KEGG   Escherichia coli O127 H6 E2348/69 (EPEC): E2348C_2378
Entry
E2348C_2378       CDS       T00796                                 
Symbol
nrdA
Name
(GenBank) ribonucleoside diphosphate reductase 1, alpha subunit
  KO
K00525  ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
Organism
ecg  Escherichia coli O127:H6 E2348/69 (EPEC)
Pathway
ecg00230  Purine metabolism
ecg00240  Pyrimidine metabolism
ecg01100  Metabolic pathways
ecg01232  Nucleotide metabolism
Module
ecg_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
ecg_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:ecg00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    E2348C_2378 (nrdA)
   00240 Pyrimidine metabolism
    E2348C_2378 (nrdA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:ecg03400]
    E2348C_2378 (nrdA)
Enzymes [BR:ecg01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     E2348C_2378 (nrdA)
DNA repair and recombination proteins [BR:ecg03400]
 Prokaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    E2348C_2378 (nrdA)
SSDB
Motif
Pfam: Ribonuc_red_lgC Ribonuc_red_lgN ATP-cone
Other DBs
NCBI-ProteinID: CAS09926
UniProt: B7UFP6
LinkDB
Position
2472088..2474373
AA seq 761 aa
MNQNLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELRSHIQFYDGIKTSDIHE
TIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPALYDHVVKMVEMSKYDNHLL
EDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVAACL
FSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIECGDSLDSINAT
SSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGGVRGG
AATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITLFSPSD
VPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFSLMMQERASTGRIYIQNVDHC
NTHSPFDPAIAPVRQSNLCLEIALPTKPLNDVNDENGEIALCTLSAFNLGAINSLDELEE
LAILAVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYLAKHGKRYSDGSANNLT
HKTFEAIQYYLLKASNELAKEQGACPWFNETTYAKGILPIDTYKKDLDAIANEPLHYDWE
ALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYE
HLHDAYELLWEMPGNDGYLQLVGIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLT
AYKFGVKTLYYQNTRDGAEDAQDDLVPSIQDDGCESGACKI
NT seq 2286 nt   +upstreamnt  +downstreamnt
atgaatcagaatctgctggtgacaaagcgcgacggtagcacagagcgcatcaatctcgac
aaaatccatcgcgttctggattgggcggcagaaggactgcataacgtttcgatttcccag
gtcgagctgcgctcccacattcagttttatgacggtatcaagacctctgacatccacgaa
actattatcaaggctgccgcagacctgatctcccgtgatgcgccggattatcagtatctc
gccgcacgtctggcgatcttccacctgcgtaaaaaagcctacggtcagtttgagccgcct
gcgctgtacgaccatgtggtgaaaatggtcgagatgagcaaatacgataatcatctgctg
gaagactacacggaagaagagttcaagcagatggacacgtttatcgatcacgaccgtgat
atgaccttctcttatgctgccgttaagcagctggaaggcaaatatctggtacagaaccgc
gtgaccggcgaaatctacgaaagcgcccagttcctttatattctggttgccgcgtgcctg
ttctcgaactacccgcgtgaaacgcgcctgcaatacgtgaagcgtttttacgacgcggtt
tccacatttaaaatttcgctgccgacgccaatcatgtccggcgtgcgtaccccgactcgt
cagttcagctcatgcgtgctgatcgagtgcggcgacagcctggattccattaacgccacc
tccagcgcgattgttaaatacgtttcccagcgtgccgggatcggcatcaacgccgggcgt
attcgtgcgctgggtagcccgattcgcggtggcgaagcgttccataccggttgtattccg
ttctacaaacatttccagaccgcggtgaaatcctgctctcagggcggtgtgcgcggcggt
gcggcaacgctgttctacccgatgtggcatctggaagtggaaagcctgctggtgttgaaa
aacaaccgtggtgtggaaggcaaccgcgtgcgtcatatggactacggggttcaaatcaac
aaactgatgtatacccgtctgctgaaaggtgaagatatcactctgttcagcccgtccgac
gtaccggggctgtacgacgcgttcttcgccgatcaggaagagtttgaacgtctgtatacc
aaatatgagaaagacgacagcatccgcaagcagcgtgtgaaagccgttgagctgttctcg
ctgatgatgcaggaacgtgcatctaccggtcgtatctatattcagaacgttgaccactgt
aatacccatagcccgtttgatccggccatcgcgccagtgcgccagtctaacctgtgcctg
gaaatcgccctgccgaccaaaccgctgaacgacgtcaacgacgagaacggtgaaatcgcg
ctgtgtacgctgtctgctttcaacctgggcgcaattaacagcctggatgaactggaagag
ctggcaattctggcagtacgcgcactcgacgcgctgctggattatcaggattacccgatc
ccggccgccaaacgtggagcgatgggtcgtcgtacgctgggtattggtgtgatcaacttc
gcttactacctggcgaagcacggtaaacgctactccgacggcagcgccaacaacctgacg
cataaaaccttcgaagccattcagtattatctgctgaaagcgtctaatgagctggcgaaa
gagcaaggcgcgtgcccgtggtttaacgaaaccacttacgcgaaagggatcctgccgatc
gatacctataagaaagatctggatgccatcgctaatgagccgctgcattacgactgggaa
gcactgcgtgagtcaatcaaaacgcacggcctgcgtaactccacgctttctgccctgatg
ccgtccgagacttcttcgcagatctctaacgccactaacggtattgaaccgccgcgcggt
tacgtcagcatcaaagcgtcgaaagacggtattctgcgccaggtggtgccggactacgag
catctgcacgacgcctatgagctgctgtgggaaatgccgggtaacgatggctacctgcaa
ctggtgggtatcatgcagaaatttatcgatcagtcgatctctgctaacaccaactacgat
ccgtcacgtttcccgtcaggaaaagtgccgatgcaacagttgctgaaagacctgctcacc
gcctacaaattcggggtcaaaacgctgtattatcagaacacccgtgacggcgcagaagac
gcgcaggacgatctggtgccgtcaatccaggacgatggctgcgaaagcggcgcatgtaag
atctga

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