Cuculus canorus (common cuckoo): 104059034 Help Entry 104059034         CDS       T08597                                  Symbol RYR3 Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism cuca  Cuculus canorus (common cuckoo) Pathway cuca04020   Calcium signaling pathway cuca04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:cuca00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     104059034 (RYR3)    04020 Calcium signaling pathway     104059034 (RYR3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:cuca04040]     104059034 (RYR3) Ion channels [BR:cuca04040]  Voltage-gated cation channels   Ryanodine receptor    104059034 (RYR3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 Ins145_P3_rec MIR SPRY RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_8 TBK1_ULD Motif Other DBs NCBI-GeneID:  104059034 NCBI-ProteinID:  XP_053925030 LinkDB All DBs Position 5:complement(58952699..59173080) Genome browser AA seq 4884 aa AA seqDB search MAEGGEGGEDEIQFLRTDDEVVLQCVASIHKEQRKFCLAAEGLGNRLCFLEPTSEAKYVP PDLCICNFVLEQSLSVRALQEMLANTAENASEGAAQGAGHRTLLYGHAILLRHSFSEMYL TCLTSSRSQTDKLAFDVGLRENAAGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSER YLHLSMSNGSIQVDASFMQTLWNVHPTCSGSSITEGYLLGGHVVRFFHGHDECLTIPSTD QNDSQHKKVLYETGGAGVRARSLWGVEPLRISWSGSNIRWGQPFRLRHITTGKYLALNED EGLAMLDREKSDTTSTAFCFRASKELKEKQDSSLKRDMDGMGVPEIKYGDSVCFVQHVAS ALWLTYKAQDAKSARLGPLKRKVILHQEGHMDDGLTLQRCQHEESQAARIIRNTTSLFSQ FISGNNRTLSPTALPVEEMAQTLQDLITYFQLPEEDLEHEDKQSKLRSLKNRQNLFKEEG MLALVLNCIDRLNDYNSAAHFAGIAREEHGTAWKEILNLLYKLLAALIRGNRNNCTQFSR NLDWLISKLDRLESSSGILEVLHCILIESPEALNVIAEEHIKSIISLLDKHGRNYKVLDV LCSLCVCNGVAVRANQNLICDNLLPRRDLLLQTRLINDVTSIRPNIFLGVAEGSAQYKKW YFELIIDQVDPFLTAEPTHLRVGWASTSGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLW SGRVPRAVASVNQHLLASDDVVSCCLDLGVPSISFRINGQPVQGMFENFSTEGFFFPVVS LSAGVKVRFLLGGRHGEFKFLPPAGYAPCYEALLPKEKMKLEPVKEYKRDSDGVRDFLGT TQFLSQASFIPCPIDTSQVALPFHLEKIRDKLAENIHELWGMNKIELGWTYGKIRDDNKR HHPCLVEFSKLPETEKNYNLQMSTETLKTLLALGCHIVHAHPAAEEDLKRVKLPKNYMMS NGYKPAPLDLSEVKLLPSQEFLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNKRNPRLV PYALLDERTKKSNRDSLREAVRTFAGYGYSIEPPDQEITDQTVEKVSVDKIRFFRAERSY AVKSGKWYFEFEAVTGGDMRVGWARPGCRPDIELGADDQAFVFEGSKGQRWHQGSGFFGR SWQPGDVVGCMINLDDKSIIFTLNGELLITSKGSELAFADFGIESGFVPICALGLSQIGR MNLGMDASTFKYYTMCGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKNHPHIEICRID GNIESPPRLKVTHKTFGTQNSNSDMIYCRLSMPIEFHSSFNFGMGVENASSDVFQKRKHS QEIIASSSTYFYSLRIFAGQDPSSVWVGWVTPDYHFYSENFDLNKNCTVTVTLGDERGRV HESVKRSNCYMVWGGDVIANSQRSGRSNVDLEIGCFVDLTTGMLSFTANGKELGTCYQVE PNTKLFPAAFVRPTSTNLIQFELGKLKNTMPLSAAIFKSEERNPVPQCPPRLDVQTITPV LWSRMPNSFLKVETERVSERHGWVVQCLEPLQMMALHIPEENRCVDILELCEQEDLMKFH YHTLKLYSSVSALGNTRVAYALCSHVDISQLFYTIDNQYLPGLLRSGFYDLLISIHLEHT KQAKLMMNNEFIIPVTDETRTIKLYPDEKKKHGLPGVGLSTCLKPGFSFTTPCFIVTSEE HQTSSPEIPLDILKSKAISMLTDAVQCSGTHIRDPVGGQVAFQFVPVLKLIATLLIMEVF DDDDVKQVLLLIDPTVFGDHKEETEERTEKEEVTQVEEKAVEAGEKAIKETKAPAKGLLH TRLPESVKLQMCHLLNYFCDCELKHRVEAIVSFADRYVSKLQYNQKYRYNELMQALNMSA ALTAKKTKEFRSPPQEQINMLLNFQLGEDCPCPEEIRDELYEFHDDLLIHCGIPLEEEEE EEEDSSFTGKLRSLVYKIKGPPRAEKVEPKEEEEKSPTTLKELISQTMVRWSQEDEIQDP ELVRIMYTLLRRQYDSIGELLQALRKAYTISATSVKDTINLLAALGQIRSLLSVRMGKEE ELLMINGLGAIMNNKVFYQHPNLMRVLGMHETVMDVMVNVLGGDKSQHITFPKMVASCCR FLCYFCRISRQNQKAMFEHLSYLLENSSVGLAFPSMRGSTPLDVAAASVMDNNELALALE EPDLDKVVTYLAGCGLQSCPVLLAKGYPDIGWNPIEGERYLSFLRFVVFVNSESVEENAS VVVKLLIRRPECFGPDLRGEGGNGLLAAMQEAIRISENPARDLPSQAYKRESDDEEEEEE EIVHMGNAIMSFYSALIDLLGRCAPEMHLIQSGKGEAIRIRSILRSLVPTEDLVGIISIP LKLSTVNKDGTVNEPDMSANFCPDHKAPMVLFLDRVYGIKDQSFLLHLLEVGFLPDLRAS ASLDTVSLSTTEAALALNRYICSAVFPLLKRCAPLFSGTEHHASLVDSMLHTIYRLSKGR SLTKAQRDTIEECLLAICHHLRPSMLQQLLRRLVFDVPLLNEYCKMPLKLLTNHYEQCWK YYCLPSGMGSYGIAAEEELHLTEKLFWGIFDSLSHKFLSLLQKYDPELFRMALPCLSAIA GALPPDYLDTRITSTLEKQTSLDPEGNFDPKPVSTAHLVLPEKLEYIVSKYAEHSHDKWA FDKTNNGWKYGVSLDENMKTHPLIRPFKTLTEKEKEIYRWPARESLKTMLAMGWSLERTK EGGEAIIHQRENEKLRSISQSSQGNGYTPAPLDLSNVVLSRELQGMVEVMAENYHNIWAK KKKMELESKGGGSHPLLVPYDTLTAKEKSRDREKAQELFKFLQVNGIIISRGLNDMELDA SSMEKRFAFKFLKKILKYVDSAQEFIAHLEAIVTSGKTEKSPHDQEIKFFAKVLLPLVDQ YFTNHCLYFLSSPTKTLSSSGYASNKEKEMVASLFCKLAALVRHRISLFGSDSATMVNCL HILAQSLDTRTVMKSGSELVKAGLRAFFENAAEDLEKTSENLKLGKFTHSRTQIKGVSQN INYTSVALLPILTSIFEHISQYHFGIDLLLGDVQVSCYRILSSLYSLGTGKNIYVERQRP ALGECLASLAAAIPVAFLEPSLNHYNPLSVFNTKSARERAILGMPDTVEEMCPEIPQLDG LIKEINDLAESGARYTEMPHVIEVILPMLCNYLSYWWERGSESIPQSAGPCCTMVTSEHL SIILGNILKIINNNLGIDEASWMKRIAVYAQPIISKARPDLLKSHFIPTLEKLKKKAIKI VMEEEQLRADSKTDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRANWLKKPDADSD ELFRMVAEVFILWCKSHNFKREEQNFVIQNEINNLAFLTGDTKSKMSKQIARRGMAMQVK SGGQDQERKKSKRRGDLYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKTRYSHKDT DDEVKEHLRNNLHLQEKSDDPAVKWQLNLYKDILKSDEPADPERNVERVQRISAALYHLE QVEQPLRSKKAVWHKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLHGYQNYWIETEEY SFEEKLVQDLATPPKKEEEEEEETEKKQPDPLHQIILYFSRSALTEKSKLEDDPLYIAYS AMMAKSCQEEEEEEEEKEKTFEEKEVEKQRTLYQQARLHDRGAAEMVLQMISASKGHPGP MVVETLKLGIAILNGGNTIVQQKMLDYLKEKKDAGFFQSLSGLMQSCSVLDLNAFERQNK AEGLGMVTEEGTLIVRERGEKVLQHDEFTRDLFRFLQLLCEGHNNDFQNYLRTQMGNTTT VNIIISTVDYLLRLQESISDFYWYYSGKDVIDESGQRNFSKALAVTKQIFNSLTEYIQGP CIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSAQIELLKELLDLLKDMVVMLLSLLE GNVVNGTIGKQMVDTLVESSSNVEMILKFFDMFLKLKDLTNSDAFKEHDPDGKGIISKKE FQKSMEAQKQYTQSETEFLLSCAEADENDMFNYIDFVERFHEPAKDIGFNVAVLLTNLSE HMPNDSRLQSLLEPAESVLNYFEPYLGRIEIMGGAKKIERVYFEISESSRMQWEKPQVKE SKRQFIFDVVNEGGEQEKMELFVNFCEDTIFEMQLASQISETDSSERPEEEEEAEPCHVV DIGGDEEEEKSLESASAFAMACAAVKKNVANFFRMVTVKSLRKQYRKVRKMTVKEMVKVF FSFFWILFVGVFQLFFTIVWGIFQLLWSTVFGGGLVEGAKNIKVTKILGDMPDPTQFGIH DDVMEAEKAESVEHGIRAELVQLVKGEKGEADIIADIFGIQTKKEGGSKHAHDAGLGDIA EILGTDIQSSLENTVRKKKGLQICEIAKEAETERKAEAEKADMEDGEKQDKAKEVQSEQL EEGKMKKKKRRHGQKIEKPEAVMANFFKALEIYQIKMLHCLARNFYNLRFLALFVAFAIN FILLFYKVTEEPLDEVEEDSNLWNSFDEEEEEEGMVFFVLQESTGYMAPALRALAVIHTI VSFVCVIGYYCLKVPLVVFKREKEVARKLEFDGLYITEQPSEDDIKGQWDRLVINTPSFP NNYWDKFVKRKVINKYGDLYGAERIAELLGLDKSALDFSPLEESEPEEASLVSWLSSIDT KYHIWKLGVVFTDNSFLYLAWYTTMSILGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHN GKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRA GGGIGDEIEDPAGDPYEMYRIVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVRED METKCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESFVWKM YQERCWDFFPAGDCFRKQYEDQLG NT seq 14655 nt NT seq  +upstreamnt  +downstreamnt atggctgaagggggtgaaggaggggaagatgaaatacagttcctacgaactgatgacgaa gtagtacttcagtgtgtcgccagcattcacaaagaacaaaggaagttttgcttggcagct gagggacttgggaatcgcctgtgctttttggaaccaacatcagaagctaaatatgttcct ccagatctttgcatctgtaattttgtccttgaacagtccctatctgtcagagcccttcaa gaaatgctggccaacacagcggagaatgctagtgaaggggcagctcaaggggctggtcac agaaccctgctctatggccatgctatactacttcgacattcgtttagtgaaatgtatttg acatgtttaacgtcatcaagatcccagacggataagcttgcatttgatgtgggactacga gaaaatgcagcaggtgaggcatgctggtggaccatacatccagcttctaaacaaaggtcg gaaggagaaaaagttcgaataggtgatgatcttatcctggtcagcgtgtcctctgaaaga tacctgcatctctccatgtcaaatggaagtattcaggtggatgcctcctttatgcagacg ctgtggaatgtacatcctacatgctcaggaagcagtattacagaaggttatcttcttggt gggcatgtagtacgtttcttccatggccatgatgagtgtttaacaattccatctacagat cagaatgattcacagcacaagaaagtgctttatgaaactggaggagctggtgttcgagca aggtctttgtggggagtagaaccgcttcgaataagctggagtggaagtaacatcagatgg ggacagcctttccgtcttcgacatattacaacaggaaagtacttggctctgaatgaagat gaagggcttgcaatgttagacagagaaaagtccgatacgacatctactgccttttgtttt agagcatcaaaggagctaaaagaaaagcaggattctagtcttaagcgtgacatggatgga atgggagtcccggaaataaagtatggtgattcagtctgctttgtccaacacgtggccagt gccttgtggttgacttacaaagcacaagatgctaaatcagcacgtttaggtcccttgaaa agaaaggttatactgcaccaagaaggccatatggatgatggtctaaccttacaaagatgt caacatgaggaatcccaggctgctcgaatcattcgcaacactacaagcttattcagccag tttataagtggaaacaacagaacactatcgcccactgccctgcctgttgaggagatggct cagactctgcaagacctaattacttacttccagcttcccgaagaagacctggaacatgaa gataagcaaagcaagcttcggtcactcaaaaacagacaaaatctattcaaagaagaggga atgctggcattagttttgaattgtattgatcgcttaaatgactacaacagtgcagctcat tttgctggaattgcaagagaagaacacggtacagcatggaaagaaattttgaatctcctt tataaattgttagctgctctcattcgtggcaacagaaacaattgtactcagttttccaga aaccttgactggctaataagtaaattggacagattagaatcttcctcaggtattttggaa gtgttgcactgcatcttaattgaaagcccagaagctttaaatgtaatagcagaggagcac atcaaatctattatttcattattggataaacatgggcgcaattacaaggttcttgatgtg ctttgttctctctgtgtttgtaatggagttgcagttcgtgccaatcaaaatttgatctgt gacaatctactgcctagaagagacttactcttgcaaacacgtttgattaatgatgtgaca agcataaggccaaatatatttttgggtgttgctgagggctctgcacaatacaagaagtgg tactttgagttaataattgatcaggttgatccattcttgacggcagaacctacccattta cgagttggatgggcctctacttcaggttatgccccctatcctggaggtggggaaggatgg ggaggcaatggagttggtgatgacctgtactcttatggttttgatggccttcatctctgg tctggccgagtacccagagctgtagcatctgtcaatcagcatttattagcatctgatgat gtggttagctgctgcttggatttgggtgtacccagcatttcattccgcattaatggacaa ccagtccaaggaatgtttgagaacttcagtacagaagggtttttcttccctgttgtaagc ttatcagcaggtgtaaaagttcgcttcttattgggcggacgacatggagagtttaaattt ctgccacctgctggctatgctccctgttatgaagcattgcttccgaaagagaagatgaaa ctggaaccagtgaaagaatataagagagattctgatggagtgagggattttctgggaaca acacaattcctttcccaagcttcctttattccttgtccaatagacaccagtcaggttgct cttccttttcatcttgaaaagatcagggacaaactagctgaaaatatccatgagctgtgg ggaatgaataaaatagaactgggctggacatatggaaagatacgggatgataataaaagg catcatccttgtcttgtggaattctcaaaattgcctgagacagagaagaattataatcta caaatgtcaactgaaaccctcaaaacccttttggcccttgggtgtcacattgttcacgct catccagcagctgaggaagatctgaaaagagttaaacttcctaaaaattacatgatgtca aatggatataaacctgcccctcttgatctttctgaagtgaaattgttaccttcacaagaa tttctagttgataaactagcagaaaatgcacataatgtctgggcaaaagacagaataaag caaggatggacctatggcattcagcaggatcttaagaacaaacgtaatcctcggctagtg ccatatgcattactagatgaacgtactaaaaaatcaaacagagatagtctccgtgaagcc gttagaacatttgcaggctacggttatagtattgagccacctgaccaagagataactgac caaacagtggaaaaagtcagcgtcgacaagatacgatttttcagagcagaacggtcttac gcagtgaagtctggaaaatggtacttcgaatttgaagctgtgacaggtggagatatgcga gttggctgggccaggccaggctgtcgacctgacatagagttgggagctgatgatcaagca tttgtgtttgaaggaagcaaaggccagcgttggcatcaaggcagtggattctttggacga agctggcaaccaggagacgtggttggttgtatgataaacttggatgacaaatcaatcatc tttactctcaatggagagttgcttataactagtaaaggttcagaacttgcgtttgctgac tttggaatagaaagtggttttgttccaatttgtgcactgggcctatctcagattggtcgt atgaaccttggaatggatgccagtacattcaagtattacaccatgtgtggccttcaagaa ggttttgaaccatttgctgtcaacatgaaccgagatgttgctatgtggtttagtaaacgc ttaccaacatttgtcaatgtgccaaaaaatcatcctcacattgagatatgtagaattgat ggaaacattgagagtccacctcggttaaaagttactcacaaaacatttgggacacagaac agcaattcagacatgatatattgtcgtttgagtatgcccatcgagttccactcatcattc aactttggcatgggtgtggaaaatgcctcatctgatgttttccaaaaaagaaagcacagc caagaaatcatagcttcgtctagtacatatttttattcactacggatatttgctggccaa gacccatcctctgtctgggttggctgggtaacaccagattatcatttttacagtgagaat tttgacctgaataaaaattgtacagtgacagttactttaggtgatgagagaggcagggtt catgaaagtgtgaagcgcagcaattgctatatggtttggggaggagatgtaattgctaat tcccagagatcaggtcgcagtaatgttgacttagaaattggatgctttgttgacctgact actggaatgttgtcattcacagccaatggaaaagagcttggcacttgttatcaggttgaa ccaaacacaaagctttttccagcagcttttgtacggcctacaagcactaacttgatacag tttgaacttggtaaattaaagaataccatgcccttatcagcagcaatttttaaaagtgaa gaaagaaatcctgttcctcagtgtccccctcgccttgatgtgcaaacaattacacctgtt ttatggagcaggatgccaaacagttttctaaaagtagaaaccgagcgtgtcagtgaacgc catggctgggttgtacagtgtttggaacctctgcagatgatggcacttcatatcccagaa gaaaacagatgcgttgatattttggaactatgtgaacaagaagatttgatgaagttccac taccacactttaaaactctatagctcagttagtgctctaggtaacactagagttgcttat gcactttgtagccatgtcgacatatctcagctgttttatacaatagataatcagtattta cctggactcctgcgttctggattctacgacttgctcattagtattcatttggagcacacc aagcaagccaaactcatgatgaacaatgaatttatcattcctgttacagatgaaactcga actattaagttatatcctgatgaaaaaaagaagcatggtttacctggagtagggcttagc acttgtctgaaaccgggctttagttttactactccatgctttattgtgaccagtgaagaa catcagacatccagcccagagataccccttgatatacttaaatccaaggccataagtatg ctaacagatgcagtacagtgtagtggtactcatatacgagaccctgttggaggacaggtt gcattccagtttgttcctgttcttaaactgatagcaacattgctcataatggaggttttt gatgatgatgatgtgaagcaggtgttactcctcattgatcccactgtgtttggagatcac aaggaagaaacagaggagaggacagagaaggaagaagttacacaagttgaagaaaaagct gtagaagctggggagaaagcaataaaagaaacgaaagctcctgcgaagggcttattgcac acaagattaccagagtctgttaagcttcagatgtgtcatttactcaattatttctgtgac tgtgaactaaaacatagagtggaagcaatagtatcatttgcagaccgttatgtatcgaaa ctgcaatataatcagaaatacagatacaatgaactcatgcaagccttgaacatgtctgct gctttgactgccaagaagactaaagaatttcgatctcctcctcaagaacagattaacatg ttactgaattttcaactgggagaggattgtccctgtccagaggagattcgggatgaatta tatgaatttcatgatgatcttctaatccactgtggtattccactagaagaggaggaagaa gaagaggaagattcctcctttactggcaaactccgttcactagtgtataaaatcaaaggt ccacccagagcagaaaaagtagaacctaaggaggaggaagagaaatctcctactacgctg aaagaacttatatcccagactatggtgcgctggtcgcaggaagatgagatccaagatcca gaattagttcggattatgtacaccctccttcgtaggcaatatgacagtattggcgagcta ctgcaagctctgaggaaagcatacactattagtgctacctctgtgaaggataccattaat ctgcttgcggcactgggccagattcgctcacttctcagtgtcaggatgggaaaagaggag gaattgctaatgattaatggattaggggctataatgaacaacaaagtgttttatcagcat cctaacttaatgagagttttgggtatgcatgagactgttatggatgtcatggtgaatgta cttggcggagataaatctcagcacatcacttttcctaagatggtggcaagctgttgtcga ttcctgtgctacttctgcagaattagtcgtcaaaaccaaaaggccatgtttgagcatctt agttacttactggaaaacagcagcgttggactggcatttccttcaatgagaggttcaaca ccactagatgttgcagcggcctctgtgatggacaacaatgagcttgcactagcactggaa gagccagatcttgataaggttgttacctacctggcgggttgtggcctgcagagttgtcca gtattgctggctaaaggatatccagacattgggtggaatccaatagagggtgaacgttac ctgtcatttttaagatttgtggtttttgttaacagtgaaagtgtcgaggaaaatgcaagt gttgttgtcaagcttcttattcgaaggccggagtgctttggaccagaccttaggggagaa ggaggaaatggtttgctggcagctatgcaggaagctatcagaatctcagagaatcctgct cgtgaccttccatcccaggcatataaaagagaaagtgatgatgaggaagaggaggaagag gagattgtgcatatgggcaatgcaatcatgtcattttactcagctctcatagatttactt ggacgctgtgcaccagaaatgcatcttattcaaagtggaaaaggggaagctattcgaatc aggtcaatccttcgatctctagtgccaactgaagatttggttgggattataagtatacca ctaaagctgtcaacagttaacaaagatggcacagtaaatgagccagacatgtctgcaaat ttctgtcctgatcataaagcacccatggtactcttcttggaccgtgtctatggtattaag gaccaaagcttcctccttcacctactggaagtcggatttttaccagatttaagagcctct gcctctttggatacagtttctctaagtaccacagaggcagctctcgcactaaatagatat atttgctcagctgtgtttccattactcaaaagatgtgctcccctcttttctggaacagag catcacgcctctctggttgactccatgcttcacacaatatataggttatccaagggacgt tcccttacaaaagcacaaagagacactattgaagaatgcctgcttgctatttgccaccac ttacgtccctctatgctacaacagttgttgagaaggctagtttttgatgtgcccttactc aatgaatactgtaaaatgcctctcaagcttctgacaaatcactatgagcagtgctggaaa tattattgtctgccttcaggaatgggaagctatggaattgcagcagaagaagaattacat ttaactgagaagcttttctggggtatatttgattccttgtctcataagttcctatctctc ctgcagaagtatgatccagagctctttcgaatggctttaccttgtctaagtgctatagct ggtgccttgccccctgattatttagataccagaattacgtcaactttggaaaagcagact tcattggatccggaaggaaattttgatcccaaacctgtcagcacagcacaccttgtactt cctgaaaagttggagtatattgtcagcaagtatgctgaacactcccatgataagtgggcc tttgataagactaataatgggtggaaatacggtgtttcactggatgaaaatatgaagact caccctttaataagacctttcaaaactttaactgaaaaggaaaaggaaatttatcgttgg cctgccagggaatcactgaagaccatgttggccatgggatggagcctagaaaggaccaag gaaggaggagaagcaataatacatcaacgtgaaaatgaaaagctccgcagcatatctcag tctagccagggaaatgggtataccccagcgccacttgatctttctaatgtagtgctttct agggagcttcagggaatggttgaggtaatggcagaaaactaccataatatatgggcaaag aagaagaaaatggagttggaaagcaaaggtggaggtagtcatcctttattggtaccttat gacacattgacagccaaagagaaatcacgggaccgtgaaaaggcacaagaactgtttaaa ttccttcaagtcaatggtataatcatatctcggggtctgaatgatatggagttggatgct tcatccatggaaaagaggtttgcctttaagtttctgaagaaaattttgaaatatgtcgat tctgctcaagagtttattgcacatttggaagccattgtaaccagtggaaaaactgaaaaa tctccgcatgaccaagaaataaaattctttgccaaagttcttttacctttagttgatcaa tactttacaaatcattgcctgtacttcctgtcttctccaacaaaaacactcagtagcagc ggatatgcatcaaataaggaaaaggaaatggtagcaagcctgttctgcaaactagctgct cttgttagacataggatctcactttttggcagtgattcagctacaatggtgaactgcctg cacatcttagctcagtctcttgacacacgaaccgttatgaaatcaggatctgagcttgtt aaagctggattgcgtgccttttttgaaaatgcagctgaagacctggaaaaaacttcagaa aatcttaaacttggaaaatttacccattcacgaacacaaattaagggcgtttcacagaat atcaattatacttcagtagcattgttaccgatcttgacatcaatttttgaacatatttca caatatcattttggaattgatttacttttgggtgatgtacaagtctcatgttacagaatt ctttctagcctctattcccttggaactgggaagaacatctatgttgaaaggcagcgtcct gcacttggtgagtgcttagcatctcttgcagcagccattccagtagcatttcttgaacct tctctcaaccattacaacccattgtctgtcttcaacacaaaaagtgcaagagaaagagca attttaggtatgcctgatacagtagaagagatgtgtccagagatccctcagttggatgga ctaataaaggaaattaatgatttagcagaatctggagcaaggtatactgaaatgcctcat gtaattgaggttatcttacccatgttatgcaactatttatcctactggtgggaaagagga tctgagagcattcctcaaagcgctgggccttgctgtacaatggtaacatctgaacatctg agcatcattcttggaaacattctgaaaataattaacaacaatctgggaatagatgaagca tcttggatgaaaagaattgcagtttatgctcaacccatcatcagcaaagccaggcctgat ctgctcaaaagtcactttattccgacactggagaaactgaagaagaaagctataaagatc gtgatggaagaggagcaactgagagcagatagtaaaactgacacccaagaagctgagcta ctcattctcgatgagtttgcagttctttgcagagacctttatgccttctatccaatgttg atacgttatgtagacaacaatagagcaaattggctaaagaaaccagatgcagactctgat gaactctttcgaatggtagctgaagtttttatcctgtggtgtaaatcacacaatttcaaa agagaagaacaaaattttgtgattcagaatgaaatcaacaatttggcatttttaacggga gacaccaagagcaagatgtctaaacagattgctcggaggggaatggccatgcaagtaaag tccggaggacaagatcaagaaagaaagaaatcaaaacgtagaggggatttgtactccata caaacatccttgattgtagctgcacttaaaaagatgcttcctattggtctgaatatgtgt actcctggagatcaagagctcatctctttggctaagactagatacagccataaagacacc gatgatgaagtcaaagaacatttacgtaacaacctacatttgcaggaaaagtctgatgat ccagctgtgaaatggcagttaaatctgtacaaagacattttgaagagcgatgaacctgct gaccctgagagaaatgtggaacgcgtgcagaggatatcagctgctctgtatcatctggaa caggttgaacaaccactgagatcaaagaaagctgtgtggcacaaacttctatcaaaacaa cgcaaaagagctgttgttgcatgtttcagaatggcaccattatacaacttgccaaggcac cgttctattaacctcttcctccatggctatcagaactattggatagaaacagaggaatat tcatttgaggagaaactagttcaggatttggctacacctccaaaaaaagaagaagaagaa gaggaagagactgagaaaaaacagcctgatccacttcatcagattatcctctatttcagt cgcagtgctctcacagagaaaagcaaattagaagatgatcctttatatattgcctattcc gccatgatggcaaagagctgccaggaagaagaagaggaagaagaagaaaaagaaaagaca tttgaggagaaagaagtggaaaaacagagaactctgtatcagcaagctcgcttacatgat cgtggagctgctgagatggtccttcagatgattagtgcaagcaaaggtcatccgggaccc atggttgttgagacactaaaactcggtattgctattctaaatggtggaaataccatagtt caacagaaaatgctagactacctgaaggagaaaaaggatgctggattttttcaaagtctc tctggcttgatgcagtcctgcagtgttcttgacttgaacgcctttgagagacaaaacaaa gccgaaggtctgggaatggttactgaagaagggactctcatcgttcgtgagcgtggtgaa aaagtattgcaacatgatgaatttactcgagatctctttagatttttacaactgctctgt gaagggcataacaatgattttcaaaattatctgcggactcagatgggcaacaccacaaca gtgaacattatcattagtacagttgactatcttttgcgtcttcaggaatcaatcagtgac ttctattggtactattcaggaaaggatgtcattgatgaatcaggacaacgtaacttctct aaagctttagctgtcaccaaacaaatattcaattcccttacagagtatatccagggccct tgcataggcaatcaacagagtctggctcacagtaggctgtgggatgcggttgttggcttt cttcatgtctttgccaatatgcagatgaaactctcacaggactctgctcagattgaattg cttaaagaactgctagatctgctaaaggatatggtagtgatgctcttgtcactgctcgaa ggtaacgtcgtaaatggaactatcggaaaacagatggtagacacgcttgtggaatcatct agcaatgtagaaatgattttgaagttttttgacatgttcctcaagttaaaggatctgact aactcagatgctttcaaagagcatgacccagatggtaaaggcatcatttcaaagaaggaa ttccagaaatcgatggaggctcaaaaacaatatacacagtcagagactgaatttctgctg tcctgtgcagaagctgatgaaaatgacatgtttaactatattgattttgtggaaagattc catgaaccagccaaagacattggatttaatgtagcagtattgctaacaaacctttcagaa cacatgcctaatgattcacgccttcagagcttacttgaaccagcagaaagtgttcttaat tactttgaaccgtaccttggccgtattgaaataatgggtggagccaagaaaatagaaaga gtctattttgaaatcagtgaatccagtagaatgcagtgggagaagccacaggtgaaggaa tccaaaagacagttcatatttgatgtagtaaatgaaggtggagagcaagaaaaaatggaa cttttcgtgaatttctgtgaagacacgatctttgaaatgcagttagcatcccagatctct gaaacggattcatctgagaggcctgaggaagaggaagaggcagagccttgtcatgtagtg gatatcggaggtgatgaggaagaagaaaagtccctggaatctgcttcagcttttgctatg gcctgtgctgctgtgaagaagaatgttgccaacttttttagaatggtcactgtgaagagt ctgaggaaacaatacaggaaagttagaaagatgacagtaaaagagatggtgaaagtgttt ttctcctttttctggattctgtttgtaggggtattccaactgttctttactatagtgtgg ggaattttccagcttctttggagcactgtatttgggggtggcctggttgaaggagccaaa aacattaaagttactaaaatactaggggacatgcctgacccaacacagtttggaatccat gatgatgttatggaagcagaaaaagctgaaagtgttgagcatggcataagagctgaactt gtgcagcttgtgaagggtgaaaagggagaagctgacatcattgcagacatttttggcatt caaacaaaaaaagaaggtggctcaaaacatgctcatgatgctggactcggagatattgca gaaatccttggtacagatatccagtcatctttggaaaacacagttcgtaaaaagaaagga ttacagatatgtgaaattgcaaaagaagctgaaacagaaagaaaagcagaagctgagaag gctgacatggaagatggtgaaaaacaagataaagcaaaggaagtgcaatctgagcagcta gaagagggaaaaatgaagaaaaagaagcgaaggcatggacaaaaaattgagaaaccagag gcagttatggctaacttcttcaaagctttggaaatttaccaaataaaaatgcttcactgc ttggcaagaaatttttataacttaaggtttctggctctatttgttgcatttgccatcaac tttattcttctattttacaaggtgacagaagagccacttgatgaagtagaggaagactct aacctctggaactctttcgatgaagaggaagaggaagagggcatggtattttttgtttta caagaaagtacaggttacatggcacctgctctcagagcactggcagttattcatactatc gtctcctttgtctgtgtgattggctactactgcttaaaggtccctctggttgtattcaag agagaaaaggaggtagctagaaagctggaatttgatggactatacataactgaacagcca tctgaagatgatattaaaggacagtgggatcgcctggttataaatactccgtcttttcct aacaattactgggacaaatttgtaaaacgaaaggttattaataagtatggagacttatat ggagcagaacgcatagcagaacttttgggtttggacaaaagtgcccttgattttagtcca ctggaagagagtgaaccagaagaggcatctcttgtatcatggttaagctctattgataca aaataccacatttggaagctcggagttgttttcactgataattcgtttttatacttagct tggtacacaactatgtctatccttgggcactacaacaacttcttctttgctgctcatctg ctggatattgctatgggtttcaaaacattgcgaaccattttgtcttcggtcactcacaat ggtaaacagcttgtgcttactgtaggactccttgctgtagtagtgtatctttacactgtc gtggcattcaacttcttccgcaaattctacaacaaaagtgaagatgaagatgaaccagac atgaaatgtgatgacatgatgacgtgttacctgttccacatgtatgtgggagtaagagct ggtggtggcattggagatgaaattgaagatcctgctggagacccttatgaaatgtatcga attgtttttgacatcacatttttcttctttgtcattgttatcctactggccattattcaa ggtctaattattgatgcttttggtgaattaagagaccagcaagaacaagtgagagaagat atggagaccaaatgttttatttgtggaatcggcaatgactattttgacacaaccccacat ggctttgagacacatactttgcaagaacacaacttggcaaactatttgttctttctgatg tatctcattaacaaggatgaaaccgaacatactggccaggagtcatttgtatggaagatg taccaagaaagatgctgggatttcttcccagcaggggactgcttccggaaacagtacgag gatcaacttggctaa

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