KEGG   DRUG: アトルバスタチンカルシウム水和物
エントリ  
D02258                      Drug                                   
一般名   
アトルバスタチンカルシウム水和物 (JP18);
アトルバスタチンカルシウム;
Atorvastatin calcium (USP);
Atorvastatin calcium hydrate (JP18);
Atorvastatin calcium trihydrate
商品名   
  後発品
米国の商品 
  後発品
ATORVASTATIN CALCIUM (A-S Medication Solutions), ATORVASTATIN CALCIUM (A-S Medication Solutions), ATORVASTATIN CALCIUM (A-S Medication Solutions), ATORVASTATIN CALCIUM (A-S Medication Solutions), ATORVASTATIN CALCIUM (A-S Medication Solutions), ATORVASTATIN CALCIUM (A-S Medication Solutions), ATORVASTATIN CALCIUM (A-S Medication Solutions), ATORVASTATIN CALCIUM (A-S Medication Solutions), ATORVASTATIN CALCIUM (A-S Medication Solutions), ATORVASTATIN CALCIUM (A-S Medication Solutions), ATORVASTATIN CALCIUM (A-S Medication Solutions), ATORVASTATIN CALCIUM (A-S Medication Solutions), ATORVASTATIN CALCIUM (A-S Medication Solutions), ATORVASTATIN CALCIUM (A-S Medication Solutions), ATORVASTATIN CALCIUM (A-S Medication Solutions), ATORVASTATIN CALCIUM (A-S Medication Solutions), ATORVASTATIN CALCIUM (A-S Medication Solutions), ATORVASTATIN CALCIUM (A-S Medication Solutions), ATORVASTATIN CALCIUM (A-S Medication Solutions), ATORVASTATIN CALCIUM (A-S Medication Solutions), ATORVASTATIN CALCIUM (A-S Medication Solutions), ATORVASTATIN CALCIUM (A-S Medication Solutions), ATORVASTATIN CALCIUM (A-S Medication Solutions), ATORVASTATIN CALCIUM (A-S Medication Solutions), ATORVASTATIN CALCIUM (A-S Medication Solutions), ATORVASTATIN CALCIUM (A-S Medication Solutions), ATORVASTATIN CALCIUM (Accord Healthcare), ATORVASTATIN CALCIUM (American Health Packaging), ATORVASTATIN CALCIUM (Aphena Pharma Solutions - Tennessee), ATORVASTATIN CALCIUM (Aphena Pharma Solutions - Tennessee), ATORVASTATIN CALCIUM (Aphena Pharma Solutions - Tennessee), ATORVASTATIN CALCIUM (Aphena Pharma Solutions - Tennessee), ATORVASTATIN CALCIUM (Aphena Pharma Solutions - Tennessee), ATORVASTATIN CALCIUM (Aphena Pharma Solutions - Tennessee), ATORVASTATIN CALCIUM (Aphena Pharma Solutions - Tennessee), ATORVASTATIN CALCIUM (Ascend Laboratories), ATORVASTATIN CALCIUM (AvPAK), ATORVASTATIN CALCIUM (Bryant Ranch Prepack), ATORVASTATIN CALCIUM (Bryant Ranch Prepack), ATORVASTATIN CALCIUM (Bryant Ranch Prepack), ATORVASTATIN CALCIUM (Bryant Ranch Prepack), ATORVASTATIN CALCIUM (Bryant Ranch Prepack), ATORVASTATIN CALCIUM (Bryant Ranch Prepack), ATORVASTATIN CALCIUM (Bryant Ranch Prepack), ATORVASTATIN CALCIUM (Bryant Ranch Prepack), ATORVASTATIN CALCIUM (Bryant Ranch Prepack), ATORVASTATIN CALCIUM (Bryant Ranch Prepack), ATORVASTATIN CALCIUM (Bryant Ranch Prepack), ATORVASTATIN CALCIUM (Bryant Ranch Prepack), ATORVASTATIN CALCIUM (Bryant Ranch Prepack), ATORVASTATIN CALCIUM (Bryant Ranch Prepack), ATORVASTATIN CALCIUM (Bryant Ranch Prepack), ATORVASTATIN CALCIUM (Bryant Ranch Prepack), ATORVASTATIN CALCIUM (Bryant Ranch Prepack), ATORVASTATIN CALCIUM (Bryant Ranch Prepack), ATORVASTATIN CALCIUM (Bryant Ranch Prepack), ATORVASTATIN CALCIUM (Bryant Ranch Prepack), ATORVASTATIN CALCIUM (Bryant Ranch Prepack), ATORVASTATIN CALCIUM (Bryant Ranch Prepack), ATORVASTATIN CALCIUM (Bryant Ranch Prepack), ATORVASTATIN CALCIUM (Cadila Healthcare Limited), ATORVASTATIN CALCIUM (Cardinal Health), ATORVASTATIN CALCIUM (Cipla USA Inc.,), ATORVASTATIN CALCIUM (DIRECT RX), ATORVASTATIN CALCIUM (DIRECT RX), ATORVASTATIN CALCIUM (Denton Pharma), ATORVASTATIN CALCIUM (Denton Pharma), ATORVASTATIN CALCIUM (Denton Pharma), ATORVASTATIN CALCIUM (Denton Pharma), ATORVASTATIN CALCIUM (Denton Pharma), ATORVASTATIN CALCIUM (Denton Pharma), ATORVASTATIN CALCIUM (Denton Pharma), ATORVASTATIN CALCIUM (Denton Pharma), ATORVASTATIN CALCIUM (Denton Pharma), ATORVASTATIN CALCIUM (Denton Pharma), ATORVASTATIN CALCIUM (DirectRX), ATORVASTATIN CALCIUM (DirectRX), ATORVASTATIN CALCIUM (DirectRx), ATORVASTATIN CALCIUM (Direct_Rx), ATORVASTATIN CALCIUM (Direct_Rx), ATORVASTATIN CALCIUM (Dr. Reddy's Laboratories Limited), ATORVASTATIN CALCIUM (Dr. Reddy's Laboratories Limited), ATORVASTATIN CALCIUM (Golden State Medical Supply), ATORVASTATIN CALCIUM (Greenstone LLC), ATORVASTATIN CALCIUM (Lannett Company), ATORVASTATIN CALCIUM (Lupin Pharmaceuticals), ATORVASTATIN CALCIUM (MSN LABORATORIES PRIVATE LIMITED), ATORVASTATIN CALCIUM (Mckesson Corporation DBA SKY Packaginng), ATORVASTATIN CALCIUM (Mckesson Corporation DBA SKY Packaginng), ATORVASTATIN CALCIUM (Micro Labs Limited), ATORVASTATIN CALCIUM (Mylan Institutional), ATORVASTATIN CALCIUM (Mylan Pharmaceuticals), ATORVASTATIN CALCIUM (NIVAGEN PHARMACEUTICALS), ATORVASTATIN CALCIUM (Northstar Rx LLC.), ATORVASTATIN CALCIUM (Northwind Pharmaceuticals), ATORVASTATIN CALCIUM (Northwind Pharmaceuticals), ATORVASTATIN CALCIUM (Northwind Pharmaceuticals), ATORVASTATIN CALCIUM (Novadoz Pharmaceuticals LLC), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (NuCare Pharmaceuticals), ATORVASTATIN CALCIUM (PD-Rx Pharmaceuticals), ATORVASTATIN CALCIUM (PD-Rx Pharmaceuticals), ATORVASTATIN CALCIUM (PD-Rx Pharmaceuticals), ATORVASTATIN CALCIUM (PD-Rx Pharmaceuticals), ATORVASTATIN CALCIUM (PD-Rx Pharmaceuticals), ATORVASTATIN CALCIUM (PD-Rx Pharmaceuticals), ATORVASTATIN CALCIUM (Preferred Pharmaceuticals), ATORVASTATIN CALCIUM (Preferred Pharmaceuticals), ATORVASTATIN CALCIUM (Preferred Pharmaceuticals), ATORVASTATIN CALCIUM (Preferred Pharmaceuticals), ATORVASTATIN CALCIUM (Preferred Pharmaceuticals), ATORVASTATIN CALCIUM (Preferred Pharmaceuticals), ATORVASTATIN CALCIUM (Preferred Pharmaceuticals), ATORVASTATIN CALCIUM (Preferred Pharmaceuticals), ATORVASTATIN CALCIUM (Proficient Rx LP), ATORVASTATIN CALCIUM (Proficient Rx LP), ATORVASTATIN CALCIUM (Proficient Rx LP), ATORVASTATIN CALCIUM (Proficient Rx LP), ATORVASTATIN CALCIUM (Proficient Rx LP), ATORVASTATIN CALCIUM (Proficient Rx LP), ATORVASTATIN CALCIUM (Proficient Rx LP), ATORVASTATIN CALCIUM (QPharma), ATORVASTATIN CALCIUM (QPharma), ATORVASTATIN CALCIUM (QPharma), ATORVASTATIN CALCIUM (Quality Care Products), ATORVASTATIN CALCIUM (REMEDYREPACK), ATORVASTATIN CALCIUM (REMEDYREPACK), ATORVASTATIN CALCIUM (REMEDYREPACK), ATORVASTATIN CALCIUM (REMEDYREPACK), ATORVASTATIN CALCIUM (REMEDYREPACK), ATORVASTATIN CALCIUM (REMEDYREPACK), ATORVASTATIN CALCIUM (REMEDYREPACK), ATORVASTATIN CALCIUM (REMEDYREPACK), ATORVASTATIN CALCIUM (REMEDYREPACK), ATORVASTATIN CALCIUM (REMEDYREPACK), ATORVASTATIN CALCIUM (RPK Pharmaceuticals), ATORVASTATIN CALCIUM (RPK Pharmaceuticals), ATORVASTATIN CALCIUM (RPK Pharmaceuticals), ATORVASTATIN CALCIUM (RPK Pharmaceuticals), ATORVASTATIN CALCIUM (RedPharm Drug), ATORVASTATIN CALCIUM (RedPharm Drug), ATORVASTATIN CALCIUM (RedPharm Drug), ATORVASTATIN CALCIUM (Sandoz), ATORVASTATIN CALCIUM (ScieGen Pharmaceuticals), ATORVASTATIN CALCIUM (St Mary's Medical Park Pharmacy), ATORVASTATIN CALCIUM (St. Mary's Medical Park Pharmacy), ATORVASTATIN CALCIUM (St. Mary's Medical Park Pharmacy), ATORVASTATIN CALCIUM (St. Mary's Medical Park Pharmacy), ATORVASTATIN CALCIUM (Sun Pharmaceutical Industries), ATORVASTATIN CALCIUM (Teva Pharmaceuticals USA), ATORVASTATIN CALCIUM (Zydus Pharmaceuticals (USA)), ATORVASTATIN CALCIUM (August Pharmaceutical), ATORVASTATIN CALCIUM (Biocon Pharma Inc.,), ATORVASTATIN CALCIUM (Graviti Pharmaceuticals Private Limited)
組成式   
(C33H34FN2O5)2. 3H2O. Ca
質量    
1208.4846
分子量   
1209.3876
構造式   
Simcomp   
クラス   
代謝酵素基質薬
 DG01633  CYP3A/CYP3A4基質薬
  DG02913  CYP3A4基質薬
トランスポーター基質薬
 DG01665  ABCB1基質薬
 DG01913  ABCG2基質薬
 DG02856  SLCO1B1基質薬
 DG02932  SLCO1B3基質薬
Unclassified
 DG01946  脂質低下薬
  DG01660  HMG-CoA還元酵素阻害薬
コード   
薬効分類: 2189
ATCコード: C10AA05
化学構造グループ: DG00355
商品 (DG00355): D02258<JP/US> D11095<US>
商品 (mixture): D08488<JP/US> D10385<JP>
効能    
脂質異常症治療薬, HMG-CoA還元酵素阻害薬
  疾患
高コレステロール血症 [DS:H01635]
家族性高コレステロール血症 [DS:H00155]
ターゲット 
HMGCR [HSA:3156] [KO:K00021]
  パスウェイ
hsa00900  テルペノイド骨格の生合成
代謝    
Enzyme: CYP3A4 [HSA:1576]
Transporter: ABCB1 [HSA:5243], ABCG2 [HSA:9429], SLCO1B1 [HSA:10599], SLCO1B3 [HSA:28234]
相互作用  

構造マップ 
map07024  HMG-CoA 還元酵素阻害薬
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 2  個々の器官系用医薬品
  21  循環器官用薬
   218  高脂血症用剤
    2189  その他の高脂血症用剤
     D02258  アトルバスタチンカルシウム水和物 (JP18); アトルバスタチンカルシウム
医療用医薬品のATC分類 [BR:jp08303]
 C 循環器系
  C10 脂質修飾剤
   C10A 脂質修飾剤、単剤
    C10AA HMG-CoA 還元酵素阻害薬
     C10AA05 アトルバスタチン
      D02258  アトルバスタチンカルシウム水和物 (JP18) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 心血管治療薬
  脂質異常症治療薬, ヒドロキシメチルグルタリルコエンザイムA還元酵素阻害薬
   アトルバスタチン
    D02258  アトルバスタチンカルシウム水和物 (JP18)
医薬品グループ [BR:jp08330]
 代謝酵素基質薬
  DG01633  CYP3A/CYP3A4基質薬
   DG02913  CYP3A4基質薬
    DG00355  アトルバスタチン
     D02258  アトルバスタチンカルシウム水和物
 トランスポーター基質薬
  DG01665  ABCB1基質薬
   DG00355  アトルバスタチン
    D02258  アトルバスタチンカルシウム水和物
  DG01913  ABCG2基質薬
   DG00355  アトルバスタチン
    D02258  アトルバスタチンカルシウム水和物
  DG02856  SLCO1B1基質薬
   DG00355  アトルバスタチン
    D02258  アトルバスタチンカルシウム水和物
  DG02932  SLCO1B3基質薬
   DG00355  アトルバスタチン
    D02258  アトルバスタチンカルシウム水和物
 Unclassified
  DG01946  脂質低下薬
   DG01660  HMG-CoA還元酵素阻害薬
    DG00355  アトルバスタチン
     D02258  アトルバスタチンカルシウム水和物
医薬品クラス [BR:jp08332]
 心血管系用薬
  DG01946  脂質低下薬 [商品一覧]
   D02258  アトルバスタチンカルシウム水和物
ターゲットに基づく医薬品分類 [BR:jp08310]
 酵素
  オキシドレダクターゼ (EC1)
   デヒドロゲナーゼ
    HMGCR
     D02258  アトルバスタチンカルシウム水和物 (JP18) <JP/US>
日本薬局方収載医薬品 [BR:jp08311]
 化学薬品等
  D02258  アトルバスタチンカルシウム水和物
  D02258  アトルバスタチンカルシウム錠
日本の新薬 [jp08318.html]
 新有効成分含有医薬品
  D02258
薬物代謝酵素とトランスポーター [jp08309.html]
 薬物代謝酵素
  D02258
 薬物トランスポーター
  D02258
医薬品グループ [BR:jp08330]
 代謝酵素基質薬
  DG01633  CYP3A/CYP3A4基質薬
   DG02913  CYP3A4基質薬
    DG00355  アトルバスタチン
 トランスポーター基質薬
  DG01665  ABCB1基質薬
   DG00355  アトルバスタチン
  DG01913  ABCG2基質薬
   DG00355  アトルバスタチン
  DG02856  SLCO1B1基質薬
   DG00355  アトルバスタチン
  DG02932  SLCO1B3基質薬
   DG00355  アトルバスタチン
 Unclassified
  DG01946  脂質低下薬
   DG01660  HMG-CoA還元酵素阻害薬
    DG00355  アトルバスタチン
リンク   
CAS: 344423-98-9
PubChem: 7849317
LigandBox: D02258
日化辞: J1.648.241B
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