| Entry |
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| Symbol |
PDE8B
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| Name |
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1
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| KO |
| K18437 | high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53] |
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| Organism |
csum Capricornis sumatraensis (Sumatran serow)
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:csum00001]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
138073550 (PDE8B)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
138073550 (PDE8B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
138073550 (PDE8B)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
138073550 (PDE8B)
Enzymes [BR:csum01000]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
138073550 (PDE8B)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
2:complement(92094870..92317892)
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| AA seq |
885 aa
MGCAPSIHVSQSGVIYCRDSDESSSPRQTTGVSQGPAAPLHGLFVQTDAADAIPQSRASG
SPGAARARRARGELGSGSSTGSAGPAATTCRGRRRHCCSSAEAETQTSFTSVKQVSSAEV
RIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYSCNIARTPESALECFLDKHHEII
VIDHRQTRNFDAEAVCRSIRATNPSEHAVILAVVSQTSSNYEEASVLPLLHAGFNRRFME
NSSIIACYNELIQIEHGEVLSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFER
MMGYHKGELLGKELAELPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVK
ITPVIGQGGKIRHFVSLKKLCCTTDKNKQILKIHHDSGDNSQTESHSFRYKNRRKESVDV
KSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLE
ILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHSHLAMPVTI
SDVPPSIAQLLDNEESWEFNIFELEAVTHKRPLVYLGLKVFSRFGVCEFLHCSETTLRAW
LQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHP
GRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDSKCNIFKNIDRNHYRTLRQAI
IDMVLATEMTKHFEHVNKFVNSINKPMAAEIDGSDCECSPPGKNFPENQTLIKRMMIKCA
DVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYF
ITDMFDAWDAFAHLPTLMQHLADNYKHWKTLDDLKCKSLRLPSDN |
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| NT seq |
2658 nt +upstreamnt +downstreamnt
atgggctgcgcccccagcatccacgtctcgcagagcggcgtgatctactgccgggactcg
gacgagtccagctcgccccgccagaccaccggcgtgtcgcagggccccgcggcccccctg
cacggcctcttcgtccagaccgacgccgccgacgccatcccccagagccgcgcgtccggg
tccccaggcgccgcccgcgcccgcagggcccgcggggagctgggcagcggcagcagcacg
ggctccgcgggccccgcggcgaccacctgcaggggccggaggcgccactgctgcagcagc
gcggaggccgagacccagaccagcttcaccagcgtcaagcaggtttcttctgcggaggta
cgcatcgggcccatgagattgacacaggatcctatccaggttttgctcatctttgcaaag
gaagatagtcagagtgatggattctggtgggcctgtgacagagccggttacagctgcaat
attgctcggactccagagtcagccctggaatgctttctagataaacatcatgagattatt
gtaatcgatcacagacagactcgaaacttcgatgcagaagcagtgtgcaggtcaatccgg
gccacgaacccctcagagcatgcagtgatcctcgccgtggtctcacaaacatccagcaac
tatgaagaggcctctgtgctcccccttctgcacgcgggcttcaacaggagatttatggag
aacagcagcataattgcttgctacaatgaactgattcaaatagaacatggggaagttctc
tcacagttcaaattaagggcctgtaattcagtgtttacagcattagaccactgtcacgaa
gccatagagatcacaagcgatgaccacgtgatccagtacgtcaacccagccttcgaaagg
atgatgggctaccacaaaggtgaactgctggggaaagaactcgccgagctgcccaaaagc
gacaaaaaccgggcagaccttctcgacaccattaacacctgcatcaagaagggcaaggag
tggcagggggtctactacgccagacggaaatccggcgacagcatccagcagcacgtgaag
atcacgccggtgatcggccaaggagggaaaatcaggcatttcgtctccctcaagaaactg
tgttgtaccactgacaaaaacaagcagattctgaagattcatcatgattcaggagacaat
tctcagacagagtctcattcattcagatacaagaacaggaggaaagagtccgttgatgtg
aaatcaatatcatctcgaggcagtgatgcaccaagtctgcagaaccgtcgctacccatcc
atggcacggatccactccatgaccatcgaggcgcccatcacgaaggttataaatataatc
aatgcagcccaagaaaacagtcctgtcacagtggcagaagccttggacagagttttagaa
attttacgaactacagaactgtactcccctcagctgggtaccaaagatgaagatccccac
accagtgatctcgtgggcgggctgatgactgatggcttgagaaggctgtcaggaaacgag
tacgtgttcactaagaacgtgcaccagagtcatagtcaccttgcgatgccagtaaccatc
agtgatgtccccccctccatcgcccaattactagacaatgaggaaagctgggagttcaac
atctttgagctggaagctgtgacgcacaaaaggccattggtttacctgggcttgaaagtt
ttctcccggtttggagtatgtgaatttctacactgttctgaaactactcttcgggcctgg
ctccaggtgattgaagccaactaccactcttccaatgcttaccacaactccactcatgcc
gctgacgtcctgcacgccacagccttcttcctcggcaaggagagagtgaagggaagcctc
gatcagctggacgaggtggccgccctgatcgctgccacagtccacgacgtggaccacccg
ggaaggaccaactctttcctgtgcaacgccggcagtgagctcgctgtgctctacaatgac
accgctgtcttggagagtcaccacacggccctggcctttcagctcacggtcaaggacagc
aaatgcaacattttcaagaatatcgacaggaaccactatcgaacactgcgccaggctatt
attgacatggttttagcaacagagatgacaaaacactttgaacatgtgaacaaatttgtg
aacagcatcaacaagccaatggcagctgagattgatggcagcgactgcgagtgcagccct
cccgggaagaacttccctgagaaccagaccctgatcaaacgcatgatgatcaagtgtgcg
gacgtagccaacccctgccgccccttggacctgtgcattgaatgggctggcaggatctct
gaggagtactttgcgcagacggatgaagagaagagacaggggctgcccgtagtgatgcca
gtgtttgaccggaatacctgtagcatccccaagtcccaaatctcctttattgactacttc
ataacagacatgtttgatgcttgggatgcctttgcacacctgccaacgctgatgcaacat
ttggccgataactacaaacactggaagacattagacgacctaaagtgcaaaagtctgagg
cttccatctgacaattaa |
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