Equus caballus (horse): 100065563 Help Entry 100065563         CDS       T01058                                  Symbol ADCY1 Name (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism ecb  Equus caballus (horse) Pathway ecb00230   Purine metabolism ecb01100   Metabolic pathways ecb01522   Endocrine resistance ecb04015   Rap1 signaling pathway ecb04020   Calcium signaling pathway ecb04022   cGMP-PKG signaling pathway ecb04024   cAMP signaling pathway ecb04062   Chemokine signaling pathway ecb04072   Phospholipase D signaling pathway ecb04114   Oocyte meiosis ecb04211   Longevity regulating pathway ecb04213   Longevity regulating pathway - multiple species ecb04261   Adrenergic signaling in cardiomyocytes ecb04270   Vascular smooth muscle contraction ecb04371   Apelin signaling pathway ecb04540   Gap junction ecb04611   Platelet activation ecb04713   Circadian entrainment ecb04714   Thermogenesis ecb04720   Long-term potentiation ecb04723   Retrograde endocannabinoid signaling ecb04724   Glutamatergic synapse ecb04725   Cholinergic synapse ecb04727   GABAergic synapse ecb04750   Inflammatory mediator regulation of TRP channels ecb04911   Insulin secretion ecb04912   GnRH signaling pathway ecb04913   Ovarian steroidogenesis ecb04914   Progesterone-mediated oocyte maturation ecb04915   Estrogen signaling pathway ecb04916   Melanogenesis ecb04918   Thyroid hormone synthesis ecb04921   Oxytocin signaling pathway ecb04923   Regulation of lipolysis in adipocytes ecb04925   Aldosterone synthesis and secretion ecb04926   Relaxin signaling pathway ecb04927   Cortisol synthesis and secretion ecb04928   Parathyroid hormone synthesis, secretion and action ecb04934   Cushing syndrome ecb04935   Growth hormone synthesis, secretion and action ecb04970   Salivary secretion ecb04971   Gastric acid secretion ecb04972   Pancreatic secretion ecb04976   Bile secretion ecb05032   Morphine addiction ecb05142   Chagas disease ecb05146   Amoebiasis ecb05163   Human cytomegalovirus infection ecb05166   Human T-cell leukemia virus 1 infection ecb05200   Pathways in cancer ecb05207   Chemical carcinogenesis - receptor activation ecb05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ecb00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100065563 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100065563 (ADCY1)    04371 Apelin signaling pathway     100065563 (ADCY1)    04020 Calcium signaling pathway     100065563 (ADCY1)    04072 Phospholipase D signaling pathway     100065563 (ADCY1)    04024 cAMP signaling pathway     100065563 (ADCY1)    04022 cGMP-PKG signaling pathway     100065563 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     100065563 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     100065563 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100065563 (ADCY1)    04062 Chemokine signaling pathway     100065563 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     100065563 (ADCY1)    04923 Regulation of lipolysis in adipocytes     100065563 (ADCY1)    04912 GnRH signaling pathway     100065563 (ADCY1)    04913 Ovarian steroidogenesis     100065563 (ADCY1)    04915 Estrogen signaling pathway     100065563 (ADCY1)    04914 Progesterone-mediated oocyte maturation     100065563 (ADCY1)    04921 Oxytocin signaling pathway     100065563 (ADCY1)    04926 Relaxin signaling pathway     100065563 (ADCY1)    04935 Growth hormone synthesis, secretion and action     100065563 (ADCY1)    04918 Thyroid hormone synthesis     100065563 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     100065563 (ADCY1)    04916 Melanogenesis     100065563 (ADCY1)    04925 Aldosterone synthesis and secretion     100065563 (ADCY1)    04927 Cortisol synthesis and secretion     100065563 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100065563 (ADCY1)    04270 Vascular smooth muscle contraction     100065563 (ADCY1)   09154 Digestive system    04970 Salivary secretion     100065563 (ADCY1)    04971 Gastric acid secretion     100065563 (ADCY1)    04972 Pancreatic secretion     100065563 (ADCY1)    04976 Bile secretion     100065563 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     100065563 (ADCY1)    04727 GABAergic synapse     100065563 (ADCY1)    04725 Cholinergic synapse     100065563 (ADCY1)    04720 Long-term potentiation     100065563 (ADCY1)    04723 Retrograde endocannabinoid signaling     100065563 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100065563 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     100065563 (ADCY1)    04213 Longevity regulating pathway - multiple species     100065563 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     100065563 (ADCY1)    04714 Thermogenesis     100065563 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100065563 (ADCY1)    05207 Chemical carcinogenesis - receptor activation     100065563 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100065563 (ADCY1)    05163 Human cytomegalovirus infection     100065563 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     100065563 (ADCY1)    05142 Chagas disease     100065563 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     100065563 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100065563 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100065563 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100065563 (ADCY1) Enzymes [BR:ecb01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100065563 (ADCY1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom HNOBA Motif Other DBs NCBI-GeneID:  100065563 NCBI-ProteinID:  XP_005614918 Ensembl:  ENSECAG00000025044 VGNC:  15086 LinkDB All DBs Position 4:16027478..16169399 Genome browser AA seq 907 aa AA seqDB search MFGVFVRILAERSQRKSFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLK PPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCR RIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVL CGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSF LKAHNIETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFS NVMTCEDDDKRRALRTASEKLRNRSSFSANVVYTTPGTRVNRYISRLLEARQPELEMADL NFFTLKYKQAERERKYHQLQDEYFTSAVVLALALAALFSLVYLLIIPQNLAVLLLLVFSI CFLVACVLYLHITRVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWAWSSSPNG SLVFLSSGGRSPVLPAPPCESAPHALLCGLVGTLPLAIFLRVSSLPKMILLSVLTASYIL VLELSGYTKAVGGGTVSGRSFEPIVAILLFSCTLALHARQVDVKLRLDYLWAVQAEEERD DMERVKLDNKRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIEL DGNNMGVECLRLLNEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGAKAKKCI SSHLGTLADFAIEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVN VASRMDSTGVQGRIQVTEEVHRLLRRGAYRFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQ SRSLNSERKMYPYGRAGLQTRLATGHPPVPAVAGLPVTAGLGALQGSGIAPGPPGPPLPP GAAGKEA NT seq 2724 nt NT seq  +upstreamnt  +downstreamnt atgttcggcgtctttgtgaggatcctggccgagcgctcccagaggaagtccttcctgcag gcccgaaactgcatcgaggaccggctgcgactggaggacgagaatgagaagcaggagcgg ctgctcatgagtctcttgccccggaacgtcgccatggagatgaaggaggacttcctgaag ccccccgagaggattttccacaagatttacatccagcggcatgacaacgtgagcatcctc ttcgcagacatcgtgggcttcacgggcttggcgtctcagtgcacggcccaggagctggtg aaactcctcaacgagctcttcggcaagtttgatgaattggccacggagaaccactgccgc cgcatcaagatcctcggagactgttactactgcgtgtctggcctcacccagcccaagact gaccacgcccattgctgtgtggagatgggcctggacatgatcgacaccatcacgtccgtg gccgaggccaccgaggtggacctgaacatgcgtgtggggctgcacaccggcagggtcctc tgcggggtcctgggcctgcgcaagtggcagtatgatgtgtggtccaacgacgtgaccttg gccaatgtcatggaggccgccggcctgccggggaaggttcatatcacgaagaccaccctg gcgtgcttgaatggcgactacgaggtggaaccaggtcacggacacgagaggaacagtttt ctgaaagctcacaatatcgagaccttttttattgtgccatcgcatcggcgaaagatattt ccggggctgattctctcagacataaagccggccaagaggatgaagttcaagaccgtgtgc tacctgctggtgcagctcatgcactgccggaagatgttcaaggcggagatccccttctcc aacgtcatgacctgcgaggatgatgacaagcggagggctttgagaacagcctcggaaaaa ctcagaaaccgctcgtctttctctgcgaacgttgtgtacaccaccccgggcacgcgcgtc aataggtacatcagccgcctcctagaagcccgccagccagaactggagatggcagacctg aacttcttcaccctgaagtacaagcaagctgagcgagagcgaaagtaccaccagctccag gacgagtacttcaccagcgccgtcgtgctcgccctcgccctggccgccttattcagcctc gtctaccttctgatcatcccgcagaacttggctgtcctgctcctgctggtgttctccatc tgcttcctggtggcctgtgtcctgtacctgcacatcacccgggtccagtgttttccaggg tgcctgacgatccagattcgtaccgtcctgtgtattttcatagtggtcttaatctattct gtggcccaaggatgtgtggtgggctgtctgccctgggcctggagctccagtcccaacggg tctctggtgttcctgtcgtccggcggccggagcccagtgctgcctgccccgccctgcgag tctgcaccccacgccctgctctgtggcctggtgggcaccctcccgctggccatattcctg cgggtctcttccttgcccaaaatgatcctgctctccgtgctcacggcgtcctacatcctg gtcctggagctcagcgggtacaccaaggccgtggggggcggcactgtctctgggcgcagc ttcgagccgattgtggccatcctgctgttctcgtgcacgctggccctgcacgcccggcag gtggacgtcaagctgcggctggactacctctgggctgtgcaggcagaggaggagcgagac gacatggagcgggtgaagctggacaataagaggattctcttcaatctcctgccggcccac gtcgcccagcatttcctcatgtccaacccccggaacatggacctctactaccagtcgtac tcgcaggtgggcgtcatgttcgcctccatccccaacttcaacgacttctacatcgagctg gatggcaacaacatgggggtggagtgcctgcgcctcctgaacgagatcattgccgacttc gacgagctcatggacaaagacttttacaaggacctggagaagatcaagaccattgggagc acttatatggccgcggtgggattggcgcccacggctggggccaaggctaagaagtgtatc tcctcccacctcggcacgctggcggattttgccatcgagatgttcgacgtcctggatgag atcaactaccagtcttacaatgacttcgtgctccgtgtcggcatcaacgttggccccgtg gtggctggggtgattggggctcgcaggccgcagtatgacatctggggaaacactgtcaac gtggccagtcggatggacagcaccggggtccagggcagaatccaggtgacggaggaggtg caccggctgctgcggcggggtgcgtaccgtttcgtgtgccgaggcaaagtcagtgtcaag ggcaagggcgagatgctaacatacttcctggaaggcaggaccgacggaaatggctcccaa tccaggtccctgaactcggagcggaaaatgtatccttacggcagagctggcctccagacc agactggccacgggccacccccctgtgcccgccgtggctggcctcccggtcacagctggg ctgggggctctgcagggctcggggatcgcccctgggcctcccggcccacccctgccccct ggagcagctggaaaggaggcttag

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