRTSSSFA
AAMARLGGSVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELASKHCRKP
VINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLARLLTLYRVSL
RYVAPPSLRMPPNVWNYVASRGIKQEEFESIEEALPDTDVLYMTRIQKERFGSAQEYESC
FGQFILTPHIMTRAKEKMVVMHPMPRVNEISVEVDSDPRAAYFRQAENGMYIRMALLATV
LGSASLASFLQAQLLGKDTQCPPRGQHP
NT seq 6747 nt   +upstreamnt  +downstreamnt
atggcggccctggtgttggaggatgggtcggtgctgcagggccggccctttggggccgcc
gtgtcgactgcaggcgaagtggtgttccaaaccggcatggttggctaccccgaggccctc
accgacccttcctacaaagcgcagatcttagttctgacctatccgctgatcggcaactac
ggcgtcccctccgatgagctggatgagttcggcctcagcaagtggttcgaatcctcaaag
atccacgtggcaggactggtggtgggagagtgctgccccagcccaagccactggagtgcc
acccgcaccctgcatgagtggctgcagcagcatggcatccctggccttcaaggaatagac
actcgagagctgaccaagaagttgcgtgaacaagggtctctcttgggaaagctggtccag
aatgggacagagccttcatccctgccattcttagaccccaatgcccaacctctggtgcca
gaggtctccactaagactccacagatattcaatgcaggcggtacccctcgcatccttgct
ttggactgtggcctcaagtacaatcaaatccgatgtctttgccagcgtggggctgaggtc
actgtagtgccctgggaccatgcattagacagccaggagtatgaggggctcttcctaagt
aatggtcctggagatcctgcctcctaccccagtgtggtatccacactgagcagtatctta
gccaagcctaatccccgacctgtctttgggatctgcctgggacaccagctgttggcctta
gccattggagccaagacatacaagatgaggtatgggaaccgaggccataaccaaccctgc
ctgctggtgggctcgggacgctgctttctgacatcccagaaccatgggtttgctgtggaa
gccgactccctgccagcaggttggtctcctctcttcaccaatgccaatgatggctccaat
gaagggattgttcacgacagcctgccatttttcagtgtccagttccacccagagcaccac
gctggcccttcagatatggaactgctttttgatatctttctggagactgtgacagaagct
gtagctgggaaccctggaggctggacagtccgagagcgactggttgaacgcctctgtccc
cctggacctcctgcctctggctctggacttccacctttacggaaggttctgatcctgggt
tcagggggcctctccattggccaagctggagagttcgactattctggctctcaggcaatt
aaggccctgaaggaggagaatatccagacactgctgatcaaccccaacattgccacagtg
cagacctctcaggggctggccgacaaggtctatttccttcctataactcctcactacgta
acccaggtgatacgcaatgagcgcccagatggcatattactgacttttgggggccagaca
gccctgaactgtggcgtggaactgaccaaggctggtgttctggctcggtacggggtccgg
gtgctgggtacccctgtggaaaccattgaactgactgaagatcgacgtgcctttgcggct
aggatggcagagattggcgagcacgtggcccccagtgaggcagcacattctcttgagcag
gcccaggcagctgctgaaaggctgggctaccctgtgctggtgagggcagcctttgcactg
ggaggcctaggctcgggctttgcctctaccaaggaggagctctcggctctcatagcccct
gcttttgctcataccagccaggtgctagtggacaagtccctcaagggctggaaggagatt
gagtatgaggtggtgagagacgcctatggcaactgtgtgacggtatgtaacatggagaac
ttagacccactaggcattcatactggtgagtccatcgtggtggcaccaagtcagacactg
aatgacaaagagtaccagttcttgcggcagacagctatcaaggtgacccagcatctgggg
atcgttggggagtgcaacgtgcagtatgccttgaacccggagtccgagcagtattacatc
attgaagtgaacgccaggctctcccgaagctctgccctggccagtaaggccacaggctat
ccactggcctacgtagcagccaagctggcactgggcattcccctgcctgagctcaggaac
tctgttacagggggaacagcagcctttgaacccagcctggactattgtgtggtaaagatt
cctcgctgggacctcagcaaattcctgcgtgtcagcacaaagattgggagttgcatgaag
agcgttggggaggtcatggccattggacgttcgtttgaggaggccttccagaaggccttg
cgcatggtagatgagaactgcgtgggctttgaccacacagtgaagccagtcagcgacatg
gagttggagacaccaacagataagcgaatcttcgtggtggccgctgctctgtgggcaggt
tactcggtagaccgcctgtatgagcttacacgcatcgaccgatggttcctgcaaagaatg
aagcgcattgtcactcatgcccagctcctggagcaacaccgtgggcagcctttgccccca
gacctgctgcaccaggccaagcgcctcggtttctcagacaagcagatcgcccttgcagtt
ctgagcacagagctggctgttcggaagctgcgtcaggaactggggatctgtccagtggtg
aagcagatcgacacagttgcggccgagtggccggcccagacgaattacctgtacctgacc
tactggggcaacacccatgatctcccctttcagacaactcacgtcatggtccttggctct
ggtgtctaccgcatcggctccagcgtcgagtttgactggtgtgctgttggctgcatccag
cagctccgtaagatggggtataagaccatcatggtgaactacaatccagagacggtcagt
accgactacgacatgtgtgaccgactgtactttgatgagatctctttcgaggtggtgatg
gacatctatgagctggagaatcccgaaggtgtgatcttgtccatgggaggacagctgccc
aacaacatggccatggctttacatcggcagcagtgccgggtgctgggcacctcccctgaa
gccattgactctgctgagaaccgattcaaattttcccggctccttgacaccattggtatc
agccagcctcagtggcgggagctcagtgacctagagtctgctcgccagttctgccaggat
gtggggtacccctgtgtggtgcgcccctcctatgtgctgagtggtgccgcgatgaatgtg
gcctacactgatggggacctggagcgcttcctaagcagtgcagcagctgtctccaaggag
caccctgtggtcatctccaaattcatccaggaggccaaggagattgatgttgacgctgtg
gcctgtgatggtgtggtggctgctattgccatctctgagcacgtggagaatgcaggtgtg
cattcaggcgatgccacactggttacccccccacaagatatcactgccaagaccctggag
cgtatcaaagccatcgtgcatgctgtgggccaggagctgcaggtcacaggacccttcaat
ctgcagctcattgccaaggacgatcagctgaaagttattgaatgcaacgtgcgtgtctct
cgctccttcccctttgtctccaaaacactaggtgttgacctagtagccttggccacacga
atcatcatgggggaaaaggtggaacccgtggggctcatgactggctctggagtcgtgggt
gtaaaggtgcctcagttctccttctcccgcttggcgggtgctgatgtggtgttgggtgtg
gagatgaccagtactggggaggtggcctgctttggggagagccgttgcgaggcctacctc
aaggccatgctaagcactggctttaagatccccaagaagaacatcctgctgaccatcggc
agctataagaacaaaagcgagctgctccctactgtgcggctgctggagagcctgggctac
agcctctacgccagtctgggcacagctgacttctacactgagcacggcgtcaaggtaaca
gctgtagactggcactttgaagaagcagtagatggtgagtgtcccccacagcggagcatc
ttggagcagctggcggagaaccacttcgagctagtgattaacctgtcaatgcgtggagct
gggggccggcgtctctcctccttcgtgaccaagggctaccgtacacggcgcctggctgct
gacttctctgtgcccctcatcatcgatatcaagtgcaccaaactctttgtggaggctctg
ggccagattgggccaacccctcctctgaaggtacatgttgactgcatgacctcccagaag
ctcgtgcggctgcctggattgattgacgtccatgtgcacttgagggagccaggtgggaca
cacaaggaggactttgcctcaggtacagccgctgctctggccgggggtgtcaccatggtg
tgtgccatgcctaacacccagccgcccattattgatgcccctgctctggctctggcccaa
aagctagcagaagctggcgcccgctgtgactatgcactcttccttggggcctcgtccgaa
aatgcagggaccctgggcgctgtggcagggtctgcggcagggctgaagctctacctcaac
gagaccttctctgagttgcggctggacagtgtggcccagtggatggagcacttcgagacc
tggccagcccacctgcccattgtggcccatgcagagcggcagagtgtcgctgccattctc
atggtggctcagctgatgcaacgctcagtgcacatatgtcacgtggcacggaaggaggag
atcctgctaatcaaagctgcaaaggcacaggggctaccagtgacctgtgaggtggcccct
caccacctgtttctgagccagggggacttggagcgcctggggcccgggaaaggggaggtc
cggcctgagctgggctcccgccaggacctagaagccctctgggagaacatggctgtcatc
gactgttttgcctcagaccatgccccccacaccctggaggagaagtgtggggcccggcct
ccacctggcttcccagggctagagaccatgctgccactgctgctgacggctgtgagcgag
ggccggctcactctggatgacctgctgcagcgactgcaccacaatcctcggcggatcttc
cacctgccaccacaggaggacacctacgtggaggtggatctggagcatgagtggacaatc
cccagtcacttgcccttctccaaggcccactggacaccctttgaagggcagaaggtgaag
ggcaccgtccgccgtgtggtcctgcgaggggaggttgcctacattgacggacaggtgctg
gtgcccccgggctatggacaggatgtgcggaagtggcctcagggggctgttcctcagccc
ccaccctcagcccctgccaccagtgaaatgaccacgaccccagagaggccacgccggggc
atcccagggcttcccgatggccgcttccacctgccaccccggatccaccgagcctccgac
ccaggtcttcctgccgaggagcccaaggaaaaagcttctcggaaggcaaccgagctagag
ctgatgggaaccccagacagcacctactaccctccaccaccagtaccgagacaggcatca
ccccagaacctgggggctgctggcctgcatccccagccctcaccgccactgcagtcacta
gtgggccagcacatcctgtctgtgaagcagttcaccaaagatcagatgtcccaccttttc
aatgtggcacacactctgcggatgacagtacagaaagagcgaagtctcgacatcctcaag
ggcaaggttatggcctccatgttctatgaagtgagcacgcgaaccagtagctcctttgca
gcagccatggcccggcttgggggctccgtgctcagcttctcggaagccacatcctccgtc
cagaagggcgagtccctggccgactcagtgcagaccatgagctgctacgccgacgtggtt
gtgctccggcacccccagcccggagcagtggagctggcatccaagcactgccggaagcca
gtgataaatgctggagatggggttggagagcaccccacacaggccctgctggatatcttc
accatccgggaggagctggggactgtcaatggcatgacgatcaccatggtgggagacctg
aagcacggacgcacagtacactccttggcccgcctgctcaccctgtaccgtgtcagcctg
cgctacgtggcgccccccagcttgcgcatgccgcccaacgtgtggaactacgtagcctcc
cgggggatcaagcaggaggagtttgagagcatcgaggaggcactgcccgacaccgacgtg
ctatacatgactcgaatccagaaggagcgctttggctctgcccaggagtatgaatcctgc
ttcggtcagttcatcctcaccccacacatcatgacccgagccaaggagaagatggtggtg
atgcaccctatgcctcgtgtgaacgagataagtgtggaggtggactcggacccccgagca
gcctacttccgccaggctgagaacggcatgtatatccgcatggctttgttagccacggtc
ctgggctcagcctccttggcatcttttcttcaggcccagctgctgggcaaggacactcag
tgccccccacgggggcagcacccttag

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