Danio rerio (zebrafish): 567611
Help
Entry
567611 CDS
T01004
Symbol
itpr1a
Name
(RefSeq) inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 isoform X1
KO
K04958
inositol 1,4,5-triphosphate receptor type 1
Organism
dre
Danio rerio (zebrafish)
Pathway
dre04020
Calcium signaling pathway
dre04070
Phosphatidylinositol signaling system
dre04114
Oocyte meiosis
dre04140
Autophagy - animal
dre04210
Apoptosis
dre04218
Cellular senescence
dre04270
Vascular smooth muscle contraction
dre04371
Apelin signaling pathway
dre04540
Gap junction
dre04621
NOD-like receptor signaling pathway
dre04625
C-type lectin receptor signaling pathway
dre04912
GnRH signaling pathway
Brite
KEGG Orthology (KO) [BR:
dre00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
567611 (itpr1a)
04020 Calcium signaling pathway
567611 (itpr1a)
04070 Phosphatidylinositol signaling system
567611 (itpr1a)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
567611 (itpr1a)
09143 Cell growth and death
04114 Oocyte meiosis
567611 (itpr1a)
04210 Apoptosis
567611 (itpr1a)
04218 Cellular senescence
567611 (itpr1a)
09144 Cellular community - eukaryotes
04540 Gap junction
567611 (itpr1a)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
567611 (itpr1a)
04625 C-type lectin receptor signaling pathway
567611 (itpr1a)
09152 Endocrine system
04912 GnRH signaling pathway
567611 (itpr1a)
09153 Circulatory system
04270 Vascular smooth muscle contraction
567611 (itpr1a)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
dre01009
]
567611 (itpr1a)
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
dre04040
]
567611 (itpr1a)
Protein phosphatases and associated proteins [BR:
dre01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
567611 (itpr1a)
Ion channels [BR:
dre04040
]
Ligand-gated channels
IP3 receptor
567611 (itpr1a)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ins145_P3_rec
RYDR_ITPR
MIR
RIH_assoc
Ion_trans
C_GCAxxG_C_C
Motif
Other DBs
NCBI-GeneID:
567611
NCBI-ProteinID:
XP_005166152
ZFIN:
ZDB-GENE-070604-3
Ensembl:
ENSDARG00000014655
UniProt:
A0A8M2BDG0
LinkDB
All DBs
Position
6:42474549..42542969
Genome browser
AA seq
2711 aa
AA seq
DB search
MVDKLSSFLHIGDVCSLYAEGSTSGFISTLGLVDDRCVVQPDAGDLNNPPKKFRDCLFRL
CPMNRYSAQKQFWKAAKPGGTSTTDTVLLNKLHHAADLEKKQNDSENKKLLGTVIQYGNV
IQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDAAGNEGSWFYIQPFYKLRSIGDNVVIGD
KVVLNPVNAGQPLHASSHQLVDNPGCNEVNSVNCTTSWKIVLFMKWSDNQEIVLKGGDVV
RLFHAEQEKFLTCDEHRKKQYVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWN
SLFRFKHLATGHYLAAEVNPDYEEECLESRSSMDSEHEVIRARARNPQDKVMYTLVSVPD
GNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNQPIDKEEEKPVMLRIGT
SPLKEDKEAFAIVPVSPAEVRDLDFANDASKVLASIAAKLEKGTITQNERRSVTKLLEDL
VYFVVDIPSSAQDVLEITVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEE
LADQRHAPFRHICRLCYRVLRYSQQDYRKNQEYIAKQFRFMQKQIGYDVLAEDTITALLH
NNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICNAVLDPA
NADILIETKLVLSRFEVAGTVLGEGAEEEEEDEEEVWLFWKDSGGEVKSKSIRELAQDAK
DGHTEDQEVINYYRYQLNLFARMCLDRQYLAINKISAQLDVDLILRCMSDEDLPFDLRAS
FCRMMLHMHVDRDPQEQVTPVKYARLWSEIPSQISIDDYDNDGTSSDEVKERFSQTMEFV
ENYLRDVVCQSFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHI
STPFHIKLDREPGKGSNVMRSIHGVGELMTQVVLRGGGFLPASSHNPPDRDEVKAQSEPQ
KQDILVMDTKLKIIEILQFILNVRLDYRISCLLCIFKTEFDESNSQSEPSLSPESPASVQ
GALDFEHIEEQAEGIFGGSSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSRALHLLF
RHFSQRQEVLQAFKQVQLLVTSQDVENYKQIKSDLDQLRSIVEKSELWVYKRQGSDSGLD
AGEVTPEAHHKGVINSSRSNKPKVESTSSSNYRVVKEILLRLSKLCVLEGISGKKNKKQQ
QRLLRNMGAHSVVLELLQIPYEKGEDVQMQEIMTLAHQFLQNFCAGNQQNQALLHKHINL
FLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRSVHYLKFLQTIVKAENK
FIKKCQDIVMAELVTAGEDVLVFYNDRASFQSLVQMMRLERERLDESSALRYHIHLVELL
AVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKMAYVNFLNHCYVDTEVEMKEIY
TSNHMWKLFDDFLVDVCRVCNNTSDRKHADTVLERYVTETIMSIVTTFFSSPFSDQSTSL
QTRQPVFVQLLQGVFRVYHCNWLLPGQKGNVEACIKVLSDVAKGRAIAIPVDLDCQVNNL
FMKSNNIVQKTALSWRLSVRNATRRDSVLTTSRDYRNIIERLQDIVSALEERLRPLVQAE
LSVLVDVLHRPELLFPEHTEAHRKCESGGFICKLIKHTKQLLEENEERLCIKVLQTLREM
MTKDRGYGEKLLGYDDEMDVTEVVDISLPPKQQEDRQRGEALRQLLVNRYYGFRSGGRRE
SLTSFGNSTLTPVGPIKSQPGGLSRAEMSLMEVQCHLDREGASDLVIDLIMNTTSDRVFH
ESILLAIALLEGGNTIIQHSFFKRLTEDKNSEKFFRVFYDRMKVAQVEIKATVTVNTSDL
GNKRRDDNTPDKDTPQRRRGKDSGVVVTDDAREQLLEASAATKKAFGSYRRDADPEETFG
TADGDKGGGDKGTEQGEMSPVILIMQPILRFLQLLCENHNRDLQNFLRCQNNKNNYNLVC
ETLQFLDCICGSTTGGLGLLGLYINQHNVALINQTVESLTEYCQGPCHDNQNCIATHESN
GIDIIIALILNDINPLGRKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKEL
VEVMKMAYQQGEAEFEDEEQENGEDHAASPRNVGHNIYILAHQLSRHNKELQILLKPGGE
DQALEYYTKHTSQIEIVRQDRTMEQIVFPVPNICSFLTNESKLRVYYGTERDEQGSKIND
FFLHADDLFNEMRWQKKLRAQPVLYWCSRNMSFWSNVSFNLAVLINLLVAFFYPLDGVSE
SQLEPSLSLLLWVCLLGSLGFVLMSPRPNAVRVLVISTVLQLGFSVGLQHMLTLLGAFNV
CNKIVFMLSFVGNRGSFTRGYRVMVMDREFLFHLLYLLICILGLFGHVFFYSLLLFDLVN
REETLLNVIKSVTRNGRSIVLTAVLGLILVYLFSIVGYMFFKDDFILEVNRISNGTLEEG
VTLPAGFCDARNGSCLSDDVDEDDVERACDSLWMCMITVLSHGLRSGGGVGDVLRKPSKE
ERLFAARVVYDLLFFFLVIIIVLNLIFGVIIDTFADLRSEKQRKEEILKTTCFICGLERD
KFDNKTVTFEEHIKEEHNLWHYLFFIVLVRVKDSTEYTGPESYVAQMIKEHNLDWFPRMR
AMSLVSSDGEGEQNELRSLQEKLESTMRLVSNLTNQLTELKEQMTEQRKHKQRLGLLGNP
AHLNINPQQPA
NT seq
8136 nt
NT seq
+upstream
nt +downstream
nt
atggtggacaaattgtctagtttcctgcacattggggacgtttgttccctttatgctgaa
ggctctactagtggcttcatcagcactctggggttggttgatgaccgatgtgttgttcaa
ccagatgccggagacctgaataacccacctaaaaagtttcgggactgtctgttcagactg
tgtcccatgaacagatattcggcacagaaacagttctggaaagctgccaaacctggagga
actagcaccacagatactgtcctgcttaacaaactccatcatgctgctgatttagagaag
aaacaaaatgattctgagaacaaaaagctgcttggaaccgtcattcagtatggcaatgtc
atccagcttctccatctgaagagtaataaatatctgacggtgaacaagcgtttgccggct
cttcttgagaagaatgccatgcgtgtgacgctggacgctgcagggaatgaaggctcgtgg
ttttacatccagcccttctataagctgcgctctataggggataatgtggtcattggagat
aaggtcgtgttaaaccctgtcaatgccggacagccgctgcacgccagcagccatcagctt
gtggataatccaggctgcaatgaagtgaattcagtgaactgcaccaccagttggaaaatc
gttctcttcatgaaatggagcgacaaccaggagattgtcttgaaaggaggtgacgtggtg
aggctgtttcatgcagagcaggagaagtttctgacatgtgatgagcatcggaaaaagcag
tatgtgtttctgcgtaccaccggacgccagtctgcaacctccgccactagtagcaaagca
ctctgggaggtggaggtggttcagcatgatccctgccgaggtggagccggctactggaac
agcctctttaggtttaaacacttagccaccggccattaccttgctgcagaggtaaatcca
gactatgaagaagaatgcctggagtcccgctcctctatggattcggagcatgaagtgatt
cgggctcgtgcacgtaaccctcaggataaggtgatgtacacactggtgtctgttcctgat
ggaaatgacatatcctccatctttgagcttgaccctacaactttgaggggcggagactca
cttgtgccaagaaactcgtatgtgaggctcaggcatctctgcaccaacacgtgggtccac
agcaccaaccagccaatagataaagaggaagagaaaccggtcatgctcagaataggaacg
tctcctctgaaggaagataaagaggcgtttgctatagtaccagtctctccagctgaggtt
cgagatctggattttgctaatgatgctagtaaagtgttggcttccattgctgccaaactg
gagaagggcaccattacccagaatgagaggaggtcagtgacgaagctgttggaggatctg
gtgtattttgtggtggacatacccagcagtgctcaagatgtgctggagatcacagtcaac
aaacccaacagagagcgacagaaactcatgagagagcagaacattcttaaacagatcttc
aagctgctgcaggcgccatttacagacagcggggacggccctatgttgcgattagaagag
ctcgcagaccagcgtcatgcaccctttcgacacatttgcagactctgttacagagtccta
cgttactcacaacaggactatcgcaaaaatcaggagtacatagcaaagcagttccgcttc
atgcagaagcagataggatatgatgtgctggctgaagacacaattacagcccttctgcac
aacaacaggaagctcctagagaaacacatcacagcagctgaaatagatacctttgtcagt
ctggtccgcaagaacagagagcccagatttctggattacttgtcagatctgtgtgtgtcg
atgaataaatccatcccggtcactcaagagctcatctgtaatgctgtgctggacccagcc
aatgcagacattctcatcgaaaccaagcttgtgttgtcacggtttgaggtggcaggaacg
gtgttgggtgaaggtgcggaggaggaagaggaggatgaagaggaggtctggctgttctgg
aaggacagtggaggagaggtgaagagtaaaagcatacgagagcttgcacaggacgcaaaa
gatggacatacagaggaccaggaagtcatcaattattacagatatcagctgaatttgttt
gctcggatgtgtctggatcgacagtatcttgcgattaacaagatatcagcacagctggat
gtggatctgattctgcgctgcatgtcagatgaagatttgccctttgacctcagagcatcg
ttctgccgcatgatgctgcacatgcatgtagaccgtgaccctcaggagcaggtcaccccg
gtcaaatatgctcgactgtggtctgaaatcccatcacaaatttccattgatgattatgat
aatgatgggacgtcaagtgatgaagtgaaagagcgcttctctcagacgatggagtttgtg
gagaattacctgagggatgttgtctgccagagtttcccgttctctgataaggagaaaaac
aaactcacttttgaggtggtgaacctggcaagaaacctgatctattttggtttctataac
ttcagtgatctgctaaggttaacaaaaatcctattggcaatcctggactgtgtccacata
agcactcccttccacatcaagctggatagagaacccggtaaaggaagtaacgtgatgcgc
tccatccatggggtgggagagctgatgacacaggtggtgttgaggggtgggggatttctg
ccagcctccagccacaatcctcctgacagagacgaagtgaaagcacaaagtgaacctcag
aaacaggacatactggtgatggacactaaactcaagatcatcgagatcctgcagtttatt
ctgaatgtgcggttggactacaggatctcctgcctcctctgtatctttaagacagagttt
gatgaaagtaactctcaaagtgaaccatctttaagcccagaatctcctgccagcgttcaa
ggtgcgctagactttgagcacattgaagagcaggcggagggtatttttggaggaagtagt
gaagagaacaccccgctggatcttgatgatcatggtggacggacatttctgagggtcctg
cttcacctgaccatgcatgactatcctccgctggtatctcgagctcttcacctgctcttc
agacactttagccaacgccaggaggtcctacaggccttcaaacaggttcagctcctggtg
accagtcaggatgtggaaaactataaacagatcaagtcagatttggaccagctgaggtca
atagtagagaaatcagagttgtgggtgtataagagacaaggctcagactcaggactggat
gctggagaagtcacccctgaagcccaccacaagggtgtcatcaactcgagtagatcaaac
aaacccaaagtggaaagtaccagcagctcgaactacagagtcgtgaaagagatcctgctg
aggctgagcaaactgtgtgttttggagggcatctctggcaagaagaataagaaacagcag
cagcggctcctcaggaacatgggagctcacagtgtggtcctcgaactgttgcaaatccct
tatgagaagggggaggatgtccagatgcaggagatcatgaccttagcacatcagttcctt
caaaacttctgtgctggaaatcagcagaaccaggcacttctacacaaacacatcaacctg
ttcctcaaccctgggatcctggaggcggtgaccatgcagcatatcttcatgaataatttc
cagttgtgtagtgagattaatgagcgggtcgtgcagcattttgtgcactgcatcgagaca
cacggccgcagcgtgcactacctcaagttcctgcagaccattgtcaaggcagagaacaag
ttcatcaagaaatgccaagacatcgtcatggctgagctggtgactgcaggtgaggatgtg
ctggtgttctataatgaccgggcgtcttttcagtcattggttcagatgatgcgtcttgag
cgggaacgacttgatgagagcagtgcactcaggtatcacattcacctggtggagttgctg
gctgtgtgcactgaaggcaagaacgtctacactgagatcaaatgcaactcgctgctccct
ctcgatgatattgtacgtgtggtcacacatgaggactgcatccctgaggtgaagatggcc
tacgtgaacttcctgaatcactgttatgttgatacagaggttgagatgaaggagatctac
accagcaatcacatgtggaaactttttgatgattttctggtggacgtctgcagagtgtgc
aataacacaagtgaccgtaaacacgctgacacagttctggagagatacgttacagagacc
ataatgagcatcgtcaccacctttttcagctcaccattctcagaccagagcacaagtttg
cagacccggcagccggtgtttgtgcagctgctgcagggagtgtttcgtgtatatcactgc
aactggcttctcccaggtcagaaggggaatgtggaagcctgcatcaaagtgctgagtgac
gtggccaaaggcagagccatagccattcctgtggatctggactgtcaggtgaataatctg
ttcatgaagtccaacaacattgtgcagaaaacagccctcagctggagactctctgtccgt
aacgcgactcggagagactctgttctgaccacctctcgagactatcgcaacatcattgaa
agactacaggatatagtgtctgcattggaggagcggttgaggcctctggttcaggctgag
ttgtcagtgttggtggatgttctccatcgcccagagctgctgtttccagagcacactgaa
gcccaccgcaagtgtgagagtggaggcttcatctgcaagttgataaaacacactaagcag
cttctagaagaaaacgaagagaggctttgcatcaaagtccttcagacactccgagagatg
atgaccaaagacagaggatatggagagaagcttctgggatatgatgatgagatggatgtc
acggaggtggtggatatcagtctgccacccaaacagcaggaggatcggcagaggggggag
gcccttcggcagctgctcgtcaatcgttactatggcttcaggagtggtgggcggagagaa
agtctgacctcgtttggtaactccaccctaactcctgtcgggccaatcaagagccagcca
ggggggttgagcagggctgagatgtcattaatggaggtgcagtgtcatctagaccgtgaa
ggggcatcggatcttgtcattgatctcatcatgaacactaccagcgaccgcgtcttccat
gaaagcattctgttggccatcgcactgttggagggcggaaacaccatcatacagcattcc
ttcttcaaacgtttaacagaagacaaaaattcagagaagtttttcagggtgttttatgac
agaatgaaagtggctcaggtggagatcaaagccacggttactgtcaacactagtgacctc
ggcaacaagcggcgtgacgacaacactccagacaaagatactccacaacgccgcagaggt
aaagactccggtgtggtggtgacagatgatgctcgtgagcagctgttggaggcttcagct
gcgactaagaaggcctttggttcatatcgtcgagatgctgatcccgaggagacgtttggc
acggctgatggagataaaggaggtggagataaaggcacagagcagggcgagatgagccct
gtcatcctcataatgcagccaatcctgcgcttcctgcagctgctgtgcgaaaaccacaat
cgagacctgcagaattttctgcgctgtcagaacaataaaaacaactataatctggtgtgt
gagacgctgcagttcctggactgtatctgtggcagcacaacaggaggcctggggctgtta
ggactctacatcaaccagcataacgtagcgctcattaatcagactgtagagagcctcact
gaatactgtcaaggtccctgccatgacaatcagaattgcattgccacccatgagtctaat
ggcatcgacatcattattgcactgattctgaatgatattaatccactgggcaggaagaga
atggatctggttctagaactaaagaataatgcatctaagctgctgctggccatcatggag
agccgtcatgacagtgagaatgcagaaagaattctgtacaacatgagaccaaaagaacta
gtggaggtgatgaaaatggcctaccagcagggggaggcagagtttgaggatgaggaacag
gagaatggagaggatcatgcagcatcgcctcgcaatgttggacacaacatctatattctt
gcacatcagctgtcgcgtcacaataaggaattgcaaatactactgaaaccaggtggagag
gaccaggccctggagtattacacaaaacacacctcacagatagagatagttcgacaggat
cgcactatggaacagattgtgtttcctgtaccaaatatctgctcttttctgacaaatgag
tccaagctgcgtgtgtactatggtacagagagagacgagcaaggcagtaaaataaatgac
ttcttcttgcatgcagacgacctctttaatgaaatgaggtggcagaaaaaactaagagct
cagccagtgctgtactggtgcagcaggaacatgtcgttttggagtaacgtttcctttaat
ctggcggtgctcattaatttgctggtggcatttttctaccctctggatggagtgagcgaa
agccagctggaaccttctctgtctctgttgctgtgggtttgtttgttgggctcactgggc
ttcgtgttgatgtccccgaggccaaatgcagtgcgggtgctggtcatctccactgtcctg
cagttgggcttctctgtagggctgcagcacatgctcacactcctgggagctttcaatgtt
tgtaataagatcgtgttcatgctgagctttgtgggtaaccgtgggtcattcacccggggt
tatcgggtgatggtcatggatagagagttcctgtttcatctgctgtaccttctcatctgc
atactgggcctttttggacacgtcttcttttacagtcttctgttgtttgacctggtgaac
cgggaagagactcttctgaacgtcatcaagagtgtgactcgaaacggccgctccatcgtc
ttgaccgcagtgctgggcctcatcctggtctacctcttttctattgttggatatatgttt
ttcaaagatgacttcatcctggaggtgaaccgcatctccaacggcactctggaggagggg
gtgactttacctgctggtttttgtgatgcgagaaacgggtcgtgtctttctgatgatgtt
gacgaggatgacgtggagcgcgcgtgtgattctctatggatgtgtatgatcactgtactc
agtcatggcctcaggagcggtggaggagttggagatgtcctgcgcaaaccgtctaaagag
gagcgtctgttcgccgcacgggtggtgtacgatctcctgttcttcttcctggtgatcatc
attgtgttgaatctgatcttcggtgtgatcattgacacatttgcagatctgagaagcgag
aagcagagaaaagaggagatcttgaagaccacatgcttcatctgtggtctggagagagat
aagtttgataataaaacggtgacgtttgaagagcacatcaaggaggagcacaacctgtgg
cattacctcttcttcatagtgctggtgcgggtcaaagactccaccgaatacacgggaccc
gagagctacgtcgctcagatgatcaaggagcacaatctggactggtttcctcgtatgagg
gcgatgtctctggtcagcagtgatggagaaggtgaacagaatgaactgcgcagcttacag
gagaaactcgagtccacaatgaggctcgtctctaatcttaccaatcagctcacagagctc
aaagagcagatgactgagcaaaggaaacacaagcagaggctcggtctgctgggaaacccc
gcccacctcaacatcaacccacagcagccagcatga
DBGET
integrated database retrieval system
