Escherichia coli K-12 MG1655: b2026
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Entry
b2026 CDS
T00007
Symbol
hisI
Name
(RefSeq) putative bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase
KO
K11755
phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase [EC:
3.5.4.19
3.6.1.31
]
Organism
eco
Escherichia coli K-12 MG1655
Pathway
eco00340
Histidine metabolism
eco01100
Metabolic pathways
eco01110
Biosynthesis of secondary metabolites
eco01230
Biosynthesis of amino acids
Module
eco_M00026
Histidine biosynthesis, PRPP => histidine
Brite
KEGG Orthology (KO) [BR:
eco00001
]
09100 Metabolism
09105 Amino acid metabolism
00340 Histidine metabolism
b2026 (hisI)
Enzymes [BR:
eco01000
]
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.19 phosphoribosyl-AMP cyclohydrolase
b2026 (hisI)
3.6 Acting on acid anhydrides
3.6.1 In phosphorus-containing anhydrides
3.6.1.31 phosphoribosyl-ATP diphosphatase
b2026 (hisI)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PRA-CH
PRA-PH
MazG
Motif
Other DBs
NCBI-GeneID:
946515
NCBI-ProteinID:
NP_416530
Pasteur:
hisI
RegulonDB:
ECK120000444
ECOCYC:
EG10451
ASAP:
ABE-0006729
UniProt:
P06989
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All DBs
Position
2096614..2097225
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AA seq
203 aa
AA seq
DB search
MLTEQQRRELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPEALDKTLESGKVTFFSRTKQR
LWTKGETSGNFLNVVSIAPDCDNDTLLVLANPIGPTCHKGTSSCFGDTAHQWLFLYQLEQ
LLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALAATVHDRFELTNEASDLMYHL
LVLLQDQGLDLTTVIENLRKRHQ
NT seq
612 nt
NT seq
+upstream
nt +downstream
nt
atgttaacagaacaacaacgtcgcgaactggactgggaaaaaaccgacggacttatgccg
gtgattgtgcaacacgcggtatccggcgaagtgctaatgctgggctatatgaacccggaa
gccttagacaaaaccctcgaaagcggcaaagtcaccttcttctcgcgcactaaacagcga
ctgtggaccaaaggcgaaacgtcgggcaatttcctcaacgtagtgagtattgccccggac
tgcgacaacgacacgttactggtgctggcgaatcccatcggcccgacctgccacaaaggc
accagcagttgcttcggcgacaccgctcaccagtggctgttcctgtatcaactggaacaa
ctgctcgccgagcgcaaatctgccgatccggaaacctcctacaccgccaaactgtatgcc
agcggcaccaaacgcattgcgcagaaagtgggtgaagaaggcgtggaaaccgcgctggca
gcaacggtacatgaccgctttgagctgaccaacgaggcgtctgatttgatgtatcacctg
ctggtgttgttgcaggatcaggggctggatttaacgacggtaattgagaacctgcgtaaa
cggcatcagtga
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