Charadrius vociferus (killdeer): 104288222 Help Entry 104288222         CDS       T08577                                  Symbol RYR3 Name (RefSeq) ryanodine receptor 3   KO K04963   ryanodine receptor 3 Organism cvf  Charadrius vociferus (killdeer) Pathway cvf04020   Calcium signaling pathway cvf04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:cvf00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     104288222 (RYR3)    04020 Calcium signaling pathway     104288222 (RYR3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:cvf04040]     104288222 (RYR3) Ion channels [BR:cvf04040]  Voltage-gated cation channels   Ryanodine receptor    104288222 (RYR3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR MIR SPRY Ins145_P3_rec RIH_assoc RR_TM4-6 EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_8 TBK1_ULD Motif Other DBs NCBI-GeneID:  104288222 NCBI-ProteinID:  XP_009885299 LinkDB All DBs Position Unknown AA seq 4358 aa AA seqDB search MGIPQPISVFDHAYRRGMERERQDLGKGDDEVVLQCVASIHKEQRKFCLAAEGLGNRLCF LEPTSEAKYVPPDLCICNFVLEQSLSVRALQEMLANTGDNASEGAAQGGGHRTLLYGHAI LLRHSFSEMYLTCLTSSRSQTDKLAFDVGLRENAAGEACWWTIHPASKQRSEGEKVRIGD DLILVSVSSERYLHLSMSNGSIQVDASFMQTLWNVHPTCSGSNITEGYLLGGHVVRFFHG HDECLTIPSTDQNDSQHKKVLYETGGAGVRARSLWRVEPLRISWSGSNIRWGQPFRLRHI TTGRYLALNEDEGLAMLDREKSDTTSTAFCFRASKELKEKQDSSLKRDIDGMGVPEIKYG DSICFVQHVASALWLTYKAQDAKSARLGPLKRKVILHQEGHMDDGLTLQRCQHEESQAAR IIRNTTSLFSQFTSGNNRTLSPTALPVEEMAQTLQDLITYFQLPEEDLEHEDKQSKLRSL KNRQNLFKEEGMLALVLNCIDRLNDYNTAAHFAGISREEHGTAWKEILNLLYKLLAALIR GNRNNCTQFSSNLDWLISKLDRLESSSGILEVLHCILIESPEALNIIAEEHIKSIISLLD KHGRNYKVLDVLCSLCVCNGVAVRANQNLICDNLLPRRDLLLQTRLINDVTSIRPNIFLG VAEGSAQYKKWYFELIIDQVDPFLTAEPTHLRVGWASTSGYAPYPGGGEGWGGNGVGDDL YSYGFDGLHLWSGRVPRAVASVNQHLLSSDDVVSCCLDLGVPSISFRINGQPVQGMFENF STEGFFFPVVSLSAGVKVRFLLGGRHGEFKFLPPAGYAPCYEALLPKEKMKLEPVKEYKR DFDGVRDLLGTTQFLSQASFIPCPIDTSQIALPFHLEKIRDKLAENIHELWGMNKIELGW TYGKIRDDNKRHHPCLVEFSKLPETEKNYNLQMSTETLKTLLALGCHIVHAHPAAEEDLK KVKLPKNYMMSNGYKPAPLDLSEVKLLPSQEFLVDKLAENAHNVWAKDRIKQGWTYGIQQ DLKNKRNPRLVPYALLDERTKKSNRDSLREAVRTFAGYGYSIEPPDQEIADQTVEKVSID KIRFFRVEQSYAVKSGKWYFEFEAVTGGDMRVGWARPGCRPDIELGADDQAFVFEGSKGQ RWHQGSGFFGRSWQPGDVVGCMINLDDKSIIFTLNGELLITSKGSELAFADFGIESGFVP ICALGLSQIGRMNLGMDASTFKYYTMCGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPK NHPHIEIWRIDGTIESPPRLKVTHKTFGTQNSNSDMIYCRLSMPIEFRSSFNFGMGVENA SSDVFQKRKHSQEIAAPSTTYFYSLRIFAGQDPSFVWVGWVTPDYHFYSENFDLNKNCTV TVTLGDERGRVHESVKRSNCYMVWGGDVIANSQRSGRSNVDLEIGCFVDLATGMLSFTAN GKELGTCYQVEPNTKLFPATFVQPTSTNLVQFELGKLKNTMPLSAAIFKSEERNPVPQCP PRLDVQTITPVLWSRMPNSFLKVETERVSERHGWVVQCLEPLQMMALHIPEENRCVDILE LCEQEDLMKFHYHTLKLYSSVSALGNTRVAYALCSHVDISQLFYTIDNQYLPGLLRSGFY DLLISIHLEHAKQAKLMMNNEFIIPVTDETRTIKLYPDETKKHGLPGVGLSTCLKPSFNF SSPCFIMTSEERQTSSPEIPLDTLKSKAISMLTEAVQCSGTHIRDPVGGQVAFQFVPVLK LIATLLIMGVFDDDDVKQVLLLIDPNVFGDHKEETEERTEKEEVTQVEEKAVEAGEKAIK ETKAPAKGLLQTRLPESVKLQMCHLLNYFCDCELQHRVEAIVSFADRYVSKLQYNQKYRY NELMQALNMSAALTAKKTKEFRSPPQEQINMLLNFQLGEDCPCPEEIRDELYEFHDDLLI HCGIPLEEEEEEEEDSSLTGKLRSLMYKIKGPPKAEKVEPKEEEEKSPTTLKELISQTMV RWSQEDQIQDPELVRVMYTLLRRQYDSIGELLQALRKAYTISAASVKDTINLLAALGQIR SLLSVRMGKEEELLMINGLGDIMNNKVFYQHPNLMRVLGMHETVMDVMVNVLGGDKSQHI VFPKMVASCCRFLCYFCRISRQNQKAMFEHLSYLLENSSVGLAFPSMRGSTPLDVAAASV MDNNELALALEEPDLDKVVTYLAGCGLQSCPVLLAKGYPDIGWNPIEGERYLSFLRFAVF VNSESVEENASVVVKLLIRRPECFGPDLRGEGGNGLLAAMQEAIRISENPTRDLPSQAYK REGDDEEEEEEIVHMGNAIMSFYSALIDLLGRCAPEMHLIQSGKGEAIRIRSILRSLVPT EDLVGIISIPLKLSTVNKDGTVNEPDMSASFCPDHKAPMVLFLDRVYGIKDQSFLLHLLE VGFLPDLRASASLDTVSLSTTEAALALNRYICSAVFPLLKRCAPLFSGTEHHASLVDSML HTIYRLSKGRSLTKAQRDTIEECLLAICHHLRPSMLQQLLRRLVFDVPLLNEYCKMPLKL LTNHYEQCWKYYCLPSGMGSYGIAAEEELHLTEKLFWGIFDSLSHKKYDPELFRMALPCL SAIAGALPPDYLDTRSRSTLEKQTSVDPEGNFDPKPVSTANLVLPEKLEYIVSKYAEHSH DKWAFDKTNSGWKYGVSLDENTKTHPLIRPFKTLTEKEKEIYRWPARESLKTMLAMGWSL ERTKEGGEAVIHQRENEKLRSISQSSQGNGYIPAPLDLSNVVLSRELQGMVEVMAENYHN IWAKKKKIELESKGGGSHPLLVPYDTLTAKEKSRDREKAQELFKFLQVNGIIISRGLNDM ELDASSMEKRFAFKFLKKILKYVDSAQEFIAHLEAIVTSGKTEKSPHDQEIKFFAKVLLP LVDQYFTNHCLYFLSSPTKTLSSSGYASNKEKEMVASLFCKLAALVRHRISLFGSDSATM VNCLHILAQSLDTRTVMKSGSELVKAGLRAFFENAAEDLEKTSENLKLGKFTHSRTQIKG VSQNINYTTVALLPILTSIFEHISQYQFGIDLLLGDVQVSCYRILCSLYSLGTGKNIYVE RQRPALGECLASLAAAIPVAFLEPSLNHYNPLSVFNTKSARERAILGMPDTVEEMCPEIP QLDGLIKEINDLAESGARYTEMPHVIEVILPMLCNYLSYWWERGSESVPQSAGPCCTMIT SEHLSIILGNILKIINNNLGIDEASWMKRIAVYAQPIISKARPDLLKTHFIPTLEKLKKK AIKIVMEEEQLRADSKTDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRANWLKKPD ADSDELFRMVAEVFILWCKSHNFKREEQNFVIQNEINNLAFLTGDTKSKMSKAMQVKSGG QDQERKKSKRRGDLYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKTRYSHRDTDDE VKEHLRNNLHLQEKSDDPAVKWQLNLYKDILKSDEPTDPERNVERVQRISAALYHLEQVE QPLRSKKAVWHKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLHGYQNYWIETEEYSFE EKLVQDLATPPKKDEEEEEETEKKQPDPLHQIILYFSRSALTERSKLEDDPLYIAYSAMM AKSCQEEEEEEEEEKEKTFEEKEMEKQRTLYQQARLHDRGAAEMVLQMISASKGHTGPMV VETLKLGIAILNGGNSIVQQKMLDYLKEKKDAGFFQSLSGLMQSCSVLDLNAFERQNKAE GLGMVTEEGTLIVRERGEKVLQHDEFTRDLFRFLQLLCEGHNNDFQNYLRTQMGNTTTVN IIISTVDYLLRLQESISDFYWYYSGKDVIDESGQRNFSKALAVTKQIFNSLTEYIQGPCI GNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSAQIELLKELLDLLKDMVVMLLSLLEGN VVNGTIGKQMVDTLVESSSNVEMILKFFDMFLKLKDLTNSDAFKEHDPDGKGIISKKEFQ KSMEAQKQYIQSEIEFLLSCAEADENDMFNYIDFVERFHEPAKDIGFNVAVLLTNLSEHM PNDSRLQSLLEPAESVLNYFEPYLGRIEIMGGAKKIERVYFEISESSRMQWEKPQVKESK RQFIFDVVNEGGEQEKMELFVNFCEDTIFEMQLASQISETDSSERPEDEEEEEPCYVVDI GDDEEEKSLESASAFAMACVAVKKNVANFFKMVTVRNLRKQYRKVRKMTVKEMVKVFFSF FWILFVGMFQLFFTIVWGIFQILWSTVFGGGLVEGAKNIKVTKILGDMPDPTQFGIHDDV MEAEKADGAEHGIRAELVQFVKGEKGETDIISDIFGIHTKKEGGSKHGHDAGLGDIAEIL GTDIQSSLENTVRKKKGLQISEIAKEAERERKAEAEKA NT seq 13076 nt NT seq  +upstreamnt  +downstreamnt atgggtattccacaaccaatcagtgtgtttgaccatgcttacaggagagggatggaaaga gagagacaggacctgggaaaaggggatgacgaagtagtacttcagtgtgttgccagtatt cacaaagaacaaaggaagttttgcttggcagctgagggacttgggaatcgcctgtgcttt ttggaaccaacatcagaagctaaatatgttcccccggacctttgcatctgtaatttcgtc cttgaacagtccctgtctgtcagagcccttcaagaaatgctggccaacacaggggataat gctagtgaaggggcagctcaagggggtggtcacagaaccctgctgtatggccatgctata ctacttcgacattcgtttagtgaaatgtatttgacatgtttaacatcatcaagatctcag acggataaacttgcatttgatgtgggactacgagaaaatgcggcaggtgaggcatgctgg tggacaatacaccctgcttctaaacaaaggtcagaaggagaaaaagttcgaataggtgat gatcttatcctggtcagtgtgtcctctgaaagatacctgcatctctccatgtcaaatgga agtattcaggtggatgcctcctttatgcagacgctatggaatgtacatcctacatgctca ggaagcaatattacagaaggatatcttcttggtgggcatgtagtacgttttttccatgga catgatgagtgtttaacaattccatctacagatcagaatgattcacagcacaagaaagta ctttatgaaactggaggagctggtgttcgagcaaggtctttgtggagagtagaacccctt cgaataagctggagtggaagtaacatcagatggggacagcctttccgtcttcgacatatt acaacggggaggtacttggctctgaatgaagatgaaggacttgcaatgttagacagagaa aagtcagacacgacatctactgccttttgttttagagcatcaaaggagctaaaagagaag caggattctagtcttaaacgtgacattgatggaatgggagtcccagaaataaagtacggt gattcaatctgttttgtccaacatgtggccagtgccttatggttgacttacaaagcacaa gacgctaaatcagcacgcttaggtcccttgaaaagaaaggttatattacaccaagaaggc catatggatgatggtctaaccttacaaagatgtcagcatgaggaatcccaggctgctcga atcattcgcaacactacaagcttattcagccagtttacaagtggaaacaacagaacacta tcacccactgccctgcctgttgaggagatggctcagactctgcaagacctgattacttac ttccagcttcccgaagaagacctggaacatgaagataagcaaagcaagcttcggtcactc aaaaacagacaaaatctatttaaagaagagggaatgctggcactagttttgaattgtatt gatcgcttaaatgactacaacaccgcagctcattttgcaggaatttcaagagaagaacat ggtacagcatggaaagaaattttgaatctcctttacaaattgttagctgctctcattcgt ggtaacagaaacaattgtactcagttttccagtaacctcgattggctaataagtaaattg gacagattagaatcttcctcaggtattttggaagtgttgcactgcatcttgattgaaagc ccagaagctttaaatataatagctgaggagcatatcaaatccattatttcattgttggat aaacacgggcgcaattacaaggttctcgatgtgctttgctctctctgtgtctgtaatgga gttgcagttcgtgccaatcaaaatttgatctgtgacaacctactgcccagaagagactta ctcttgcaaacacgtttgattaatgatgtgacaagcataaggccaaacatatttttgggt gttgctgagggctctgcacagtacaagaagtggtactttgagttaataattgatcaggtt gatccattcttgacggcagaacccacccatttacgagttggatgggcctctacttcaggt tatgccccctatcccggaggtggagaaggatggggaggcaatggtgttggcgatgacttg tactcttacggttttgatggccttcatctgtggtctggtcgagtacccagagctgtagca tctgtcaatcagcatttattatcatctgatgatgtggttagctgctgcttggatttaggt gtacccagcatttcattccgcattaatggacagcctgtacaaggaatgtttgagaacttc agtacagaagggtttttctttcctgttgtaagcttatcagcaggtgtaaaagttcgtttc ttactgggtggacgtcatggagagtttaaatttctgcctcctgctggctatgctccctgt tatgaagcgttgcttccaaaagagaagatgaaactggaaccagtgaaagaatataagaga gattttgatggagtgagggatttgctgggtacaacacaattcctctcccaagcttccttt atcccttgtccgatagacaccagtcagattgctcttccttttcatcttgaaaagatcagg gacaaactagctgaaaatatccatgaactgtggggaatgaataaaatagaactgggctgg acatacggcaagatacgggatgataataaaaggcatcatccttgtcttgtggaattctca aaattgcctgagacagagaagaattataatcttcaaatgtcaactgaaaccctcaaaacc cttctagcccttggatgtcacattgttcatgctcatccggcagctgaggaagatcttaaa aaagtcaaacttcctaaaaattatatgatgtcaaacggatataaacctgcccctcttgat ctttctgaagtgaaattgttaccttctcaagaatttctagttgacaaactagcagaaaat gcacataatgtctgggcaaaagacagaataaagcaaggatggacctatggcattcagcag gatcttaagaacaaacgtaatcctcggctagtgccatatgcattattagatgaacgtact aaaaaatcaaacagagatagccttcgcgaagctgttagaacatttgcgggctatggttat agtattgagccacctgaccaagagatagctgaccaaacagtggaaaaagtcagcatcgac aagataagatttttcagagtagaacagtcttacgcagtgaagtctggaaagtggtacttt gaatttgaagctgtgacaggtggagatatgcgtgttggctgggccaggccaggctgtcga cctgacatagagttgggagctgatgaccaagcatttgtatttgaaggaagcaaaggccag cgttggcatcaaggcagtggattctttggacgaagctggcaaccaggagatgtggttggt tgtatgataaacttggatgacaaatcaattatctttactctgaatggagagttgcttata accagtaaaggttcagaacttgcgtttgctgactttggaatagaaagtggttttgttcca atttgtgcactgggtctatctcagattggtcgtatgaaccttggaatggatgccagtaca ttcaagtattacacaatgtgtggccttcaagaaggtttcgaaccttttgctgtcaacatg aaccgagatgttgctatgtggtttagtaaacgcttaccaacatttgtcaacgtgccaaaa aatcatcctcacattgagatatggagaattgatggaaccatcgagagtccacctcggcta aaagttactcacaaaacatttggcacacagaacagcaattcagacatgatatattgtcgt ttgagtatgcccattgagttccgctcatcattcaacttcggcatgggtgtggaaaatgct tcatctgatgttttccaaaaacgaaagcacagccaagaaattgctgctccttctacaaca tatttttattcactacggatatttgctggccaagacccatcctttgtctgggttggctgg gtaacaccagactatcatttttacagtgagaattttgacctaaataaaaattgtacagtg acagttactttaggtgatgagagaggcagggttcatgaaagtgtgaagcgcagcaattgc tatatggtgtggggaggagatgtaattgctaattcccagagatcaggtcgcagtaatgtt gatttagaaattggatgctttgttgacctggctactggaatgttgtcattcacagccaat ggaaaagagcttggcacttgttaccaggttgaaccaaatacaaagctttttccagcaact tttgtacagcctacgagcactaacttggttcagtttgaacttggtaaattaaagaatacc atgcctttatcagcagcaatttttaaaagtgaagaaagaaatcccgttcctcagtgtccc cctcgccttgatgtgcaaacaattacacctgttttatggagcaggatgccaaacagcttt ctaaaagtagaaactgagcgtgtcagtgaacggcatggctgggttgtgcagtgtttggaa cctctgcagatgatggcacttcatatcccggaagaaaacagatgtgttgatattttggaa ctctgtgaacaagaagatttgatgaagtttcactaccacactttaaaactctatagctca gttagtgctctaggtaacactagagttgcttatgcactttgtagccatgtggacatatct cagctattttatacaatagataatcaatacttacctggactcctgcgttctggattctat gacttgctcattagtattcatttggagcatgccaagcaagccaagctcatgatgaacaat gaatttatcattccagttacagatgaaactcgaactattaaattgtatcctgatgaaaca aagaagcatggtttacctggagtagggcttagcacttgtctgaaaccaagctttaatttt tctagtccatgctttattatgaccagtgaagaacgtcagacatccagcccagagatcccc cttgatacacttaaatccaaggccataagtatgctaacagaggcagtacagtgtagtggt actcatatacgagaccctgttggaggacaggttgcattccagtttgttcctgttcttaaa ctgatagcaacattgcttataatgggggtttttgatgatgatgatgtgaagcaggtgtta ctcctcattgatcccaacgtgtttggagatcacaaggaagaaacagaagagagaacagag aaggaagaagttacacaagtagaagaaaaagctgtggaagctggggagaaagcaataaaa gaaacgaaagctcctgcaaagggcttactgcagacaaggttaccagaatctgttaagctt cagatgtgtcatttactcaattatttctgtgactgtgagctacaacacagagtggaagca attgtatcgtttgcggaccgctatgtatcaaaattgcaatataatcagaaatacaggtac aatgaactcatgcaagccttgaacatgtctgctgctttgactgccaagaagactaaagaa tttcggtctccccctcaagaacagattaatatgttgctgaattttcaactgggagaggat tgtccttgtccagaggagattcgggatgagttatatgaatttcatgatgatcttctaatt cattgtggtattccactagaagaggaggaagaggaagaggaagattcctccttgactggc aaactccgttcattaatgtacaaaatcaaaggtccaccaaaagcagagaaagtagaacct aaggaggaagaagagaaatcccctactacactgaaagaactcatatcccagactatggtg cgctggtcccaagaagatcagattcaagatccagaattagttcgggttatgtacacgctc cttcgcaggcaatatgacagcattggtgagctactgcaagctctgcggaaagcatacact attagtgctgcctctgtgaaggataccattaatctgcttgcagcactgggccagattcgc tcacttctcagtgtcaggatgggaaaagaggaggaattgctaatgattaatggattaggg gatataatgaacaacaaagtgttttatcaacatcctaacttaatgagagtcttgggcatg catgagactgttatggatgtgatggtgaatgtgcttggaggagataaatctcagcacatc gtttttcctaagatggtggcaagctgttgtcgattcctgtgctacttctgtcgaattagt cgtcaaaaccaaaaggctatgtttgagcatcttagttacttattggaaaacagcagcgtt ggactggcttttccttcaatgagaggttcaacaccactagatgttgcagcagcctctgta atggacaacaatgagcttgcactagcattggaggagccagatctcgataaggttgtcacc tacctggcaggttgtggcctacagagttgtccagtattgctggctaaaggatatccagac attggatggaatccaatagagggtgaacgttacctgtcattcttaagatttgcagttttt gttaacagtgaaagcgttgaggaaaatgcaagcgttgttgtcaagctccttattcgacgg ccagagtgctttggaccagaccttaggggagaaggaggaaatggtttgctggcagctatg caggaagctatcaggatctcagagaatcctactcgtgaccttccctcccaggcgtataaa agagaaggtgatgatgaggaggaggaggaagagattgtgcacatgggcaatgcaatcatg tcattttattcagctctcatagatttacttggacgctgtgcaccagaaatgcatcttatt caaagtggaaaaggggaagctattcgaatcaggtcaatccttcgatctctagtgcctact gaagatttggttgggattataagtataccactaaagctgtcaacagttaacaaagatggc acagtaaatgagccagacatgtctgcaagtttctgtcctgatcataaagcacccatggta ctctttttggaccgtgtctatggtataaaggaccaaagcttcctccttcacctactggaa gtgggatttttaccagatttaagagcctctgcctctttggatacagtttccctgagcacc acagaggcagctctcgcactaaatagatatatttgctcagctgtgtttccattgctcaaa agatgtgctcccctcttttctggaacagagcatcatgcctctctggttgactccatgctt cacacaatatataggttatccaagggacgttcccttacaaaagcacaaagagacactatt gaagagtgcctgcttgctatttgccaccacttacgaccttctatgctacaacagctgttg agaaggctggtttttgatgtgcccctactcaatgaatactgtaaaatgcctctcaagctt ctgacaaatcactatgagcagtgctggaaatattattgtctgccttcaggaatgggaagc tatggaattgcggcagaagaagaattacatttaactgaaaaacttttctggggaatattt gattccttgtctcataagaagtatgatccagagctctttcgaatggctttgccttgtcta agtgctatagctggtgccttgccccctgattatttagatacacgaagtaggtcaactttg gaaaagcagacttcagtggatccagaagggaattttgatcccaaacctgtcagcacagca aaccttgtacttcctgaaaagttggagtatattgtcagcaagtatgctgaacattcccat gataaatgggcctttgataagactaatagtggatggaaatacggtgtttcactggatgaa aatacgaagactcacccattaataagacctttcaagactttaactgaaaaggaaaaggaa atttatcgttggcctgccagagaatcactgaaaaccatgttggccatgggatggagccta gaaaggaccaaggaaggaggagaagcagtaatacatcagcgtgaaaatgaaaagctccgc agcatatctcagtctagccagggaaatgggtatatcccagcgccgcttgatctctctaat gtggtgctttctagggagcttcagggaatggttgaagtaatggcagaaaactaccataat atatgggccaaaaagaagaaaattgagttggaaagcaaaggtggaggtagtcatccttta ttggtaccttacgacaccttgacagccaaggagaaatcacgggaccgtgaaaaggcacaa gagctttttaaatttcttcaagtcaatggtataatcatatctcggggtctgaatgacatg gagttggatgcttcatcaatggaaaagaggtttgcctttaagtttctgaagaaaatctta aaatatgttgattctgctcaagagtttattgcacatttggaagccattgtaaccagtgga aaaactgaaaaatctccacatgaccaagaaataaaattctttgccaaagttcttttacca ttagttgatcagtactttacaaatcactgcctctacttcctgtcttctccaacaaaaaca ctcagtagcagtggatatgcatcaaataaggaaaaggaaatggtagcaagcctgttctgc aaactagctgctcttgttagacataggatctcactttttggtagtgattcagctacaatg gtgaactgcctacacatcttagctcagtctcttgacacacgaactgttatgaaatcagga tctgagcttgttaaagctggattgcgtgccttttttgaaaatgcagctgaagacctggaa aaaacttcagaaaatcttaaacttggaaaatttacccattcacgaactcaaatcaagggt gtttcacaaaatatcaattatactacagtagcattgttaccaatcttgacatcaattttt gaacatatttcacaatatcagtttggaattgatttacttttgggtgatgtacaagtttca tgttacagaattctttgtagcctctattcccttgggaccgggaagaacatctatgttgaa aggcagcgtcctgcacttggtgagtgcttagcatctcttgcagcggccattccggtagca ttccttgaaccttctctcaaccattacaacccattgtctgtcttcaacacaaaaagtgca agagaaagagcaattttaggcatgcctgacacagtagaagagatgtgtccagagatccct cagttggatggactaataaaggaaattaatgatttagcagagtctggagcacggtatact gaaatgcctcatgtaattgaggttatcttacccatgctatgcaactatttatcctactgg tgggaaagagggtctgagagtgttcctcaaagtgctgggccttgctgtacaatgataaca tctgagcatctgagcatcattcttggaaacattctgaaaatcattaacaacaatctggga atagatgaagcatcttggatgaaaagaattgcagtttatgctcaacccatcatcagcaaa gccaggcctgatctgctcaaaactcactttattccaacactggagaaattgaagaagaag gctataaagatcgtgatggaagaggagcaacttagagcagatagtaagactgacacccaa gaagctgagctgctcattctcgatgagtttgctgttctttgtagagacctttacgccttc tatccaatgttgatacgttatgtagataacaacagagccaattggctaaagaaaccagat gcagattctgatgaactctttcgaatggtagctgaagtttttatcctgtggtgtaaatca cataatttcaaaagagaagaacaaaattttgtgattcagaatgaaatcaacaatttggcg tttttaacaggagacaccaagagcaagatgtctaaagccatgcaagtaaagtctggagga caagatcaagagagaaagaaatcaaaacgtagaggggatttgtactccatacaaacatcc ttgattgtagcggcacttaaaaagatgcttcctattggtttgaatatgtgtactcctgga gatcaagagctcatctctttggccaagactagatatagccatagggacactgatgatgaa gtcaaagaacatttacgtaacaacttacatttgcaagaaaagtctgatgatccagctgta aaatggcagttaaatctgtacaaagacattttgaagagtgatgaacctactgaccctgag agaaatgtggaacgtgtgcagaggatatcagctgctctgtatcatctggaacaggttgaa caaccactgagatcgaagaaagctgtttggcacaaactcctgtcaaaacaacgcaaaagg gctgttgttgcatgtttcagaatggcaccgttatacaacctcccaaggcaccgttctatt aacctcttcctccatggctatcagaactattggatagaaacagaggaatattcatttgag gagaaactagttcaggatttggctacacctccaaaaaaagatgaagaggaagaggaagag accgagaaaaaacagcctgatccacttcatcagattatcctctatttcagtcgcagcgct ctcacagaaagaagcaaattagaagatgatcctttatatattgcctattccgccatgatg gcaaagagctgccaagaagaagaagaagaggaagaagaagaaaaagaaaagacatttgag gagaaagaaatggaaaaacagagaactctctatcagcaagctcgcttacatgatcgtgga gctgctgagatggtcctccagatgattagtgcaagcaaaggtcatacaggacccatggtt gttgaaacactgaaacttggtattgctattctaaatggtgggaattccatagttcaacag aaaatgctagactacctgaaagagaaaaaggatgctggattttttcaaagtctctctggc ttgatgcagtcctgcagtgttcttgacttgaatgcgtttgagagacaaaataaagcagaa ggcctgggaatggttactgaagaaggaactctcatcgttcgtgagcgtggtgaaaaagtg ttgcagcatgacgaatttactcgggacctatttagatttttacaactgctttgtgaaggg cataacaatgattttcaaaattacctacgtactcagatgggcaacaccacaacagtgaat attatcattagtacagttgactatctcttgcgtcttcaggaatcaatcagtgacttctat tggtactattcaggaaaggatgttattgatgaatcaggacaacgtaacttctctaaagct ttggctgtcaccaaacaaatattcaattcccttacagaatatatccagggcccttgcata ggtaatcaacagagtctggctcatagcaggctgtgggatgcagttgttggcttccttcat gtctttgccaatatgcagatgaaactttcacaggactctgctcagattgaattgcttaag gaactgctagatctcctgaaggatatggtagtgatgctcttgtcactgcttgaaggtaac gttgtaaatggaactattggaaaacaaatggtagacacgcttgtagaatcatctagcaat gtagaaatgattttgaagttctttgacatgttcctcaagttaaaagatctcactaactca gatgctttcaaagagcatgacccagatggtaaaggcatcatttcaaagaaggaattccag aaatcaatggaggctcaaaagcaatacatacagtcagagattgaattcctgctttcctgt gcagaagctgatgagaatgatatgtttaactatattgattttgtggaaaggttccatgag ccagccaaagacattggatttaacgtagcagtgttgcttacaaacctttcagaacacatg cctaatgattcacgccttcagagcttacttgaacctgcggaaagtgttctaaattacttt gaaccataccttggccgtattgaaataatgggtggagccaagaaaatagaaagagtttac tttgaaatcagtgaatccagtagaatgcagtgggagaagccacaggtgaaggaatccaaa aggcagttcatatttgatgttgtaaatgaaggtggagagcaagaaaaaatggaactcttc gtgaatttctgtgaagacacaatctttgaaatgcagttagcatcccagatctctgaaacg gattcatctgaaaggcctgaggacgaggaagaggaagagccttgttatgtagtggatatt ggagatgatgaggaagaaaagtccctggaatctgcttcagcttttgcaatggcctgtgtt gcagtgaagaagaatgttgccaacttttttaaaatggtcactgtgaggaacctaaggaaa caatacaggaaagttagaaagatgacagtaaaagaaatggtgaaagtgtttttctccttt ttctggatcctatttgtagggatgttccagctcttctttactatagtgtggggaattttc cagattctttggagcactgtctttgggggggggctggttgaaggagccaaaaacattaaa gttactaaaatattaggggacatgcctgacccaacgcagtttggaatccatgatgatgtt atggaagccgaaaaagctgacggtgctgagcatggcatcagagctgaacttgtgcagttt gtgaaaggtgaaaagggagaaactgacatcatctcagacatttttggtattcatacaaag aaagaaggtggctcaaaacatggtcatgatgctggacttggagatattgcagaaatcctt ggtactgatatccagtcatctttggaaaacacagttcgtaagaaaaaaggattacagata tctgaaattgcaaaagaagctgaaagagaaagaaaagcagaagctgagaaggctga

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