KEGG   Equus caballus (horse): 100057212
Entry
100057212         CDS       T01058                                 
Name
(RefSeq) prostaglandin F synthase 1
  KO
K04119  aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
Organism
ecb  Equus caballus (horse)
Pathway
ecb00140  Steroid hormone biosynthesis
ecb00590  Arachidonic acid metabolism
ecb00790  Folate biosynthesis
ecb01100  Metabolic pathways
ecb04913  Ovarian steroidogenesis
ecb05208  Chemical carcinogenesis - reactive oxygen species
Module
ecb_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
ecb_M00977  C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    100057212
   00590 Arachidonic acid metabolism
    100057212
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    100057212
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    100057212
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    100057212
Enzymes [BR:ecb01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.51  3(or 17)beta-hydroxysteroid dehydrogenase
     100057212
    1.1.1.188  prostaglandin-F synthase
     100057212
    1.1.1.213  3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
     100057212
    1.1.1.357  3alpha-hydroxysteroid 3-dehydrogenase
     100057212
SSDB
Motif
Pfam: Aldo_ket_red
Other DBs
NCBI-GeneID: 100057212
NCBI-ProteinID: XP_001500793
Ensembl: ENSECAG00000000144
UniProt: F6QZ61
LinkDB
Position
29:29890576..29916671
AA seq 323 aa
MDPKCWRVELNDGCFIPVLGFGTYAPEEVPKSMAGAATKVAIDVGFRHIDSAYLYQNEEE
VGEALREKIRDGTVKREDIFYTTKLWATFLRPELVRPALERSLKKLRLDYVDLFIIHAPI
AMKPGEELVPKDAGGKIILDTVDFCDTWEALEKCKDAGLTKSIGVSNFNHKQLEMILNKP
GLKYKPVCNQVECHPYLNQSKLLEFCKSQDIVLVAYSALGSHRDPNWVERDSPYLLEDPI
LNAIAKKHNRSPGQIALRYQLQRGVVVLAKSFNEKRIQENFQVFDFELTPEDMKAIDGLN
RNFRYEKLLFAVDHLYYPYSEEY
NT seq 972 nt   +upstreamnt  +downstreamnt
atggatcccaaatgttggcgtgtggaactaaatgatggctgcttcattcctgttctggga
tttggcacctatgcacctgaagaggttcctaagagcatggctggagcggccacgaaagtg
gctattgatgtgggtttccgtcacattgactcagcgtacctctatcagaatgaggaggag
gtcggcgaggcccttcgagagaagatcagggatggcactgtgaagagagaggacatattc
tacaccaccaagctttgggctactttccttcgaccagaactggttcgaccagctctggaa
agatcactgaagaaacttcgactggactacgtagatctcttcatcattcatgcgcctatt
gctatgaagcctggggaggagcttgtgccaaaggatgctggtgggaaaattattttagat
acagtggacttttgtgacacatgggaggccctggagaagtgtaaagatgccggtttaacc
aagtcaatcggggtgtccaatttcaatcacaaacagctggagatgatcctgaacaagcca
gggctcaagtacaagcctgtttgcaaccaggtggaatgccacccttacctcaaccagagc
aaactgctggagttctgcaagtcccaggacattgttctagttgcctacagtgccctgggg
tcccatagagacccaaactgggtggaaagagatagtccatatctcctggaggatccaatc
ttgaatgctattgccaagaaacacaatcgaagtccaggccagattgctctgcgctaccag
ctacaacgtggtgtggtggtcctggccaagagcttcaatgagaagagaatccaagagaac
ttccaggtttttgactttgaattgactccagaagacatgaaagcaattgatggtctcaac
agaaatttccgatatgaaaaattgctttttgctgttgatcacctttattatccgtattct
gaagaatattga

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