Escherichia coli K-12 MDS42: ECMDS42_2842
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Entry
ECMDS42_2842 CDS
T02541
Symbol
mrcA
Name
(GenBank) fused penicillin-binding protein 1a murein transglycosylase/murein transpeptidase
KO
K05366
penicillin-binding protein 1A [EC:
2.4.99.28
3.4.16.4
]
Organism
ecok
Escherichia coli K-12 MDS42
Pathway
ecok00550
Peptidoglycan biosynthesis
ecok01100
Metabolic pathways
ecok01501
beta-Lactam resistance
Brite
KEGG Orthology (KO) [BR:
ecok00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ECMDS42_2842 (mrcA)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01501 beta-Lactam resistance
ECMDS42_2842 (mrcA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01003 Glycosyltransferases [BR:
ecok01003
]
ECMDS42_2842 (mrcA)
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
ecok01011
]
ECMDS42_2842 (mrcA)
Enzymes [BR:
ecok01000
]
2. Transferases
2.4 Glycosyltransferases
2.4.99 Transferring other glycosyl groups
2.4.99.28 peptidoglycan glycosyltransferase
ECMDS42_2842 (mrcA)
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.16 Serine-type carboxypeptidases
3.4.16.4 serine-type D-Ala-D-Ala carboxypeptidase
ECMDS42_2842 (mrcA)
Glycosyltransferases [BR:
ecok01003
]
Polysaccharide
Bacterial polysaccharide (excluding LPS)
ECMDS42_2842 (mrcA)
Peptidoglycan biosynthesis and degradation proteins [BR:
ecok01011
]
Peptidoglycan biosynthesis and degradation
Glycosyltransferase/DD-Transpeptidase (Class A PBP)
ECMDS42_2842 (mrcA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Transgly
PCB_OB
Transpeptidase
DUF3502
Motif
Other DBs
NCBI-ProteinID:
BAL40010
LinkDB
All DBs
Position
2974797..2977349
Genome browser
AA seq
850 aa
AA seq
DB search
MKFVKYFLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRLQIPMQIYSADGELIAQ
YGEKRRIPVTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGAST
ITQQLARNFFLSPERTLMRKIKEVFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAA
QVYFGKTVDQLTLNEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQQQF
DQTRTEAINANYHAPEIAFSAPYLSEMVRQEMYNRYGESAYEDGYRIYTTITRKVQQAAQ
QAVRNNVLDYDMRHGYRGPANVLWKVGESAWDNNKITDTLKALPTYGPLLPAAVTSANPQ
QATAMLADGSTVALSMEGVRWARPYRSDTQQGPTPRKVTDVLQTGQQIWVRQVGDAWWLA
QVPEVNSALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGL
TLASMLNDVPISRWDASAGSDWQPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDY
AAEYLQRFGFPAQNIVHTESLALGSASFTPMQVARGYAVMANGGFLVDPWFISKIENDQG
GVIFEAKPKVACPECDIPVIYGDTQKSNVLENNDVEDVAISREQQNVSVPMPQLEQANQA
LVAKTGAQEYAPHVINTPLAFLIKSALNTNIFGEPGWQGTGWRAGRDLQRRDIGGKTGTT
NSSKDAWFSGYGPGVVTSVWIGFDDHRRNLGHTTASGAIKDQISGYEGGAKSAQPAWDAY
MKAVLEGVPEQPLTPPPGIVTVNIDRSTGQLANGGNSREEYFIEGTQPTQQAVHEVGTTI
IDNGEAQELF
NT seq
2553 nt
NT seq
+upstream
nt +downstream
nt
gtgaagttcgtaaagtattttttgatccttgcagtctgttgcattctgctgggagcaggc
tcgatttatggcctataccgctacatcgagccacaactgccggatgtggcgacattaaaa
gatgttcgcctgcaaattccgatgcagatttacagcgccgatggcgagctgattgctcaa
tacggtgagaaacgtcgtattccggttacgttggatcaaatcccaccggagatggtgaaa
gcctttatcgcgacagaagacagccgcttctacgagcatcacggcgttgacccggtgggg
atcttccgtgcagcaagcgtggcgctgttctccggtcacgcgtcacaaggggcaagtacc
attacccagcagctggcgagaaacttcttcctcagtccagaacgcacgctgatgcgtaag
attaaggaagtcttcctcgcgattcgcattgaacagctgctgacgaaagacgagatcctc
gagctttatctgaacaagatttaccttggttaccgcgcctatggtgtcggtgctgcggca
caagtctatttcggaaaaacggtcgaccaactgacgctgaacgaaatggcggtgatagcc
gggctgccgaaagcgccttccaccttcaacccgctctactcgatggatcgtgccgtcgcg
cggcgtaacgtcgtgctgtcgcggatgctggatgaagggtatatcacccaacaacagttc
gatcagacacgcactgaggcgattaacgctaactatcacgcgccggagattgctttctct
gcgccgtacctgagcgaaatggtgcgccaggagatgtataaccgttatggcgaaagtgcc
tatgaagacggttatcgcatttacaccaccatcacccgcaaagtgcagcaggccgcgcag
caggcggtacgtaataacgtgctggactacgacatgcgccacggctatcgcggcccggca
aatgtgctgtggaaagtgggcgagtcggcgtgggataacaacaagattaccgatacgctg
aaggcgctgccaacctatggtccgctgctgcctgccgcagtcaccagcgccaatcctcag
caagcgacggcgatgctggcggacgggtcgaccgtcgcattgagtatggaaggcgttcgc
tgggcgcgtccttaccgttcggatactcagcaaggaccgacgccgcgtaaagtgaccgat
gttctgcaaacgggtcagcaaatctgggttcgtcaggttggcgatgcatggtggctggca
caagtgccggaagtgaactcggcgctggtgtcgatcaatccgcaaaacggtgccgttatg
gcgctggtcggtggctttgatttcaatcagagcaagtttaaccgcgccacccaggcactg
cgtcaggtgggttccaacatcaaaccgttcctctacaccgcggcgatggataaaggtctg
acgctggcaagtatgttgaacgatgtgccaatttctcgctgggatgcaagtgccggttct
gactggcagccgaagaactcaccaccgcagtatgctggtccaattcgcttacgtcagggg
ctgggtcagtcgaaaaacgtggtgatggtacgcgcaatgcgggcgatgggcgtcgactac
gctgcagaatatctgcaacgcttcggcttcccggcacaaaacattgtccacaccgaatcg
ctggcgctgggttcagcgtccttcaccccaatgcaggtggcgcgcggctacgcggtcatg
gcgaacggcggcttcctggtggacccgtggtttatcagcaaaattgaaaacgatcagggc
ggcgtgattttcgaagcgaaaccgaaagtagcctgcccggaatgcgatattccggtgatt
tacggtgatacgcagaaatcgaacgtgctggaaaataacgatgttgaagatgtcgctatc
tcccgcgagcagcagaatgtttctgtaccaatgccgcagctggagcaggcaaatcaggcg
ttagtggcgaagactggcgcgcaggagtacgcaccgcacgtcatcaacactccgctggca
ttcctgattaagagtgctttgaacaccaatatctttggtgagccaggctggcagggtact
ggctggcgtgcaggtcgtgatttgcagcgtcgcgatatcggcgggaaaaccgggaccact
aacagttcgaaagatgcgtggttctcgggttacggtccgggcgttgtgacctcggtctgg
attggctttgatgatcaccgtcgtaatctcggtcatacaacggcttccggagcgattaaa
gatcagatctcaggttacgaaggcggtgccaagagtgcccagcctgcatgggacgcttat
atgaaagccgttcttgaaggtgtgccggagcagccgctgacgccgccaccgggtattgtg
acggtgaatatcgatcgcagcaccgggcagttagctaatggtggcaacagccgcgaagag
tatttcatcgaaggtacgcagccgacacaacaggcagtgcacgaggtgggaacgaccatt
atcgataatggcgaggcacaggaattgttctga
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